RU2017123618A - Поколинамиды с фунгицидной активностью - Google Patents
Поколинамиды с фунгицидной активностью Download PDFInfo
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- 230000000855 fungicidal effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 claims 26
- 241000196324 Embryophyta Species 0.000 claims 24
- 229910052739 hydrogen Inorganic materials 0.000 claims 11
- 239000001257 hydrogen Substances 0.000 claims 11
- 125000000217 alkyl group Chemical group 0.000 claims 8
- 244000053095 fungal pathogen Species 0.000 claims 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 241000540505 Puccinia dispersa f. sp. tritici Species 0.000 claims 6
- 125000003545 alkoxy group Chemical group 0.000 claims 6
- 125000003118 aryl group Chemical group 0.000 claims 6
- 241000221785 Erysiphales Species 0.000 claims 4
- 241000233866 Fungi Species 0.000 claims 4
- 241000209140 Triticum Species 0.000 claims 4
- 235000021307 Triticum Nutrition 0.000 claims 4
- 150000002431 hydrogen Chemical class 0.000 claims 4
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- 239000002689 soil Substances 0.000 claims 4
- 244000068988 Glycine max Species 0.000 claims 3
- 235000010469 Glycine max Nutrition 0.000 claims 3
- 240000005979 Hordeum vulgare Species 0.000 claims 3
- 235000007340 Hordeum vulgare Nutrition 0.000 claims 3
- 241000682645 Phakopsora pachyrhizi Species 0.000 claims 3
- 241001360088 Zymoseptoria tritici Species 0.000 claims 3
- 125000003342 alkenyl group Chemical group 0.000 claims 3
- 235000000832 Ayote Nutrition 0.000 claims 2
- 240000004244 Cucurbita moschata Species 0.000 claims 2
- 235000009854 Cucurbita moschata Nutrition 0.000 claims 2
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 claims 2
- 241000736122 Parastagonospora nodorum Species 0.000 claims 2
- 241000228452 Venturia inaequalis Species 0.000 claims 2
- 230000000844 anti-bacterial effect Effects 0.000 claims 2
- 239000003899 bactericide agent Substances 0.000 claims 2
- 239000000417 fungicide Substances 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 239000002917 insecticide Substances 0.000 claims 2
- 239000005645 nematicide Substances 0.000 claims 2
- 239000000575 pesticide Substances 0.000 claims 2
- 235000015136 pumpkin Nutrition 0.000 claims 2
- 241000213004 Alternaria solani Species 0.000 claims 1
- 235000016068 Berberis vulgaris Nutrition 0.000 claims 1
- 241000335053 Beta vulgaris Species 0.000 claims 1
- 241000895523 Blumeria graminis f. sp. hordei Species 0.000 claims 1
- 241000895502 Blumeria graminis f. sp. tritici Species 0.000 claims 1
- 241000530549 Cercospora beticola Species 0.000 claims 1
- 241000222235 Colletotrichum orbiculare Species 0.000 claims 1
- 241000510928 Erysiphe necator Species 0.000 claims 1
- 241000896246 Golovinomyces cichoracearum Species 0.000 claims 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims 1
- 241001330975 Magnaporthe oryzae Species 0.000 claims 1
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 241001123583 Puccinia striiformis Species 0.000 claims 1
- 241000520648 Pyrenophora teres Species 0.000 claims 1
- 241001515790 Rhynchosporium secalis Species 0.000 claims 1
- 240000003768 Solanum lycopersicum Species 0.000 claims 1
- 244000301083 Ustilago maydis Species 0.000 claims 1
- 235000015919 Ustilago maydis Nutrition 0.000 claims 1
- 240000006365 Vitis vinifera Species 0.000 claims 1
- 235000014787 Vitis vinifera Nutrition 0.000 claims 1
- 240000008042 Zea mays Species 0.000 claims 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 235000005822 corn Nutrition 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
- A01N43/10—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with sulfur as the ring hetero atom
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
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Claims (36)
1. Композиция для борьбы с патогенными грибами, содержащая смеси по меньшей мере одного из соединений формулы I:
где
X представляет собой водород или C(O)R5;
Y представляет собой водород, C(O)R5 или Q;
Q представляет собой
R1 представляет собой CH2OCH3 или водород или алкил, где алкил необязательно замещен 0, 1 или несколькими R8;
R2 представляет собой метил;
R3 выбран из C(O)OCH3 или алкила, алкенила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8;
R4 выбран из алкила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8;
R5 представляет собой алкокси, необязательно замещенный 0, 1 или несколькими R8;
R6 выбран из водорода или алкокси, где алкокси необязательно замещен 0, 1 или несколькими R8;
R7 выбран из водорода, C(O)R9 или CH2OC(O)R9;
R8 выбран из водорода, алкила, арила, галогена, алкенила или фенокси, каждый из которых необязательно замещен 0, 1 или несколькими R10;
R9 выбран из алкила, алкокси или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8;
R10 выбран из алкила, арила, галогена, галогеналкила, галогенарила, алкенила или алкокси;
R11 выбран из водорода или метила.
2. Композиция по п.1, где X представляет собой водород, и Y представляет собой Q.
3. Композиция по п.2, где R7 представляет собой водород.
4. Композиция по п.3, где R6 представляет собой OCH3.
5. Композиция по п.4, где R1 и R11 независимо выбраны из водорода или метила.
6. Композиция по п.3, где R7 представляет собой C(O)R9 или CH2OC(O)R9.
7. Композиция по п.6, где R9 выбран из алкила, алкокси или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8.
8. Композиция по п.7, где R1 и R11 независимо выбраны из водорода или метила.
9. Композиция для борьбы с патогенными грибами, содержащая по меньшей мере одну из композиций по п.5 и ботанически приемлемый носитель.
10. Композиция для борьбы с патогенными грибами, содержащая по меньшей мере одну из композиций по п.8 и ботанически приемлемый носитель.
11. Композиция для борьбы с патогенными грибами, содержащая смеси по меньшей мере одной из композиций по п.5 и другого пестицида, включая фунгициды, инсектициды, нематоциды, майтициды, артроподициды, бактерициды и их комбинации.
12. Композиция для борьбы с патогенными грибами, содержащая смеси по меньшей мере одной из композиций по п.8 и другого пестицида, включая фунгициды, инсектициды, нематоциды, майтициды, артроподициды, бактерициды и их комбинации.
13. Композиции по п.1, где патогенный гриб представляет собой один из пятнистости листьев пшеницы (Zymoseptoria tritici), бурой ржавчины пшеницы (Puccinia triticina), желтой ржавчины (Puccinia striiformis), парши яблони (Venturia inaequalis), пузырчатой головни кукурузы (Ustilago maydis), мучнистой росы виноградной лозы (Uncinula necator), ожога ячменя (Rhynchosporium secalis), брунозе риса (Pyricularia oryzae), ржавчины сои (Phakopsora pachyrhizi), септориоза колосковой чешуи пшеницы (Leptosphaeria nodorum), мучнистой росы пшеницы (Blumeria graminis f. sp.tritici), мучнистой росы ячменя (Blumeria graminis f. sp. hordei), мучнистой росы тыквы (Erysiphe cichoracearum), антракноза тыквы (Colletotrichum lagenarium), пятнистости листьев свеклы (Cercospora beticola), бурой пятнистости томата (Alternaria solani) и сетчатой пятнистости ячменя (Pyrenophora teres).
14. Композиция по п.5 где патогенный гриб представляет собой один из пятнистости листьев пшеницы (Zymoseptoria tritici), бурой ржавчины пшеницы (Puccinia triticina) и ржавчины сои (Phakopsora pachyrhizi).
15. Композиция по п.8 где патогенный гриб представляет собой один из пятнистости листьев пшеницы (Zymoseptoria tritici), бурой ржавчины пшеницы (Puccinia triticina) и ржавчины сои (Phakopsora pachyrhizi).
16. Способ борьбы и предотвращения поражения грибами растения, включающий стадию: нанесения фунгицидно эффективного количества по меньшей мере одной из композиций по п.5 по меньшей мере на одно из следующего: на данное растение, площадь, прилегающую к данному растению, почву, адаптированную для поддержания роста данного растения, корень данного растения и листву данного растения.
17. Способ борьбы и предотвращения поражения грибами растения, включающий стадию: нанесения фунгицидно эффективного количества по меньшей мере одной из композиций по п.8 по меньшей мере на одно из следующего: на данное растение, площадь, прилегающую к данному растению, почву, адаптированную для поддержания роста данного растения, корень данного растения и листву данного растения.
18. Способ борьбы и предотвращения поражения грибами растения, включающий стадию: нанесения фунгицидно эффективного количества по меньшей мере одной из композиций по п.10 по меньшей мере на одно из следующего: на данное растение, площадь, прилегающую к данному растению, почву, адаптированную для поддержания роста данного растения, корень данного растения и листву данного растения.
19. Способ борьбы и предотвращения поражения грибами растения, включающий стадию: нанесения фунгицидно эффективного количества по меньшей мере одной из композиций по п.12 по меньшей мере на одно из следующего: на данное растение, площадь, прилегающую к данному растению, почву, адаптированную для поддержания роста данного растения, корень данного растения и листву данного растения.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462098089P | 2014-12-30 | 2014-12-30 | |
US201462098097P | 2014-12-30 | 2014-12-30 | |
US62/098,097 | 2014-12-30 | ||
US62/098,089 | 2014-12-30 | ||
US201562255152P | 2015-11-13 | 2015-11-13 | |
US201562255144P | 2015-11-13 | 2015-11-13 | |
US62/255,144 | 2015-11-13 | ||
US62/255,152 | 2015-11-13 | ||
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