RO85318A - Procedeu pentru prepararea unor derivati de 4-chinolona cu activitateantihipertensiva - Google Patents
Procedeu pentru prepararea unor derivati de 4-chinolona cu activitateantihipertensivaInfo
- Publication number
- RO85318A RO85318A RO81110630A RO11063081A RO85318A RO 85318 A RO85318 A RO 85318A RO 81110630 A RO81110630 A RO 81110630A RO 11063081 A RO11063081 A RO 11063081A RO 85318 A RO85318 A RO 85318A
- Authority
- RO
- Romania
- Prior art keywords
- antihipertensive
- preparation
- action
- quinolone derivatives
- quinolone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8031106 | 1980-09-26 | ||
| GB8031162 | 1980-09-26 | ||
| GB8119062 | 1981-06-19 | ||
| GB8118879 | 1981-06-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO85318A true RO85318A (ro) | 1984-09-29 |
| RO85318B RO85318B (ro) | 1984-10-30 |
Family
ID=27449208
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO81105404A RO82014A (ro) | 1980-09-26 | 1981-09-25 | Procedeu pentru prepararea unor derivati de 4-chinolina cu activitateantihipertensiva |
| RO110630A RO85318B (ro) | 1980-09-26 | 1981-09-25 | Procedeu pentru prepararea unor derivati de 4-chinolona cu activitate antihipertensiva |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO81105404A RO82014A (ro) | 1980-09-26 | 1981-09-25 | Procedeu pentru prepararea unor derivati de 4-chinolina cu activitateantihipertensiva |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US4447435A (ro) |
| AT (1) | AT379388B (ro) |
| AU (1) | AU549078B2 (ro) |
| BG (2) | BG36495A3 (ro) |
| CA (1) | CA1146943A (ro) |
| CH (1) | CH650254A5 (ro) |
| DD (1) | DD201890A5 (ro) |
| DE (1) | DE3138121A1 (ro) |
| DK (1) | DK152674C (ro) |
| ES (2) | ES505786A0 (ro) |
| FI (1) | FI812997L (ro) |
| FR (1) | FR2491064A1 (ro) |
| GR (1) | GR75797B (ro) |
| IE (1) | IE51542B1 (ro) |
| IL (1) | IL63845A (ro) |
| IT (1) | IT1189449B (ro) |
| LU (1) | LU83649A1 (ro) |
| NL (1) | NL8104394A (ro) |
| NO (1) | NO154052C (ro) |
| NZ (1) | NZ198414A (ro) |
| PH (1) | PH18605A (ro) |
| PT (1) | PT73666B (ro) |
| RO (2) | RO82014A (ro) |
| SE (1) | SE457533B (ro) |
| YU (2) | YU230181A (ro) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT79031B (en) * | 1983-08-20 | 1986-08-22 | Boots Co Plc | Therapeutic agents |
| DE3578374D1 (de) * | 1984-01-13 | 1990-08-02 | Boots Co Ltd | Verwendung von chinolonen fuer die herstellung eines arzneimittels zur behandlung von herzerkrankungen. |
| EP0172004B1 (en) * | 1984-08-15 | 1990-03-21 | The Boots Company PLC | Quinolinones, process for their preparation and pharmaceutical compositions containing them |
| GB8515209D0 (en) * | 1985-06-15 | 1985-07-17 | Boots Co Plc | Therapeutic agents |
| GB8515207D0 (en) * | 1985-06-15 | 1985-07-17 | Boots Co Plc | Therapeutic agents |
| GB8627698D0 (en) * | 1986-11-20 | 1986-12-17 | Boots Co Plc | Therapeutic agents |
| GB8726950D0 (en) * | 1987-11-18 | 1987-12-23 | Boots Co Plc | Chemical process |
| GB8804016D0 (en) * | 1988-02-22 | 1988-03-23 | Boots Co Plc | Therapeutic agents |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3121725A (en) * | 1960-07-18 | 1964-02-18 | Phillips Petroleum Co | N-heterocyclic sulfides, sulfoxides, sulfones, and n-oxides of said sulfoxides and sulfones |
| US3801644A (en) * | 1971-08-25 | 1974-04-02 | Warner Lambert Co | Substituted-o-hydroxy-omega-(methylsulfinyl)acetophenones and process for producing same |
| US3772301A (en) * | 1971-11-22 | 1973-11-13 | Warner Lambert Co | (4-substituted)4-(methylsulfinyl)methylcarbostyrils |
| US4343805A (en) * | 1978-12-16 | 1982-08-10 | John Wyeth & Brother Limited | Heterocyclic compounds |
| GB2038825B (en) * | 1978-12-16 | 1983-02-09 | Wyeth John & Brother Ltd | Heterocyclic compounds substituted by heterocyclyl-alkyl-thio groups |
| NZ193167A (en) * | 1979-03-27 | 1984-08-24 | Boots Co Plc | Quinoline derivatives and pharmaceutical compositions |
| ZA801575B (en) * | 1979-03-27 | 1981-03-25 | Boots Co Ltd | Therapeutic agents |
| US4302360A (en) * | 1980-01-11 | 1981-11-24 | Agency Of Industrial Science & Technology | Catalyst for catalytic combustion of hydrogen |
-
1981
- 1981-09-02 IE IE2033/81A patent/IE51542B1/en unknown
- 1981-09-14 PT PT73666A patent/PT73666B/pt unknown
- 1981-09-14 PH PH26202A patent/PH18605A/en unknown
- 1981-09-16 IL IL63845A patent/IL63845A/xx unknown
- 1981-09-18 GR GR66095A patent/GR75797B/el unknown
- 1981-09-18 FR FR8117630A patent/FR2491064A1/fr active Granted
- 1981-09-21 NZ NZ198414A patent/NZ198414A/xx unknown
- 1981-09-21 US US06/304,165 patent/US4447435A/en not_active Expired - Fee Related
- 1981-09-21 AU AU75524/81A patent/AU549078B2/en not_active Ceased
- 1981-09-21 US US06/303,948 patent/US4442109A/en not_active Expired - Fee Related
- 1981-09-23 BG BG062845A patent/BG36495A3/xx unknown
- 1981-09-23 BG BG053612A patent/BG36344A3/xx unknown
- 1981-09-23 CA CA000386485A patent/CA1146943A/en not_active Expired
- 1981-09-24 NL NL8104394A patent/NL8104394A/nl not_active Application Discontinuation
- 1981-09-24 DE DE19813138121 patent/DE3138121A1/de not_active Ceased
- 1981-09-24 LU LU83649A patent/LU83649A1/fr unknown
- 1981-09-24 YU YU02301/81A patent/YU230181A/xx unknown
- 1981-09-25 NO NO813263A patent/NO154052C/no unknown
- 1981-09-25 AT AT0412181A patent/AT379388B/de not_active IP Right Cessation
- 1981-09-25 RO RO81105404A patent/RO82014A/ro unknown
- 1981-09-25 CH CH6235/81A patent/CH650254A5/fr not_active IP Right Cessation
- 1981-09-25 IT IT49370/81A patent/IT1189449B/it active
- 1981-09-25 DK DK424781A patent/DK152674C/da active
- 1981-09-25 SE SE8105689A patent/SE457533B/sv not_active IP Right Cessation
- 1981-09-25 FI FI812997A patent/FI812997L/fi not_active Application Discontinuation
- 1981-09-25 RO RO110630A patent/RO85318B/ro unknown
- 1981-09-25 ES ES505786A patent/ES505786A0/es active Granted
- 1981-09-28 DD DD81233630A patent/DD201890A5/de unknown
-
1982
- 1982-07-27 ES ES514411A patent/ES8306111A1/es not_active Expired
-
1983
- 1983-07-01 YU YU01446/83A patent/YU144683A/xx unknown
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