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RU2003132877A - METHOD OF AUTOLOGICAL TRANSPLANTATION - Google Patents

METHOD OF AUTOLOGICAL TRANSPLANTATION Download PDF

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Publication number
RU2003132877A
RU2003132877A RU2003132877/15A RU2003132877A RU2003132877A RU 2003132877 A RU2003132877 A RU 2003132877A RU 2003132877/15 A RU2003132877/15 A RU 2003132877/15A RU 2003132877 A RU2003132877 A RU 2003132877A RU 2003132877 A RU2003132877 A RU 2003132877A
Authority
RU
Russia
Prior art keywords
product according
membrane
specified
specified membrane
cartilage
Prior art date
Application number
RU2003132877/15A
Other languages
Russian (ru)
Inventor
Бруно М ДЖИАННЕТТИ (DE)
Бруно М ДЖИАННЕТТИ
Сэмюэл С АСКУЛАЙ (CA)
Сэмюэл С АСКУЛАЙ
Ахмед ИДУРАИН (US)
Ахмед ИДУРАИН
Original Assignee
Вериген Трансплантацион Сервис Интернационал (Втси) Аг (De)
Вериген Трансплантацион Сервис Интернационал (Втси) Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Вериген Трансплантацион Сервис Интернационал (Втси) Аг (De), Вериген Трансплантацион Сервис Интернационал (Втси) Аг filed Critical Вериген Трансплантацион Сервис Интернационал (Втси) Аг (De)
Publication of RU2003132877A publication Critical patent/RU2003132877A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30756—Cartilage endoprostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3629—Intestinal tissue, e.g. small intestinal submucosa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/3654—Cartilage, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Claims (12)

1. Продукт, включающий мембрану, имеющую, по меньшей мере, один слой, обладающий пористой поверхностью и включающий ткань подслизистой кишечника, и клетки, прикрепившиеся к указанному слою.1. A product comprising a membrane having at least one layer having a porous surface and including submucosal tissue of the intestine, and cells attached to the specified layer. 2. Продукт по п.1, где указанные клетки представляют хондроциты.2. The product according to claim 1, where these cells are chondrocytes. 3. Продукт по п.1, где указанная мембрана не содержит клеток.3. The product according to claim 1, where the specified membrane does not contain cells. 4. Продукт по п.1, где указанная мембрана представляет коллаген.4. The product according to claim 1, where the specified membrane is collagen. 5. Продукт по п.1, где указанная мембрана представляет коллаген типа I и типа III.5. The product according to claim 1, where the specified membrane is collagen type I and type III. 6. Продукт по п.1, где указанная мембрана является рассасывающейся.6. The product according to claim 1, where the specified membrane is absorbable. 7. Продукт по п.1, где указанные хондроциты являются аутологичными.7. The product according to claim 1, where these chondrocytes are autologous. 8. Продукт по п.1, дополнительно включающий биосовместимую, прикрепляющуюся смежную указанную мембрану.8. The product according to claim 1, further comprising a biocompatible, affixing adjacent specified membrane. 9. Продукт по п.1, где указанная мембрана адаптирована для расположения над дефектом хряща сустава.9. The product according to claim 1, where the specified membrane is adapted for location above the defect of the cartilage of the joint. 10. Продукт по п.1, где указанная мембрана адаптирована для расположения в дефекте хряща сустава.10. The product according to claim 1, where the specified membrane is adapted for location in the defect of the cartilage of the joint. 11. Продукт по п.1, где указанная мембрана располагается над дефектом хряща сустава.11. The product according to claim 1, where the specified membrane is located above the defect of the cartilage of the joint. 12. Продукт по п.1, где указанная мембрана располагается в дефекте хряща сустава.12. The product according to claim 1, where the specified membrane is located in the defect of the cartilage of the joint.
RU2003132877/15A 2001-04-12 2002-04-12 METHOD OF AUTOLOGICAL TRANSPLANTATION RU2003132877A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28325301P 2001-04-12 2001-04-12
US60/283,253 2001-04-12

Publications (1)

Publication Number Publication Date
RU2003132877A true RU2003132877A (en) 2005-03-10

Family

ID=23085209

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2003132877/15A RU2003132877A (en) 2001-04-12 2002-04-12 METHOD OF AUTOLOGICAL TRANSPLANTATION

Country Status (14)

Country Link
EP (1) EP1390471A4 (en)
JP (1) JP2005502390A (en)
CN (1) CN1514877A (en)
BR (1) BR0208879A (en)
CA (1) CA2444004A1 (en)
CZ (1) CZ20033051A3 (en)
HU (1) HUP0401450A3 (en)
IL (1) IL158371A0 (en)
MX (1) MXPA03009312A (en)
NO (1) NO20034581L (en)
PL (1) PL367295A1 (en)
RU (1) RU2003132877A (en)
SK (1) SK13892003A3 (en)
WO (1) WO2002083878A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005221083A1 (en) * 2004-03-09 2005-09-22 Osteobiologics, Inc. Implant scaffold combined with autologous or allogenic tissue
US20060100138A1 (en) * 2004-11-10 2006-05-11 Olsen David R Implantable collagen compositions
DE102005030614B4 (en) 2005-06-30 2014-05-08 Biotissue Ag Cell-free graft, its use, process for its preparation, matrix thus produced with gel and process for the preparation of this matrix with gel
JP5225844B2 (en) * 2005-09-02 2013-07-03 エー・デー・ガイストリヒ・ゾーネ・アクチェンゲゼルシャフト・フュール・ヒェーミシェ・インダストリー Sheet of collagen membrane material to repair meniscal tear
CA2713118A1 (en) * 2008-02-29 2009-09-03 Interface Biotech A/S Biosynthetic cartilaginous matrix and methods for their production
EP2698173A1 (en) 2008-02-29 2014-02-19 Coloplast A/S Compositions and methods for augmentation and regeneration of living tissue in a subject
CA2878808A1 (en) * 2012-07-11 2014-01-16 Osiris Therapeutics, Inc. Methods of manufacturing cartilage products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5788625A (en) * 1996-04-05 1998-08-04 Depuy Orthopaedics, Inc. Method of making reconstructive SIS structure for cartilaginous elements in situ
US5759190A (en) * 1996-08-30 1998-06-02 Vts Holdings Limited Method and kit for autologous transplantation
US6171340B1 (en) * 1998-02-27 2001-01-09 Mcdowell Charles L. Method and device for regenerating cartilage in articulating joints

Also Published As

Publication number Publication date
CN1514877A (en) 2004-07-21
IL158371A0 (en) 2004-05-12
HUP0401450A3 (en) 2006-11-28
NO20034581D0 (en) 2003-10-10
EP1390471A4 (en) 2005-04-13
HUP0401450A2 (en) 2004-11-29
EP1390471A1 (en) 2004-02-25
MXPA03009312A (en) 2004-03-10
CZ20033051A3 (en) 2004-05-12
CA2444004A1 (en) 2002-10-24
BR0208879A (en) 2004-06-29
SK13892003A3 (en) 2004-07-07
WO2002083878A1 (en) 2002-10-24
PL367295A1 (en) 2005-02-21
NO20034581L (en) 2003-12-09
JP2005502390A (en) 2005-01-27

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Legal Events

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FA93 Acknowledgement of application withdrawn (no request for examination)

Effective date: 20020412