RU2598809C1 - Device for drug delivery - Google Patents

Abstract

FIELD: medical equipment.

SUBSTANCE: invention relates to medical equipment, particularly, to device for drug delivery and, in particular, to a device, equipped with security means for providing end user with information on state of said device. Drug delivery device comprises housing, drive mechanism starting element interlocking element and a display for displaying fact that device was used, provided by starting element which is held in its second position. Housing is configured to hold a vessel with drug with or without a connected delivery element. Drive mechanism is configured to be acted upon by vessel with drug and is configured to act on vessel with a drug. Starting element is configured to move from a first position, which enables it to retain drive mechanism, into a second position, in which it enables to release drive mechanism, in which there is possibility of displacement of drug through element for delivery. Interlocking element is configured to move between locking position, in which it prevents movement of starting element from its first position into a second position, and unlocking position at which is provided movement of starting element from its first position into second position. Starting element includes at least one fixing ledge. Drive mechanism includes corresponding fixing surfaces, relative to which fixing ledges are fixed, when starting element is in its second position.

EFFECT: invention fewer parts, is easy to use and prevents risk of use, or attempt to use, devices, which have already been used.

17 cl, 9 dwg

Description

FIELD OF TECHNOLOGY

The present invention relates to a device for the delivery of drugs and, in particular, to a device equipped with safety features to provide the target user with information about the status of the specified device.

BACKGROUND

Drug delivery devices for the automatic or semi-automatic injection of drugs have been known for many years. Despite the fact that injection devices of the first generations were created only for the fastest possible delivery of the drug, the wider use of these devices by patients outside the clinical conditions made it necessary to provide additional management and safety functions.

Important control and safety functions of drug delivery devices include prohibiting premature operation (misfire) of the device. In order to ensure that the drug is administered properly, the device is not allowed to operate until the automatic injection device is correctly located in the drug injection zone. In addition, since the drug delivery member may be sharp and contaminated after the device has been actuated, devices have been developed that retract or close the drug delivery member when the device is removed from the drug administration area. To prevent inadvertent contact of a person with the indicated element for drug delivery, as well as for the safe disposal of the device, some devices have a mechanism that blocks the device immediately after the element for drug delivery is closed or retracted.

Another important feature of drug delivery devices is to prevent the risk of using, or attempting to use, devices that have already been used, that is, ensuring that the target user is provided with information regarding the state of the device, as well as providing prohibitive properties after using the device for drug delivery funds. Many drug delivery devices are equipped with a kind of actuator, often including a start button or something similar. Such trigger buttons are often located at the distal end of the device, as far as possible from the drug administration area, so that the finger, often the thumb of the hand holding the device, can control the button. Such a construction is described in document EP 850079, which discloses a so-called syringe pen having a dose setting mechanism including a dose setting regulator from the distal end of the device. When the specified dose adjustment knob is rotated, the dose of the drug is set. In order to deliver the indicated dose, the dose adjustment knob, by pressing in the proximal direction, is brought to the final position in which it is axially locked. When it is necessary to deliver the next dose, the specified dose adjustment knob rotates again, thereby unlocking and shifting in the distal direction.

The device, in accordance with document EP 850079, is intended for repeated administration of drugs, therefore it is necessary that its dose setting regulator returns to its original position. Even if it is blocked after delivering a dose of the drug, the button is easily unlocked for the next dose. In the case of a device for drug delivery, designed for a single injection of the drug, the treatment of the specified device should not allow the possibility of returning the metering button. Then the user may get the impression that the device has not yet been used, and he may try to enter the dose of the drug using the used device. If a given user does not have access to another device for drug delivery, he may unexpectedly discover that he does not have delivery devices to implement the treatment regimen.

As shown above, commercially available drug delivery devices either do not provide the necessary control, security, and information functions, or they require interaction with one or more complex mechanisms. Accordingly, there is a need for drug delivery devices that include mechanisms that provide some or all of these functions in a reliable manner using as few parts as possible. This is especially important for single-use devices, in which case low production costs are a necessity.

SUMMARY OF THE INVENTION

In the present application, when the term "distal" is used, this refers to a direction pointing in the opposite direction from the drug administration zone. When using the term "distal part / distal end", this means the part / end of the delivery device, or parts / ends of its components, which are located as far as possible from the injection area of the drug.

Accordingly, when the term “proximal” is used, this refers to a direction pointing towards the drug administration zone. When using the term "proximal part / proximal end", this means the part / end of the delivery device, or the parts / ends of its components, which are located closest to the area of drug administration.

The aim of the present invention is to remedy the aforementioned disadvantages related to devices for the introduction of drugs of the prior art. This goal is achieved using a device for the administration of drugs, in accordance with the characteristics of the independent claims. Preferred embodiments of the present invention form the subject of the dependent claims.

In accordance with one preferred solution, the present invention relates to a device for drug delivery, including a housing adapted to accommodate a container with a drug. The specified container with the drug can have a number of designs and can have many sizes, depending on the intended use and type of drug. A suitable drug delivery element may be attached to said drug container. The specified item for delivery can be either an integral part of the specified container with a medicinal product, or be an attached item for delivery.

Additionally, said drug delivery element may have a number of designs, depending on the required functions and type of drug, such as nozzles, mouthpieces, inhalers, or injection needles, and these are few of the possible ones.

The drug delivery device according to the invention may preferably comprise a drive mechanism that acts on and which, in turn, acts on said drug container. In this regard, there may be a number of different designs that are available to specialists in this field, which can be used to perform the drive function to act on the container with the drug, with the result that the dose of the drug is delivered. This includes various types of energy storage products, such as those with mechanical or gas springs, and these are few of the possible ones.

Preferably, the drug delivery device may further comprise a trigger element. It can be moved from a first position in which it allows you to hold the specified drive mechanism, in a second position in which it allows you to release the drive mechanism. When the drive mechanism is released, the drug is given the opportunity to be forced through the specified element for delivery. The specified trigger element may have a number of designs. One of the preferred designs is a start button, which can be placed from the distal end of the device for the delivery of drugs and is adapted to be pressed into the body of the device when it is necessary to deliver a dose of the drug.

In accordance with one feasible solution of the present invention, it may further comprise a deadlock member movable between the locking position in which it prevents the trigger from moving from its first position to the second position and the unlocking position in which it allows the trigger to be moved from its first position to the second position. This solution ensures that the specified trigger cannot be displaced while the specified deadlock is activated. The actuation of the deadlock element can be accomplished through various actions. The preferred action may consist in the fact that this interlocking element has grooves in which the protrusions of the specified trigger element are placed, moreover, the interlocking element can be rotated so that the protrusions of the trigger element are located so that this trigger element can be moved to the second position. Other acceptable actions may include pressing the drug delivery device against the drug administration area, which brings the indicated interlock element out of the locking engagement with the specified trigger element.

In addition, the device may have an indicator to indicate that it has been used, which is provided, preferably, by a trigger element that is held in its second position.

According to a preferred solution of the present invention, it may be characterized in that said trigger element comprises at least one locking protrusion, and said drive mechanism comprises corresponding locking surfaces with respect to which said locking tabs are fixed when said trigger element is in its second position . In the case of this solution, it is guaranteed that the launch element is held securely in the second position, with the advantage that there is a clear and definite indication that the device has been used, because the user directly sees that the launch element is pressed. Also, the locking mechanism ensures that it is very difficult to manipulate the trigger element. On the contrary, it is securely locked in the second position inside the body of the device for drug delivery.

In accordance with one preferred solution of the present invention, said at least one locking protrusion comprises at least one flexible portion and an end surface facing in the distal direction of the device.

In addition, the specified at least one locking protrusion is integral with the proximal directed legs of the trigger element.

Moreover, said locking surfaces face in the proximal direction of the device, so that said surfaces are locked into engagement when said trigger element is in its second position.

According to one aspect of the present invention, said drive mechanism includes a holding member, a plunger member, a drive spring, and a signal generating member.

According to another aspect of the present invention, the annular edge is provided with cutouts that have lateral surfaces and through which said proximally directed legs of the trigger element can pass.

In accordance with a further aspect of the present invention, said at least one locking protrusion is biased by the side surfaces when the trigger is moved a predetermined distance from a first position to a second position, and such that when the end surface of said at least , one fixing protrusion passes these cutouts, said elastic section biases the specified at least one fixing protrusion, as a result of which the end surface is given of at least one locking protrusion is fixed using proximal directed surfaces of said annular edge.

In accordance with another aspect of the present invention, said trigger element comprises a substantially cylindrical distal portion forming a trigger button, which is provided by said interlock element, wherein said substantially cylindrical distal portion includes protrusions on its outer surface adapted to fit in the transverse and longitudinally extending grooves of the indicated deadlock element.

According to another aspect of the present invention, said deadlock member is in the locked position when said protrusions are located inside transversely extending grooves, and said deadlock member is in an unlocked position when said protrusions are located in longitudinally extending grooves.

 According to an additional aspect of the present invention, said holding element includes at least one distally directed leg, which may be flexible in the radial direction, and in which said at least one distally directed leg may have inwardly directed hooks made with the ability to fit inside cutouts or through holes of said piston rod, and outwardly projecting protrusions configured to interact with an inner surface of said ele cient start and with the through holes of said trigger member.

In accordance with another aspect of the present invention, the trigger element is in a first position when said trigger element is positioned around said distally directed legs so that said hooks are engaged inside said cutouts or through holes of said piston rod.

According to another aspect of the present invention, the trigger element is in a second position when said trigger button is fully placed inside said deadlock element so that said protrusions are able to enter inside the through holes, while said legs can move radially outward so that said hooks could disengage with the indicated piston rod.

In accordance with a further aspect of the invention, the drug delivery device is an injection device and, more specifically, a pen syringe or a syringe for self-injection.

These and other aspects of the present invention and its advantages will become apparent from the following detailed description of the present invention and from the accompanying drawings.

BRIEF DESCRIPTION OF THE DRAWINGS

In the following detailed description of the present invention, reference will be made to the accompanying drawings, in which:

In FIG. 1 is a perspective view of a drug delivery device according to the present invention;

FIG. 2 illustrates the device depicted in FIG. 1, disassembled;

FIG. 3 illustrates a detailed view of the device of FIG. one;

FIG. 4 illustrates a cross-sectional view of the device of FIG. one; and

In FIG. 5-7 are detailed views illustrating various functional states of the device of FIG. one;

In FIG. 8-9 are detailed views illustrating various functional states of an embodiment of the device of FIG. one.

DETAILED DESCRIPTION OF THE INVENTION

In FIG. 1 is a perspective view of a drug delivery device according to the present invention. The specified device contains a substantially cylindrical elongated body 10 having proximal and distal ends when viewed along the longitudinal axis L of the specified device. The proximal end of the device may additionally be equipped with a protective cap 20.

FIG. 2 illustrates the device depicted in FIG. 1, unassembled. Safety device 14 or tube-shaped structure, FIG. 2, is slidably positioned in the longitudinal direction inside said body and through the channel of the proximal end. The specified safety device 14 may have distally directed legs 15, in which each leg is provided with a tongue 16 at its distal end. The specified housing is adapted to accommodate a container 24 with a medicinal product with an attached element 28 for delivery or without it. The holder 22 of the container with the drug is located inside the housing and is configured to accommodate the specified container 24 with the drug. Said drug container holder may be partially located inside the safety device 14 so that said drug safety device can slide relative to both the drug container holder and the housing. The drug container 24 may include a removable stopper 26, FIG. 4, and drug delivery member 28. However, as indicated above, the drug delivery element 28 is not necessarily part of said drug container and may be a separate device element. As shown in FIG. 2, said drug delivery member may be a needle. The safety spring 18 may be located between the proximal end of the drug container holder 22 and an annular edge on the inner surface of the proximal end of said safety device 14 in order to push the device 14 in the proximal direction. It is also possible that said safety spring 18 may be between an annular edge on the inner surface of the housing and an annular edge on the inner surface from the proximal end of said safety device.

The side surface of the drug container holder 22 may be provided with a locking mechanism 30, FIG. 2 and 3. Said locking mechanism 30 includes at least one lever. The specified lever may be a balancer. The specified lever may be in the form of an outgoing longitudinal beam 32. The specified beam 32 can be attached in its middle to the holder 22 of the container with the drug using two articulated levers, forming a proximal end and a distal end. The specified beam may be an integral part of the holder 22 of the container with the medicinal product or be articulated with it. The distal end of the beam 32 may have a laterally extending edge 34, FIG. 3. The safety device 14 may be positioned relative to said beam 32 so that said tongues 16 are aligned along the sides of the beam 32, as will be explained further below.

In addition, the device may be equipped with an actuator 50, which includes a trigger lock member 36, a deadlock member 46 in the form of a guide clutch, and a trigger 48. Said trigger blocking element 36 may comprise a generally annular or cylindrical element 38 surrounding the drug container holder 22 and located distally relative to the beam 32, FIG. 3. The specified annular element 38 may have at least one proximal outgoing tongue 40 located on the same axis with the beam 32. The annular element 38 may further have distally directed legs 42. In the depicted embodiment, the annular element 38 includes two distally directed legs 42. As shown in FIG. 3, the distal portions of said legs 42 may extend into longitudinal cutouts or grooves 44 of the interlock member 46. Said trigger element 48 may be provided by said deadlock element 46. Trigger element 48 may comprise a generally tube-shaped distal portion provided with protrusions 52 on its outer surface, in which said protrusions 52 fit inside the grooves 44 of the interlocking member 46, as well as inside the transversely extending grooves 47 on the interlocking member 46, forming a locking joint. The specified tubular portion of the trigger element 48 may extend in the distal direction, forming a trigger button 54, which protrudes from the specified deadlock element in the distal direction. On the tube-like part of the trigger element 48, through holes 39 are located, the function of which will be explained below. The connection between the interlocking member 46 and the housing is such that it is prevented from unfastening the interlocking member from the housing, but rotation thereof relative to the housing is allowed. The connection between the deadlock member 46 and the trigger 48 is such that said trigger is able to move, more specifically, axially slide relative to said deadlock. The deadlock element also has the ability to rotate relative to the trigger element.

The trigger element 48 includes at least one locking protrusion 58, indicating generally in the distal direction, but with a certain deviation relative to the longitudinal axis L of the device. Said at least one locking protrusion 58, in the case of the illustrated embodiment, FIG. 6 is an integral part of the proximal directed legs 60 of the trigger 48. Each locking protrusion 58 includes at least one flexible portion 62 and an end surface 63, the latter facing in the distal direction of the device.

The device may additionally be equipped with a drive mechanism 90, including a holding element 70, a plunger element or an elongated piston rod 72, a drive spring 74, as well as a signal generation element 76, FIG. 2 and 4. Said piston rod 72 may be provided with a hollow space within which a drive spring 74 is arranged to spring the piston rod 72. The proximal end of said elongated piston rod 72 may be in contact with a stopper 26 of the drug container 24. The distal end of the drive spring 74 may be in contact with the transverse portion of said signal generating element 76, which is generally U-shaped. The signal generating element 76 may have proximally directed arms, and each arm may comprise an edge extending radially outward. The specified signal generation element 76 may be configured to partially surround said spring-loaded piston rod. The specified holding element 70 contains at least one, and more specifically, two distally directed legs 78, which can be flexible in the radial direction. The distal ends of said legs 78 may have inwardly extending hooks 80 and outwardly extending projections 79. Said hooks 80 may be adapted to fit inside cutouts or through holes 82 of piston rod 72 to hold it in place. FIG. 4, as will be explained later. These protrusions 79 may be configured to interact with an inner surface of said tubular portion of trigger element 48 and with through holes 39 located on said tubular portion of trigger element 48. The signal generating element 76 may axially extend through the retaining element 70. Said proximal directional legs 60 of the trigger element 48 may axially slide along grooves 66 on the outer surface of said retaining element.

Moreover, the trigger element 48 is configured to move from the first position in which it allows you to hold the specified drive mechanism, in the second position in which it allows you to release the drive mechanism 90, so that the drug is allowed to be expelled through the specified element 28 for delivery. The trigger element 48 is in a first position when said trigger element is positioned around said distally directed legs 78 so that said hooks 80 are engaged inside said cutouts or through holes 82 of said piston rod and protrusions 52 are aligned with transverse grooves 47. Element the launch is in the second position, when the specified start button 54 is completely placed inside the specified element interlock so that the protrusions 79 are able to enter the through holes 39 minutes of said trigger element, that is, these through-holes 39 are aligned with the projections 39, while the mentioned legs 78 are able to move radially outwardly so that said hooks 80 might come out of engagement with said piston rod.

In addition, the interlocking member 46 is configured to move between the locking position in which it prevents the triggering element 48 from moving from its first position to the second position and the unlocking position in which it allows the triggering element 48 to be moved from its first position to the second position. The device has an indicator to indicate that it has been used, which is provided by the trigger 48, which is held in its second position.

The interlocking member 46 is in the locked position when the protrusions 52 are located inside the transversely extending grooves 47. The interlocking member 46 is in the unlocked position when said protrusions 52 are located on the same axis as the longitudinally extending grooves 44.

In the assembled state of the drive mechanism, the drive spring 74 may be compressed between the proximal inner end surface of the piston rod 72 and the transverse part of the signal generation element 76. The edges of the signal generation element 76 extending radially outwardly can be engaged with the proximal annular surface of the holding element 70 in order to prevent the signal generation element 76 from moving in the distal direction by the drive spring 74. The piston rod 72 is thereby spring loaded in the proximal direction. As explained above, the trigger 48 may be positioned around said distally directed legs 78 so that said hooks 80 are in proper engagement with a cutout 82 on said spring-loaded piston rod. This means that the trigger 48 is in the first position when it allows the drive mechanism to be held. The protrusions 52 of the trigger element 48 are located inside the grooves 44 of the deadlock element 46, so that the deadlock element 46 is in the locked position, in which it prevents the trigger element 48 from moving from its first position to the second position. The legs 42 extend into the longitudinal grooves 44 of the interlock element 46 above the proximal directional legs 60 of the trigger element 48, so that the distal end surfaces of the legs 42 are aligned with the proximal edge of the transverse grooves 47 of the interlock element 46.

The distally directed surfaces 63 of the locking protrusions 58 are designed to interact with the locking surfaces 64 of the drive mechanism. More specifically, said fixing surfaces 64 may be proximal directed surfaces of the annular edge 68 on the outer surface of the retaining element 70. The specified annular edge 68 has cutouts with sides 65, and proximally directed legs 60 of the trigger 48 can extend through said cutouts. More specifically, said fixing surfaces 64 face in the proximal direction of the device.

The device is designed to operate as follows. When it is necessary to use the device, the protective cap 20 is removed. In order to deliver a dose of a drug, the device must be activated, which is done by rotating the deadlock element 46 relative to the launch element 48. This causes the transverse grooves 47 to slide relative to the protrusions 52 until these protrusions 52 are aligned with the longitudinal grooves 44 of the interlocking member 46 so that the protrusions 52 abut against the distal end surfaces of the legs 42. This means that the interlocking member 46 was moved from the locked position, in which it prevents the trigger 48 from moving from its first position to the second position, to the unlock position, in which it allows the trigger to move 48 from its first laying in the second position. However, pressing the start button 54 is prevented because the proximal directional tabs 40 abut against the edge 34. In order to allow pressing the start button, it is necessary to press the proximal end of the safety device 14 close to the drug administration zone. This causes the safety device 14 to axially slide in the distal direction of the device relative to the housing and the container holder, as a result of which the distally directed tabs 16 move in contact with the specified edge 34. Since the edge 34 is wedge-shaped, the tabs 16 will slide along the edge 34, exerting a radial force to the specified edge 34 and, thus, to the distal end of the beam 32, deflecting the distal end of the specified beam, together with the specified edge, radially inward.

After the edge 34 has been shifted radially inward, the proximal directional tabs 40 of the trigger lock member 36 no longer abut against said edge 34, making it possible to move the trigger lock member 36 in the proximal direction. Thus, when the start button 54 is pressed in the proximal direction, the protrusions 52 are guided into the longitudinal grooves 44. Since the protrusions 52 abut against the distal end surfaces of the legs 42, the annular element 38 moves in the proximal direction, FIG. 4. Further, the displacement of the start button 54 towards the proximal end of the device, so that the specified start button is completely placed inside the interlock element 46, allows the protrusions 79 to enter the through holes 39 so that the legs 78 move radially outward, allowing the hooks 80 to exit gearing with the piston rod 72. This means that the trigger element is in the second position. The fact that the start button is completely placed inside the deadlock element 46 means that even a part of the start button does not protrude distally from the deadlock element, that is, the transverse distal outer surface of the start button is flush with the distal annular edge of the deadlock element 46. The piston rod 72, after uncoupling the hooks 80, can be pushed proximally with a drive spring 74 and can act on the stopper 26 inside the drug container 24 so as to deliver a dose of the drug through the drug delivery member 28 in the drug administration area the drug. This means that the trigger 48 was moved from the first position in which it allows the drive mechanism 90 to be held to the second position in which it allows the drive mechanism 90 to be released so that the drug is expelled through the delivery member 28. The proximal movement of the annular element 38 causes the proximal directional tabs 40 to move in the proximal direction, as a result of which it can be shifted radially outward relative to the edge 34, so that the specified edge is held so that it is pressed inward in the radial direction.

According to the present invention, when the release button 54 is displaced in the proximal direction, also the legs 60 with the locking protrusions 58 are displaced in the proximal direction. Said locking protrusions will slide along and also deflect by means of the side surfaces 65, FIG. 6 and 7, cutouts in an annular edge 68 on the outer surface of the retaining element 70. When the start button 54 was pressed a certain distance in the proximal direction, the distal end surfaces 63 of the locking protrusions 58 passed these cuts, the flexible sections 62 will push the locking protrusions 58 back into the original position. Now, as can be seen in FIG. 7, the distally directed end surfaces 63 of the locking protrusions 58 abut against the proximal directed surfaces 64 of the annular edge 68. This means that the locking protrusions 58 of the trigger element and the corresponding locking surfaces 64 of the drive mechanism are locked when the trigger element 48 is in its second position.

In this position, the dose of the drug was delivered, as indicated by the trigger element 48 and, thus, the trigger button 54, held pressed, the second position. Therefore, it is obvious that the device has been used and should be decommissioned. In this regard, the side surface of the start button 54 may be provided with a color indication indicating an unused or ready-to-use device, while in the used position the indicated color indication is no longer visible, since the start button 54 is located inside the housing 10. This means that the device, or more specifically the trigger element, has an indicator to indicate that the device has been used.

When the indicated dose has been delivered, the device may be withdrawn from the drug administration zone. This, in turn, causes the safety device 14 to move proximal to the housing and the container holder using the safety spring 18. The proximal movement of the safety device 14 will cause the proximal end of the beam 32 to free, causing the beam to bend outward in the radial direction, due to the voltage accumulated in said beam 32 using proximally directed reeds 40 as they move over the edge 34. The beam 32 can thus reach a horse the final position in which the proximal end of the beam 32 restricts the movement of the safety device 14 in the distal direction. The proximal end of the longitudinal beam 32 can be located between the distally directed tongues 16 of the safety device 14, blocking the safety device 14 against movement in the distal direction and allowing safe disposal of the device.

In FIG. 8-9 depict an embodiment of a locking surface 64 and a locking protrusion 58 of the present invention, in which the distal contact surface 100 of the annular edge 68, in accordance with FIG. 6 is provided with a tapered or inclined portion 104. Additionally, the locking protrusion 58 has a notch or groove 102. Thus, during activation of the start button 54, said groove 102 in said locking protrusion 58 is forced to engage with said tapered section 104 of said annular edge 68, so that the contact between the groove 102 and the end surface of the beveled portion 104 will elastically push back the locking protrusion 58 and then cause it to bounce sharply back against the beveled portion 104 to provide both sound and tactile information about the progress of drug dose delivery. Also, as in the case of the previous embodiment, the movement of the device triggering element 48 from its second position is prevented. In addition, in the embodiment depicted in FIG. 8 and 9, the locking protrusion 58 has an increased thickness t to further block the device trigger 48 in its second position.

While the invention has been illustrated and described in detail using the drawings and the foregoing description, such illustration and description should be considered as illustrative or exemplary and non-limiting. It should be appreciated that changes and modifications may be made by those skilled in the art to the extent of the following claims. In particular, the present invention encompasses further embodiments with any combination of features from the various embodiments described above or below.

In addition, in the claims, the word “comprising” does not exclude other elements or steps, and the use of the singular of the components does not exclude the presence of these components in the plural. One component can perform the functions of several elements listed in the claims. The terms “substantially”, “about”, “approximately” and the like with reference to a property or value, in particular, also define a particular property or a specific value, respectively. Any reference positions in the claims should not be construed as limiting the scope.

It should be appreciated that the embodiment described above and shown in the drawings is to be considered only a non-limiting example of the present invention and that it can be modified in many ways within the scope of the claims.

Claims (17)

1. A device for drug delivery, containing:
- a housing (10), configured to accommodate a container (24) with a drug with an attached element (28) for delivery or without it;
- a drive mechanism (90) made with the possibility of acting on it with a container (24) with a medicinal product and at the same time made with the possibility of influencing a container (24) with a medicinal product;
- the trigger element (48), configured to move from the first position in which it allows the drive mechanism (90) to be held, to the second position in which it allows the drive mechanism (90) to be released, while it is possible to displace the drug through the element (28) for delivery;
- an interlocking element (46) configured to move between the locking position in which it prevents the triggering element (48) from moving from its first position to the second position and the unlocking position in which the triggering element (48) is moved from its first position in the second position, and the device has an indicator to indicate that it was used, provided by the trigger element (48), which is held in its second position, characterized in that the said element t start includes at least one locking protrusion (58), and said drive mechanism comprises corresponding locking surface (64) against which the locking projections (58) are fixed, when the element (48) is run in its second position. 2. The device according to claim 1, wherein said at least one locking protrusion (58) includes at least one flexible portion (62) and an end surface (63) facing in the distal direction of the device. 3. The device according to claim 2, wherein said at least one locking protrusion (58) is integral with the proximally directed legs (60) of the trigger element (48). 4. The device according to claim 3, wherein said fixing surfaces (64) are turned in the proximal direction of the device, while said surfaces (63, 64) are made with the possibility of locking engagement when said trigger element (48) is in its second position. 5. The device according to claim 4, in which the drive mechanism (90) includes a holding element (70), a plunger element (72), a drive spring (74) and a signal generation element (76). 6. The device according to claim 5, in which the fixing surfaces (64) are proximal directed surfaces of the annular edge (68) on the outer surface of the retaining element (70). 7. The device according to claim 6, in which the annular edge (68) is provided with cutouts that have side surfaces (65), while the proximally directed legs (60) of the trigger element (48) are configured to pass through the cutouts. 8. The device according to claim 7, wherein said at least one locking protrusion (58) is biased by the side surfaces (65) when the trigger element (48) is moved a predetermined distance from the first position to the second position, while passing cutouts by the end surface (63) of at least one fixing protrusion (58), the flexible portion (62) is arranged to bias the specified at least one fixing protrusion (58), and the end surface (63) of at least one fixing protrusion and (58) is fixed with the help of proximally directed surfaces (64) of said annular edge (68). 9. The device according to claim 8, in which said at least one locking protrusion (58) is provided with a groove (102) provided for providing a tactile and sound response when passing said side surface (65). 10. The device according to claim 9, wherein said side surface (65) is provided with a beveled portion (104). 11. The device according to claim 1, wherein said trigger element (48) comprises a substantially cylindrical distal portion forming a trigger button (54) passing through the interlock element (46), said substantially cylindrical distal portion including protrusions ( 52) on its outer surface, configured to fit transversely (47) and longitudinally (44) passing grooves of the interlock element (46). 12. The device according to claim 11, in which the interlock element (46) is in the locked position when the protrusions (52) are located inside the transversely extending grooves (47), while the interlock element (46) is in the unlocked position when the protrusions (52) ) are located in longitudinally extending grooves (44). 13. The device according to any one of paragraphs. 5-8, in which the holding element (70) includes at least one distally directed leg (78), which may be flexible in the radial direction, while the specified at least one distally directed leg (78) may have directed inward hooks (80) configured to fit inside cutouts or through holes (82) of the piston rod (72) and outwardly projecting protrusions (79) configured to interact with the inner surface of the trigger element (48) and with through holes (39) element (48) run ka. 14. The device according to claim 13, in which the trigger element (48) is in the first position when said trigger element is located around said distally directed legs (78), said hooks (80) being engaged with said cutouts or through holes (82) piston rod (72). 15. The device according to p. 13, in which the trigger element (48) is in the second position when said trigger button (54) is completely placed inside the deadlock element (46), while the protrusions (79) are configured to enter the through holes ( 39), and the legs (78) are made with the ability to move radially outward to ensure the exit of the hooks (80) from engagement with the piston rod (72). 16. The device according to claim 1, which is an injection device. 17. The device according to p. 7, which is a syringe pen or syringe for self-injection.

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