[go: up one dir, main page]

RU92016453A - HYDROXAMIC ACIDS AND N-HYDROXYMOCHUMEN, WAYS OF THEIR RECOVERY, PHARMACEUTICAL COMPOSITION AND METHOD OF INHIBITING LIPOXYGENASE - Google Patents

HYDROXAMIC ACIDS AND N-HYDROXYMOCHUMEN, WAYS OF THEIR RECOVERY, PHARMACEUTICAL COMPOSITION AND METHOD OF INHIBITING LIPOXYGENASE

Info

Publication number
RU92016453A
RU92016453A RU92016453/04A RU92016453A RU92016453A RU 92016453 A RU92016453 A RU 92016453A RU 92016453/04 A RU92016453/04 A RU 92016453/04A RU 92016453 A RU92016453 A RU 92016453A RU 92016453 A RU92016453 A RU 92016453A
Authority
RU
Russia
Prior art keywords
hydroxymochumen
recovery
ways
pharmaceutical composition
hydroxamic acids
Prior art date
Application number
RU92016453/04A
Other languages
Russian (ru)
Other versions
RU2108324C1 (en
Inventor
Уилльям Стивенс Родни
Икеда Такафуми
Вакабайяси Хироаки
Накане Масами
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Priority claimed from PCT/US1991/002674 external-priority patent/WO1991016298A1/en
Publication of RU92016453A publication Critical patent/RU92016453A/en
Application granted granted Critical
Publication of RU2108324C1 publication Critical patent/RU2108324C1/en

Links

Claims (1)

Описываются соединения, имеющие структуру
Figure 00000001

где X представляет азот, кислород, серу или связь, и Z представляет кислород или серу. Эти соединения являются ингибиторами липоксигеназы и полезны в качестве активных агентов в фармацевтических композициях для лечения воспалительных состояний людей и других млекопитающих, причиной которых является активность липоксигеназы.Describes compounds having the structure
Figure 00000001

where X represents nitrogen, oxygen, sulfur or a bond, and Z represents oxygen or sulfur. These compounds are lipoxygenase inhibitors and are useful as active agents in pharmaceutical compositions for the treatment of inflammatory conditions in humans and other mammals caused by lipoxygenase activity.
RU92016453A 1990-04-20 1991-04-18 Hydroxamic acid and hydroxyurea derivatives and methods of their synthesis RU2108324C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10504890 1990-04-20
JP105048/90 1990-04-20
PCT/US1991/002674 WO1991016298A1 (en) 1990-04-20 1991-04-18 Antiinflammatory hydroxamic acids and n-hydroxyureas

Publications (2)

Publication Number Publication Date
RU92016453A true RU92016453A (en) 1995-03-27
RU2108324C1 RU2108324C1 (en) 1998-04-10

Family

ID=14397114

Family Applications (1)

Application Number Title Priority Date Filing Date
RU92016453A RU2108324C1 (en) 1990-04-20 1991-04-18 Hydroxamic acid and hydroxyurea derivatives and methods of their synthesis

Country Status (29)

Country Link
US (1) US5256789A (en)
EP (1) EP0525111B1 (en)
JP (1) JPH075560B2 (en)
KR (1) KR900016822A (en)
CN (1) CN1033325C (en)
AT (1) ATE123764T1 (en)
AU (1) AU646865B2 (en)
BR (1) BR9106367A (en)
CA (1) CA2078216A1 (en)
CS (1) CS110491A3 (en)
DE (1) DE69110460T2 (en)
DK (1) DK0525111T3 (en)
EG (1) EG19608A (en)
ES (1) ES2073755T3 (en)
FI (1) FI924725A7 (en)
GR (1) GR3017078T3 (en)
HU (1) HUT61723A (en)
IE (1) IE66530B1 (en)
IL (1) IL97866A (en)
MY (1) MY106510A (en)
NO (1) NO180482C (en)
NZ (1) NZ237884A (en)
PL (1) PL165843B1 (en)
PT (1) PT97422A (en)
RU (1) RU2108324C1 (en)
TW (1) TW206221B (en)
WO (1) WO1991016298A1 (en)
YU (1) YU48329B (en)
ZA (1) ZA912935B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9002375D0 (en) * 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
CA2078126A1 (en) * 1990-03-27 1991-09-28 Jerry Leroy Adams 5-lipoxygenase inhibitors
US5260316A (en) * 1991-07-30 1993-11-09 Ciba-Geigy Corporation Isoquinolyl substituted hydroxylamine derivatives
US5350761A (en) * 1991-07-30 1994-09-27 Ciba-Geigy Corporation Indolyl substituted hydroxylamine derivatives
US5334600A (en) * 1991-07-30 1994-08-02 Ciba-Geigy Corporation Isoquinolyl substituted hydroxylamine derivatives
CA2132831C (en) * 1992-04-07 1998-06-16 J. Martin Grisar Hydrazide derivatives of 3,4-dihydro-2h-1-benzopyrans
JP2661841B2 (en) * 1992-07-23 1997-10-08 ファイザー製薬株式会社 Indoline derivatives
US6225351B1 (en) 1995-07-26 2001-05-01 Pfizer Inc. N-(aroyl) glycine hydroxamic acid derivatives and related compounds
HUP0104421A3 (en) * 1998-12-14 2003-05-28 Hoffmann La Roche Phenylglycine derivatives
WO2001087834A1 (en) * 2000-05-16 2001-11-22 Takeda Chemical Industries, Ltd. Melanin-concentrating hormone antagonist
CN101437524B (en) * 2004-09-14 2012-01-11 法莫赛特股份有限公司 Preparation of 2' ifluoro-2'- alkyl- substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
EP1807080A1 (en) * 2004-10-29 2007-07-18 AstraZeneca AB Use of unsaturated quionoline or naphtalene derivatives as medicaments
FR2881137B1 (en) * 2005-01-27 2007-03-02 Servier Lab NOVEL HETEROCYCLIC OXIMIC DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
ATE527998T1 (en) * 2005-08-03 2011-10-15 Univ California ILLUDIN ANALOGAS AS ANTI-CANCER MEDICINE
US8512464B2 (en) 2009-12-02 2013-08-20 3M Innovative Properties Company Functionalized zirconia nanoparticles and high index films made therefrom
AU2011255627A1 (en) * 2010-05-18 2012-12-06 Eastern Virginia Medical School Inhibitors of human 12-lipoxygenase
WO2012093100A1 (en) * 2011-01-05 2012-07-12 Syngenta Participations Ag Pyrazol-4-yl carboxamide derivatives as microbiocides
RU2720237C2 (en) 2013-11-18 2020-04-28 Форма Терапеутикс, Инк. Compositions containing benzopiperazine as bromodomain bet inhibitors
SI3071203T1 (en) 2013-11-18 2021-07-30 Forma Therapeutics, Inc. Tetrahydroquinoline compositions as bet bromodomain inhibitors
CA3022432A1 (en) * 2016-04-29 2017-11-02 Board Of Regents, The University Of Texas System Sigma receptor binders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE80611T1 (en) * 1985-03-16 1992-10-15 Wellcome Found ARYL DERIVATIVES.
US4728670A (en) * 1986-06-04 1988-03-01 E. R. Squibb & Sons, Inc. Biphenyl hydroxamic acids
DE3882732T2 (en) * 1987-02-10 1993-12-02 Abbott Lab Indole, benzofuran, benzothiophene-containing lipoxygenase inhibiting compounds.
US4897422A (en) * 1987-02-10 1990-01-30 Abbott Laboratories Lipoxygenase inhibiting compounds
CA1336099C (en) * 1987-04-24 1995-06-27 James B. Summers, Jr. Urea based lipoxygenase compounds
US4822809A (en) * 1987-11-13 1989-04-18 Abbott Laboratories Benzazole lipoxygenase inhibiting compounds
DK418289A (en) * 1989-08-24 1991-02-25 Micro Matic As ANTI-LASHING SECURITY SYSTEM

Similar Documents

Publication Publication Date Title
RU92016453A (en) HYDROXAMIC ACIDS AND N-HYDROXYMOCHUMEN, WAYS OF THEIR RECOVERY, PHARMACEUTICAL COMPOSITION AND METHOD OF INHIBITING LIPOXYGENASE
RU93004907A (en) Hydroxamic Acid Derivatives and N-Hydroxyurea. METHOD FOR PRODUCING THE PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT
DK0525111T3 (en) Anti-inflammatory hydroxamic acids and N-hydroxyureas
RU94017851A (en) INHIBITORS OF PROTEOLYTIC ENZYMES BASED ON SUCHARINE DERIVATIVES, A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DEGERATIVE DISEASES
RU93048636A (en) 7- / SUBSTITUTED / -8- / SUBSTITUTED / -9- / SUBSTITUTED AMINO / -6-DIMETHYL-6-DEOXYTETRACYCLINES, INTERMEDIATE COMPOUNDS, METHODS FOR PRODUCING COMPOUNDS, METHOD FOR PREVENTION AND TREATMENT
RU93036185A (en) DOUBLE ACTION INHIBITORS
TR199900431T2 (en) �kame edilmi� siklik amin metalloproteaz inhibit�rleri
EA199900876A1 (en) PHARMACEUTICAL COMPOSITIONS AGAINST COUGH
ATE227293T1 (en) 2,3-DISUBSTITUTED-(5,6)-HETEROARYL CONDENSED - PYRIMIDINE-4-ONE
RU2002123877A (en) Kahalalide compounds
KR920701213A (en) Methylenediphosphonic acid compound and anti-inflammatory agent using it as an active ingredient
DK166323C (en) GRISEOLIC ACID DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING THESE
RU94008619A (en) DERIVATIVES OF DIHYDROBENZOFURANE, HERBICID COMPOSITION AND METHOD FOR DESTROYING WEEDS
ES2146606T3 (en) METHOD FOR CLEANING CARPETS.
EA200100956A1 (en) PHARMACEUTICAL COMPOSITIONS BASED ON TIZOXANIDE AND NITAZOXANIDE
SE8303700D0 (en) THERAPEUTIC COMPOSITION
BG30616A3 (en) Fungicide means and method for fungus fighting
DD210597A1 (en) FUNGICIDAL AGENTS
EP0331105A3 (en) 1,2-hydroxy phosphonates and derivatives thereof
EP0334149A3 (en) Pyrimidinyl thionophosphoric-acid esters
RU94019328A (en) α- HETEROARILOXYMETYLKETONES, PHARMACEUTICAL COMPOSITION, INHIBITING INTERLEUKIN-1 - β-PROTEASIS
RU93046324A (en) 21-CHLOROPREGANAN DERIVATIVE, METHOD FOR ITS PREPARATION, PHARMACEUTICAL COMPOSITION ON ITS BASIS, METHOD FOR ITS PREPARATION
IT1184139B (en) MUCOLYTIC AND BRONCODILATORY ACTIVITY COMPOUNDS, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT AS ACTIVE INGREDIENTS
RU94013445A (en) NEW CONNECTION, LEISTRODUKSIN N, METHOD FOR ITS OBTAINING AND THERAPEUTIC COMPOSITION
RU93055680A (en) HIV PROTEASIS INHIBITORS, METHOD FOR PRODUCING, USE THEM, COMPOSITION