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RU93013167A - METHOD FOR PRODUCING 6-OXA-8-ISOANALOGUES OF STEROID ESTROGENES - Google Patents

METHOD FOR PRODUCING 6-OXA-8-ISOANALOGUES OF STEROID ESTROGENES

Info

Publication number
RU93013167A
RU93013167A RU93013167/04A RU93013167A RU93013167A RU 93013167 A RU93013167 A RU 93013167A RU 93013167/04 A RU93013167/04 A RU 93013167/04A RU 93013167 A RU93013167 A RU 93013167A RU 93013167 A RU93013167 A RU 93013167A
Authority
RU
Russia
Prior art keywords
oxa
isoanalogues
estrogenes
steroid
producing
Prior art date
Application number
RU93013167/04A
Other languages
Russian (ru)
Other versions
RU2057140C1 (en
Inventor
А.Г. Шавва
И.В. Ищенко
И.И. Елисеев
Ш.Н. Абусалимов
Э.Г. Гаспарян
Original Assignee
А.Г. Шавва
И.В. Ищенко
И.И. Елисеев
Ш.Н. Абусалимов
Э.Г. Гаспарян
Filing date
Publication date
Application filed by А.Г. Шавва, И.В. Ищенко, И.И. Елисеев, Ш.Н. Абусалимов, Э.Г. Гаспарян filed Critical А.Г. Шавва
Priority to RU93013167A priority Critical patent/RU2057140C1/en
Priority claimed from RU93013167A external-priority patent/RU2057140C1/en
Application granted granted Critical
Publication of RU2057140C1 publication Critical patent/RU2057140C1/en
Publication of RU93013167A publication Critical patent/RU93013167A/en

Links

Claims (1)

Каталитическое гидрирование 6-окса-1,3,5(10),8,14- экстрапентаенов на никеле Ренея в бензоле при 80 - 110oС и давлении 10 - 15 МПа протекает стереоселективно и приводит к образованию соединений 8-изоряда с существенно более высоким выходом, чем при использовании палладиевых катализаторов.The catalytic hydrogenation of 6-oxa-1,3,5 (10), 8,14-extrapentaenes on Raney nickel in benzene at 80 - 110 o C and a pressure of 10 - 15 MPa occurs stereoselectively and leads to the formation of 8-isoride compounds with significantly more higher yield than with palladium catalysts.
RU93013167A 1993-03-12 1993-03-12 Method of synthesis of 6-oxa-8-isoanalogs of steroid estrogens RU2057140C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU93013167A RU2057140C1 (en) 1993-03-12 1993-03-12 Method of synthesis of 6-oxa-8-isoanalogs of steroid estrogens

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU93013167A RU2057140C1 (en) 1993-03-12 1993-03-12 Method of synthesis of 6-oxa-8-isoanalogs of steroid estrogens

Publications (2)

Publication Number Publication Date
RU2057140C1 RU2057140C1 (en) 1996-03-27
RU93013167A true RU93013167A (en) 1997-01-10

Family

ID=20138585

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93013167A RU2057140C1 (en) 1993-03-12 1993-03-12 Method of synthesis of 6-oxa-8-isoanalogs of steroid estrogens

Country Status (1)

Country Link
RU (1) RU2057140C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2679625C1 (en) * 2018-11-08 2019-02-12 Ильясов Шамиль Сионович 3-o-sulfamoiloxy-6-oxa-7β-methyl-d-homo-8α-estra-1,3,5(10)-trien-17α-one application for the breast cancer treatment, including the triple negative form, and its production method

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