[go: up one dir, main page]

RS58141B1 - Anti-cxcr3 antitela - Google Patents

Anti-cxcr3 antitela

Info

Publication number
RS58141B1
RS58141B1 RS20181422A RSP20181422A RS58141B1 RS 58141 B1 RS58141 B1 RS 58141B1 RS 20181422 A RS20181422 A RS 20181422A RS P20181422 A RSP20181422 A RS P20181422A RS 58141 B1 RS58141 B1 RS 58141B1
Authority
RS
Serbia
Prior art keywords
cxcr3 antibodies
cxcr3
antibodies
Prior art date
Application number
RS20181422A
Other languages
English (en)
Inventor
Michele Youd
Jennifer Tedstone
Tracey Lodie
Karen B Carter
Timothy D Connors
Jason Robert Pinckney
Elizabeth Masterjohn
Ruiyin Chu
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of RS58141B1 publication Critical patent/RS58141B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RS20181422A 2012-01-20 2013-01-18 Anti-cxcr3 antitela RS58141B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261588936P 2012-01-20 2012-01-20
PCT/US2013/022280 WO2013109974A2 (en) 2012-01-20 2013-01-18 Anti-cxcr3 antibodies
EP13702548.2A EP2804878B1 (en) 2012-01-20 2013-01-18 Anti-cxcr3 antibodies

Publications (1)

Publication Number Publication Date
RS58141B1 true RS58141B1 (sr) 2019-02-28

Family

ID=47633576

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20181422A RS58141B1 (sr) 2012-01-20 2013-01-18 Anti-cxcr3 antitela

Country Status (27)

Country Link
US (4) US8865870B2 (sr)
EP (1) EP2804878B1 (sr)
JP (3) JP6352812B6 (sr)
KR (2) KR102073034B1 (sr)
CN (1) CN104507967B (sr)
AR (1) AR090056A1 (sr)
AU (1) AU2013209492B2 (sr)
BR (1) BR112014017814A8 (sr)
CA (1) CA2862222A1 (sr)
CY (1) CY1121335T1 (sr)
DK (1) DK2804878T3 (sr)
ES (1) ES2698606T3 (sr)
HK (1) HK1208684A1 (sr)
HR (1) HRP20181874T1 (sr)
HU (1) HUE041900T2 (sr)
IL (2) IL233694A0 (sr)
LT (1) LT2804878T (sr)
MX (1) MX359854B (sr)
PL (1) PL2804878T3 (sr)
PT (1) PT2804878T (sr)
RS (1) RS58141B1 (sr)
RU (1) RU2663141C2 (sr)
SG (2) SG11201406762QA (sr)
SI (1) SI2804878T1 (sr)
TW (1) TWI596112B (sr)
UY (1) UY34582A (sr)
WO (1) WO2013109974A2 (sr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9592289B2 (en) 2012-03-26 2017-03-14 Sanofi Stable IgG4 based binding agent formulations
MA40526A (fr) 2014-08-22 2017-06-28 Sorrento Therapeutics Inc Protéines de fixation antigénique fixant le cxcr3
WO2017075432A2 (en) * 2015-10-29 2017-05-04 Alector Llc Anti-siglec-9 antibodies and methods of use thereof
WO2017205377A2 (en) * 2016-05-23 2017-11-30 New York University Compositions and methods for antibodies targeting staphylococcal leukotoxins
KR20190095942A (ko) * 2016-12-22 2019-08-16 사노피 백반증의 치료를 위한 항-인간 cxcr3 항체
US20180244787A1 (en) 2016-12-22 2018-08-30 Sanofi Anti-human cxcr3 antibodies for treatment of vitiligo
UY37544A (es) 2016-12-22 2018-07-31 Sanofi Sa Anticuerpos humanizados contra cxcr3 con actividad mermadora y métodos de uso de los mismos
EP3752134B1 (en) * 2018-02-16 2024-12-04 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for treating vitiligo
CN113573728A (zh) 2018-11-14 2021-10-29 安驰肿瘤公司 治疗性SIRPα抗体
TWI859420B (zh) 2020-02-26 2024-10-21 美商維爾生物科技股份有限公司 抗sars-cov-2抗體及使用其之方法
US20230279108A1 (en) * 2020-04-30 2023-09-07 Arch Oncology, Inc. Therapeutic sirp-alpha antibodies
US20240101673A1 (en) 2021-02-03 2024-03-28 Mozart Therapeutics, Inc. Binding agents and methods of using the same
AU2022229356A1 (en) * 2021-03-02 2023-08-10 Novarock Biotherapeutics, Ltd. Antibodies against claudin-6 and uses thereof
KR20240043784A (ko) * 2021-08-09 2024-04-03 메르크 파텐트 게엠베하 염증유발성 시토카인의 방출로부터 t 세포-매개 종양 세포독성을 디커플링시키는 단백질
WO2023076876A1 (en) 2021-10-26 2023-05-04 Mozart Therapeutics, Inc. Modulation of immune responses to viral vectors
WO2024052445A1 (en) 2022-09-09 2024-03-14 Idorsia Pharmaceuticals Ltd Pharmaceutical combination comprising an anti-cd3 antibody and a cxcr3 antagonist

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US565332A (en) 1896-08-04 Toy for making soap-bubbles
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
EP1186660A3 (fr) 1985-03-30 2002-03-20 KAUFFMAN, Stuart A. Procédé d'obtension d'ADN, ARN, peptides, polypeptides ou protéines, par une technique de recombination d'ADN
US5618920A (en) 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5763192A (en) 1986-11-20 1998-06-09 Ixsys, Incorporated Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
DE69233482T2 (de) 1991-05-17 2006-01-12 Merck & Co., Inc. Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
EP0571613B1 (en) 1991-12-13 2003-09-17 Xoma Corporation Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
ES2162823T5 (es) 1992-08-21 2010-08-09 Vrije Universiteit Brussel Inmunoglobulinas desprovistas de cadenas ligeras.
US6005079A (en) 1992-08-21 1999-12-21 Vrije Universiteit Brussels Immunoglobulins devoid of light chains
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
AU6796094A (en) 1993-04-29 1994-11-21 Raymond Hamers Production of antibodies or (functionalized) fragments thereof derived from heavy chain immunoglobulins of (camelidae)
JP2826272B2 (ja) 1993-10-26 1998-11-18 タイガースポリマー株式会社 中空樹脂成形品の製造装置及び製造方法
US5565352A (en) 1993-11-24 1996-10-15 Arch Development Corporation Deubiquitinating enzyme: compositions and methods
US5714352A (en) 1996-03-20 1998-02-03 Xenotech Incorporated Directed switch-mediated DNA recombination
DE69737656T2 (de) * 1996-09-10 2008-01-03 Theodor Kocher Institut Cxcr3 chemokine rezeptor, antikoerper, nukleinsaeure und deren verfahren zur anwendung
US6140064A (en) * 1996-09-10 2000-10-31 Theodor-Kocher Institute Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3
US7115396B2 (en) 1998-12-10 2006-10-03 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
WO2001072334A2 (en) * 2000-03-27 2001-10-04 Corixa Corporation Methods for treating disease with antibodies to cxcr3
US7118915B2 (en) 2001-09-27 2006-10-10 Pieris Proteolab Ag Muteins of apolipoprotein D
KR20060106631A (ko) * 2003-06-30 2006-10-12 바이오-테크널러지 제너럴 (이스라엘) 리미티드 항체 및 이의 용도
EP1631315B1 (en) 2003-09-24 2014-07-30 Millennium Pharmaceuticals, Inc. Antibodies which bind human cxcr3
ES2384176T3 (es) * 2004-03-23 2012-07-02 Eli Lilly & Company Anticuerpos anti-miostatina
JP2008509666A (ja) 2004-08-11 2008-04-03 トルビオン・ファーマシューティカルズ・インコーポレイテッド 結合ドメイン融合タンパク質
EP2007808A4 (en) 2006-04-14 2010-07-21 Trubion Pharmaceuticals Inc BINDING PROTEINS HAVING AN IMMUNOGLOBULIN HINGE AND FC REGIONS WITH ALTERED EFFECTOR FUNCTIONS
WO2008094942A2 (en) 2007-02-01 2008-08-07 Teva Biopharmaceuticals Usa, Inc. Humanized antibodies against cxcr3
BRPI0815983A2 (pt) 2007-08-29 2018-05-22 Sanofi Aventis anticorpos anti-cxcr5 humanizados, derivados dos mesmos e seus usos
WO2010056907A2 (en) 2008-11-12 2010-05-20 The Scripps Research Institute Compounds that induce pancreatic beta-cell expansion
WO2010103517A1 (en) * 2009-03-12 2010-09-16 Rappaport Family Institute For Research In The Medical Sciences Soluble compositions for the treatment of cxcr3-ligand associated diseases
CA2789963C (en) * 2010-02-26 2019-09-03 Bioarctic Neuroscience Ab Protofibril-binding antibodies and their use in therapeutic and diagnostic methods for parkinson's disease, dementia with lewy bodies and other alpha-synucleinopathies

Also Published As

Publication number Publication date
US20130251733A1 (en) 2013-09-26
SG10201700735PA (en) 2017-02-27
IL233694A0 (en) 2014-09-30
US20140377806A1 (en) 2014-12-25
PT2804878T (pt) 2018-11-29
JP2018166506A (ja) 2018-11-01
TW201335188A (zh) 2013-09-01
JP2020072715A (ja) 2020-05-14
SI2804878T1 (sl) 2018-12-31
HRP20181874T1 (hr) 2019-01-11
SG11201406762QA (en) 2014-11-27
US8865870B2 (en) 2014-10-21
WO2013109974A2 (en) 2013-07-25
PL2804878T3 (pl) 2019-03-29
DK2804878T3 (en) 2018-12-17
JP6646100B2 (ja) 2020-02-14
RU2014134043A (ru) 2016-03-20
US20190119391A1 (en) 2019-04-25
RU2663141C2 (ru) 2018-08-01
AU2013209492A1 (en) 2014-08-14
ES2698606T3 (es) 2019-02-05
UY34582A (es) 2013-09-02
EP2804878B1 (en) 2018-08-22
MX359854B (es) 2018-10-12
LT2804878T (lt) 2018-12-10
EP2804878A2 (en) 2014-11-26
HK1208684A1 (en) 2016-03-11
BR112014017814A8 (pt) 2017-07-11
KR20140116525A (ko) 2014-10-02
TWI596112B (zh) 2017-08-21
BR112014017814A2 (sr) 2017-06-20
KR102073034B1 (ko) 2020-02-05
MX2014008728A (es) 2015-07-06
JP2015506945A (ja) 2015-03-05
KR20200014441A (ko) 2020-02-10
CN104507967B (zh) 2018-10-12
CA2862222A1 (en) 2013-07-25
CN104507967A (zh) 2015-04-08
AR090056A1 (es) 2014-10-15
US9765144B2 (en) 2017-09-19
CY1121335T1 (el) 2020-05-29
AU2013209492B2 (en) 2018-02-08
IL271697A (en) 2020-02-27
WO2013109974A3 (en) 2013-11-07
JP6352812B2 (ja) 2018-07-04
JP6352812B6 (ja) 2018-08-08
US20180086838A1 (en) 2018-03-29
HUE041900T2 (hu) 2019-06-28

Similar Documents

Publication Publication Date Title
IL293362B1 (en) Broad-spectrum neutralizing antibodies against the AIDS virus
IL271697A (en) Antibodies against CXCR3
IL264558A (en) Anti–il–23p19 antibodies
HK1204571A1 (en) Protease-regulated antibodies
ZA201407509B (en) Anti-fcrn antibodies
HK1210192A1 (en) Anti-siglec-15 antibodies siglec-15
HK1210186A1 (en) Anti-h7cr antibodies h7cr
PL2935330T3 (pl) Przeciwciała przeciw notch3
EP2804876A4 (en) NEW ANTIBODIES
IL235188A0 (en) Antibodies against c-pdgf
GB201209584D0 (en) Modified antibodies