RU2189834C1 - Disinfecting agent "veltodez" - Google Patents

Abstract

FIELD: medicine. SUBSTANCE: invention relates to an agent used as a disinfecting agent for disinfection of surface and articles of medicinal designation. Agent comprises carbamide didecyldimethylammonium bromide clathrate, organic monatomic alcohol, sodium hydrocarbonate and water. The definite ratio of components enhances a bactericidal activity, antiseptic properties and effectiveness of the composition. Agent effects on microorganisms, spores and green algae. EFFECT: enhanced effectiveness of agent. 4 cl, 3 ex

Description

 The invention relates to disinfectants used in the national economy, medicine, veterinary medicine, food industry enterprises, in everyday life.

 It can be used for disinfection in various fields: medical institutions of various profiles, Ministry of Emergency Situations, ambulance stations, disinfection stations, children's school and preschool institutions, sports and health centers, sanatoriums, dispensaries, resorts; objects of public utilities, on various types of transport, veterinary medicine, agriculture, catering and food processing enterprises and other areas of the national economy.

 Closest to the proposed invention is a disinfectant containing urea didecyldimethylammonium bromide clathrate, organic alcohol, sodium nitrate and water (RU, 2158142, A 61 L 2/18, 1999).

 This tool has a wide spectrum of antimicrobial activity when used in various fields. However, it has increased toxicity.

 The technical result of the invention is a simultaneous increase in the bactericidal, sporocidal activity of the composition, increased economic efficiency, reduced costs and reduced toxicity, increased use of working solutions, as well as the creation of a disinfectant with an optimally balanced composition and with a reduced concentration of working solutions.

This result is achieved by creating a disinfectant containing carbamide didecyldimethyl ammonium bromide clathrate, an organic monohydric alcohol, a salt of weak mineral acids and water, using sodium bicarbonate as a salt of weak mineral acids and using a mixture of sodium carbamide didecyldimethyl ammonium bromide preheated to 40 ^{° C.} bicarbonate and water, with a ratio of components, wt.%: urea didecyldimethylammonium bromide clathrate 15.0-30.0; organic monohydric alcohol 5.0-20.0: sodium bicarbonate 0.1-0.5; water the rest.

 In addition, it is possible to add a fragrance of 0.01-0.2 wt.% And an organic dye of 0.01-0.1 wt.%. Ethanol can be used as alcohol. As water can use drinking or deionized water.

 The technical result is achieved due to the synergism of the components taking into account temperature factors.

 The tool "Veltodez" has antimicrobial activity against bacteria (including causative agents of tuberculosis and anthrax), dermatophytes, yeast-like fungi of the genus Candida, and also inactivates viruses (hepatitis B, C, influenza, parainfluenza, herpes, HIV infection).

 The didecyldimethylammonium bromide contained in the urea clathrate is a surfactant, refers to cationic quaternary ammonium compounds and is a white, finely divided, crystalline powder, odorless and tasteless, has disinfecting and washing properties, is one of the active ingredients of the composition.

 Ethyl alcohol or any other organic alcohol, both from food raw materials and technical, is used to increase the solubility of the urea didecyldimethylammonium bromide clathrate and increase the antimicrobial activity of the composition.

 Sodium bicarbonate is introduced into the composition in order to soften and demineralize water, which increases the bactericidal properties of the composition and increases its stability.

 Fragrance is used to flavor the composition. Dyes can be organic or food, are introduced with the aim of a more rapid visual difference in composition from other agents used at various objects.

 Drinking water is more affordable and cheaper, which reduces the cost of the composition for consumers.

The disinfectant composition "Veltodez" is prepared as follows:
Example 1

79.9 g of deionized water are placed in the reactor, 0.1 g of sodium bicarbonate and 15 g of didecyldimethylammonium bromide carbamide clathrate are added. The mixture is heated to 40 ^{° C.} and stirred for 10-15 minutes. Then pour 5 g of ethyl alcohol or other alcohol, mix for 20-30 minutes, allow to stand for 1.5 hours. The resulting solution was filtered.

 Example 2

49.5 g of drinking water are placed in the reactor, 0.5 sodium bicarbonate and 30 g of didecyldimethylammonium bromide urea clathrate are added. The mixture is heated to 40 ^{° C.} and stirred for 10-15 minutes. Then pour 20 g of ethyl alcohol or other alcohol, mix for 20-30 minutes, allow to stand for 1.5 hours. The resulting solution was filtered.

 Example 3

52.9 g of drinking water are placed in the reactor, 0.5 g of sodium bicarbonate and 4.5 g of didecyldimethyl ammonium bromide urea clathrate are added. The mixture is heated to 40 ^{° C.} and stirred for 10-15 minutes. Then pour 20 g of ethyl or other alcohol, mix for 20-30 minutes. Alternately add 2 g of perfume and 0.1 g of dye, mix and allow to stand for 1.5 hours. The resulting solution was filtered.

The composition "Veltodes" is a colorless or light yellow viscous transparent or slightly opalescent liquid, with a slight alcohol smell or odor of perfume. It mixes with water in any proportions and is stable during storage for 5 years at a temperature of + 4 to + 30 ^o C. Working solutions "Veltodez" remain active after repeated use for 20 days, and unused working solutions do not lose their activity within 10-15 days. The composition cannot be mixed with soaps and anionic surfactants.

 The working solution is prepared by diluting the composition with an appropriate volume of drinking water. Use 0.5%, 1%, 2.5%, 4.0%, 5% solutions.

 Veltodez solutions have antimicrobial activity against bacteria, including tuberculosis, anthrax, dermatophytes, yeast-like fungi of the Candida genus, and also inactivate viruses (hepatitis B, C, HIV infection, herpes, influenza, parainfluenza).

 Veltodez solutions have detergent, deodorizing, anticorrosive properties, and have a residual effect.

The composition "Veltodez" is intended for use during:
current and final disinfection of indoor surfaces, patient care items, linen, dishes, sanitary equipment, cleaning material, medical devices (including surgical and dental instruments, flexible and rigid endoscopes, medical instruments for flexible endoscopes);
preventive disinfection of premises and equipment, linen, dishes at communal facilities, catering establishments;
general cleaning in medical and child care facilities;
disinfection and pre-sterilization cleaning of medical devices (including surgical and dental instruments, flexible and rigid endoscopes, medical instruments for flexible endoscopes), combined in one process;
pre-sterilization cleaning of dental instruments in a mechanized way using ultrasound;
for disinfection of linen and dishes with anthrax;
for disinfection of equipment, inventory, containers and surfaces of industrial premises in the dairy and meat industry.

 The tool "Veltodez" refers to low toxicity compounds; has a weak local irritant effect on the skin and moderate on the mucous membranes of the eyes. It does not have sensitizing and cumulative properties. The composition "Veltodes" does not have distant manifestations (mutagenic, embryotoxic, teratogenic, gonadotropic).

 In addition, the composition does not form environmentally hazardous compounds.

 Less concentrated working solutions are used. So, for example, when disinfecting objects with Veltodez solutions for tuberculosis, the concentration of working solutions is used, which is 2 times lower than the concentration of solutions used in the closest analogue.

Benefits:
- The combined process of disinfection and pre-sterilization cleaning;
- the repeated use of the composition for 20 days for disinfection and pre-sterilization cleaning of medical instruments, including endoscopes, due to the high antimicrobial activity and stability of the composition;
- a wide range of antimicrobial activity of the composition, a wide scope of application by one means;
- the simultaneous combination of several properties in one (bactericidal, virucidal, sporocidal, fungicidal, washing, deodorizing, anticorrosive, pre-sterilization cleaning agents);
- anticorrosive properties of the composition will save and increase the life of materials (tools, underwear, equipment, etc.);
- the safety of the composition for the health of people, including children,
- environmental safety of the composition;
- the stability of the composition for 5 years.

 - decrease in the concentration of the working solutions used.

Claims (3)

1. A disinfectant, including urea didecyldimethyl ammonium bromide clathrate, an organic monohydric alcohol, a salt of weak mineral acids and water, characterized in that sodium bicarbonate is used as a salt of weak mineral acids and a mixture of sodium didecyldimethyl ammonium bromide clathrate pre-heated to 40 ^° C is used. and water, in the following ratio of components wt. %:
Urea didecyldimethylammonium bromide clathrate - 15.0-30.0
Organic monohydroxy alcohol - 5.0-20.0
Sodium bicarbonate - 0.1-0.5
Water - Else
2. The disinfectant according to claim 1, characterized in that ethanol is used as the organic monohydroxy alcohol.  3. The disinfectant according to any one of paragraphs. 1 and 2, characterized in that the quality of the water used drinking water or deionized.  4. The disinfectant according to any one of paragraphs. 1-3, characterized in that the additional use of 0.01-2.0 wt. % perfumes and organic dye 0.01-0.1 wt. %