RU2321410C1 - Method for treating inflammatory process cases - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: method involves intravenously introducing 1-5 ml of 10% calcium gluconate solution. Then, 0.5% Novocain solution is subcutaneously introduced into the region of lymph nodes regionally localization with respect to inflammatory focus. Next to it, 0.2-1.0 ml of solution containing furosemide, No-spa, Analgin and Dexamethazone together with 0.5-1.0 ml of Novocain solution in turn and sequentially with 5 min long pause combined with solution containing 0.2-0.5 ml of Cephazoline or Ampiox or Claforan. The procedures are prescribed once a day during 3-5 days.

EFFECT: enhanced effectiveness of treatment.

Description

The invention relates to medicine and can be used in the treatment of various inflammatory diseases in various localization of inflammatory processes, in particular in inflammatory processes of the genitourinary system (endometritis, prostatitis, orchitis, cystitis, pyelonephritis); with inflammation of the brachial nerve (plexitis); with inflammation of the lymph nodes (lymphadenitis)

Inflammatory diseases of various organs are a common pathology that determines the development of a number of complications, disability and disability of the population. Therefore, the development of methods for treating this pathology at all times has been an urgent issue.

In the treatment of acute and chronic inflammatory processes, traditional methods of administering drugs to the body are commonly used. However, they often turn out to be ineffective.

Recently, endolymphatic and lymphotropic routes of drug administration have become widespread. The fact of increasing the effectiveness of antibiotics, immunomodulators, protease inhibitors, cytostatics, etc. when directed into the lymphatic system is undeniable (Levin Yu.M. Fundamentals of therapeutic lymphology. M., Medicine, 1986, 288 pp. And Buyanov V.M. and other Medicinal saturation of the lymphatic system, Kiev, 1991, 134 pp.).

The closest analogue can be considered a method of treating an inflammatory process, for example, a method of treating nonspecific metroendometritis and acute inflammatory diseases of the uterine appendages, namely, when laparoscopy, a microirrigator is installed between the leaves of the wide uterine ligament and fixed with one or two vicryl sutures. An antibiotic is injected lymphotropically through the microigrigator once a day for 3-5 days (Goldyreva E.V. Clinical and morphological substantiation of the method of lymphotropic therapy of acute nonspecific metroendometritis, Abstract of Ph.D., MD, Novosibirsk, 2000, 23 pp.).

However, this method is not without drawbacks, because it requires intervention in a specialized clinic with the implementation of surgical intervention, which during infection can be accompanied by the spread of microorganisms to surrounding tissues, followed by suppuration and generalization of the process. In addition, this method requires appropriate tools and is expensive.

The purpose of the invention is the achievement of the treatment effect with the simplicity of the method due to the combination of the pharmacological activity of the selected drugs, providing a multicomponent effect on all pathogenesis links during inflammation.

The method is as follows. Before the start of each lymphotherapy procedure, 1-5 ml of 10% calcium gluconate solution is intravenously administered. Then, in the region of the regional inflammatory site of the lymph nodes, subcutaneously, without removing the needle, 1-10 ml of a 0.5% solution of novocaine is administered and then the following drugs are administered alternately and sequentially in the form of official solutions: 0.2-1.0 ml of furosemide, 0.2-1.0 ml of no-shpa, 0.2-1.0 ml of dipyrone, 0.2-0.5 ml of dexamethasone and a solution containing 0.2-0.5 mg of cefazolin or ampiox , or claforan, with the introduction of furosemide, no-shpa, analgin and dexamethasone is carried out together with 0.5-1.0 ml of a 0.5% solution of novocaine. To prepare the antibiotic solution, 1000 mg of the antibiotic is diluted with 10 ml of novocaine solution. The procedure is performed once a day for 3 to 5 days, depending on the duration of the inflammatory process (if the process is chronic, then 5 procedures).

Examples of the method of treatment for specific patients.

Example 1

Patient S. 1944, complained of constant pain in the left shoulder, at the tips of the fingers, which has been disturbing for 6 months. The efficiency of the left hand is 30%. Before contacting us, she received inpatient treatment several times with a neuropathologist with a diagnosis of plexitis of the left brachial nerve.

Before each lymphotherapy procedure, 5.0 ml of a 10% calcium gluconate solution was intravenously administered.

5 procedures were performed, once a day, for 5 days.

In one procedure, the following was done:

Into the region of accumulation of lymph nodes of the left axillary region was introduced subcutaneously

- Novocaine solution 0.5% 4.0 ml;

and with an interval of 5 minutes, the following drugs were introduced in the form of official solutions:

- furosemide 0.5 ml with 1.0 ml novocaine;

- no-spa 1.0 ml with 1.0 ml novocaine;

- Analgin 1.0 ml with 1.0 ml novocaine;

- dexamethasone 0.5 ml with 1.0 ml novocaine;

- and a solution containing cefazolin, 0.5 mg.

After the first procedure, the pain symptoms subsided, after the third, she could work with her left hand for 70%.

After 5 procedures, some tingling at the fingertips remained, but within a few days these manifestations of the disease disappeared.

Example 2

Patient A., 1957, complained of pain in her right shoulder, inability to raise her hands up, and poor working capacity of her right hand. Sick for several years and several times received both inpatient and outpatient treatment with a diagnosis of plexitis of the right brachial nerve.

Before each procedure, 5.0 ml of 10% calcium gluconate solution was intravenously administered.

5 procedures were performed, once a day, for 5 days.

Into the region of accumulation of lymph nodes of the right axillary region was introduced subcutaneously

- Novocaine solution 0.5% 4.0 ml;

with an interval of 5 minutes, the following drugs are introduced in the form of official solutions:

- furosemide 0.5 ml with 1.0 ml novocaine;

- no-spa 1.0 ml with 1.0 ml novocaine;

- Analgin 1.0 ml with 1.0 ml novocaine;

- dexamethasone 0.5 ml with 1.0 ml novocaine;

- a solution containing cefazolin, 0.5 mg.

The pain disappeared, increased efficiency. After the third procedure, she could calmly raise her right hand.

Example 3

Patient Sh. 11 years old, complained of frequent urination. The urologist was diagnosed with cystitis.

A course of penicillin and furadonin is prescribed. Frequent urination decreased slightly, but 3 days after treatment, the frequency of urination increased again.

Conducted 2 procedures of lymphotherapy.

Before the procedure, 2.5 ml of 10% calcium gluconate solution was intravenously administered.

2 procedures were performed within 2 days. In the region of the accumulation of the lymph nodes of the inguinal region is introduced subcutaneously

- 0.5% solution of novocaine 2.0 ml;

with an interval of 5 minutes, the following drugs were introduced in the form of official solutions:

- furosemide 0.3 ml with 1.0 ml novocaine;

- no-spa 0.3 ml with 1.0 ml novocaine;

- analgin 0.4 ml with 1.0 ml novocaine;

- dexamethasone 0.2 ml with 1.0 ml novocaine;

- solution containing ampiox, 0.3 mg.

All signs of the disease on the second day disappeared completely.

Example 4

Patient N. 2 years old. According to the mother, the child has frequent urination, and the urologist has been diagnosed with cystitis.

Before the lymphotherapy procedure, 1.5 ml of 10% calcium gluconate solution was intravenously administered.

2 procedures were performed within 2 days.

In the region of the accumulation of the lymph nodes of the inguinal region is introduced subcutaneously

- 0.5% solution of novocaine 1.5 ml;

with an interval of 5 minutes, the following drugs were introduced in the form of official solutions:

- furosemide 0.2 ml with novocaine 0.5 ml;

- no-spa 0.2 ml with novocaine 0.5 ml;

- analgin 0.2 ml with 0.5 novocaine;

- dexamethasone 0.2 ml with 0.5 ml novocaine;

- solution containing ampiox, 0.2 mg.

All signs of the disease disappeared on the 2nd day.

Example 5

Patient U. 1968, complained of frequent urination and discharge with wet clothes when waking up, despite repeated treatment by a urologist. According to the patient, he was treated several times for chronic prostatitis.

Before the procedures, 5.0 ml of a 10% calcium gluconate solution was intravenously administered.

3 procedures were performed within 3 days.

In the region of the accumulation of the lymph nodes of the inguinal region is introduced subcutaneously

- 0.5% solution of novocaine 3.0 ml;

with an interval of 5 minutes, the following drugs were introduced in the form of official solutions:

- furosemide 0.5 ml with 1.0 ml novocaine;

- no-spa 0.8 ml with 1.0 ml novocaine;

- Analgin 1.0 ml with 1.0 ml novocaine;

- dexamethasone 0.5 ml with 1.0 ml novocaine;

- a solution containing cefazolin, 0.5 mg.

After the procedures, all symptoms of the disease disappeared.

Example 6

Patient Sh. 1971, complained of pain, swelling, and severity of the scrotum. Was diagnosed with orchitis.

Before the procedures, 5.0 ml of 10% calcium gluconate solution was intravenously administered.

3 procedures were performed within 3 days. In the region of accumulation of the lymph nodes of the inguinal region was injected subcutaneously

- 0.5% solution of novocaine 3.0 ml;

with an interval of 5 minutes, the following drugs were introduced in the form of official solutions:

- furosemide 0.4 ml with 1.0 ml novocaine;

- no-spa 0.5 ml with 1.0 ml novocaine;

- analgin 0.5 ml with 1.0 ml novocaine;

- dexamethasone 0.2 ml with 1.0 ml novocaine;

- a solution containing cefazolin, 0.5 mg.

All signs of inflammation of the scrotum have disappeared.

Example 7

Patient Z. 1958, complained of pain in the lower abdomen, discharge from the external genital tract, an increase in the size of the uterus, low-grade fever, and malaise.

The gynecologist was diagnosed with endometritis.

Before the procedure, 400 ml of hemodesis were transfused intravenously and 5.0 ml of a 10% solution of calcium gluconate was introduced.

The dropper is carried out before the 1st and 3rd procedures.

5 procedures were performed within 5 days.

In the region of accumulation of the lymph nodes of the inguinal region subcutaneously was administered

- 0.5% solution of novocaine 4.0 ml;

with an interval of 5 minutes, the following drugs were introduced in the form of official solutions:

- furosemide 0.5 ml with 1.0 ml novocaine;

- no-spa 0.7 ml with 1.0 ml novocaine;

- Analgin 1.0 ml with 1.0 ml novocaine;

- dexamethasone 0.5 ml with 1.0 ml novocaine;

- a solution containing claforan, 0.5 mg.

After the 3rd procedure, the discharge disappeared, the pain subsided, the uterus began to decrease in size, the temperature dropped. After the 5th procedure, the healing process began.

Example 8

Patient N. 1982, complained of discharge from the external genital tract, pain in the lower abdomen, a slight increase in the size of the uterus. A smear test was taken. The gynecologist was diagnosed with endometritis of gonorrheal etiology.

A single intravenous dropper was carried out with a 0.9% NaCl solution in a volume of 400 ml.

Before the procedure, intravenously 5.0 ml of 10% calcium gluconate solution.

3 procedures were performed within 3 days.

In the region of accumulation of the lymph nodes of the inguinal region subcutaneously was administered

- 0.5% solution of novocaine 3.0 ml;

with an interval of 5 minutes, the following drugs were introduced in the form of official solutions:

- furosemide 0.5 ml with 1.0 ml novocaine;

- no-spa 0.5 ml with 1.0 ml novocaine;

- analgin 0.5 ml with 1.0 ml novocaine;

- dexamethasone 0.4 ml with 1.0 ml novocaine;

- a solution containing cefazolin, 0.5 mg.

After treatment, all symptoms of the disease disappeared.

Example 9

Patient X. 1.5 years old. According to the mother, the child a week ago the lymph node behind the ears increased. The doctor of the clinic prescribed an antibiotic for oral administration and a compress. But there were no changes, and the patient turned to us. Diagnosed with lymphadenitis of the posterior lymph nodes.

1.5 ml of a 10% calcium gluconate solution was intravenously administered.

2 procedures were performed within 2 days.

In the region of the lymph nodes accumulation behind m. Sternocleidomastoideus subcutaneously administered

- 0.5% solution of novocaine 1.5 ml;

with an interval of 5 minutes, the following drugs were introduced in the form of official solutions:

- furosemide 0.3 ml with 0.5 ml novocaine;

- no-spa 0.2 ml with 0.5 ml novocaine;

- analgin 0.2 ml with 0.5 ml novocaine;

- dexamethasone 0.2 ml with 0.5 ml novocaine;

- Ampiox solution 0.2 mg.

After two treatments, all signs of lymphadenitis disappeared.

Example 10

Patient A. 1965. She complained of pain in the area of both kidneys, turbidity of the urine, malaise, puffiness of the face.

When analyzing urine, protein is determined above the norm, white blood cells, cylinders, red blood cells. Was diagnosed with pyelonephritis.

A month ago, she was treated in the urology department.

5.0 ml of 10% calcium gluconate solution was intravenously administered.

5 procedures were performed within 5 days.

In the region of the accumulation of the lymph nodes of the inguinal region is introduced subcutaneously

- 0.5% solution of novocaine 3.0 ml;

with an interval of 5 minutes, the following drugs were introduced in the form of official solutions:

- furosemide 0.5 ml with 1.0 ml novocaine;

- burden 1.0 ml with 1.0 ml novocaine;

- Analgin 1.0 ml with 1.0 ml novocaine;

- dexamethasone 0.5 ml with 1.0 ml novocaine;

- a solution containing cefazolin, 0.5 mg.

After 5 procedures, the patient noted an improvement in general condition, puffiness, malaise disappeared, the pain subsided. In the analysis of urine, the protein is normal, single leukocytes and cylinders are noted.

Thus, the proposed method allows you to effectively treat inflammatory diseases of various nature and localization of the pathological process due to the multicomponent effect on the pathogenesis of the disease. The method is simple to execute, does not require expensive techniques, the course of treatment is short. The method can be widely used in both inpatient and outpatient settings.

Claims (1)

A method of treating inflammatory processes, including the procedures of lymphotropic drug administration, characterized in that 1-5 ml of a 10% solution of calcium gluconate is intravenously administered before each procedure, then 1-10 ml 0 are injected subcutaneously in the area of the regional inflammatory focus of the lymph nodes , A 5% solution of novocaine and then, with an interval of 5 minutes, 0.2-1.0 ml of furosemide solution, 0.2-1.0 ml of no-shpa solution, 0.2-1.0 ml of solution are introduced alternately and sequentially analginum, 0.2-0.5 ml of dexamethasone solution and solution, s holding 0.2-0.5 mg of cefazolin or ampiox, or claforan, while the introduction of furosemide, no-shpa, analgin and dexamethasone is carried out together with 0.5-1.0 ml of a 0.5% solution of novocaine, the procedures are carried out for 3-5 days once a day.