RU137735U1 - TWO-SECTION TUBE WITH SAMPLE AND COVER FOR CAPPING A TUBE (OPTIONS) - Google Patents

Abstract

1. A test tube with a collar located on the outside and protruding triangles with rounded gaps between them, with a graduation, an opaque marking field, with a lid for sealing the monolithic structure with a cap on which there are protrusions for picking up and Triangular protrusions are symmetrically located on the inside, with a hollow obturator with a thin flat surface for piercing with a needle, and with a sample intake, which consists of a monolithic cover-holder with an external cap for taking hands and a sampling tube, characterized in that a biconcave jumper is located inside the test tube, forming a monoblock of two separate sections with heights h and h, the closure cap has four flanges on the outside of the shutter, three of which are fastening and are evenly spaced, and the fourth flange protrudes to the lower edge of the obturator at half its own height to prevent the sample from spreading through the upper edge of the tube into the cavity that is located between the obturator and the cap m for taking by hands, and the channel is located in the center of the upper part of the lid - holder - the tube is inseparably integrated into the test tube lid with a hole of a polygonal section, where the diameter of the inscribed circle is equal to the diameter of the sampling tube, with an additional recess in one of the corners to balance the air flow, displaced from the test tube by the fluid coming through the sampling tube, and a seal with three mounting flanges located evenly on the outside. 2. The test tube according to claim 1, characterized in that

Description

The utility model relates to laboratory glassware, namely to test tubes, and can be used in chemical, physical, biological and clinical diagnostic laboratories for the collection, storage and transportation of samples.

The main field of application of a two-section tube with a probe and a cap for sealing the tube is used in medical practice, for example, for collecting human capillary blood in clinical diagnostic laboratories equipped with automatic and semi-automatic blood analyzers, storing and transporting biological fluid samples from the collection point to specialized laboratories .

Today, laboratory glassware, such as test tubes, are widely used in medical practice. For example, in the USA, Becton, Dickinson and company manufactures the Microtainer tube according to patent No. 5,288,466 of 02.22.1994, where the design is a tube made in the form of a monoblock with a rounded inner part and a tube for stability on a horizontal surface, with cap for corking tubes. A technical imperfection is that the tube does not contain the cap of the sample holder and the sample tube itself, and a spatula is made for collecting blood in the upper part of the tube, which leads to permanent contact of the reagent from the tube with the wound surface on a person’s finger and can lead to reagents entering the blood person. In the Russian Federation, the company Eiliton patented the device "Microtube for Capillary Blood (options)" No. 114277 of 11/09/2011. The proposed technical solution is structurally a cylindrical case in the first embodiment, on the lower end of which a removable closure cap with a closed upper end surface is mounted, and a spatula is made at the upper open end of the tube, also a removable capillary installed in the hole of the removable closure cap is included in the design, for fixing on the open end of the housing of the locking caps on the outer surface of the open end of the housing, a continuous annular support flange is made, and in the upper end second locking portion covers an annular groove cooperating with locking locking caps with the walls of the open end portion of the housing microtubes. The second option is characterized by the absence of a removable locking cap with a removable capillary. The disadvantages of the proposed design in both the first and second versions is the absence of structural elements for sealing the tube in the cap for capping the sample, which, if there is a blade located on the open end housing of the microtube, leads to leakage of blood under the cap of the tube when shaking, careless rotation, during inclined transportation, and also excludes the use of an automatic mixing of a blood sample.

The closest analogue to the claimed utility model (prototype) is the Microvette-200 test tube manufactured by Sarstedt AG & CO (Germany) according to patent No. 0517119 of 05/30/1992.

The prototype design is a tube for a small amount of blood, inserted into an external container, which is a tube with a protruding collar for installation in a centrifuge or other device, with two caps, one of which is designed to seal the tubes, and the other cap has a hole in a polygon with a sample probe installed in it.

For use in standard equipment, which is located in medical institutions, the test tube is made of two parts: the test tubes are of small volume and the tube, in size and configuration allowing reliable installation of the test tube with the tube in the equipment used, and comes complete with two caps (one for capping the sample, the second with a sample intake) worn on both sides. In this way, a combination of small capacity for small quantities of samples and a standard external size is achieved. At the same time, the drawback is the presence of two parts, which leads to an unnecessary step in the assembly of the tube, complicating the technological stage of assembly and causes both an additional consumption of material and an increase in the cost of the product. Another disadvantage of the prototype, as well as test tubes of well-known companies such as “Capiject” Terumo (USA), “Minicollect” Greiner Bio-one (Austria), “Impromini” (China), is the inability to use them to place two isolated samples for two different analyzes, although the physical volume of the product allows you to place two separate containers, without increasing the overall dimensions.

The objective of the claimed utility model is the creation of a two-section test tube with two insulated containers for placing two samples, a lid for capping the sample and a sample inlet for working with standard equipment, facilitating the work of personnel, simplifying the design and stage of the product manufacturing process, halving the volume of recyclable material from which test tubes are made, halving the cost of buying disposable material by using one two-section instead of two tubes onnoy.

The technical solution of a two-section test tube consists in placing standard tubes for different volumes of two insulated containers in their dimensions, which in volume correspond to the requirements for the sample volume for two different analyzes.

For a more complete disclosure of the utility model, a graphical description of the technical solution is presented in figures 1-6.

Figure 1 - two-sectional test tube in section;

Figure 2 is a two-section tube side view;

Figure 3 - cap for sealing tubes in a section;

Figure 4 is a two-sectional test tube in section with a probe;

5 is a sectional view of the holder cap;

6 is a cover holder, view A.

A two-section test tube (Fig. 1) is a tube (pos. 1) made of polymer or some other material with a biconcave jumper (pos. 2) located inside, forming a monoblock of two separate containers (two tubes) with a height h ₁ and h ₂ . On the outside of the two-section test tube, a protruding collar (pos. 3) is located on one side for installation in standard equipment, several protruding triangles (pos. 4) are symmetrically made over the collar with rounded gaps between them to facilitate removal of the cap.

On the outer surface of the two-section test tube (Fig. 2), graduation (pos. 5) can be applied to the internal volume of the test tube of one or both containers and an opaque field for marking the sample (pos. 6) with a writing object.

To close the two-section tube on both sides, caps are used to seal the tube (FIG. 3). The lid is a monolithic structure consisting of a hollow obturator (item 1), which has four flanges on the outside, three of which are fastening and are evenly distributed (item 2), and a cap for taking by hands (item 3), between which there is cavity to accommodate the edge of the tube (item 4). The cap for removing the cap by hand (pos. 3) is made with small protrusions on the outside to prevent slipping of the hand, and on the inside there are several symmetrically arranged triangular protrusions (pos. 5) to facilitate the removal of the cap from the tube. An additional fourth flange (pos. 6) is located on the lower part of the obturator, protruding halfway above the lower edge of the obturator to prevent the sample from spreading through the upper edge of the tube into the cavity, which is located between the obturator and the cap for taking it by hand (pos. 4). The inner flat surface of the obturator has a thinning (pos. 7), pierced with a needle to take an aliquot for analysis without opening the tube.

For sampling, a sample inlet is used (Fig. 4), which consists of a cover-holder (item 1) with a sample tube (item 2). Two samples are used to collect two samples into two isolated containers located in a two-section test tube. The sampling tube is a tube made of a polymer material. The length of the tube may vary depending on the volume of the sample to be taken.

For fastening the sampling tube, a cover holder is used (Fig. 5), which is a monolithic structure with a channel located in the center of the upper part (item 1) and a shutter with three mounting collars located evenly on the outside (item 2), fixing the lid inside the tube, and with an external cap for taking it by hand (key 3). The channel is an inseparably integrated tube with a polygonal opening in the test tube lid, where the diameter of the inscribed circle is equal to the diameter of the sampling tube, with an additional notch in one of the corners (pos. 4 - Fig. 6) to balance the air flow displaced from the tube coming through the sampling tube liquid. Between the obturator and the cap for taking hands there is a cavity (item 5) to accommodate the edge of the tube. The cap for removing the cap by hand (pos. 3) is made with small protrusions on the outside to prevent slipping of the hand, and on the inside there are several symmetrically arranged triangular protrusions to facilitate removal of the cap from the tube.

The constructive solution of placing two isolated containers in a two-section tube with a height of h ₁ and h ₂ , where they are located to each other in a ratio of h ₁ ≥h ₂ , depending on the required volume of two samples, allows using instead of two tubes for two different analyzes two-section test tube, placing in each of the isolated containers various reagents and samples, each of which will be examined according to its own method. In particular, for the study of capillary blood using a two-section tube made of a polymer material, which is preferable for the creation of single-use products in a sterile design and with the possibility of quick and safe disposal, each of the separate tube containers and sample intakes are pre-treated with anticoagulants to preserve human blood properties , various depending on the planned analyzes. A two-section test tube is suitable for applying reagents to the inner surface of containers and a sample in a finely divided, droplet, film form, and in liquid form, with a long shelf life, since the beads on the shutter (Fig. 3, item 2) ensure tightness.

A two-section test tube can be used with or without a probe.

When using a two-section tube without a sampling probe, the containers are first treated with the appropriate reagents (in the factory or laboratory conditions), then the samples are sequentially placed in one or two containers using an external standard device (for example, an automatic pipette-dispenser). The container is sealed with a lid (see Fig. 3), gently rotated several times to mix the blood sample and excipient, and incubated at room temperature. The second tank is filled similarly. It is allowed to use automatic shakers, mixers, and other devices for automatic mixing and homogenization of the sample, as well as centrifugation of the sealed tubes, since the design of the lid for sealing ensures tightness of the sample closure and prevents the sample from spreading over the edge of the tube even when repeatedly opening and closing the containers of a two-section tube.

If in the future the analysis of the sample is carried out on equipment that has a complete automatic sampling-piercer in the kit, the analysis can be performed without removing the cap to seal the tube, since the inner flat surface of the cap has a thinning for piercing with a needle (see Fig. 3, item 7). If the analysis is performed from a container with the cap removed (for example, on semi-automatic analyzers) and involves repeated capping of the sample, then due to the presence of an additional collar (Fig. 3, item 6) located in the lower part of the obturator, the sample is prevented from spreading through the upper edge of the tube into cavity (figure 3, position 4).

When using a two-section test tube with an inlet, the containers and inlets are first treated with the appropriate reagents (in the factory or laboratory conditions). When working with the built-in sampler (see Fig. 4), which is worn on the edge of the tube and held by the obturator, in particular, when taking blood from a person’s finger, the laboratory assistant must perform the following steps:

Wipe a finger with a cotton swab moistened with a disinfectant solution at the puncture site. Pierce your finger with a scarifier. Remove the first drop of blood with a dry swab.

Bring the capillary to the protruding drop of blood, holding a two-section tube with a sampling probe at an angle to the point of finger puncture from top to bottom. Fill the sample probe with freely protruding blood from the finger completely, pushing the finger as needed to form a drop of blood. Then turn the tube upright with the sample inlet up and allow the blood to drain into the tube. Due to the additional recess in one of the corners (Fig.6, pos.4) of the channel for attaching the sampling tube (pos.1, Fig.5), the air flow displaced from the test tube by the liquid entering through the sampling tube is balanced with atmospheric pressure, which allows the liquid to freely enter the tube, which is important, for example, in the analysis of human capillary blood, since the rapid movement of fluid prevents platelet aggregation and, as a result, increases the accuracy of the analysis.

Remove the sample inlet from the two-section tube. Seal the container with a lid (see Fig. 3), gently turn several times to mix the blood sample and excipient, and incubate at room temperature. The second tank is filled similarly. It is allowed to use automatic shakers, mixers, and other devices for automatic mixing and homogenization of the sample, as well as centrifugation in sealed tubes, since the design of the lid for sealing ensures the tightness of the sample closure and prevents the sample from spreading over the edge of the tube even when repeatedly opening and closing the containers of a two-section tube.

If in the future the analysis of the sample is carried out on equipment that has an automatic sampling-piercer in the kit, the analysis can be performed without removing the cover, since the inner flat surface of the cover for sealing the sample has a thinning for piercing with a needle (see Fig. 3, item 7). If the analysis is performed from a container with the cap removed (for example, on semi-automatic analyzers) and involves repeated capping of the sample, then due to the presence of an additional collar (Fig. 3, item 6) located in the lower part of the obturator, the sample is prevented from spreading through the upper edge of the tube into cavity (figure 3, position 4).

In the process of analysis, the laboratory assistant can put the two-section tube in a special tripod, and on a horizontal surface both in open and in closed form on either side.

The use of a two-section test tube with two insulated containers for placing two samples, a lid for capping the sample and a sampling probe allows working with standard equipment to expand the functionality by sequentially taking two immiscible samples of the same or different biological fluids, for example from one patient, in a shorter time and with less trauma, to halve the volume of recyclable material, reduce the cost of buying disposable material by half through the use of two tubes instead of a single two-section, as well as provide a higher level of safety for personnel in collecting, storing and transporting samples.

Claims (5)

1. A test tube with a collar located on the outside and protruding triangles with rounded gaps between them, with a graduation, an opaque marking field, with a lid for sealing the monolithic structure with a cap on which there are protrusions for picking up and Triangular protrusions are symmetrically located on the inside, with a hollow obturator with a thin flat surface for piercing with a needle, and with a sample intake, which consists of a monolithic cover-holder with the outer cap to capture the arms and the sample probe tube, characterized in that the inside tube is biconcave jumper forming monoblock of two separate sections with a height h ₁ and h ₂ for sealing cap has at the outer side of the obturator four bead, three of which fixing and are evenly spaced, and the fourth flange protrudes at the lower edge of the obturator by half its own height to prevent the sample from spreading through the upper edge of the tube into the cavity that is located between the obturator and the flask with a hand for collection, and at the sampler in the center of the upper part of the lid - holder there is a channel - a tube is inseparably integrated into the test tube lid with a polygonal hole, where the diameter of the inscribed circle is equal to the diameter of the sampling tube, with an additional recess in one of the corners to balance the air flow, displaced from the test tube by the fluid coming through the sampling tube, and a shutter with three mounting flanges located evenly on the outside. 2. The tube according to claim 1, characterized in that the isolated sections of the tube are located to each other in the ratio h ₁ ≥h ₂ . 3. The tube according to claim 1, characterized in that the graduation of the tube can be applied to one or both separate sections. 4. The test tube according to claim 1, characterized in that the sampling tube of the sampling probe is a tube made of a polymer material. 5. A test tube with a collar located on the outside and protruding triangles with rounded gaps between them, with a graduation, an opaque marking field, with a cap for capping a monolithic structure with a cap on which there are protrusions for picking up and Triangular protrusions are symmetrically located on the inside, with a hollow shutter with a thin flat surface for piercing with a needle, characterized in that a biconcave jumper is located inside the tube, about azuyuschaya monoblock of two separate sections with a height h ₁ and h ₂ for sealing cap has at the outer side of the obturator four bead, three of which fixing and arranged uniformly, and a fourth flange half own height protrudes beyond the lower edge of the obturator to prevent spreading of the sample through the upper edge of the tube into the cavity, which is located between the obturator and the cap for taking by hand.

Images