[go: up one dir, main page]

RU93047920A - Substituted - Google Patents

Substituted

Info

Publication number
RU93047920A
RU93047920A RU93047920/04A RU93047920A RU93047920A RU 93047920 A RU93047920 A RU 93047920A RU 93047920/04 A RU93047920/04 A RU 93047920/04A RU 93047920 A RU93047920 A RU 93047920A RU 93047920 A RU93047920 A RU 93047920A
Authority
RU
Russia
Prior art keywords
substituted
benzisoxazoles
pyridinylamino
thiophenes
antidepressants
Prior art date
Application number
RU93047920/04A
Other languages
Russian (ru)
Other versions
RU2083575C1 (en
Inventor
С.Эффланд Ричард
Т.Клейн Джозеф
Л.Мартин Лоуренс
М. Шацке Грегори
Дж. Кэпплз Кевин
Д.Томер Джон IV
S.Ehffland Richard
T.Klejn Dzhozef
L.Martin Lourens
M. Shatske Gregori
Dzh. Kehpplz Kevin
D.Tomer Dzhon IV
Original Assignee
Хехст-Рассел Фармасьютикалз Инкорпорейтед
Khekhst-Rassel Farmas'jutikalz Inkorporejted
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/964,546 external-priority patent/US5328920A/en
Application filed by Хехст-Рассел Фармасьютикалз Инкорпорейтед, Khekhst-Rassel Farmas'jutikalz Inkorporejted filed Critical Хехст-Рассел Фармасьютикалз Инкорпорейтед
Publication of RU93047920A publication Critical patent/RU93047920A/en
Application granted granted Critical
Publication of RU2083575C1 publication Critical patent/RU2083575C1/en

Links

Claims (1)

Замещенные (пиридиниламино)-бензизоксазолы и -бензо[р]тиофены, способ их получения и их использование в качестве лекарственных средств. Описываются различные соединения, имеющие формулу, представленную ниже,
Figure 00000001
где R<Mv>1<D>, W, X, Y и Z имеют значения, определенные в описании, которые являются используемыми в качестве антидепрессантов.Substituted (pyridinylamino) -benzisoxazoles and -benzo [p] thiophenes, method for their preparing and their use as pharmaceuticals Describes the various compounds having the formula below,
Figure 00000001
where R <Mv> 1 <D>, W, X, Y and Z have the meanings defined in the description, which are used as antidepressants.
RU9393047920A 1992-10-21 1993-10-20 Substituted (pyridinylamino)-benzisoxazoles or their pharmaceutically acceptable acid-additive salts and a method of their synthesis RU2083575C1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/964,546 US5328920A (en) 1991-04-17 1992-10-21 Substituted (pyridinylamino)-indoles
US07/964.546 1992-10-21

Publications (2)

Publication Number Publication Date
RU93047920A true RU93047920A (en) 1996-08-10
RU2083575C1 RU2083575C1 (en) 1997-07-10

Family

ID=25508677

Family Applications (1)

Application Number Title Priority Date Filing Date
RU9393047920A RU2083575C1 (en) 1992-10-21 1993-10-20 Substituted (pyridinylamino)-benzisoxazoles or their pharmaceutically acceptable acid-additive salts and a method of their synthesis

Country Status (18)

Country Link
US (1) US5328920A (en)
EP (1) EP0594000B1 (en)
KR (1) KR100297651B1 (en)
AT (1) ATE168689T1 (en)
AU (1) AU665637B2 (en)
CA (1) CA2108800A1 (en)
DE (1) DE69319830T2 (en)
DK (1) DK0594000T3 (en)
ES (1) ES2120463T3 (en)
FI (1) FI934611L (en)
GR (1) GR3027574T3 (en)
HU (1) HUT68875A (en)
IL (1) IL107330A (en)
NO (1) NO300806B1 (en)
NZ (1) NZ248991A (en)
PL (1) PL173540B1 (en)
RU (1) RU2083575C1 (en)
ZA (1) ZA937823B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039397A1 (en) * 1995-06-06 1996-12-12 Hoechst Marion Roussel, Inc. Benzisoxazole and indazole derivatives as antipsychotic agents
US5668154A (en) * 1995-06-06 1997-09-16 Hoechst Marion Roussel Inc. Pyridiniminyl-1,2-benzisoxazoles and -benzisothiazoles
GB2308362A (en) * 1995-12-19 1997-06-25 Lilly Industries Ltd Pharmaceutical indole derivatives
CA2276203C (en) * 1996-12-27 2003-07-22 Hoechst Marion Roussel, Inc. N-(pyridinylamino)isoindolines and related compounds
US5886191A (en) * 1997-08-18 1999-03-23 Dupont Pharmaceuticals Company Amidinoindoles, amidinoazoles, and analogs thereof
US7091199B1 (en) 1999-09-14 2006-08-15 Aventis Pharmaceuticals Inc. Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists
US7125903B1 (en) 1999-09-14 2006-10-24 Aventis Pharmaceuticals Inc. Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists
US7253165B2 (en) * 1999-09-14 2007-08-07 Aventis Pharmaceuticals Inc. Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists
US20020161002A1 (en) * 2001-01-02 2002-10-31 Mel Epstein Use of catecholamine reuptake inhibitors to enhance memory
DE60313769T2 (en) * 2002-04-23 2008-03-06 Aventis Pharmaceuticals Inc. 3- (PYRIDINYL-AMINO) -1H-INDOL-2-CARBOXYLIC COMPOUNDS AS INHIBITORS OF INTERLEUKIN-4 GENE EXPRESSION
GB0217920D0 (en) * 2002-04-23 2002-09-11 Aventis Pharm Prod Inc Interleukin-4 Gene Expression inhibitors
DE102005038947A1 (en) * 2005-05-18 2006-11-30 Grünenthal GmbH Substituted benzo [d] isoxazol-3-yl-amine compounds and their use in medicaments
MX2009001875A (en) * 2006-08-21 2009-03-02 Genentech Inc Aza-benzothiophenyl compounds and methods of use.
EP2069354B1 (en) * 2006-08-21 2011-11-02 Genentech, Inc. Aza-benzofuranyl compounds and methods of use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3166987D1 (en) * 1980-09-18 1984-12-06 Asahi Chemical Ind 3-aminoindazole derivatives and process for preparation thereof
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4717658A (en) * 1985-12-03 1988-01-05 Miles Inc. Gram negative bacteria screening method with horseshoe crab amebocyte lysate (LAL)
DE3852335T2 (en) * 1987-04-24 1995-05-11 Hoechst Roussel Pharma N- (Pyridinyl) -1H-indol-1-amines, process for their preparation and their use as medicaments.
US4954502A (en) * 1988-06-10 1990-09-04 Bristol-Myers Squibb Company 1-indolyalkyl-4-(substituted-pyridinyl)piperazines
DE69021645T2 (en) * 1989-05-19 1996-02-22 Hoechst-Roussel Pharmaceuticals Inc., Somerville, N.J. N- (aryloxyalkyl) heteroarylpiperidines and heteroarylpiperazines, processes for their preparation and their use as medicaments.
US4954503A (en) * 1989-09-11 1990-09-04 Hoechst-Roussel Pharmaceuticals, Inc. 3-(1-substituted-4-piperazinyl)-1H-indazoles
CA2030051C (en) * 1989-11-17 2001-08-07 Haruhiko Kikuchi Indole derivatives
US5177088A (en) * 1991-04-17 1993-01-05 Hoechst-Roussel Pharmaceuticals Incorporated Substituted 3-(pyridinylamino)-indoles

Similar Documents

Publication Publication Date Title
RU93048636A (en) 7- / SUBSTITUTED / -8- / SUBSTITUTED / -9- / SUBSTITUTED AMINO / -6-DIMETHYL-6-DEOXYTETRACYCLINES, INTERMEDIATE COMPOUNDS, METHODS FOR PRODUCING COMPOUNDS, METHOD FOR PREVENTION AND TREATMENT
RU93042100A (en) NEW 7- (SUBSTITUTED) -8- (SUBSTITUTED) -9 - [(SUBSTITUTED GLYCYL) AMIDO] -6-DEMETHYL-6-DEOXYTETRICINE
RU93047920A (en) Substituted
RU93055882A (en) DERIVATIVES OF N-SULFONIL-2-OXOINDOL, METHOD FOR PRODUCING THEM, ORIGINAL FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITION ON THEIR BASIS
DE69005394D1 (en) COMPOSITIONS WHICH COMPLEXES CONTAIN HYALURONIC ACID AND METHOD FOR THE PRODUCTION THEREOF.
RU92004593A (en) HETEROCYCLYLMETHYL-CHROMAN DERIVATIVES IN THE FORM OF A MIXTURE OF ISOMERS OR SEPARATE ISOMERS OR THEIR SALTS, METHOD FOR PRODUCING THEM AND MEDICINE
DE69002795D1 (en) STABILIZED AGENTS CONTAINING THE EPIDERMAL GROWTH FACTOR.
RU93041055A (en) NEW 4-ARYLPIPERAZINES AND 4-ARYLPIPERIDINES
EP0369262A3 (en) Novel pyrroles
ATE90088T1 (en) 1-CHLOROPYRIMIDINYL-1H-1,2,4-TRIAZOLE-3SULPHONE|UREAMIDE, PROCESS FOR THEIR PREPARATION AND USE AS HERBICIDAL AGENT.
RU93005256A (en) DERIVATIVES OF CYCLOPEPTANE AND PENTEN-β-AMINO ACIDS AND THEIR SALTS, METHOD FOR PRODUCING THEM AND ANTIBACTERIAL MEANS
RU93005029A (en) TRICYCLIC COMPOUNDS CONTAINING HETEROATOMS
RU92004359A (en) HYDRAZONES
DE59005898D1 (en) Disodium salt of trimercapto-s-triazine hexahydrate, process for its preparation and use.
IT1252180B (en) 5,5 &#39;- (1,3-PROPANDIIL) BIS (IMINO (2-BONE-2,1-ETANDIIL) ACETYLIMINE) -BIS (2,4,6-TRIIODE-1,3-BENZENDICARBOXY), THEIR METHOD OF PREPARATION AND ROENTGENOGRAPHIC CONTRAST MEANS THAT CONTAIN THEM
EP0234348A3 (en) N-glycosyl amide derivatives, method for their preparation and their use as medicaments
ITRM930764A0 (en) PROCEDURE FOR THE PREPARATION OF WATER-SOLUBLE SULFUR DYES. (CASE150-5689)
DE69016587D1 (en) Process for the preparation of 5-amino-3-chlorosulfonyl-1,2,4-triazole.
DE59001431D1 (en) 1-METHOXYPYRIMIDINYL-1H-1,2,4-TRIAZOL-3-SULFONE ACIDITROANILIDE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AN AGENT WITH HERBICIDAL ACTIVITY.
EP0433749A3 (en) Pyrazolin-5-on-derivatives
PH24990A (en) 1-(1 aryl-2-hydroxyethyl)-imidazoles and salts thereof
DE69112987D1 (en) Polyhalophthalocyanines, process for their preparation and their use.
EP0457723A3 (en) Method for the stabilization of magenta couplers and the resulting dye-images in photographic materials
ES2021944A6 (en) New derivatives of 1,3,5-triamino-2,4,6-triiodobenzene and method for the preparation thereof
IT9022507A0 (en) PROCEDURE FOR THE PREPARATION OF N-(26AMMINO63,5-DIBROMO-BENZYL)-TRANS-4-AMINOCYCLOHEXANOL3.