[go: up one dir, main page]

RU2005139734A - HYDROGEL COMPOSITIONS MANIFESTING PHASE SEPARATION IN CONTACT WITH AQUEOUS MEDIA - Google Patents

HYDROGEL COMPOSITIONS MANIFESTING PHASE SEPARATION IN CONTACT WITH AQUEOUS MEDIA Download PDF

Info

Publication number
RU2005139734A
RU2005139734A RU2005139734/15A RU2005139734A RU2005139734A RU 2005139734 A RU2005139734 A RU 2005139734A RU 2005139734/15 A RU2005139734/15 A RU 2005139734/15A RU 2005139734 A RU2005139734 A RU 2005139734A RU 2005139734 A RU2005139734 A RU 2005139734A
Authority
RU
Russia
Prior art keywords
water
composition according
polymer
swellable
composition
Prior art date
Application number
RU2005139734/15A
Other languages
Russian (ru)
Other versions
RU2359707C2 (en
Inventor
Парминдер СИНГХ (US)
Парминдер СИНГХ
Гари В КЛИРИ (US)
Гари В КЛИРИ
Сри МУДУМБА (US)
Сри МУДУМБА
Михаил Майорович Фельдштейн (RU)
Михаил Майорович Фельдштейн
Данир Фанизович БАЙРАМОВ (RU)
Данир Фанизович БАЙРАМОВ
Original Assignee
Кориум Интернэшнл (Us)
Кориум Интернэшнл
Институт Нефтехимического Синтеза Имени А.В. Топчиева Ран (Ru)
Институт Нефтехимического Синтеза Имени А.В. Топчиева Ран
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кориум Интернэшнл (Us), Кориум Интернэшнл, Институт Нефтехимического Синтеза Имени А.В. Топчиева Ран (Ru), Институт Нефтехимического Синтеза Имени А.В. Топчиева Ран filed Critical Кориум Интернэшнл (Us)
Publication of RU2005139734A publication Critical patent/RU2005139734A/en
Application granted granted Critical
Publication of RU2359707C2 publication Critical patent/RU2359707C2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • A61C19/066—Bleaching devices; Whitening agent applicators for teeth, e.g. trays or strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/15—Compositions characterised by their physical properties
    • A61K6/16—Refractive index
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/20—Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22—Peroxides; Oxygen; Ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • A61K8/8176—Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L39/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions of derivatives of such polymers
    • C08L39/04—Homopolymers or copolymers of monomers containing heterocyclic rings having nitrogen as ring member
    • C08L39/06—Homopolymers or copolymers of N-vinyl-pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26—Optical properties
    • A61K2800/262—Transparent; Translucent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54—Polymers characterized by specific structures/properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54—Polymers characterized by specific structures/properties
    • A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
    • A61K2800/5422—Polymers characterized by specific structures/properties characterized by the charge nonionic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54—Polymers characterized by specific structures/properties
    • A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
    • A61K2800/5424—Polymers characterized by specific structures/properties characterized by the charge anionic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/10—Esters of organic acids, i.e. acylates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/03—Polymer mixtures characterised by other features containing three or more polymers in a blend
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2312/00—Crosslinking
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/02—Homopolymers or copolymers of acids; Metal or ammonium salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Dentistry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Cosmetics (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Claims (44)

1. Фаза-разделяющаяся, пленкообразующая композиция, содержащая1. Phase-separable, film-forming composition containing (a) первый набухающий в воде полимер, причем указанный полимер не растворяется в воде при рН менее примерно 5,5, или водорастворимый полимер,(a) a first water-swellable polymer, wherein said polymer is not soluble in water at a pH of less than about 5.5, or a water-soluble polymer, (b) смесь гидрофильного полимера и дополнительного олигомера, способного к образованию водородных связей с гидрофильным полимером,(b) a mixture of a hydrophilic polymer and an additional oligomer capable of forming hydrogen bonds with a hydrophilic polymer, (c) второй набухающий в воде полимер, причем указанный полимер не растворим в воде при всех значениях рН, и(c) a second water-swellable polymer, said polymer being insoluble in water at all pH values, and (d) необязательное активное вещество.(d) an optional active substance. 2. Композиция по п.1, в которой первый набухающий в воде нерастворимый в воде полимер представляет собой полимер или сополимер на основе акрилата.2. The composition according to claim 1, in which the first water-swellable water-insoluble polymer is an acrylate-based polymer or copolymer. 3. Композиция по п.2, в которой полимер или сополимер на основе акрилата выбирают из полимеров и сополимеров акриловой кислоты, метакриловой кислоты, метилакрилата, этилакрилата, метилметакрилата или этилметакрилата.3. The composition of claim 2, wherein the acrylate-based polymer or copolymer is selected from polymers and copolymers of acrylic acid, methacrylic acid, methyl acrylate, ethyl acrylate, methyl methacrylate or ethyl methacrylate. 4. Композиция по п.3, в которой сополимер на основе акрилата представляет собой сополимер метакриловой кислоты и метилметакрилата.4. The composition according to claim 3, in which the acrylate-based copolymer is a copolymer of methacrylic acid and methyl methacrylate. 5. Композиция по п.1, в которой водорастворимый полимер выбирают из водорастворимых полимеров на основе производных целлюлозы, поливинилового спирта, коллагена, встречающихся в природе полисахаридов.5. The composition according to claim 1, in which the water-soluble polymer is selected from water-soluble polymers based on cellulose derivatives, polyvinyl alcohol, collagen, naturally occurring polysaccharides. 6. Композиция по п.1, в которой второй набухающий в воде нерастворимый в воде полимер представляет собой эфир целлюлозы или полимер, или сополимер на основе акрилата.6. The composition according to claim 1, in which the second water-swellable water-insoluble polymer is a cellulose ether or a polymer or acrylate-based copolymer. 7. Композиция по п.6, в которой эфир целлюлозы включает, по меньшей мере, один целлюлозный полимер, содержащий мономерные звенья неэтерифицированной целлюлозы, мономерные звенья ацетата целлюлозы и либо мономерные звенья бутирата целлюлозы, либо мономерные звенья пропионата целлюлозы.7. The composition according to claim 6, in which the cellulose ether comprises at least one cellulose polymer containing monomer units of unesterified cellulose, monomer units of cellulose acetate and either monomer units of cellulose butyrate or monomer units of cellulose propionate. 8. Композиция по п.6, в которой полимер или сополимер на основе акрилата выбирают из полимеров и сополимеров акриловой кислоты, метакриловой кислоты, метилакрилата, этилакрилата, метилметакрилата или этилметакрилата.8. The composition according to claim 6, in which the polymer or copolymer based on acrylate is selected from polymers and copolymers of acrylic acid, methacrylic acid, methyl acrylate, ethyl acrylate, methyl methacrylate or ethyl methacrylate. 9. Композиция по п.8, в которой сополимер на основе акрилата представляет собой сополимер метакриловой кислоты и метилметакрилата.9. The composition of claim 8, in which the acrylate-based copolymer is a copolymer of methacrylic acid and methyl methacrylate. 10. Композиция по п.1, в которой весовое соотношение между первым набухающим в воде, нерастворимым в воде полимером и вторым набухающим в воде, нерастворимым в воде полимером находится в диапазоне приблизительно 1:3-3:1.10. The composition according to claim 1, in which the weight ratio between the first water-swellable, water-insoluble polymer and the second water-swellable, water-insoluble polymer is in the range of about 1: 3-3: 1. 11. Композиция по п.10, в которой соотношение находится в диапазоне приблизительно 1,5:1-2:1.11. The composition of claim 10, in which the ratio is in the range of approximately 1.5: 1-2: 1. 12. Композиция по п.1, в которой гидрофильный полимер выбирают из группы, включающей поли(N-виниллактамы), поли(N-виниламиды), поли(N-алкилакриламиды), полиакриловые кислоты, полиметакриловые кислоты, поливиниловый спирт, поливиниламин, и их сополимеры и смеси.12. The composition according to claim 1, in which the hydrophilic polymer is selected from the group comprising poly (N-vinyl lactams), poly (N-vinyl amides), poly (N-alkyl acrylamides), polyacrylic acids, polymethacrylic acids, polyvinyl alcohol, polyvinylamine, and their copolymers and mixtures. 13. Композиция по п.12, в которой гидрофильный полимер выбирают из группы, включающей поли(N-виниллактамы), поли(N-виниламиды), поли(N-алкилакриламиды), и их сополимеры и смеси.13. The composition according to item 12, in which the hydrophilic polymer is selected from the group comprising poly (N-vinyl lactams), poly (N-vinyl amides), poly (N-alkyl acrylamides), and copolymers and mixtures thereof. 14. Композиция по п.13, в которой гидрофильный полимер представляет собой поли(N-виниллактам) или гомополимер поли(N-виниллактама).14. The composition according to item 13, in which the hydrophilic polymer is a poly (N-vinyl lactam) or a homopolymer of poly (N-vinyl lactam). 15. Композиция по п.12, в которой поли(N-виниллактам) выбирают из группы, состоящей из поливинилпирролидона, поливинилкапролактама и их смесей.15. The composition of claim 12, wherein the poly (N-vinyl lactam) is selected from the group consisting of polyvinylpyrrolidone, polyvinylcaprolactam, and mixtures thereof. 16. Композиция по п.15, в которой поли(N-виниллактам) представляет собой поливинилпирролидон.16. The composition of claim 15, wherein the poly (N-vinyl lactam) is polyvinylpyrrolidone. 17. Композиция по п.12, в которой гидрофильный полимер имеет среднечисловую молекулярную массу в диапазоне приблизительно 10000-2000000.17. The composition according to item 12, in which the hydrophilic polymer has a number average molecular weight in the range of approximately 10000-2000000. 18. Композиция по п.1, в которой дополнительный олигомер имеет молекулярную массу в диапазоне приблизительно 45-800.18. The composition according to claim 1, in which the additional oligomer has a molecular weight in the range of about 45-800. 19. Композиция по п.18, в которой дополнительный олигомер имеет молекулярную массу в диапазоне приблизительно 45-600.19. The composition of claim 18, wherein the additional oligomer has a molecular weight in the range of about 45-600. 20. Композиция по п.18, в которой дополнительный олигомер выбирают из группы, состоящей из полиспиртов, мономерных и олигомерных алкиленгликолей, полиалкиленгликолей, полиалкиленгликолей с концевыми карбоксигруппами, полиалкиленгликолей с концевыми аминогруппами, неполных эфиров многоатомных спиртов, алкандиолов и дикарбоновых кислот.20. The composition according to p. 18, in which the additional oligomer is selected from the group consisting of polyalcohols, monomeric and oligomeric alkylene glycols, polyalkylene glycols, polyalkylene glycols with terminal carboxy groups, polyalkylene glycols with terminal amino groups, partial esters of polyhydric alcohols and alkanediols. 21. Композиция по п.20, в которой дополнительный олигомер выбирают из группы, состоящей из полиалкиленгликолей и полиалкиленгликолей с концевыми карбоксигруппами.21. The composition according to claim 20, in which the additional oligomer is selected from the group consisting of polyalkylene glycols and polyalkylene glycols with terminal carboxy groups. 22. Композиция по п.21, в которой дополнительный олигомер выбирают из группы, состоящей из полиэтиленгликолей и полиэтиленгликолей с концевыми карбоксигруппами.22. The composition according to item 21, in which the additional oligomer is selected from the group consisting of polyethylene glycols and polyethylene glycols with terminal carboxy groups. 23. Композиция по п.21, в которой дополнительный олигомер представляет собой полиэтиленгликоль.23. The composition according to item 21, in which the additional oligomer is a polyethylene glycol. 24. Композиция по п.1, в которой активное вещество присутствует и представляет собой отбеливающее вещество, выбранное из группы, состоящей из пероксидов, хлоритов металлов, перборатов, перкарбонатов, пероксикислот и их комбинаций.24. The composition according to claim 1, in which the active substance is present and is a whitening substance selected from the group consisting of peroxides, metal chlorites, perborates, percarbonates, peroxyacids and combinations thereof. 25. Композиция по п.24, в которой пероксид выбирают из группы, состоящей из пероксида водорода, пероксида кальция, пероксида карбамида и их смесей.25. The composition according to paragraph 24, in which the peroxide is selected from the group consisting of hydrogen peroxide, calcium peroxide, urea peroxide and mixtures thereof. 26. Композиция по п.25, в которой пероксид выбирают из группы, состоящей из диалкилпероксидов, диацилпероксидов, эфиров надкислот, пердикарбонатов, пероксидов кетонов и гидропероксидов.26. The composition according A.25, in which the peroxide is selected from the group consisting of dialkyl peroxides, diacyl peroxides, esters of peroxides, perdicarbonates, ketone peroxides and hydroperoxides. 27. Композиция по п.24, в которой хлорит металла выбирают из группы, состоящей из хлорита кальция, хлорита бария, хлорита магния, хлорита лития, хлорита натрия, хлорита калия, гипохлорита и диоксида хлора.27. The composition according to paragraph 24, in which the metal chlorite is selected from the group consisting of calcium chlorite, barium chlorite, magnesium chlorite, lithium chlorite, sodium chlorite, potassium chlorite, hypochlorite and chlorine dioxide. 28. Композиция по п.1, дополнительно содержащая, по меньшей мере, одну добавку, выбранную из группы, состоящей из флаворантов, подсластителей, наполнителей, консервантов, регуляторов рН, умягчителей, загустителей, окрашивающих веществ, пигментов, красителей, преломляющих частиц, флаворантов, подсластителей, стабилизаторов, добавок, обеспечивающих прочность, веществ для снижения клейкости, и усилителей проницаемости.28. The composition according to claim 1, additionally containing at least one additive selected from the group consisting of flavoring agents, sweeteners, fillers, preservatives, pH regulators, softeners, thickeners, coloring agents, pigments, dyes, refractive particles, flavoring agents , sweeteners, stabilizers, strength additives, tackifiers, and penetration enhancers. 29. Композиция по п.1, в которой относительные количества первого и второго набухающих в воде полимеров, гидрофильного полимера и дополнительного олигомера выбраны так, чтобы сделать композицию полупрозрачной.29. The composition according to claim 1, in which the relative amounts of the first and second water-swellable polymers, the hydrophilic polymer and the additional oligomer are selected so as to make the composition translucent. 30. Композиция по п.1, которая содержит приблизительно 0,1-60 вес.% активного вещества.30. The composition according to claim 1, which contains approximately 0.1-60 wt.% The active substance. 31. Композиция по п.1, которая содержит приблизительно 0,1-20 вес.% первого набухающего в воде полимера или водорастворимого полимера и второго набухающего в воде нерастворимого в воде полимера, и приблизительно 1-30 вес.% гидрофильного полимера.31. The composition according to claim 1, which contains approximately 0.1-20 wt.% The first water-swellable polymer or water-soluble polymer and the second water-swellable water-insoluble polymer, and about 1-30 wt.% Hydrophilic polymer. 32. Композиция по п.31, в которой дополнительный олигомер составляет приблизительно 1-85 вес.% от смеси гидрофильный полимер/дополнительный олигомер.32. The composition according to p, in which the additional oligomer is approximately 1-85 wt.% From the mixture of hydrophilic polymer / additional oligomer. 33. Композиция по п.1, которая содержит приблизительно 1-30 вес.% первого набухающего в воде полимера или водорастворимого полимера и второго набухающего в воде нерастворимого в воде полимера, и приблизительно 0,1-20 вес.% гидрофильного полимера.33. The composition according to claim 1, which contains approximately 1-30 wt.% The first water-swellable polymer or water-soluble polymer and the second water-swellable water-insoluble polymer, and about 0.1-20 wt.% Hydrophilic polymer. 34. Композиция по п.33, в которой дополнительный олигомер составляет приблизительно 1-85 вес.% от смеси гидрофильный полимер/дополнительный олигомер.34. The composition according to p, in which the additional oligomer is approximately 1-85 wt.% From the mixture of hydrophilic polymer / additional oligomer. 35. Композиция по п.1, которая содержит приблизительно 1-20 вес.% первого набухающего в воде полимера или водорастворимого полимера и второго набухающего в воде нерастворимого в воде полимера, и приблизительно 20-80 вес.% гидрофильного полимера.35. The composition according to claim 1, which contains approximately 1-20 wt.% The first water-swellable polymer or water-soluble polymer and the second water-swellable water-insoluble polymer, and about 20-80 wt.% Hydrophilic polymer. 36. Композиция по п.35, в которой дополнительный олигомер составляет приблизительно 10-80 вес.% от смеси гидрофильный полимер/дополнительный олигомер.36. The composition according to clause 35, in which the additional oligomer is approximately 10-80 wt.% From the mixture of hydrophilic polymer / additional oligomer. 37. Композиция по п.1, которая содержит приблизительно 20-80 вес.% первого набухающего в воде полимера или водорастворимого полимера и второго набухающего в воде нерастворимого в воде полимера, и приблизительно 1-20 вес.% гидрофильного полимера.37. The composition according to claim 1, which contains approximately 20-80 wt.% The first water-swellable polymer or water-soluble polymer and the second water-swellable water-insoluble polymer, and about 1-20 wt.% Hydrophilic polymer. 38. Композиция по п.37, в которой дополнительный олигомер составляет приблизительно 10-80 вес.% от смеси гидрофильный полимер/дополнительный олигомер.38. The composition according to clause 37, in which the additional oligomer is approximately 10-80 wt.% From the mixture of hydrophilic polymer / additional oligomer. 39. Способ отбеливания зубов, включающий нанесение композиции по п.1 на зубы, нуждающиеся в отбеливании, и удаление композиции, когда требуемая степень отбеливания достигнута.39. A method of whitening teeth, comprising applying the composition according to claim 1 to teeth in need of whitening, and removing the composition when the desired degree of whitening is achieved. 40. Способ по п.39, в котором требуемая степень отбеливания достигается после заданного периода времени.40. The method according to § 39, in which the desired degree of whitening is achieved after a predetermined period of time. 41. Способ по п.40, в котором заданный период времени составляет от приблизительно 10 мин до приблизительно 24 ч.41. The method according to p, in which a predetermined period of time is from about 10 minutes to about 24 hours 42. Способ по п.41, в котором заданный период времени составляет от приблизительно 10 мин до приблизительно 8 ч.42. The method according to paragraph 41, in which a predetermined period of time is from about 10 minutes to about 8 hours 43. Способ по п.42, в котором заданный период времени составляет от приблизительно 30 мин до приблизительно 1 ч.43. The method according to § 42, in which a predetermined period of time is from about 30 minutes to about 1 hour 44. Способ по п.39, в котором композицию можно носить в течение продолжительного периода времени.44. The method according to § 39, in which the composition can be worn for an extended period of time.
RU2005139734/15A 2003-05-19 2004-05-17 Hydrogel compositions showing separation of phases at contact with water medium RU2359707C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/442,020 US20030235549A1 (en) 2001-05-01 2003-05-19 Hydrogel compositions demonstrating phase separation on contact with aqueous media
US10/442,020 2003-05-19

Publications (2)

Publication Number Publication Date
RU2005139734A true RU2005139734A (en) 2006-06-27
RU2359707C2 RU2359707C2 (en) 2009-06-27

Family

ID=33476613

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2005139734/15A RU2359707C2 (en) 2003-05-19 2004-05-17 Hydrogel compositions showing separation of phases at contact with water medium

Country Status (11)

Country Link
US (1) US20030235549A1 (en)
EP (1) EP1633269B1 (en)
JP (1) JP2006528984A (en)
KR (1) KR20060015277A (en)
CN (1) CN1816312B (en)
AU (1) AU2004240628B2 (en)
CA (1) CA2526161C (en)
ES (1) ES2536715T3 (en)
IL (1) IL172030A0 (en)
RU (1) RU2359707C2 (en)
WO (1) WO2004103201A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2404739C2 (en) * 2004-07-29 2010-11-27 Колгейт-Палмолив Компани Oral composition with film-forming polymers

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
DE60233217D1 (en) 2001-05-01 2009-09-17 Corium Internat Inc HYDROGEL COMPOSITIONS
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US8206738B2 (en) * 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
EP2277556B1 (en) 2001-05-01 2016-04-20 A. V. Topchiev Institute of Petrochemical Synthesis Two-phase, water-absorbent bioadhesive composition
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US20050113510A1 (en) * 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
PT1539124T (en) 2002-09-05 2018-10-22 Vanderbilt Royalty Sub L P Compositions and kits for the removal of irritating compounds from bodily surfaces
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
AU2004261189A1 (en) * 2003-07-28 2005-02-10 Discus Dental, Llc. Compositions, methods, devices, and kits for maintaining or enhancing tooth whitening
CN1929819B (en) 2004-01-30 2012-02-29 考里安国际公司 Fast Dissolving Films for Active Agent Delivery
EP1725272A1 (en) * 2004-01-30 2006-11-29 Insense Limited Wound dressings comprising hydrated hydrogels and enzymes
CA2576158C (en) 2004-08-05 2020-10-27 Corium International, Inc. Adhesive composition
US20060045854A1 (en) 2004-08-27 2006-03-02 Lynette Zaidel Oral care composition with cross-linked polymer peroxide
US20060171906A1 (en) * 2004-12-21 2006-08-03 Corium International, Inc. Sustained release tooth whitening formulations and systems
US20060147394A1 (en) * 2004-12-30 2006-07-06 Ramachandra Shastry Tooth whitening composition containing cross-linked polymer-peroxides
US20070071695A1 (en) * 2005-09-27 2007-03-29 Colgate-Palmolive Company Single phase whitening dentifrice
US8568695B2 (en) * 2006-05-01 2013-10-29 Colgate-Palmolive Company Oral care composition with silicone composite
US9682256B2 (en) 2006-07-14 2017-06-20 Colgate-Palmolive Company Methods of making compositions comprising films
FR2933610B1 (en) * 2008-07-10 2013-04-05 Inovat Sarl OPAL COMPOSITION FOR THE TREATMENT OF DENTAL DISEASES
EP2313062A2 (en) 2008-07-15 2011-04-27 BASF Corporation Tooth polishing compositions and methods of tooth polishing without mechanical abrasion
BRPI0916446A2 (en) * 2008-07-15 2018-09-11 Basf Corp device, system, composition and method for delivering a substantially oxychlorine anion-free chlorine dioxide composition to a tissue
CA2730730A1 (en) * 2008-07-15 2010-01-21 Basf Corporation Non-cytotoxic chlorine dioxide fluids
US8784879B2 (en) 2009-01-14 2014-07-22 Corium International, Inc. Transdermal administration of tamsulosin
US20100196512A1 (en) 2009-02-04 2010-08-05 Basf Catalyst Llc Treatment of Non-Oral Biological Tissue with Chlorine Dioxide
US9101562B2 (en) 2010-01-31 2015-08-11 Basf Corporation Additives for chlorine dioxide-containing compositions
RU2429884C1 (en) * 2010-06-28 2011-09-27 Общество С Ограниченной Ответственностью "Акцент" Formulation for making antiseptic (versions) and method of use thereof
JP5829177B2 (en) * 2011-07-12 2015-12-09 富士フイルム株式会社 Curable composition for imprint, pattern forming method and pattern
RU2517142C2 (en) * 2012-04-27 2014-05-27 Общество с ограниченной ответственностью "Инновационные полимерные адгезивы" Hydrophilic pressure-sensitive bioadhesive with targeted adhesion towards teeth and dental care composition based thereon
US9956310B2 (en) * 2012-07-18 2018-05-01 Jeannette Martello Time indicator tampon
ES2739838T3 (en) 2012-09-11 2020-02-04 Slh Optimal Health Llc Dental cleaning composition
CN104837471A (en) 2012-12-14 2015-08-12 高露洁-棕榄公司 Peroxide-stable oral care compositions
JP6625985B2 (en) * 2013-09-11 2019-12-25 スリーエム イノベイティブ プロパティズ カンパニー Oral compositions, dental structures, and methods of delivering oral compositions
WO2016153792A1 (en) * 2015-03-25 2016-09-29 Arkema Inc. Colored organic peroxide compositions and methods for breaking hydraulic fracturing fluids
CN107428663A (en) * 2015-03-25 2017-12-01 阿科玛股份有限公司 Coloured organic peroxide composition
KR102102116B1 (en) * 2015-07-31 2020-04-20 가부시키가이샤 지씨 Composition for bleaching teeth
EP3534869B1 (en) 2016-12-20 2023-09-06 Colgate-Palmolive Company Oral care compositions
WO2018118498A1 (en) 2016-12-20 2018-06-28 Colgate-Palmolive Company Oral care composition
RU2742235C2 (en) 2016-12-20 2021-02-03 Колгейт-Палмолив Компани Oral care composition
MX389675B (en) 2017-01-12 2025-03-20 Colgate Palmolive Co ORAL CARE COMPOSITION FOR LONG-TERM PEROXIDE DELIVERY.
KR102004826B1 (en) * 2017-11-29 2019-07-29 오스템임플란트 주식회사 A compositon for maintaining tooth-whitening effect
CN114732942B (en) * 2022-04-12 2023-04-21 兰州大学 A kind of chlorine dioxide sustained-release liquid band-aid and preparation method thereof
CN115717034B (en) * 2022-11-25 2024-03-29 香港中文大学（深圳） Water-resistant adhesive based on hydrogen bond condensate and hydrophobic group, and preparation method and application thereof
CN118558067B (en) * 2024-04-30 2025-03-18 青岛大学 Air microorganism green capture membrane material and preparation method and application thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5770816A (en) * 1980-10-17 1982-05-01 Ono Pharmaceut Co Ltd Multilayered film preparation of prostagladin of prolonged action
US5279816A (en) * 1991-11-22 1994-01-18 Colgate-Palmolive Co. Oral composition having improved tooth whitening effect
CN1033364C (en) * 1992-10-26 1996-11-27 吴沈梁 Brightening agent for teeth
JP3022039B2 (en) * 1993-03-05 2000-03-15 サンスター株式会社 Oral composition for preventing tooth coloring
AU7245596A (en) * 1995-09-25 1997-04-17 Robert Eric Montgomery Tooth bleaching compositions
US5814304A (en) * 1996-08-02 1998-09-29 Colgate Palmolive Company Stable aqueous abrasive peroxide tooth whitening dentifrice
US5800832A (en) * 1996-10-18 1998-09-01 Virotex Corporation Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
US5879691A (en) * 1997-06-06 1999-03-09 The Procter & Gamble Company Delivery system for a tooth whitener using a strip of material having low flexural stiffness
ES2221173T3 (en) * 1997-06-06 2004-12-16 THE PROCTER & GAMBLE COMPANY ADMINISTRATION SYSTEM FOR A DENTAL WHITENER THAT USES A STRIP OF MATERIAL THAT HAS LOW FLEXION RIGIDITY.
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
ES2141050B1 (en) * 1998-03-20 2001-01-01 Biocosmetics Sl DENTAL WHITENING COMPOSITION.
CA2520986C (en) * 1998-09-25 2007-11-13 Warner-Lambert Company Physiological compatible film
HK1046633B (en) * 1999-07-02 2005-12-02 The Procter & Gamble Company Compositions comprising organosiloxane resins for delivering oral care substances
JP3682433B2 (en) * 2000-03-17 2005-08-10 エル・ジー ハウスホールド アンド ヘルスケア リミティッド Tooth whitening patch
JP4323797B2 (en) * 2000-07-07 2009-09-02 エイ．ブイ．トップチーブ インスティテュート オブ ペトロケミカル シンセシス Preparation of hydrophilic pressure sensitive adhesives with optimized adhesive properties
JP2002029949A (en) * 2000-07-19 2002-01-29 Lion Corp Composition for oral cavity
US20030044361A1 (en) * 2001-01-27 2003-03-06 Tianming Chen Enamel-safe tooth bleach and method for use
US6514484B2 (en) * 2001-03-19 2003-02-04 The Procter & Gamble Company Systems for delivering a cosmetic and/or therapeutic active to oral surfaces using an integral carrier
US8541021B2 (en) * 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
DE60233217D1 (en) * 2001-05-01 2009-09-17 Corium Internat Inc HYDROGEL COMPOSITIONS
US8840918B2 (en) * 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US6946142B2 (en) * 2001-06-23 2005-09-20 Lg Household & Healthcare Ltd. Multi-layer patches for teeth whitening
AU2002331146B2 (en) * 2001-08-17 2005-12-08 Smithkline Beecham P.L.C. Oral care substance delivery strip

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2404739C2 (en) * 2004-07-29 2010-11-27 Колгейт-Палмолив Компани Oral composition with film-forming polymers

Also Published As

Publication number Publication date
WO2004103201A2 (en) 2004-12-02
IL172030A0 (en) 2009-02-11
CA2526161A1 (en) 2004-12-02
RU2359707C2 (en) 2009-06-27
ES2536715T3 (en) 2015-05-27
JP2006528984A (en) 2006-12-28
EP1633269A4 (en) 2011-06-22
EP1633269A2 (en) 2006-03-15
AU2004240628A1 (en) 2004-12-02
CA2526161C (en) 2012-11-27
CN1816312A (en) 2006-08-09
EP1633269B1 (en) 2015-02-25
AU2004240628B2 (en) 2010-07-08
KR20060015277A (en) 2006-02-16
CN1816312B (en) 2013-04-03
US20030235549A1 (en) 2003-12-25
WO2004103201A3 (en) 2005-02-24

Similar Documents

Publication Publication Date Title
RU2005139734A (en) HYDROGEL COMPOSITIONS MANIFESTING PHASE SEPARATION IN CONTACT WITH AQUEOUS MEDIA
RU2005127587A (en) HYDROGEL COMPOSITIONS FOR TEETH WHITENING
CA2538727A1 (en) Hydrogel compositions with an erodible backing member
US6558654B2 (en) Composition and method for whitening teeth
AU2005319115B2 (en) Sustained release tooth whitening formulations and systems
RU2517142C2 (en) Hydrophilic pressure-sensitive bioadhesive with targeted adhesion towards teeth and dental care composition based thereon
US9089481B2 (en) Hydrogel compositions demonstrating phase separation on contact with aqueous media
US20240041719A1 (en) Teeth whitening compositions, kits, and systems
US20250000763A1 (en) Teeth whitening compositions, kits, and systems