RO86511A - Procedeu pentru prepararea unor beta-lactame - Google Patents

Procedeu pentru prepararea unor beta-lactame

Info

Publication number: RO86511A
Authority: RO; Romania
Prior art keywords: lactames; beta; preparation
Prior art date: 1982-08-04

Application number

RO83111814A

Other languages

English (en)

French (fr)

Other versions

RO86511B (ro

Inventor

Hermann Breuer

Henner Straub

Original Assignee

Er Squibb And Sons Inc,Us

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-08-04

Filing date

1983-08-04

Publication date

1985-03-15

1983-08-04 Application filed by Er Squibb And Sons Inc,Us filed Critical Er Squibb And Sons Inc,Us

1985-03-15 Publication of RO86511A publication Critical patent/RO86511A/ro

1985-03-31 Publication of RO86511B publication Critical patent/RO86511B/ro

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Cephalosporin Compounds (AREA)

RO111814A 1982-08-04 1983-08-04 Procedeu pentru prepararea unor beta-lactame RO86511B (ro)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US40494582A	1982-08-04	1982-08-04

Publications (2)

Publication Number	Publication Date
RO86511A true RO86511A (ro)	1985-03-15
RO86511B RO86511B (ro)	1985-03-31

Family

ID=23601669

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
RO111814A RO86511B (ro)	1982-08-04	1983-08-04	Procedeu pentru prepararea unor beta-lactame

Country Status (33)

Country	Link
US (1)	US4939253A (ro)
JP (1)	JPS5993046A (ro)
KR (1)	KR900001211B1 (ro)
AR (1)	AR241158A1 (ro)
AT (1)	AT382367B (ro)
AU (1)	AU568086B2 (ro)
BE (1)	BE897466A (ro)
CH (1)	CH655309A5 (ro)
CS (4)	CS243499B2 (ro)
DD (1)	DD213919A5 (ro)
DE (1)	DE3328047A1 (ro)
DK (1)	DK354683A (ro)
ES (1)	ES524698A0 (ro)
FI (1)	FI832675A (ro)
FR (1)	FR2531427A1 (ro)
GB (1)	GB2125794B (ro)
GR (1)	GR79368B (ro)
HU (1)	HU191058B (ro)
IE (1)	IE55839B1 (ro)
IL (1)	IL69381A (ro)
IN (1)	IN160955B (ro)
IT (1)	IT1224129B (ro)
LU (1)	LU84947A1 (ro)
NL (1)	NL8302746A (ro)
NO (1)	NO832801L (ro)
NZ (1)	NZ205111A (ro)
PL (3)	PL257441A1 (ro)
PT (1)	PT77155B (ro)
RO (1)	RO86511B (ro)
SE (1)	SE8304256L (ro)
SU (1)	SU1329617A3 (ro)
YU (1)	YU43324B (ro)
ZA (1)	ZA835470B (ro)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4939253A (en) *	1982-08-04	1990-07-03	E. R. Squibb & Sons, Inc.	2-oxoazetidin-1-yloxy acetic acids and analogs
US4548747A (en) *	1983-05-02	1985-10-22	E. R. Squibb & Sons, Inc.	3-Acylamino-1-sulfonylaminocarbonylmethoxy-2-azetidinones
ATE39356T1 (de) *	1983-05-31	1989-01-15	Squibb & Sons Inc	(((3-acylamino-2-oxo-1-azetidinyl)oxy>methyl>phosphins\|ure.
US4534896A (en) *	1983-06-13	1985-08-13	E. R. Squibb & Sons, Inc.	3-Acylamino-2-oxoazetidine-1-(β-oxopropionic acid)
US4548751A (en) *	1983-08-03	1985-10-22	E. R. Squibb & Sons, Inc.	(2-Oxo-1-azetidinyloxy)-2-propenoic acid
AU581180B2 (en) *	1983-08-26	1989-02-16	E.R. Squibb & Sons, Inc.	1-(1h-tetrazol-5-ylalkoxy)-2-azetidinones
CA1243679A (en) *	1983-09-14	1988-10-25	Henner Straub	3-ACYLAMINO-2-OXO-1-AZETIDINYL-.beta.-OXYPROPIONATES
EP0135194A1 (en) *	1983-09-16	1985-03-27	Takeda Chemical Industries, Ltd.	Azetidinones and their production
WO1985004876A1 (en) *	1984-04-24	1985-11-07	Takeda Chemical Industries, Ltd.	2-azetidinone derivatives and process for their preparation
US4559335A (en) *	1983-10-03	1985-12-17	E. R. Squibb & Sons, Inc.	3-Acylamino-1-carboxymethyloxy (or thio) carbonyl-2-azetidinones
US4576749A (en) *	1983-10-03	1986-03-18	E. R. Squibb & Sons, Inc.	3-Acylamino-1-carboxymethylaminocarbonyl-2-azetidinones
US4551277A (en) *	1983-11-09	1985-11-05	E. R. Squibb & Sons, Inc.	4-(3-Acylamino-2-oxo-1-azetidinyl)-4-oxo-2-butenoic acid
US4581170A (en) *	1984-08-03	1986-04-08	E. R. Squibb & Sons, Inc.	N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones
EG18314A (en) *	1985-09-26	1993-02-28	Squibb & Sons Inc	Process for preparing of 2-oxo-1((substituted sulfonyl)amino)carbonyl)-azitidines
US5112968A (en) *	1989-07-28	1992-05-12	E. R. Squibb & Sons, Inc.	Monobactam hydrazide derivatives
JP2008520686A (ja) *	2004-11-17	2008-06-19	スミスクライン・ビーチャム・コーポレイション	新規な抗菌化合物の使用
EP2308874B1 (en) *	2005-12-07	2013-01-23	Basilea Pharmaceutica AG	Bridged monobactams useful as beta-lactamase inhibitors
WO2014164526A1 (en) *	2013-03-13	2014-10-09	Rempex Pharmaceuticals, Inc.	Oxamazin antibiotics
US20140275007A1 (en) *	2013-03-14	2014-09-18	Rempex Pharmaceuticals, Inc.	Oxamazin antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ196202A (en) *	1980-02-07	1984-07-31	Squibb & Sons Inc	Beta-lactam antibiotics (of azetidine-sulphonic acid type)
EP0048953B1 (en) *	1980-09-29	1988-03-09	E.R. Squibb & Sons, Inc.	Beta-lactam antibiotics
US4337197A (en) *	1980-10-31	1982-06-29	E. R. Squibb & Sons, Inc.	O-sulfated β-lactam hydroxamic acids and intermediates
WO1982001873A1 (en) *	1980-12-05	1982-06-10	Takeda Chemical Industries Ltd	1-sulfo-2-oxoazetidine derivatives and process for their preparation
US4939253A (en) *	1982-08-04	1990-07-03	E. R. Squibb & Sons, Inc.	2-oxoazetidin-1-yloxy acetic acids and analogs

1983
- 1983-07-21 US US06/515,727 patent/US4939253A/en not_active Expired - Fee Related
- 1983-07-22 FI FI832675A patent/FI832675A/fi not_active Application Discontinuation
- 1983-07-22 HU HU832602A patent/HU191058B/hu not_active IP Right Cessation
- 1983-07-26 ZA ZA835470A patent/ZA835470B/xx unknown
- 1983-07-28 GR GR72076A patent/GR79368B/el unknown
- 1983-07-29 GB GB08320497A patent/GB2125794B/en not_active Expired
- 1983-08-01 IL IL69381A patent/IL69381A/xx unknown
- 1983-08-02 NZ NZ205111A patent/NZ205111A/en unknown
- 1983-08-03 AU AU17556/83A patent/AU568086B2/en not_active Ceased
- 1983-08-03 CS CS85268A patent/CS243499B2/cs unknown
- 1983-08-03 ES ES524698A patent/ES524698A0/es active Granted
- 1983-08-03 CS CS83267A patent/CS26783A2/cs unknown
- 1983-08-03 SE SE8304256A patent/SE8304256L/xx not_active Application Discontinuation
- 1983-08-03 CS CS85267A patent/CS243498B2/cs unknown
- 1983-08-03 NO NO832801A patent/NO832801L/no unknown
- 1983-08-03 CS CS835759A patent/CS243474B2/cs unknown
- 1983-08-03 KR KR1019830003626A patent/KR900001211B1/ko not_active IP Right Cessation
- 1983-08-03 AT AT0281283A patent/AT382367B/de not_active IP Right Cessation
- 1983-08-03 SU SU833635150A patent/SU1329617A3/ru active
- 1983-08-03 IE IE1830/83A patent/IE55839B1/en not_active IP Right Cessation
- 1983-08-03 DE DE19833328047 patent/DE3328047A1/de not_active Ceased
- 1983-08-03 NL NL8302746A patent/NL8302746A/nl unknown
- 1983-08-03 PT PT77155A patent/PT77155B/pt not_active IP Right Cessation
- 1983-08-03 DK DK354683A patent/DK354683A/da not_active Application Discontinuation
- 1983-08-04 FR FR8312862A patent/FR2531427A1/fr active Granted
- 1983-08-04 IT IT22430/83A patent/IT1224129B/it active
- 1983-08-04 CH CH4244/83A patent/CH655309A5/fr not_active IP Right Cessation
- 1983-08-04 DD DD83253715A patent/DD213919A5/de not_active IP Right Cessation
- 1983-08-04 AR AR293815A patent/AR241158A1/es active
- 1983-08-04 BE BE0/211304A patent/BE897466A/fr not_active IP Right Cessation
- 1983-08-04 RO RO111814A patent/RO86511B/ro unknown
- 1983-08-04 PL PL25744183A patent/PL257441A1/xx unknown
- 1983-08-04 JP JP58143603A patent/JPS5993046A/ja active Pending
- 1983-08-04 YU YU1627/83A patent/YU43324B/xx unknown
- 1983-08-04 LU LU84947A patent/LU84947A1/fr unknown
- 1983-08-04 PL PL25744083A patent/PL257440A1/xx unknown
- 1983-08-04 PL PL24330883A patent/PL243308A1/xx unknown
- 1983-08-11 IN IN525/DEL/83A patent/IN160955B/en unknown

Also Published As

Publication number	Publication date
IL69381A (en)	1987-07-31
PL257441A1 (en)	1986-10-07
FI832675A (fi)	1984-02-05
CS26785A2 (en)	1985-08-15
JPS5993046A (ja)	1984-05-29
AU568086B2 (en)	1987-12-17
LU84947A1 (fr)	1984-03-23
GR79368B (ro)	1984-10-22
AT382367B (de)	1987-02-25
PL243308A1 (en)	1985-12-17
AR241158A1 (es)	1991-12-30
YU43324B (en)	1989-06-30
DD213919A5 (de)	1984-09-26
RO86511B (ro)	1985-03-31
CS243499B2 (en)	1986-06-12
IE55839B1 (en)	1991-01-30
CS26885A2 (en)	1985-08-31
BE897466A (fr)	1984-02-06
PL257440A1 (en)	1986-10-07
CS243474B2 (en)	1986-06-12
US4939253A (en)	1990-07-03
CS243498B2 (en)	1986-06-12
PT77155B (en)	1986-01-28
IE831830L (en)	1984-02-04
ES8502114A1 (es)	1984-12-16
NO832801L (no)	1984-02-06
ATA281283A (de)	1986-07-15
YU162783A (en)	1986-02-28
GB2125794B (en)	1985-12-18
CS575983A2 (en)	1985-08-15
SE8304256D0 (sv)	1983-08-03
IT1224129B (it)	1990-09-26
IL69381A0 (en)	1983-11-30
AU1755683A (en)	1984-02-09
AR241158A2 (es)	1991-12-30
GB2125794A (en)	1984-03-14
DK354683D0 (da)	1983-08-03
FI832675A0 (fi)	1983-07-22
ES524698A0 (es)	1984-12-16
FR2531427A1 (fr)	1984-02-10
NL8302746A (nl)	1984-03-01
SE8304256L (sv)	1984-02-05
KR840005814A (ko)	1984-11-19
IT8322430A0 (it)	1983-08-04
DE3328047A1 (de)	1984-02-09
DK354683A (da)	1984-02-05
PT77155A (en)	1983-09-01
FR2531427B1 (ro)	1985-04-19
CS26783A2 (en)	1985-08-31
SU1329617A3 (ru)	1987-08-07
IN160955B (ro)	1987-08-22
KR900001211B1 (ko)	1990-02-28
GB8320497D0 (en)	1983-09-01
NZ205111A (en)	1986-06-11
CH655309A5 (fr)	1986-04-15
ZA835470B (en)	1984-04-25
HU191058B (en)	1986-12-28

Publication	Publication Date	Title
RO90457A (ro)	1986-12-10	Procedeu pentru prepararea unor n-heterociclil 4-piperidinamine
RO86698A (ro)	1985-04-17	Procedeu pentru prepararea unor (1-piperidinilalchil)-pirimidinone
RO87533A (ro)	1985-10-31	Procedeu pentru prepararea unor n-(biciclicheterociclil)-4-piperidinamine
RO82367A (ro)	1984-02-21	Procedeu pentru prepararea unor compusi antihipercolesterolemici
RO88641A (ro)	1986-02-28	Procedeu pentru prepararea etilenglicolului
RO89436A2 (ro)	1986-06-30	Procedeu pentru prepararea unor(laril-ciclobutil)-alchilamine
RO82162A (ro)	1983-07-07	Procedeu pentru prepararea unor aminotiadiazoli
RO90414A (ro)	1986-12-10	Procedeu pentru prepararea unor n-heterociclil-4-piperidinamine
RO86363A (ro)	1985-03-15	Procedeu pentru prepararea unor derivati de metiltiopirimidina
RO86511A (ro)	1985-03-15	Procedeu pentru prepararea unor beta-lactame
RO86851A (ro)	1985-05-20	Procedeu pentru prepararea unor derivati de piperazin-2-ona
RO89235A (ro)	1986-03-15	Procedeu pentru prepararea unor derivati de tidozina
PT76595A (fr)	1983-05-01	Procede de preparation de benzoazacycloalkyl-spiro-imidazolidines
RO83301A (ro)	1984-02-21	Procedeu pentru prepararea unor peptide
RO86646A (ro)	1985-04-17	Procedeu pentru prepararea unor o0imeteri
RO85558A (ro)	1984-11-25	Procedeu pentru prepararea unor n-halometil-acilamide
RO92200A (ro)	1987-11-30	Procedeu pentru prepararea unor s-benzilcarbamati
FR2503158B1 (fr)	1985-07-26	Procede pour la preparation de dithiazolyldisulfures
RO88202A (ro)	1985-12-30	Procedeu pentru preparare unor spiro-3-heteroazelone
RO82087A (ro)	1983-07-07	Procedeu pentru prepararea 3-picolinei
FR2525219B1 (fr)	1986-04-04	Procede pour la preparation de 4-hydroxy-2-methyl-2h-1,2-benzothiazine-3-carboxamide-1-1-dioxydes
RO83438A (ro)	1984-02-21	Procedeu pentru prepararea unor bis-tetrazolmetiltioli
FR2534905B1 (fr)	1986-03-21	Procede de preparation de phenylcetones
FR2528825B1 (fr)	1986-02-21	Procede de preparation de meta-chlorobenzotrifluorure
FR2527631B1 (fr)	1986-08-22	Procede pour la preparation de steroides