SA515360233B1 - مثبطات إنزيمات هستون ديميثيلاز - Google Patents
مثبطات إنزيمات هستون ديميثيلازInfo
- Publication number
- SA515360233B1 SA515360233B1 SA515360233A SA515360233A SA515360233B1 SA 515360233 B1 SA515360233 B1 SA 515360233B1 SA 515360233 A SA515360233 A SA 515360233A SA 515360233 A SA515360233 A SA 515360233A SA 515360233 B1 SA515360233 B1 SA 515360233B1
- Authority
- SA
- Saudi Arabia
- Prior art keywords
- compounds
- inhibitors
- histone demethylases
- present application
- discloses
- Prior art date
Links
- 102000008157 Histone Demethylases Human genes 0.000 title abstract 3
- 108010074870 Histone Demethylases Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000008482 dysregulation Effects 0.000 abstract 1
- 230000008506 pathogenesis Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
يتعلق الاختراع الحالي بالكشف عن مركبات يمكنها تعديل نشاط إنزيمات هستون ديميثيلاز histone demethylases (HDMEs), تكون مفيدة للوقاية من و/ أو علاج الأمراض التي يشترك فيها خلل التنظيم الجينومي genomic في تكوين الأمراض, مثل على سبيل المثال، سرطان cancer. يكشف الطلب الحالي أيضاً عن تركيبات صيدلانية تشتمل على المركبات المذكورة واستخدام مثل هذه المركبات كدواء. تأخذ المركبات صورة (I). (I)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261708806P | 2012-10-02 | 2012-10-02 | |
| DKPA201200599 | 2012-10-02 | ||
| US201361770050P | 2013-02-27 | 2013-02-27 | |
| DKPA201370112 | 2013-02-27 | ||
| PCT/EP2013/070457 WO2014053491A1 (en) | 2012-10-02 | 2013-10-01 | Inhibitors of histone demethylases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SA515360233B1 true SA515360233B1 (ar) | 2017-11-12 |
Family
ID=71451029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SA515360233A SA515360233B1 (ar) | 2012-10-02 | 2015-04-02 | مثبطات إنزيمات هستون ديميثيلاز |
Country Status (2)
| Country | Link |
|---|---|
| EC (1) | ECSP15017165A (ar) |
| SA (1) | SA515360233B1 (ar) |
-
2015
- 2015-04-02 SA SA515360233A patent/SA515360233B1/ar unknown
- 2015-04-30 EC ECIEPI201517165A patent/ECSP15017165A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1247920A1 (zh) | 2018-10-05 |
| ECSP15017165A (es) | 2016-01-29 |
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