RU94038050A - Рекомбинантный вирус, вектор, вакцина, способ иммунизации, клетка-хозяин - Google Patents
Рекомбинантный вирус, вектор, вакцина, способ иммунизации, клетка-хозяинInfo
- Publication number
- RU94038050A RU94038050A RU94038050/13A RU94038050A RU94038050A RU 94038050 A RU94038050 A RU 94038050A RU 94038050/13 A RU94038050/13 A RU 94038050/13A RU 94038050 A RU94038050 A RU 94038050A RU 94038050 A RU94038050 A RU 94038050A
- Authority
- RU
- Russia
- Prior art keywords
- virus
- swine pox
- vaccine
- recombinant
- vector
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title claims abstract 6
- 239000013598 vector Substances 0.000 title claims abstract 4
- 230000003053 immunization Effects 0.000 title 1
- 238000002649 immunization Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 108020004414 DNA Proteins 0.000 claims abstract 5
- 241000282898 Sus scrofa Species 0.000 claims abstract 4
- 241000700565 Swinepox virus Species 0.000 claims abstract 4
- 108020005202 Viral DNA Proteins 0.000 claims abstract 2
- 230000010076 replication Effects 0.000 claims abstract 2
- 241000700647 Variola virus Species 0.000 claims 2
- 235000015277 pork Nutrition 0.000 claims 1
- 230000003362 replicative effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000029812 viral genome replication Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Изобретение относится к способному реплицироваться рекомбинантному вирусу свиной оспы, содержащему чужеродную ДНК, вставленную в участок вирусной ДНК свиной оспы, не имеющий существенного значения для репликации вируса свиной оспы. Кроме того, изобретение относится к гомологичным векторам, продуцирующим рекомбинантные вирусы свиной оспы путем вставки чужеродной ДНК в вирусную ДНК свиной оспы.
Claims (1)
- Изобретение относится к способному реплицироваться рекомбинантному вирусу свиной оспы, содержащему чужеродную ДНК, вставленную в участок вирусной ДНК свиной оспы, не имеющий существенного значения для репликации вируса свиной оспы. Кроме того, изобретение относится к гомологичным векторам, продуцирующим рекомбинантные вирусы свиной оспы путем вставки чужеродной ДНК в вирусную ДНК свиной оспы.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/820,154 US5382425A (en) | 1992-01-13 | 1992-01-13 | Recombinant swinepox virus |
US07/820,154 | 1992-01-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
RU94038050A true RU94038050A (ru) | 1996-05-10 |
Family
ID=25230024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU94038050/13A RU94038050A (ru) | 1992-01-13 | 1993-01-13 | Рекомбинантный вирус, вектор, вакцина, способ иммунизации, клетка-хозяин |
Country Status (13)
Country | Link |
---|---|
US (1) | US5382425A (ru) |
EP (1) | EP0677114B1 (ru) |
JP (1) | JP3527240B2 (ru) |
AT (1) | ATE236262T1 (ru) |
AU (1) | AU675216B2 (ru) |
CA (1) | CA2127541C (ru) |
DE (1) | DE69332831T2 (ru) |
DK (1) | DK0677114T3 (ru) |
ES (1) | ES2191663T3 (ru) |
NZ (1) | NZ249278A (ru) |
PT (1) | PT677114E (ru) |
RU (1) | RU94038050A (ru) |
WO (1) | WO1993014194A1 (ru) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2528750C2 (ru) * | 2008-11-19 | 2014-09-20 | Лабораторио Ави-Мекс, С.А. Де С.В. | Рекомбинантная вакцина на основе инактивированного вирусного вектора |
RU2560420C2 (ru) * | 2009-06-25 | 2015-08-20 | МЕДИММЬЮН, ЭлЭлСи | Варианты гемагглютининов вируса свиного гриппа |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5651972A (en) | 1989-04-21 | 1997-07-29 | University Of Florida Research Foundation, Inc. | Use of recombinant swine poxvirus as a live vaccine vector |
US6497882B1 (en) * | 1992-01-13 | 2002-12-24 | Syntro Corporation | Recombinant swinepox virus |
US5869312A (en) * | 1992-01-13 | 1999-02-09 | Syntro Corporation | Recombinant swinepox virus |
US6127163A (en) * | 1992-01-13 | 2000-10-03 | Syntro Corporation | Recombinant swinepox virus |
EP0617478B1 (en) * | 1993-03-25 | 1998-07-29 | Matsushita Electric Industrial Co., Ltd. | Laminated dielectric resonator and dielectric filter |
US6875856B2 (en) | 1993-09-24 | 2005-04-05 | Syntro Corporation | Recombinant infectious laryngotracheitis virus and uses thereof |
US5698394A (en) * | 1994-06-01 | 1997-12-16 | Board Of Regents Of The University Of Nebraska | Nucleotide sequences and methods for detection of Serpulina hyodysenteriae |
AU755763B2 (en) * | 1995-01-19 | 2002-12-19 | Syntro Corporation | Recombinant swinepox virus |
EP0801678A4 (en) * | 1995-01-19 | 2003-05-02 | Syntro Corp | RECOMBINED PIGBACK VIRUS |
US6221361B1 (en) * | 1995-01-19 | 2001-04-24 | Syntro Corporation | Recombinant swinepox virus |
WO1998004727A1 (en) * | 1996-07-25 | 1998-02-05 | Therion Biologics Corporation | Recombinant pox virus for immunization against tumor-associated antigens |
WO1998020899A1 (en) * | 1996-11-12 | 1998-05-22 | Board Of Regents University Of Nebraska Lincoln | Attenuated serpulina hyodysenteriae mutant for prevention of swine dysentery |
US6517843B1 (en) | 1999-08-31 | 2003-02-11 | Merial | Reduction of porcine circovirus-2 viral load with inactivated PCV-2 |
FR2772047B1 (fr) * | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
US6497883B1 (en) | 1999-06-10 | 2002-12-24 | Merial | Porcine circovirus recombinant poxvirus vaccine |
ES2170622B1 (es) * | 1999-12-03 | 2004-05-16 | Consejo Superior De Investigaciones Cientificas | Clones y vectores infectivos derivados de coronavirus y sus aplicaciones. |
FR2823222B1 (fr) | 2001-04-06 | 2004-02-06 | Merial Sas | Vaccin contre le virus de la fievre du nil |
WO2003100007A2 (en) | 2002-05-24 | 2003-12-04 | Schering-Plough Ltd. | Eta-1 gene and methods for use |
US7468273B2 (en) | 2003-05-01 | 2008-12-23 | Meial Limited | Canine GHRH gene, polypeptides and methods of use |
DE602004029940D1 (de) * | 2003-12-08 | 2010-12-16 | Univ Loma Linda | Verfahren zum Nachweis von Pockenviren |
PT1881845E (pt) | 2005-04-25 | 2010-05-31 | Merial Ltd | Vacinas de vírus nipah |
US20080241184A1 (en) | 2005-08-25 | 2008-10-02 | Jules Maarten Minke | Canine influenza vaccines |
US7771995B2 (en) | 2005-11-14 | 2010-08-10 | Merial Limited | Plasmid encoding human BMP-7 |
EP1951751B1 (en) | 2005-11-14 | 2017-11-01 | Merial, Inc. | Gene therapy for renal failure |
US7862821B2 (en) | 2006-06-01 | 2011-01-04 | Merial Limited | Recombinant vaccine against bluetongue virus |
US7794714B2 (en) * | 2008-03-14 | 2010-09-14 | The United States Of America As Represented By The Secretary Of Agriculture | Newcastle disease virus monoclonal antibodies |
AR078253A1 (es) | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
AR083533A1 (es) | 2010-10-22 | 2013-03-06 | Boehringer Ingelheim Vetmed | Proteinas de hemaglutinina 5 (h5) para el tratamiento y prevencion de las infecciones de gripe |
AU2012245395A1 (en) | 2011-04-20 | 2013-11-14 | Merial, Inc. | Adjuvanted rabies vaccine with improved viscosity profile |
WO2012166493A1 (en) | 2011-06-01 | 2012-12-06 | Merial Limited | Needle-free administration of prrsv vaccines |
ES2626297T3 (es) | 2011-08-12 | 2017-07-24 | Merial, Inc. | Preservación asistida por vacío de productos biológicos, en particular de vacunas |
CA2925281C (en) | 2013-09-25 | 2022-05-03 | Zoetis Services Llc | Pcv2b divergent vaccine composition and methods of use |
CN112316129B (zh) | 2014-04-03 | 2025-01-28 | 勃林格殷格翰动物保健美国有限公司 | 猪流行性腹泻病毒疫苗 |
WO2016073410A1 (en) | 2014-11-03 | 2016-05-12 | Merial, Inc. | Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01503675A (ja) * | 1986-09-08 | 1989-12-14 | アプライド・バイオテクノロジー・インコーポレーテツド | 中空ウイルスキヤプシドのワクチン |
EP0261940A3 (en) * | 1986-09-23 | 1989-07-05 | Applied Biotechnology, Inc. | Pseudorabies vaccines and dna vectors for recombination with pox viruses |
WO1989010965A2 (en) * | 1988-05-03 | 1989-11-16 | The Upjohn Company | Glycoprotein h of herpes viruses |
US5225336A (en) * | 1989-03-08 | 1993-07-06 | Health Research Incorporated | Recombinant poxvirus host range selection system |
-
1992
- 1992-01-13 US US07/820,154 patent/US5382425A/en not_active Expired - Lifetime
-
1993
- 1993-01-13 DE DE69332831T patent/DE69332831T2/de not_active Expired - Lifetime
- 1993-01-13 DK DK93904494T patent/DK0677114T3/da active
- 1993-01-13 NZ NZ249278A patent/NZ249278A/en not_active IP Right Cessation
- 1993-01-13 AU AU35830/93A patent/AU675216B2/en not_active Expired
- 1993-01-13 WO PCT/US1993/000324 patent/WO1993014194A1/en active IP Right Grant
- 1993-01-13 RU RU94038050/13A patent/RU94038050A/ru unknown
- 1993-01-13 EP EP93904494A patent/EP0677114B1/en not_active Expired - Lifetime
- 1993-01-13 CA CA002127541A patent/CA2127541C/en not_active Expired - Lifetime
- 1993-01-13 AT AT93904494T patent/ATE236262T1/de not_active IP Right Cessation
- 1993-01-13 PT PT93904494T patent/PT677114E/pt unknown
- 1993-01-13 JP JP51265693A patent/JP3527240B2/ja not_active Expired - Lifetime
- 1993-01-13 ES ES93904494T patent/ES2191663T3/es not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2528750C2 (ru) * | 2008-11-19 | 2014-09-20 | Лабораторио Ави-Мекс, С.А. Де С.В. | Рекомбинантная вакцина на основе инактивированного вирусного вектора |
RU2560420C2 (ru) * | 2009-06-25 | 2015-08-20 | МЕДИММЬЮН, ЭлЭлСи | Варианты гемагглютининов вируса свиного гриппа |
Also Published As
Publication number | Publication date |
---|---|
DE69332831D1 (de) | 2003-05-08 |
EP0677114A1 (en) | 1995-10-18 |
CA2127541C (en) | 2005-03-22 |
NZ249278A (en) | 1996-05-28 |
ES2191663T3 (es) | 2003-09-16 |
AU675216B2 (en) | 1997-01-30 |
AU3583093A (en) | 1993-08-03 |
ATE236262T1 (de) | 2003-04-15 |
JPH07506481A (ja) | 1995-07-20 |
DE69332831T2 (de) | 2004-01-29 |
CA2127541A1 (en) | 1993-07-22 |
PT677114E (pt) | 2003-07-31 |
EP0677114B1 (en) | 2003-04-02 |
JP3527240B2 (ja) | 2004-05-17 |
WO1993014194A1 (en) | 1993-07-22 |
DK0677114T3 (da) | 2003-04-22 |
US5382425A (en) | 1995-01-17 |
EP0677114A4 (en) | 1995-07-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU94038050A (ru) | Рекомбинантный вирус, вектор, вакцина, способ иммунизации, клетка-хозяин | |
EE200300332A (et) | Rekombinantne MVA viirus ja selle kasutamine, isoleeritud eukarüootne rakk, meetod rekombinantse hTyr-proteiini valmistamiseks ning vaktsiin | |
CY1116761T1 (el) | Αλληλουχιες κυκλοϊου σχετικου με την νοσο απισχνασης του χοιριδιου (map) | |
BR9712592A (pt) | Processo para gerar um clone infeccioso, ácido nucléico recombinante, molécula do mesmo, vìrus de rna modificado, célula infectada com o mesmo, vacina, proteìna e/ou antìgeno, e, ensaio diagnóstico | |
BG102712A (en) | Mixture of recombinant vaccinia vectors as polyenv-vaccines against hiv | |
DK1253201T3 (da) | Kyllingeanæmivirusmutanter og vacciner baseret på det virale protein VP3 eller sekvenser af dette virus kodende derfor | |
DK0831899T3 (da) | Rekombinant koppevirus-calicivirus-præparater og anvendelser | |
NO942075L (no) | Rekombinante virus omfattende kunstig proteolytisk spaltingssete | |
NO902491D0 (no) | Proteiner, vaksiner og nukleinsyrer. | |
Drillien | Vaccinia virus as an expression vector | |
MY157873A (en) | Recombinant mva virus, and the use thereof | |
MY134484A (en) | Recombinant mva virus, and the use thereof | |
MY119381A (en) | Recombinant mva virus, and the use thereof |