[go: up one dir, main page]

SE0300620D0 - A new bone substitute composition - Google Patents

A new bone substitute composition

Info

Publication number
SE0300620D0
SE0300620D0 SE0300620A SE0300620A SE0300620D0 SE 0300620 D0 SE0300620 D0 SE 0300620D0 SE 0300620 A SE0300620 A SE 0300620A SE 0300620 A SE0300620 A SE 0300620A SE 0300620 D0 SE0300620 D0 SE 0300620D0
Authority
SE
Sweden
Prior art keywords
composition
calcium sulfate
new bone
bone substitute
component
Prior art date
Application number
SE0300620A
Other languages
English (en)
Inventor
Lars Lidgren
Malin Nilsson
Original Assignee
Bone Support Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bone Support Ab filed Critical Bone Support Ab
Priority to SE0300620A priority Critical patent/SE0300620D0/sv
Publication of SE0300620D0 publication Critical patent/SE0300620D0/sv
Priority to PT04717912T priority patent/PT1601387E/pt
Priority to US10/547,671 priority patent/US8420127B2/en
Priority to PCT/SE2004/000328 priority patent/WO2004078223A1/en
Priority to DE602004022024T priority patent/DE602004022024D1/de
Priority to CNB2004800097919A priority patent/CN100536932C/zh
Priority to CA2518104A priority patent/CA2518104C/en
Priority to JP2006507949A priority patent/JP4805812B2/ja
Priority to EP04717912A priority patent/EP1601387B1/en
Priority to PL04717912T priority patent/PL1601387T3/pl
Priority to ES04717912T priority patent/ES2330108T3/es
Priority to AU2004218550A priority patent/AU2004218550B2/en
Priority to HK05111471.0A priority patent/HK1079464A1/xx
Priority to US13/799,959 priority patent/US20130268088A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/42Phosphorus; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0409Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0052Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with an inorganic matrix
    • A61L24/0063Phosphorus containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Composite Materials (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SE0300620A 2003-03-05 2003-03-05 A new bone substitute composition SE0300620D0 (sv)

Priority Applications (14)

Application Number Priority Date Filing Date Title
SE0300620A SE0300620D0 (sv) 2003-03-05 2003-03-05 A new bone substitute composition
AU2004218550A AU2004218550B2 (en) 2003-03-05 2004-03-05 A new bone substitute composition
CA2518104A CA2518104C (en) 2003-03-05 2004-03-05 Artificial bone mineral substitute for in vivo hardening
US10/547,671 US8420127B2 (en) 2003-03-05 2004-03-05 Bone substitute composition
PCT/SE2004/000328 WO2004078223A1 (en) 2003-03-05 2004-03-05 A new bone substitute composition
DE602004022024T DE602004022024D1 (de) 2003-03-05 2004-03-05 Neue knochenersatzzusammensetzung
CNB2004800097919A CN100536932C (zh) 2003-03-05 2004-03-05 新的骨替代组合物
PT04717912T PT1601387E (pt) 2003-03-05 2004-03-05 Nova composição para substituição de osso
JP2006507949A JP4805812B2 (ja) 2003-03-05 2004-03-05 新代用骨組成物
EP04717912A EP1601387B1 (en) 2003-03-05 2004-03-05 A new bone substitute composition
PL04717912T PL1601387T3 (pl) 2003-03-05 2004-03-05 Nowa kompozycja substytutu kości
ES04717912T ES2330108T3 (es) 2003-03-05 2004-03-05 Una nueva composcion de sustitutivo de hueso.
HK05111471.0A HK1079464A1 (en) 2003-03-05 2005-12-14 A new bone substitute composition
US13/799,959 US20130268088A1 (en) 2003-03-05 2013-03-13 Bone substitute composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0300620A SE0300620D0 (sv) 2003-03-05 2003-03-05 A new bone substitute composition

Publications (1)

Publication Number Publication Date
SE0300620D0 true SE0300620D0 (sv) 2003-03-05

Family

ID=20290603

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0300620A SE0300620D0 (sv) 2003-03-05 2003-03-05 A new bone substitute composition

Country Status (13)

Country Link
US (2) US8420127B2 (sv)
EP (1) EP1601387B1 (sv)
JP (1) JP4805812B2 (sv)
CN (1) CN100536932C (sv)
AU (1) AU2004218550B2 (sv)
CA (1) CA2518104C (sv)
DE (1) DE602004022024D1 (sv)
ES (1) ES2330108T3 (sv)
HK (1) HK1079464A1 (sv)
PL (1) PL1601387T3 (sv)
PT (1) PT1601387E (sv)
SE (1) SE0300620D0 (sv)
WO (1) WO2004078223A1 (sv)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE520688C2 (sv) * 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
SE517168C2 (sv) * 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
SE522098C2 (sv) * 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
FR2850282B1 (fr) 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
SE0300620D0 (sv) 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
SE0302983D0 (sv) * 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
US20060089723A1 (en) * 2004-10-25 2006-04-27 Murphy Kieran P Method for bone augmentation
US8852240B2 (en) * 2004-10-25 2014-10-07 Kieran Murphy, Llc Methods and compositions for fostering and preserving bone growth
AU2006287478B2 (en) 2005-09-09 2012-02-02 Agnovos Healthcare, Llc Composite bone graft substitute cement and articles produced therefrom
US20070077267A1 (en) * 2005-10-03 2007-04-05 Sdgi Holdings, Inc. Bioactive composite implants
CN101454028B (zh) 2006-05-26 2014-06-04 巴克斯特国际公司 用于骨质增加的可注射纤维蛋白组合物
MX2008014850A (es) * 2006-05-26 2008-12-05 Baxter Int Relleno inyectable de hueco oseo.
EP1958649A1 (en) 2007-02-14 2008-08-20 Graftys Injectable calcium-phosphate cement releasing a bone resorption inhibitor
CA2720269A1 (en) * 2007-04-18 2008-10-30 Mcgill University Composition for enhancing bone formation
EP2139507A4 (en) * 2007-04-27 2012-06-06 Unigene Lab Inc METHODS AND COMPOSITIONS FOR PROMOTING AND CONSERVING BONE GROWTH
EP2077126A1 (en) * 2008-01-07 2009-07-08 Graftys Analgesic apatitic calcium-phosphate cement
WO2009143236A1 (en) * 2008-05-20 2009-11-26 Albert Einstein Healthcare Network Compositions and methods for the treatment of skeletal metastatic lesions and fractures
DE102009001895A1 (de) * 2009-03-26 2010-09-30 Biotronik Vi Patent Ag Medizinisches Implantat zur Medikamentenfreisetzung mit poröser Oberfläche
EP2512537B1 (en) 2009-12-18 2015-08-26 Howmedica Osteonics Corp. Dual paste direct injectable bone cement precursor systems and methods of making same
TW201121591A (en) * 2009-12-29 2011-07-01 Far Eastern New Century Corp Porous bone cement
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
EP2353619A1 (en) 2010-02-09 2011-08-10 Bone Support AB Preparation of Bone Cement Compositions
WO2012057836A2 (en) 2010-10-26 2012-05-03 Cap Biomaterials, Llc Composites of hydroxyapatite and calcium carbonate and related methods of preparation and use
CN102008748B (zh) * 2010-11-08 2013-07-31 胡钢锋 可注射可降解硫酸钙和磷酸钙材料在作为股骨头坏死修复材料中的应用
US10182973B2 (en) 2010-11-10 2019-01-22 Stryker European Holdings I, Llc Polymeric bone foam composition and method
US20120195982A1 (en) * 2011-01-28 2012-08-02 Beijing Allgens Medical Science & Technology Co., Ltd. Injectible, biocompatible synthetic bone growth composition
AU2012358294B2 (en) * 2011-12-23 2016-12-22 Cerapedics, Inc. Implantable materials for bone repair
TWI414327B (zh) * 2012-08-28 2013-11-11 Far Eastern Memorial Hospital 複合性骨水泥
PL2958603T3 (pl) * 2013-02-20 2018-10-31 Bone Support Ab Ulepszone zestalanie utwardzalnego materiału zastępczego kości
EP2970000A1 (en) * 2013-03-14 2016-01-20 Skeletal Kinetics LLC Calcium phosphate cement compositions that set into high strength porous structures
US9827268B2 (en) * 2013-08-06 2017-11-28 Kuraray Noritake Dental Inc. Curable calcium phosphate composition for biological hard tissue repair, bone repair material, and various dental materials
BR112016011515A2 (pt) * 2013-11-21 2020-10-13 The University Of Toledo método para produzir uma composição de cimento
TWI651103B (zh) 2013-12-13 2019-02-21 萊特醫技股份有限公司 多相骨移植替代材料
US20150250610A1 (en) * 2014-03-04 2015-09-10 DePuy Synthes Products, LLC Post-Operative Bone Grown Stimulant Introduction Method
US9487443B2 (en) * 2014-03-14 2016-11-08 Ricoh Company, Ltd. Layer stack formation powder material, powder layer stack formation hardening liquid, layer stack formation material set, and layer stack object formation method
BR112017000473A2 (pt) * 2014-07-10 2017-12-19 Bone Support Ab substitutos de osso injetáveis para aumentar a fixação de implantes
CA2980486A1 (en) 2015-03-23 2016-09-29 Bone Support Ab Biphasic ceramic bone substitute
CN106495682A (zh) * 2015-03-31 2017-03-15 蒋超 生物活性较高、骨骼修复替代用生物陶瓷的制备方法
RU2614360C1 (ru) * 2016-02-24 2017-03-24 федеральное государственное бюджетное образовательное учреждение высшего образования "Тюменский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО Тюменский ГМУ Минздрава России) Способ лечения гематогенного остеомиелита позвоночника
GB2559761A (en) * 2017-02-16 2018-08-22 Corthotec Ltd Composition for improved bone fracture healing
WO2018170185A1 (en) 2017-03-14 2018-09-20 National Taiwan University Composition material and method for free forming bone substitute
CN107670102A (zh) * 2017-11-19 2018-02-09 赵亮 一种募集内源性细胞的骨生物复合材料和制备方法及应用
US11235086B2 (en) 2018-02-22 2022-02-01 Cerapedics, Inc. Processes for coating inorganic particles with a peptide or protein useful for improving cellular activity related to bone growth
EP3903842A1 (en) * 2018-04-23 2021-11-03 Moroxite AB Novel treatment approach by targeted delivery of bioactive molecules bio modulated ceramics
US11529438B2 (en) * 2018-06-25 2022-12-20 Bioventus, Llc Porous carrier matrix
CN110755680B (zh) * 2019-11-25 2022-05-17 中鼎凯瑞科技成都有限公司 负载维生素d的柠檬酸钙/硫酸钙复合骨水泥及制备方法
EP4335466A1 (de) * 2022-09-08 2024-03-13 Heraeus Medical GmbH Zusammensetzung zur herstellung eines knochenersatzmaterials, verfahren zur herstellung eines pharmazeutischen wirkstoffträgers, pharmazeutischer wirkstoffträger sowie dessen verwendung

Family Cites Families (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US949163A (en) 1909-07-07 1910-02-15 Bridgeport Brass Co Grease-gun.
US1644173A (en) 1923-02-01 1927-10-04 Bassick Mfg Co Lubricating apparatus
US1865912A (en) 1930-03-25 1932-07-05 Horn William Oil well agitator
US2545017A (en) 1947-06-02 1951-03-13 Gordon D Billingsley Hypodermic syringe
US3367783A (en) 1966-03-23 1968-02-06 Gerber Prod Process of preparing a fruit gel
US3475010A (en) 1968-04-24 1969-10-28 Prod Res & Chem Corp Dispensing cartridge for intermixing separate ingredients
US3688765A (en) 1969-10-03 1972-09-05 Jack S Gasaway Hypodermic injection device
US3837379A (en) 1973-05-14 1974-09-24 East West Med Prod Irrigator liquid supply system
CH608189A5 (sv) 1974-12-13 1978-12-29 Savac Ag
US3965910A (en) 1975-04-28 1976-06-29 Walpak Company Urinary irrigation valve
CH626873A5 (sv) 1977-03-28 1981-12-15 Bracco Ind Chimica Spa
US4240425A (en) 1978-10-23 1980-12-23 American Hospital Supply Corporation Syringe with plug type needle hub lock
IT1207226B (it) 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
US4338925A (en) 1979-12-20 1982-07-13 Jo Miller Pressure injection of bone cement apparatus and method
US4269331A (en) 1980-02-15 1981-05-26 Watson John D Metered dispensing device
US4496342A (en) 1981-03-20 1985-01-29 Surgical Design Corporation Surge prevention system for an ophthalmic instrument
DE3206911A1 (de) 1982-02-26 1983-09-15 Lohmann Tierernährung GmbH, 2190 Cuxhaven Biochemischer wirkstoff, dessen herstellung und diesen wirkstoff enthaltendes mittel
US4439420A (en) 1982-11-16 1984-03-27 Ethicon, Inc. Absorbable hemostatic composition
US4619655A (en) 1984-01-26 1986-10-28 University Of North Carolina Plaster of Paris as a bioresorbable scaffold in implants for bone repair
US4583974A (en) 1984-04-04 1986-04-22 Kokernak Denis T Syringe for balloon dilation catheters
DK350584A (da) 1984-07-18 1986-01-19 Arne Bent Sjoegren Blandepumpe til effektiv blanding (homogenisering) af to eller flere vaesker (luftarter) med et konstant, men regulerbart, blandingsforhold
SE450545B (sv) 1984-10-19 1987-07-06 Mit Ab Forfarande och anordning vid framstellning av bencement for fixering av proteser
GB8516344D0 (en) 1985-06-28 1985-07-31 Brunold C R Mixing apparatus & processes
US4676655A (en) 1985-11-18 1987-06-30 Isidore Handler Plunger type cartridge mixer for fluent materials
US4752479A (en) 1986-05-27 1988-06-21 Ciba-Geigy Corporaton Multi vitamin and mineral dietary supplement with controlled release bioavailable iron
EP0305417B1 (en) 1987-02-20 1995-06-28 DRAENERT, Klaus, Dr.med. Suction drainage-bone screw
ES2007350A6 (es) 1987-05-29 1989-06-16 Ganadera Union Ind Agro Productos alimenticios enriquecidos con nucleosidos yno nucleotidos para la nutricion infantil y de adultos, y procedimiento para su preparacion.
DE3731542A1 (de) 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
US5605885A (en) 1988-05-05 1997-02-25 Entremed, Inc. Method for stimulating the immune system
GB8919929D0 (en) 1989-09-04 1989-10-18 Nycomed As Compositions
SE464912B (sv) 1989-10-25 1991-07-01 Bioapatite Ab Implantationsmaterial foer aaterstaellning av benvaevnad samt saett foer dess tillverkning
US5236456A (en) 1989-11-09 1993-08-17 Osteotech, Inc. Osteogenic composition and implant containing same
IT1236864B (it) 1989-12-29 1993-04-22 Tecres Spa Procedimento per miscelare e somministrare direttamente in loco un cemento osseo a due componenti, e dispositivo che lo realizza
US5071040A (en) 1990-03-09 1991-12-10 Pfizer Hospital Products Group, Inc. Surgical adhesives mixing and dispensing implement
US5168757A (en) 1990-05-15 1992-12-08 Ryder International Corporation Fluid displacement and pressurizing device
US5269785A (en) 1990-06-28 1993-12-14 Bonutti Peter M Apparatus and method for tissue removal
US5990382A (en) 1990-08-29 1999-11-23 Biomedical Enterprises, Inc. Method and implant for surgical manipulation of bone
US6080801A (en) 1990-09-13 2000-06-27 Klaus Draenert Multi-component material and process for its preparation
US5149368A (en) 1991-01-10 1992-09-22 Liu Sung Tsuen Resorbable bioactive calcium phosphate cement
US5462722A (en) 1991-04-17 1995-10-31 Liu; Sung-Tsuen Calcium phosphate calcium sulfate composite implant material
US5262166A (en) 1991-04-17 1993-11-16 Lty Medical Inc Resorbable bioactive phosphate containing cements
US5232024A (en) 1991-05-30 1993-08-03 Eli Williams Slide-valve manifold
DE69205736T2 (de) 1991-06-26 1996-06-13 Nitta Gelatin Kk Härtbares kalziumphosphathaltiges Material zum Reparieren von lebenden Hartgeweben.
DE4121043A1 (de) 1991-06-26 1993-01-07 Merck Patent Gmbh Knochenersatzmaterial mit fgf
US5281265A (en) 1992-02-03 1994-01-25 Liu Sung Tsuen Resorbable surgical cements
SE510490C2 (sv) 1992-02-07 1999-05-31 Scandimed International Ab Förfarande för framställning av bencement och anordning för genomförande av förfarandet
CA2103683C (en) 1992-08-17 1998-06-16 George Weeks Methods of controlling dust and compositions produced thereby
IT1256248B (it) 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
US5403318A (en) 1993-01-15 1995-04-04 Boehringer Laboratories, Inc. Apparatus and method for shaping bone
SE510491C2 (sv) 1993-08-18 1999-05-31 Coripharm Gmbh & Co Cement för medicinskt bruk samt framställning och användning av cementet
US5665066A (en) 1993-09-03 1997-09-09 Ultradent Products, Inc. Methods and apparatus for mixing and dispensing multi-part compositions
US5681873A (en) 1993-10-14 1997-10-28 Atrix Laboratories, Inc. Biodegradable polymeric composition
US5360823A (en) 1993-11-02 1994-11-01 Dawe's Inc. Anionic salt formulation for milk fever
EP0657208A1 (de) 1993-12-08 1995-06-14 Allo Pro Ag Vorrichtung zum Mischen von einem Mehrkomponentenzement und Verfahren zum Durchführen des Mischvorganges
US6716216B1 (en) 1998-08-14 2004-04-06 Kyphon Inc. Systems and methods for treating vertebral bodies
US6248110B1 (en) 1994-01-26 2001-06-19 Kyphon, Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
DE4409610C3 (de) 1994-03-21 2001-09-20 Scandimed Internat Ab Sjoebo Mischvorrichtung
DE4425218A1 (de) 1994-07-16 1996-01-18 Merck Patent Gmbh Vorrichtung zum Mischen und Austragen von Knochenzement
US6075067A (en) 1994-08-15 2000-06-13 Corpipharm Gmbh & Co Cement for medical use, method for producing the cement, and use of the cement
DE4433201A1 (de) 1994-09-17 1996-03-21 Merck Patent Gmbh Verfahren zur Herstellung von wirkstoffhaltigen Knochenzementen
DE4435680A1 (de) 1994-10-06 1996-04-11 Merck Patent Gmbh Poröse Knochenersatzmaterialien
US5616120A (en) 1995-02-06 1997-04-01 Andrew; Mark S. Method and apparatus for lenticular liquefaction and aspiration
US5614206A (en) 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
WO1997022365A1 (en) 1995-12-19 1997-06-26 Bracco Research S.A. Compositions comprising tricodobenzene polymers for imaging the gastrointestinal tract
US6596904B1 (en) 1996-01-29 2003-07-22 Mallinc Krodt Inc Process for producing ioversol
US6299905B1 (en) 1996-04-16 2001-10-09 Depuy Orthopaedics, Inc. Bioerodable polymeric adhesives for tissue repair
DE19620117C1 (de) 1996-05-18 1997-07-24 Corimed Kundenorientierte Medi Verfahren zur Herstellung eines calciumsulfathaltigen medizinischen Präparats und calciumsulfathaltiges medizinisches Präparat
FR2749756B1 (fr) 1996-06-14 1998-09-11 Bioland Procede de preparation d'un materiau composite implantable, materiau obtenu, implant comprenant ce materiau et kit de mise en oeuvre
US5871549A (en) 1996-12-12 1999-02-16 Johnson & Johnson Professional, Inc. Femoral stem with reduced coefficient of friction with respect to bone cement
US20020076378A1 (en) 1997-01-29 2002-06-20 Nycomed Imaging As Polymers
US5842786A (en) 1997-03-07 1998-12-01 Solomon; Alan Method and device for mixing medical compositions
US5829875A (en) 1997-04-02 1998-11-03 Simpson Strong-Tie Co., Inc. Combined barrier and mixer assembly for a cylindrical container
US6071982A (en) 1997-04-18 2000-06-06 Cambridge Scientific, Inc. Bioerodible polymeric semi-interpenetrating network alloys for surgical plates and bone cements, and method for making same
DE19718648A1 (de) 1997-05-02 1998-11-05 Merck Patent Gmbh Verfahren und Vorrichtung zur Herstellung von steril verpacktem Knochenzement
IT1292037B1 (it) 1997-05-30 1999-01-25 Bracco Spa Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
US5837752A (en) * 1997-07-17 1998-11-17 Massachusetts Institute Of Technology Semi-interpenetrating polymer networks
US6048346A (en) 1997-08-13 2000-04-11 Kyphon Inc. Systems and methods for injecting flowable materials into bones
US6309420B1 (en) 1997-10-14 2001-10-30 Parallax Medical, Inc. Enhanced visibility materials for implantation in hard tissue
WO1999020562A1 (en) 1997-10-20 1999-04-29 Prc-Desoto International, Inc. Multiple part manual dispensing syringe
US6062722A (en) 1997-10-21 2000-05-16 Micron Communications, Inc. Fluid mixing and withdrawing methods
US6440138B1 (en) 1998-04-06 2002-08-27 Kyphon Inc. Structures and methods for creating cavities in interior body regions
DE19816858A1 (de) 1998-04-16 1999-10-21 Merck Patent Gmbh Tricalciumphosphathaltige Biozementpasten mit Kohäsionspromotoren
DE19817762A1 (de) 1998-04-21 1999-10-28 Dietmar Enk Vorrichtung zur intravasalen Druckmessung und kontaminationsarmen Einlage von Kathetern z. B. in Blutgefäse
SE9801901L (sv) 1998-05-29 1999-08-02 Bone Support Ab Förfarande för framställning av pulverkomponent till cement för medicinskt bruk, användning av sådan pulverkomponent samt sådan pulverkomponent
GB2338428A (en) 1998-06-19 1999-12-22 David Grant A syringe with an agitator whose shaft passes through a slidable dispensing plunger
WO2000007639A1 (en) 1998-08-07 2000-02-17 Tissue Engineering, Inc. Bone precursor compositions
DE19853832A1 (de) 1998-11-21 2000-05-25 Merck Patent Gmbh Polyalkensäuren enthaltende Calcium-Phosphatzemente
US6120174A (en) 1999-01-14 2000-09-19 Bristol-Myers Squibb Apparatus and method for mixing and dispensing bone cement
US6447809B1 (en) * 1999-05-11 2002-09-10 Metagenics, Inc. Composition for promoting healthy bone structure
AU6318900A (en) 1999-08-05 2001-03-05 Takeda Chemical Industries Ltd. Pastes with the sustained release of osteogenesis promoter
JP2001106638A (ja) 1999-08-05 2001-04-17 Takeda Chem Ind Ltd 骨形成促進物質徐放性ペースト
DE19938704C1 (de) 1999-08-14 2001-10-31 Ivoclar Vivadent Ag Verfahren zur Herstellung von Reaktionssystemen zur Implantation in den menschlichen und tierischen Körper als Knochenersatz, die u.a. Calcium und Phosphor enthalten
JP2001104324A (ja) 1999-10-06 2001-04-17 Ngk Spark Plug Co Ltd 薬剤押出用補助器具及びそれを用いた薬剤の押出方法
DE19953771C1 (de) 1999-11-09 2001-06-13 Coripharm Medizinprodukte Gmbh Resorbierbares Knochen-Implantatmaterial sowie Verfahren zur Herstellung desselben
EP1155704A1 (en) 2000-01-13 2001-11-21 Chih-I Lin Orthopedic filling material and method of use thereof
US6365218B1 (en) 2000-02-04 2002-04-02 Abbott Laboratories Pediatric formula and methods for providing nutrition and improving tolerance
US6790210B1 (en) 2000-02-16 2004-09-14 Trans1, Inc. Methods and apparatus for forming curved axial bores through spinal vertebrae
US6723334B1 (en) 2000-03-01 2004-04-20 Iowa State University Research Foundation, Inc. Biologically compatible bone cements and orthopedic methods
US6332894B1 (en) 2000-03-07 2001-12-25 Zimmer, Inc. Polymer filled spinal fusion cage
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
SE520688C2 (sv) 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
ES2178556B1 (es) 2000-06-30 2004-07-16 Universitat Politecnica De Catalunya Cemento de sulfato de calcio con biodegradacion controlada.
SE517168C2 (sv) * 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
JP2002058736A (ja) 2000-08-17 2002-02-26 Seikagaku Kogyo Co Ltd 骨充填用組成物、骨充填用医療用具及び骨充填用キット
US20020193883A1 (en) * 2001-01-25 2002-12-19 Wironen John F. Injectable porous bone graft materials
US7008433B2 (en) 2001-02-15 2006-03-07 Depuy Acromed, Inc. Vertebroplasty injection device
AU2002244520B2 (en) * 2001-04-03 2007-05-24 The Royal Alexandra Hospital For Children A drug for use in bone grafting
ITMI20010773A1 (it) 2001-04-11 2002-10-11 Chemi Spa Processo per la produzione di ioexolo ad elevata purezza
GB0110726D0 (en) 2001-05-02 2001-06-27 Biocomposites Ltd Bone implant composition
JP2002325831A (ja) 2001-05-02 2002-11-12 Asahi Optical Co Ltd 生体用充填材、および生体用充填材の製造方法
US20030055512A1 (en) 2001-05-21 2003-03-20 Genin Francois Y. Calcium based neutral and bioresorbable bone graft
US6547432B2 (en) 2001-07-16 2003-04-15 Stryker Instruments Bone cement mixing and delivery device for injection and method thereof
US20030028251A1 (en) 2001-07-30 2003-02-06 Mathews Hallett H. Methods and devices for interbody spinal stabilization
US6706069B2 (en) 2001-09-13 2004-03-16 J. Lee Berger Spinal grooved director with built in balloon
WO2003037165A2 (en) 2001-11-01 2003-05-08 Boyd Lawrence M System and method for the pretreatment of the endplates of an intervertebral disc
ES2545256T3 (es) * 2001-11-14 2015-09-09 Ecole polytechnique fédérale de Lausanne (EPFL) Multicomponentes pastosos para cementos fosfocálcicos inyectables
JP4499327B2 (ja) 2001-12-06 2010-07-07 松崎 浩巳 拡径器具および手術器具セット
SE522098C2 (sv) 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
ES2289172T3 (es) * 2001-12-20 2008-02-01 Bone Support Ab Un nuevo sustituto mineral de hueso.
US6780191B2 (en) 2001-12-28 2004-08-24 Yacmur Llc Cannula system
DE60305036T2 (de) 2002-06-19 2006-10-12 Dr. H.C. Robert Mathys Stiftung Hydraulischer zement auf basis von calciumphosphat für chirurgische anwendungen
SE524714C2 (sv) 2002-06-28 2004-09-21 Asept Medical Ab Beredare och applikator för bencement
DE10242984B4 (de) 2002-09-17 2010-09-23 Sanatis Gmbh Vorrichtung zum Herstellen von Gemischen aus zwei Komponenten
US20050287071A1 (en) 2002-12-03 2005-12-29 Kyphon Inc. Formulation for a cement preparation as bone substitute
CA2516113A1 (en) 2003-02-13 2004-08-26 Synthes (U.S.A.) Injectable bone-replacement mixture
US6905485B2 (en) 2003-02-19 2005-06-14 Becton, Dickinson And Company Medical device with needle safety shielding
US7393493B2 (en) * 2003-02-27 2008-07-01 A Enterprises, Inc. Crosslinkable polymeric materials and their applications
SE0300620D0 (sv) 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
EP1608734A4 (en) 2003-03-31 2006-11-22 Cleveland Clinic Foundation DEVICE AND METHOD FOR OBTAINING BONE MARROW
US20040267272A1 (en) 2003-05-12 2004-12-30 Henniges Bruce D Bone cement mixing and delivery system
US20050015074A1 (en) 2003-07-17 2005-01-20 Trombley Frederick W. Medical connector, fluid delivery system, and method of use therefor
US7306786B2 (en) 2003-07-28 2007-12-11 Skeletal Kinetics, Llc Calcium phosphate cements comprising a water-soluble contrast agent
SE0302983D0 (sv) 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
US7524103B2 (en) 2003-11-18 2009-04-28 Boston Scientific Scimed, Inc. Apparatus for mixing and dispensing a multi-component bone cement
DE602004006442T2 (de) 2003-12-01 2008-01-10 Broockeville Corp. N.V., Willemstad Zweikomponentenmisch- und -ausgabevorrichtung
EP1742680B1 (en) 2004-04-27 2012-10-24 Kyphon SÀRL Bone substitute compositions and method of use
US20050257714A1 (en) 2004-05-20 2005-11-24 Constantz Brent R Orthopedic cements comprising a barium apatite contrast agent
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
US7776073B2 (en) 2004-06-30 2010-08-17 Depuy Spine, Inc. In-situ formed posterolateral fusion system
US20070198019A1 (en) 2004-07-29 2007-08-23 X-Sten Corp. Spinal ligament modification devices
SE528360C2 (sv) 2004-09-10 2006-10-24 Doxa Ab Resorberbara keramiska kompositioner avsedda för medicinska implantat
US7717918B2 (en) 2004-12-06 2010-05-18 Dfine, Inc. Bone treatment systems and methods
US20080065088A1 (en) 2006-09-07 2008-03-13 Wyeth Bone Cement Mixing Systems and Related Methods
US7666160B2 (en) 2006-12-29 2010-02-23 Kimberly-Clark Worldwide, Inc. Delivery device
US20100249753A1 (en) 2009-02-25 2010-09-30 Gaisser David M Vented syringe system and method for the containment, mixing and ejection of wetted particulate material

Also Published As

Publication number Publication date
JP4805812B2 (ja) 2011-11-02
EP1601387A1 (en) 2005-12-07
US20070041906A1 (en) 2007-02-22
CN1829543A (zh) 2006-09-06
ES2330108T3 (es) 2009-12-04
CN100536932C (zh) 2009-09-09
EP1601387B1 (en) 2009-07-15
US8420127B2 (en) 2013-04-16
CA2518104A1 (en) 2004-09-16
WO2004078223A1 (en) 2004-09-16
HK1079464A1 (en) 2006-04-07
US20130268088A1 (en) 2013-10-10
CA2518104C (en) 2013-02-05
AU2004218550B2 (en) 2009-06-04
AU2004218550A1 (en) 2004-09-16
PT1601387E (pt) 2009-10-19
DE602004022024D1 (de) 2009-08-27
JP2006519082A (ja) 2006-08-24
PL1601387T3 (pl) 2009-12-31

Similar Documents

Publication Publication Date Title
SE0300620D0 (sv) A new bone substitute composition
DE60116098D1 (de) Zusammensetzung für einen injizierbaren knochenmineral ersatz
WO2007030616A3 (en) Composite bone graft substitute cement and articles produced therefrom
ATE340152T1 (de) Verfahren zur erhärtung von einer flüssigen masse
BRPI0406927A (pt) Método de produção de uma mistura cimentosa de arraste de ar contendo cinza estável
WO2007067561A3 (en) Porous calcium phosphate bone material
WO2006014886A3 (en) Calcium phosphate cements and methods for using the same
WO2010055483A3 (en) Hydraulic cements, methods and products
WO2008005509A3 (en) Methods and compositions for altering biological surfaces
MY153414A (en) Slurry compositions and methods for making same
BRPI0613166B8 (pt) copolímero à base de monômeros contendo fósforo, processo para sua preparação e seu uso
DE602007012693D1 (de) Injizierbare fibrin-zusammensetzung zur knochenverstärkung
TR201909466T4 (tr) Düşük serbest stearik asit içeren veya tespit edilebilen hiç serbest stearik asit içermeyen, stearik asitle işlenmiş kalsiyum karbonat bileşimleri ve ilgili yöntemler.
DE60131145D1 (de) Verfahren zur herstellung eines pastösen, injizierbaren kalziumphosphatmaterials
MX370716B (es) Material multifásico sustituto de injerto de hueso.
ATE505215T1 (de) Zusammmensetzung für injizierbaren zement als knochenersatz
EP0945119A3 (en) Calcium phosphate cements and calcium phosphate cement compositions
WO2005048877A3 (en) Calcium phosphate cements comprising an osteoclastogenic agent
JP2014159521A (ja) 地盤改良用混合材及び地盤改良方法
BRPI0520241A2 (pt) acelerador de gesso émido e mÉtodos, composiÇço e produto relacionados ao mesmo
BR112021019169A2 (pt) Processo para produção de hidroxiapatita ou hidroxiapatita modificada, hidroxiapatita ou uma mistura de hidroxiapatita e beta-fosfato tricálcico, composições fotoprotetoras cosmética e para plantas, e, uso de pós
DE602006020918D1 (de) Verwendung von pulverisiertem glas in einem verbundwerkstoff
JP2009013037A (ja) セメント組成物およびその製造方法
ATE383175T1 (de) Injizierbarer komposit für die magnetozytolyse von knochenmetastasezellen
BR112023017427A2 (pt) Cimento hidráulico à base de silicato de cálcio para formar um material compósito tendo propriedades de reforço