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RU94045951A - Покровный материал и способ его получения, имплантант для биомедицинского использования - Google Patents

Покровный материал и способ его получения, имплантант для биомедицинского использования

Info

Publication number
RU94045951A
RU94045951A RU94045951/14A RU94045951A RU94045951A RU 94045951 A RU94045951 A RU 94045951A RU 94045951/14 A RU94045951/14 A RU 94045951/14A RU 94045951 A RU94045951 A RU 94045951A RU 94045951 A RU94045951 A RU 94045951A
Authority
RU
Russia
Prior art keywords
implant
biomedical use
biomedicinal
preparing
covering material
Prior art date
Application number
RU94045951/14A
Other languages
English (en)
Other versions
RU2124329C1 (ru
Inventor
Ли Паньян
Cn]
Кангасниеми Илькка
Fi]
Original Assignee
Аксиденталь Ой (FI)
Аксиденталь Ой
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аксиденталь Ой (FI), Аксиденталь Ой filed Critical Аксиденталь Ой (FI)
Publication of RU94045951A publication Critical patent/RU94045951A/ru
Application granted granted Critical
Publication of RU2124329C1 publication Critical patent/RU2124329C1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Prostheses (AREA)

Abstract

Гелеобразный на основе окиси титана материал покрытия для биомедицинского применения, имеющий множество групп TiOH, способный вызывать образование апатита на поверхности покрытия при условиях in vitro и/или осаждение фосфата кальция при условиях in vivo; данный материал может дополнительно содержать один или более следующих элементов, или окислов: Ca, P, Si, Na, K, B, Mg или Al, и на его основе может быть создан имплантант для биомедицинского использования.

Claims (1)

  1. Гелеобразный на основе окиси титана материал покрытия для биомедицинского применения, имеющий множество групп TiOH, способный вызывать образование апатита на поверхности покрытия при условиях in vitro и/или осаждение фосфата кальция при условиях in vivo; данный материал может дополнительно содержать один или более следующих элементов, или окислов: Ca, P, Si, Na, K, B, Mg или Al, и на его основе может быть создан имплантант для биомедицинского использования.
RU94045951/14A 1992-04-23 1993-04-21 Покровный материал и способ его получения (варианты), и имплантат для биомедицинского использования (варианты) RU2124329C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI921802A FI91713C (fi) 1992-04-23 1992-04-23 Uusia bioaktiivisia pinnotteita ja niiden valmistus ja käyttö
FI921802 1992-04-23
PCT/FI1993/000163 WO1993021969A1 (en) 1992-04-23 1993-04-21 Novel bioactive coatings and their preparation and use

Publications (2)

Publication Number Publication Date
RU94045951A true RU94045951A (ru) 1996-09-20
RU2124329C1 RU2124329C1 (ru) 1999-01-10

Family

ID=8535165

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94045951/14A RU2124329C1 (ru) 1992-04-23 1993-04-21 Покровный материал и способ его получения (варианты), и имплантат для биомедицинского использования (варианты)

Country Status (14)

Country Link
US (1) US5612049A (ru)
EP (1) EP0642362B1 (ru)
JP (1) JP3220150B2 (ru)
KR (1) KR950700764A (ru)
AT (1) ATE174803T1 (ru)
AU (1) AU672198B2 (ru)
CA (1) CA2118036C (ru)
DE (1) DE69322779T2 (ru)
DK (1) DK0642362T3 (ru)
ES (1) ES2125979T3 (ru)
FI (1) FI91713C (ru)
GR (1) GR3029407T3 (ru)
RU (1) RU2124329C1 (ru)
WO (1) WO1993021969A1 (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999066966A1 (fr) * 1998-06-22 1999-12-29 Anatoly Dosta Revetement de type film fin pour implant osseux

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
DE4431401A1 (de) * 1994-08-24 1996-02-29 Max Delbrueck Centrum Lebendvakzine gegen Tumorerkrankungen
DE4431862C2 (de) * 1994-09-07 1997-12-11 Dot Duennschicht Und Oberflaec Verfahren zur Beschichtung von Metall- und Keramikoberflächen mit Hydroxylapatit
JP2795824B2 (ja) * 1995-05-12 1998-09-10 オオタ株式会社 チタン系インプラントの表面処理方法及び生体親和性チタン系インプラント
US6764690B2 (en) * 1996-05-29 2004-07-20 Delsitech Oy Dissolvable oxides for biological applications
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US6387700B1 (en) 1996-11-04 2002-05-14 The Reagents Of The University Of Michigan Cationic peptides, Cys-Trp-(LYS)n, for gene delivery
JP3275032B2 (ja) * 1997-03-03 2002-04-15 独立行政法人産業技術総合研究所 環境浄化材料及びその製造方法
US6139585A (en) * 1998-03-11 2000-10-31 Depuy Orthopaedics, Inc. Bioactive ceramic coating and method
US6736849B2 (en) 1998-03-11 2004-05-18 Depuy Products, Inc. Surface-mineralized spinal implants
US6395253B2 (en) 1998-04-23 2002-05-28 The Regents Of The University Of Michigan Microspheres containing condensed polyanionic bioactive agents and methods for their production
US6770740B1 (en) 1999-07-13 2004-08-03 The Regents Of The University Of Michigan Crosslinked DNA condensate compositions and gene delivery methods
EP1339502B1 (de) * 2000-12-04 2004-09-29 Grüssner, Uwe Emil Vorrichtung zur Beschichtung eines Gegenstands mit einem Wirkstoff und Verfahren zur Herstellung eines partiellen oder vollständigen Wirkstoffüberzuges auf und im Implantaten und Onplantaten sowie Verwendung dieses Verfahrens und durch dieses Verfahren hergestelltes Erzeugnis
US20040126406A1 (en) * 2001-05-02 2004-07-01 Tadashi Kokubo Anatase-type titanium dioxide/organic polymer composite materials suitable for artificial bone
DE10161827A1 (de) * 2001-12-15 2003-06-26 Dot Gmbh Verfahren zur Beschichtung eines Substrats mit Calciumphosphat
US7132015B2 (en) * 2002-02-20 2006-11-07 University Of Southern California Materials for dental and biomedical application
US8580291B2 (en) * 2002-03-15 2013-11-12 The Trustees Of The University Of Pennsylvania Fibrous composite for tissue engineering
RU2313370C2 (ru) * 2002-04-09 2007-12-27 Астра Тек АБ Медицинские протезы, имеющие улучшенную биологическую совместимость
US7410502B2 (en) * 2002-04-09 2008-08-12 Numat As Medical prosthetic devices having improved biocompatibility
GB0208642D0 (en) * 2002-04-16 2002-05-22 Accentus Plc Metal implants
DE10243132B4 (de) * 2002-09-17 2006-09-14 Biocer Entwicklungs Gmbh Antiinfektiöse, biokompatible Titanoxid-Beschichtungen für Implantate sowie Verfahren zu deren Herstellung
US6931278B1 (en) 2002-12-06 2005-08-16 Pacesetter, Inc. Implantable cardioverter defibrillator having fast action operation
US7067169B2 (en) * 2003-06-04 2006-06-27 Chemat Technology Inc. Coated implants and methods of coating
US20040267376A1 (en) * 2003-06-25 2004-12-30 Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd) Ceramic member for medical implant and its production method
US7419680B2 (en) * 2003-10-01 2008-09-02 New York University Calcium phosphate-based materials containing zinc, magnesium, fluoride and carbonate
US9199005B2 (en) * 2003-10-01 2015-12-01 New York University Calcium phosphate-based materials containing zinc, magnesium, fluoride and carbonate
GB0405680D0 (en) * 2004-03-13 2004-04-21 Accentus Plc Metal implants
US7785648B2 (en) * 2004-09-22 2010-08-31 New York University Adherent apatite coating on titanium substrate using chemical deposition
US8814567B2 (en) * 2005-05-26 2014-08-26 Zimmer Dental, Inc. Dental implant prosthetic device with improved osseointegration and esthetic features
US7344643B2 (en) * 2005-06-30 2008-03-18 Siemens Water Technologies Holding Corp. Process to enhance phosphorus removal for activated sludge wastewater treatment systems
US8562346B2 (en) 2005-08-30 2013-10-22 Zimmer Dental, Inc. Dental implant for a jaw with reduced bone volume and improved osseointegration features
JP5438967B2 (ja) 2005-08-30 2014-03-12 ジマー デンタル， インコーポレイテッド 改良されたオッセオインテグレーションの特徴を有する歯科用インプラント
JP5523709B2 (ja) 2005-11-14 2014-06-18 バイオメット・３アイ・エルエルシー インプラント表面上に別個のナノ粒子を堆積させる方法
ITFI20060034A1 (it) * 2006-02-03 2007-08-04 Colorobbia Italiana Spa Processo per la funzionalizzazione di superfici metalliche in titanio con particelle di titanio nanometriche e prodotti cosi' funzionalizzati
TW200744679A (en) * 2006-06-09 2007-12-16 Atomic Energy Council Plasma preparation method for containing titanium dioxide of multifunctional polymeric biomaterial
EP2026852B1 (en) * 2006-06-12 2011-01-12 Accentus Medical plc Metal implants
WO2008038293A2 (en) * 2006-09-27 2008-04-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Electrochemical co-deposition of sol-gel films
JP2010508942A (ja) * 2006-11-10 2010-03-25 サンドビック インテレクチュアル プロパティー アクティエボラーグ 外科インプラント複合材料およびキットおよび製造方法
WO2008087448A1 (en) * 2007-01-15 2008-07-24 Accentus Plc Metal implants
US9149345B2 (en) * 2007-08-30 2015-10-06 Zimmer Dental, Inc. Multiple root implant
GB2456853B (en) 2007-10-03 2013-03-06 Accentus Medical Plc Metal treatment
JP5806466B2 (ja) 2008-01-28 2015-11-10 バイオメット・３アイ・エルエルシー 親水性を向上させたインプラント表面
US8231387B2 (en) 2008-07-02 2012-07-31 Zimmer, Inc. Porous implant with non-porous threads
US9095396B2 (en) 2008-07-02 2015-08-04 Zimmer Dental, Inc. Porous implant with non-porous threads
US8899982B2 (en) 2008-07-02 2014-12-02 Zimmer Dental, Inc. Implant with structure for securing a porous portion
US8562348B2 (en) 2008-07-02 2013-10-22 Zimmer Dental, Inc. Modular implant with secured porous portion
US20100114314A1 (en) 2008-11-06 2010-05-06 Matthew Lomicka Expandable bone implant
US9707058B2 (en) * 2009-07-10 2017-07-18 Zimmer Dental, Inc. Patient-specific implants with improved osseointegration
US8602782B2 (en) 2009-11-24 2013-12-10 Zimmer Dental, Inc. Porous implant device with improved core
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
US9131995B2 (en) 2012-03-20 2015-09-15 Biomet 3I, Llc Surface treatment for an implant surface
DE102012021003B4 (de) 2012-10-26 2015-02-12 Otto Bock Healthcare Products Gmbh Perkutanes lmplantat und Verfahren zum Herstellen eines solchen lmplantates
RU2524764C1 (ru) * 2013-02-28 2014-08-10 Дмитрий Константинович Юдин Способ получения дентального имплантата погружного типа из титана или титанового сплава и дентальный имплантат из титана или титанового сплава
MX339086B (es) 2013-06-20 2016-05-09 Inmolecule Internat Ltd Nanomaterial de dioxido de titanio nanoparticulado modificado con grupos funcionales y con extractos citricos adsorbidos en la superficie para la eliminacion de amplio espectro de microorganismos.
RU2630578C1 (ru) * 2016-10-31 2017-09-11 федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский национальный исследовательский политехнический университет" Способ модифицирования поверхности титановых имплантатов
US10537661B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same
US10537658B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same
CN107397977B (zh) * 2017-08-03 2021-01-26 广东工业大学 3d打印金属基体表面改性的方法、3d打印金属基生物陶瓷支架及其制备方法
RU2687792C1 (ru) * 2018-05-07 2019-05-16 Сергей Вячеславович Купряхин Способ изготовления внутрикостного имплантата
KR102286394B1 (ko) * 2020-11-24 2021-08-06 주식회사 오스메딕 생체용 재료의 수산화인회석 코팅방법 및 이를 이용하여 제조된 수산화인회석이 코팅된 생체용 재료

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1026555C (zh) * 1986-05-15 1994-11-16 住友胶接剂株式会社 人工生体复合材料
US4737411A (en) * 1986-11-25 1988-04-12 University Of Dayton Controlled pore size ceramics particularly for orthopaedic and dental applications
SE464911B (sv) * 1988-01-20 1991-07-01 Inst Applied Biotechnology Anti-inflammatoriskt medel, baserat paa reaktionsprodukten mellan h?712o?712 och titan, foerfarande foer dess framstaellning samt anvaendning daerav
US5152993A (en) * 1988-01-20 1992-10-06 Ellem Bioteknik Ab Method of preparing an implant body for implantation
SE464850B (sv) * 1989-07-19 1991-06-24 Ellem Bioteknik Ab Saett foer preparering av en implantatkropp genom behandling med en vaeteperoxidloesning
US5032552A (en) * 1988-07-04 1991-07-16 Tdk Corporation Biomedical material

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999066966A1 (fr) * 1998-06-22 1999-12-29 Anatoly Dosta Revetement de type film fin pour implant osseux

Also Published As

Publication number Publication date
WO1993021969A1 (en) 1993-11-11
DE69322779T2 (de) 1999-05-20
EP0642362B1 (en) 1998-12-23
RU2124329C1 (ru) 1999-01-10
KR100263555B1 (ru) 2001-11-22
EP0642362A1 (en) 1995-03-15
FI921802L (fi) 1993-10-24
ATE174803T1 (de) 1999-01-15
ES2125979T3 (es) 1999-03-16
DE69322779D1 (de) 1999-02-04
GR3029407T3 (en) 1999-05-28
KR950700764A (ko) 1995-02-20
CA2118036A1 (en) 1993-11-11
US5612049A (en) 1997-03-18
CA2118036C (en) 2005-02-15
AU3954793A (en) 1993-11-29
JP3220150B2 (ja) 2001-10-22
DK0642362T3 (da) 1999-08-23
FI91713C (fi) 1994-08-10
FI91713B (fi) 1994-04-29
FI921802A0 (fi) 1992-04-23
AU672198B2 (en) 1996-09-26
JPH07505809A (ja) 1995-06-29

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