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RU96114745A - METHOD OF DIAGNOSTICS OF ONCOLOGICAL DISEASES AND DEVICE FOR ITS IMPLEMENTATION - Google Patents

METHOD OF DIAGNOSTICS OF ONCOLOGICAL DISEASES AND DEVICE FOR ITS IMPLEMENTATION

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Publication number
RU96114745A
RU96114745A RU96114745/14A RU96114745A RU96114745A RU 96114745 A RU96114745 A RU 96114745A RU 96114745/14 A RU96114745/14 A RU 96114745/14A RU 96114745 A RU96114745 A RU 96114745A RU 96114745 A RU96114745 A RU 96114745A
Authority
RU
Russia
Prior art keywords
spectrum
tissue
normal tissue
radiation
suspected
Prior art date
Application number
RU96114745/14A
Other languages
Russian (ru)
Other versions
RU2184486C2 (en
Inventor
С.М. Вовк
С.В. Кондратов
С.А. Наумов
С.С. Олефиренко
В.И. Петров
С.В. Пушкарев
Е.С. Смолянинов
С.А. Стафеев
Original Assignee
Техноцентр "Лазерная диагностика и чистые технологии"
Filing date
Publication date
Application filed by Техноцентр "Лазерная диагностика и чистые технологии" filed Critical Техноцентр "Лазерная диагностика и чистые технологии"
Priority to RU96114745/14A priority Critical patent/RU2184486C2/en
Priority claimed from RU96114745/14A external-priority patent/RU2184486C2/en
Publication of RU96114745A publication Critical patent/RU96114745A/en
Application granted granted Critical
Publication of RU2184486C2 publication Critical patent/RU2184486C2/en

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Claims (2)

1. Способ диагностики онкологических заболеваний, включающий тестирование органов известными физическими методами, исследование подозреваемой ткани путем возбуждения ее пучком монохроматического света с получением спектра флуоресценции и сравнения его с аналогичным спектром нормальной ткани с последующей компьютерной обработкой результатов исследований, отличающийся тем, что перед исследованием подозреваемой ткани осуществляют исследование нормальной ткани того же органа путем возбуждения ее пучком монохроматического света и последующего возбуждения ее пучком полихроматического света в диапазоне длин волн 400 - 800 нм с получением спектра отражения, а при исследовании подозреваемой ткани перед получением спектра флуоресценции возбуждают ее пучком полихроматического света с получением спектра отражения, который сравнивают с аналогичным спектром нормальной ткани; о состоянии подозреваемой ткани судят по соотношению
Figure 00000001

где Imax - интенсивность максимума линии спектра в области 590 - 605 нм;
1(578) - интенсивность минимума линии спектра в точке 578 нм, соответствующего пику поглощения крови;
Imaxn, 1(578)n - для нормальной ткани;
Imaxc, 1(578)c - для подозреваемой ткани,
причем, при q~0- - диагностируют нормальную ткань, а при g o < g < O - наличие онкологического заболевания с конкретизацией вида опухолей по величине q.
1. A method for diagnosing cancer, including testing organs with known physical methods, examining a suspected tissue by exciting it with a beam of monochromatic light to produce a fluorescence spectrum and comparing it with a similar spectrum of normal tissue followed by computer processing of research results, characterized in that carry out the study of normal tissue of the same organ by exciting it with a beam of monochromatic light and following excitation with a beam of polychromatic light in a wavelength range of 400 - 800 nm to obtain the reflection spectrum, and in the investigation of suspected tissue to produce fluorescence spectra excited with a beam of polychromatic light to obtain a reflection spectrum, which is compared with a similar spectrum of normal tissue; the condition of the suspected tissue is judged by the ratio
Figure 00000001

where I max - the intensity of the maximum of the spectrum line in the region of 590 - 605 nm;
1 (578) is the intensity of the minimum of the spectrum line at the point 578 nm, corresponding to the peak of blood absorption;
I maxn , 1 (578) n - for normal tissue;
I maxc , 1 (578) c - for the suspected tissue,
moreover, when q ~ 0-, normal tissue is diagnosed, and when go <g <O, the presence of oncological disease with specification of the type of tumors by q value.
2. Прибор для диагностики онкологических заболеваний, состоящий из источника светового излучения, оптического блока связи, системы подачи и сбора излучения, анализатора спектров и компьютера, отличающийся тем, что он содержит дополнительный источник излучения, а система подачи и сбора излучения смонтирована с разовой медицинской иглой, имеющей внутри моноволоконный жесткий световод. 2. A device for diagnosing cancer diseases, consisting of a source of light radiation, an optical communication unit, a radiation supply and acquisition system, a spectrum analyzer and a computer, characterized in that it contains an additional radiation source, and the radiation delivery and acquisition system is mounted with a single medical needle having inside monofilament hard fiber.
RU96114745/14A 1996-08-06 1996-08-06 Method and device for diagnosing oncological diseases RU2184486C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU96114745/14A RU2184486C2 (en) 1996-08-06 1996-08-06 Method and device for diagnosing oncological diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU96114745/14A RU2184486C2 (en) 1996-08-06 1996-08-06 Method and device for diagnosing oncological diseases

Publications (2)

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RU96114745A true RU96114745A (en) 1998-11-10
RU2184486C2 RU2184486C2 (en) 2002-07-10

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2276786C1 (en) * 2005-01-24 2006-05-20 Сергей Григорьевич Алексеев Method and device for diagnosing oncologic diseases
RU2474386C2 (en) * 2007-06-01 2013-02-10 Конинклейке Филипс Электроникс, Н.В. Wireless ultrasound probe cable
US9155471B2 (en) * 2009-05-27 2015-10-13 Lumicell, Inc'. Methods and systems for spatially identifying abnormal cells
RU2709830C1 (en) * 2018-12-21 2019-12-23 Федеральное государственное бюджетное образовательное учреждение высшего образования "ОРЛОВСКИЙ ГОСУДАРСТВЕННЫЙ УНИВЕРСИТЕТ имени И.С. ТУРГЕНЕВА" (ОГУ им. И.С. Тургенева) Device for fluorescent-reflective spectroscopy for diagnosing focal and diffuse new growths in a fine-needle puncture-aspiration biopsy

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