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RS20060195A - Imidazopyridine-derivatives as inducible no-synthase inhibitors - Google Patents

Imidazopyridine-derivatives as inducible no-synthase inhibitors

Info

Publication number
RS20060195A
RS20060195A YUP-2006/0195A YUP20060195A RS20060195A RS 20060195 A RS20060195 A RS 20060195A YU P20060195 A YUP20060195 A YU P20060195A RS 20060195 A RS20060195 A RS 20060195A
Authority
RS
Serbia
Prior art keywords
imidazopyridine
inducible
derivatives
synthase inhibitors
inhibitors
Prior art date
Application number
YUP-2006/0195A
Other languages
English (en)
Inventor
Thomas Martin
Degenhard Marx
Rainer Boer
Thomas Fuchss
Andreas Strub
Manfrid Eltze
Martin Lehner
Wolf-Ruediger Ulrich
Original Assignee
Altana Pharma Ag.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag., filed Critical Altana Pharma Ag.,
Publication of RS20060195A publication Critical patent/RS20060195A/sr

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
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    • A—HUMAN NECESSITIES
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Psychology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)

Abstract

Jedinjenja formule (I), u kojoj R1, R2, Het1 i A, imaju značenja data u opisu jesu novi efikasni inhibitori inducibilne iNOS-e.
YUP-2006/0195A 2003-10-01 2004-09-30 Imidazopyridine-derivatives as inducible no-synthase inhibitors RS20060195A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03022064 2003-10-01
PCT/EP2004/052376 WO2005030769A1 (en) 2003-10-01 2004-09-30 Imidazopyridine-derivatives as inducible no-synthase inhibitors

Publications (1)

Publication Number Publication Date
RS20060195A true RS20060195A (en) 2008-08-07

Family

ID=34384572

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-2006/0195A RS20060195A (en) 2003-10-01 2004-09-30 Imidazopyridine-derivatives as inducible no-synthase inhibitors

Country Status (17)

Country Link
US (1) US20080125460A1 (sr)
EP (1) EP1673371B1 (sr)
JP (1) JP2007507465A (sr)
KR (1) KR20060092222A (sr)
CN (1) CN1856494A (sr)
AT (1) ATE403655T1 (sr)
AU (1) AU2004276013A1 (sr)
BR (1) BRPI0414873A (sr)
CA (1) CA2540242A1 (sr)
DE (1) DE602004015628D1 (sr)
EA (1) EA200600609A1 (sr)
IL (1) IL173809A0 (sr)
MX (1) MXPA06003554A (sr)
NO (1) NO20061316L (sr)
RS (1) RS20060195A (sr)
WO (1) WO2005030769A1 (sr)
ZA (1) ZA200601552B (sr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2540083A1 (en) 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inductible no-synthase inhibitors
CA2540239A1 (en) 2003-10-01 2005-04-07 Altana Pharma Ag Imidazo(4,5-b)pyridine-derivatives as inducible no-synthase inhibitors
EA200600601A1 (ru) 2003-10-01 2006-10-27 Алтана Фарма Аг Производные аминопиридина в качестве ингибиторов индуцируемой no-синтазы
JP2007507466A (ja) 2003-10-01 2007-03-29 アルタナ　ファルマ　アクチエンゲゼルシャフト 誘導性ｎｏシンターゼ阻害剤としてのイミダゾピリジン誘導体
WO2009029625A1 (en) * 2007-08-27 2009-03-05 Kalypsys, Inc. 4- [heterocyclyl-methyl] -8-fluoro-quinolin-2-ones useful as nitric oxide synthase inhibitors
EP2576540B1 (en) * 2010-05-26 2019-09-04 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof
WO2014085284A1 (en) * 2012-11-29 2014-06-05 Sunovion Pharmaceuticals Inc. Triazolo-pyrazine derivatives useful in the treatment of disorders of the central nervous system
GB201512635D0 (en) 2015-07-17 2015-08-26 Ucl Business Plc Uses of therapeutic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
AUPP873799A0 (en) * 1999-02-17 1999-03-11 Fujisawa Pharmaceutical Co., Ltd. Pyridine compounds
NZ535959A (en) * 2002-03-27 2006-05-26 Altana Pharma Ag Novel alkoxypyridine-derivatives as selective inhibitors of inducible nitric oxidase synthase NOS

Also Published As

Publication number Publication date
EP1673371B1 (en) 2008-08-06
MXPA06003554A (es) 2006-06-05
US20080125460A1 (en) 2008-05-29
NO20061316L (no) 2006-03-23
ATE403655T1 (de) 2008-08-15
IL173809A0 (en) 2006-07-05
CN1856494A (zh) 2006-11-01
BRPI0414873A (pt) 2006-12-12
WO2005030769A1 (en) 2005-04-07
AU2004276013A1 (en) 2005-04-07
EA200600609A1 (ru) 2006-10-27
DE602004015628D1 (de) 2008-09-18
JP2007507465A (ja) 2007-03-29
CA2540242A1 (en) 2005-04-07
EP1673371A1 (en) 2006-06-28
ZA200601552B (en) 2007-04-25
KR20060092222A (ko) 2006-08-22

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