RO62762A - Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues - Google Patents

Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues

Info

Publication number: RO62762A
Authority: RO; Romania
Prior art keywords: pyrimidines; tri; substituted; preparation
Prior art date: 1971-12-09

Application number

RO7200073093A

Other languages

English (en)

Romanian (ro)

Inventor

Roland K Robins

Darrel E O'brien

Thomas Novinson

Robert H Springer

Original Assignee

Icn Pharmaceutical Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-12-09

Filing date

1972-12-09

Publication date

1978-05-15

1972-04-20 Priority claimed from US245870A external-priority patent/US3925385A/en

1972-12-09 Application filed by Icn Pharmaceutical Inc filed Critical Icn Pharmaceutical Inc

1978-05-15 Publication of RO62762A publication Critical patent/RO62762A/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

RO7200073093A 1971-12-09 1972-12-09 Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues RO62762A (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US20653871A	1971-12-09	1971-12-09
US245870A US3925385A (en)	1972-04-20	1972-04-20	6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines
US27346572A	1972-07-20	1972-07-20
US29984072A	1972-10-24	1972-10-24

Publications (1)

Publication Number	Publication Date
RO62762A true RO62762A (fr)	1978-05-15

Family

ID=27498614

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
RO7200073093A RO62762A (fr)	1971-12-09	1972-12-09	Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues

Country Status (15)

Country	Link
JP (1)	JPS4864097A (fr)
BE (1)	BE792533A (fr)
BG (1)	BG22401A3 (fr)
CH (1)	CH603652A5 (fr)
DD (1)	DD104530A5 (fr)
DE (1)	DE2257547A1 (fr)
GB (1)	GB1412017A (fr)
HU (1)	HU168530B (fr)
IE (1)	IE37189B1 (fr)
IL (1)	IL40895A (fr)
LU (1)	LU66597A1 (fr)
NL (1)	NL7216539A (fr)
NO (1)	NO137012C (fr)
RO (1)	RO62762A (fr)
SE (1)	SE398751B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4281000A (en) *	1979-07-09	1981-07-28	American Cyanamid Company	Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
AU557300B2 (en) *	1982-03-16	1986-12-18	Farmitalia Carlo Erba S.P.A.	Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation
ZA831407B (en) *	1982-03-25	1983-11-30	Erba Farmitalia	Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation
NZ208554A (en) *	1983-06-23	1987-06-30	American Cyanamid Co	(aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions
DE3533050A1 (de) *	1985-09-17	1987-03-26	Basf Ag	7-amino-azolo(1,5-a)pyrimidine, verfahren zu ihrer herstellung und diese enthaltende fungizide, bzw. deren verwendung als fungizide
CA1330079C (fr) *	1988-10-13	1994-06-07	Michihiko Tsujitani	Derive pyrrolo-(3,2-e)pyrazolo(1,5-a)pyrimidine et medicament en contenant
CA2107479C (fr) *	1991-04-22	1997-12-16	Makoto Inoue	Derives de pyrazolo[1,5-a]pyrimidine et agent antiinflammatoire les renfermant
DE4333705C2 (de) *	1993-10-02	2003-10-30	Guenter Ege	Arylmethylsubstituierte Pyrazolo-azine, insbesondere 3-Arylmethylpyrazolo[1,5-a]pyrimidine und Verfahren zur Herstellung von 8-Arylmethyl-pyrazolo[5,1-c][1,2,4]triazinen
DE69523864T2 (de) *	1994-06-21	2002-06-13	Otsuka Pharmaceutical Factory, Inc.	PYRAZOLO[1,5-a] PYRIMIDIN-DERIVATE
KR100260292B1 (ko) *	1995-09-28	2000-07-01	오쓰카 요시미쓰	진통제
FR2771631B1 (fr) *	1997-12-03	2001-02-02	Oreal	Compositions de teinture des fibres keratiniques contenant des 3-amino pyrazolo-[1,5-a]-pyrimidines, procede de teinture, nouvelles 3-amino pyrazolo- [1,5-a]-pyrimidines et leur procede de preparation
CA2497440C (fr) *	2002-09-04	2011-03-22	Schering Corporation	Pyrazolopyrimidines tenant lieu d'inhibiteurs de kinases dependantes de la cycline
US7119200B2 (en) *	2002-09-04	2006-10-10	Schering Corporation	Pyrazolopyrimidines as cyclin dependent kinase inhibitors
US7161003B1 (en) *	2002-09-04	2007-01-09	Schering Corporation	Pyrazolopyrimidines as cyclin dependent kinase inhibitors
TWI252851B (en) *	2003-07-24	2006-04-11	Ferrer Int	7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto
ES2222813B1 (es) *	2003-07-24	2005-12-16	Ferrer Internacional, S.A.	N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
RS55770B1 (sr)	2013-04-25	2017-07-31	Beigene Ltd	Fuzionisana heterociklična jedinjenja kao inhibitori protein kinaze
SMT202300039T1 (it)	2013-09-13	2023-03-17	Beigene Switzerland Gmbh	Anticorpi anti-pd1 e loro uso come terapia e per diagnostica
WO2016000619A1 (fr)	2014-07-03	2016-01-07	Beigene, Ltd.	Anticorps anti-pd-l1 et leur utilisation comme agents thérapeutiques et diagnostiques
JP6993056B2 (ja)	2016-07-05	2022-02-15	ベイジーンリミテッド	癌治療のためのｐｄ－１アンタゴニスト及びｒａｆ阻害剤の組合せ
IL293319A (en)	2016-08-16	2022-07-01	Beigene Ltd	Crystalline form of (s)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo(1,5-a)pyrimidine-3- carboxamide, preparation, and uses thereof
PT3500299T (pt)	2016-08-19	2024-02-21	Beigene Switzerland Gmbh	Combinação de zanubrutinib com um anticorpo anti-cd20 ou anti-pd-1 para utilização no tratamento do cancro
WO2018137681A1 (fr)	2017-01-25	2018-08-02	Beigene, Ltd.	Formes cristallines de (s) -7- (1- (but-2-ynoyl) pipéridin-4-yl) -2- (4-phénoxyphényl) -4, 5, 6, 7-tétrahy dropyrazolo [1, 5-a] pyrimidine-3-carboxamide, préparation et utilisations associées
WO2019001417A1 (fr)	2017-06-26	2019-01-03	Beigene, Ltd.	Immunothérapie pour carcinome hépatocellulaire
WO2019034009A1 (fr)	2017-08-12	2019-02-21	Beigene, Ltd.	Inhibiteur de btk ayant une double sélectivité améliorée
CN111801334B (zh)	2017-11-29	2023-06-09	百济神州瑞士有限责任公司	使用包含btk抑制剂的组合治疗惰性或侵袭性b-细胞淋巴瘤
US11786531B1 (en)	2022-06-08	2023-10-17	Beigene Switzerland Gmbh	Methods of treating B-cell proliferative disorder

0
- BE BE792533D patent/BE792533A/fr unknown
1972
- 1972-11-21 IE IE1612/72A patent/IE37189B1/xx unknown
- 1972-11-22 IL IL40895A patent/IL40895A/en unknown
- 1972-11-23 DE DE2257547A patent/DE2257547A1/de active Pending
- 1972-12-01 GB GB5558772A patent/GB1412017A/en not_active Expired
- 1972-12-05 LU LU66597A patent/LU66597A1/xx unknown
- 1972-12-05 SE SE7215829A patent/SE398751B/xx unknown
- 1972-12-06 CH CH1775172A patent/CH603652A5/xx not_active IP Right Cessation
- 1972-12-06 NO NO4476/72A patent/NO137012C/no unknown
- 1972-12-06 NL NL7216539A patent/NL7216539A/xx not_active Application Discontinuation
- 1972-12-07 DD DD167370A patent/DD104530A5/xx unknown
- 1972-12-08 HU HUIE548A patent/HU168530B/hu unknown
- 1972-12-09 BG BG022071A patent/BG22401A3/xx unknown
- 1972-12-09 RO RO7200073093A patent/RO62762A/fr unknown
- 1972-12-09 JP JP47123877A patent/JPS4864097A/ja active Pending

Also Published As

Publication number	Publication date
GB1412017A (en)	1975-10-29
IE37189L (en)	1973-06-09
NO137012C (no)	1977-12-14
DD104530A5 (fr)	1974-03-12
CH603652A5 (fr)	1978-08-31
BE792533A (fr)	1973-06-08
IL40895A (en)	1976-12-31
IE37189B1 (en)	1977-05-25
JPS4864097A (fr)	1973-09-05
LU66597A1 (fr)	1973-03-15
NL7216539A (fr)	1973-06-13
DE2257547A1 (de)	1973-06-14
HU168530B (fr)	1976-05-28
BG22401A3 (bg)	1977-02-20
NO137012B (no)	1977-09-05
IL40895A0 (en)	1973-01-30
SE398751B (sv)	1978-01-16

Publication	Publication Date	Title
RO62435A (fr)	1978-03-15	Procede pour la preparation des 1,2,4-triazolenucleosides
RO62762A (fr)	1978-05-15	Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues
BE792326A (fr)	1973-03-30	Procede pour la preparation d'halogenohydrines
RO67478A (fr)	1980-03-15	Procede pour la preparation des pleuromutillines
RO62428A (fr)	1978-01-15	Procede pour la preparation des thyeno-(3,2-d)-pyrimidines
RO62861A (fr)	1977-11-15	Procede pour la preparation des di-n-oxydes-(1,4)-benzo-1,2,4-triazines
RO70438A (fr)	1981-04-30	Procede pour la preparation des pyrrol-2-carboxamides substitus
RO62694A (fr)	1978-05-15	Procede pour la preparation des 3-methylencephalosporines
RO63551A (fr)	1978-07-15	Procede pour la preparation des thieno-(3,2-d)-pyrimidines
RO64269A (fr)	1979-05-15	Procede pour la preparation des izoxazole-(5,4-d)-pirymidines
RO62699A (fr)	1978-03-15	Procede pour la preparation des 3-benzylpyridines subst
BE807434A (fr)	1974-05-16	Procede pour la preparation de 3,6-dihalo-diphenyl-alcanes
RO63031A (fr)	1978-05-15	Procede pour la preparation des pyrido-(3,2-d)-pyrimidi
CH549579A (fr)	1974-05-31	Procede pour la preparation de nouvelles hydroxy-pyrimidines.
CH550187A (fr)	1974-06-14	Procede de preparation de l'eburnamonine.
CH553178A (fr)	1974-08-30	Procede pour la preparation de la 3-hydroxy-2-alcoyl4-pyrone.
BE790056A (fr)	1973-04-13	Procede de preparation de 1, 1'-dianthraquinonyles
RO62512A (fr)	1978-02-15	Procede pour la preparation des thiazolo-(5,4-d)-pyrimidines
RO62312A (fr)	1977-12-15	Procede pour la preparation des 6-aza-3h-1,4-benzodiazepines
RO62467A (fr)	1977-11-15	Procede pour la preparation des 1-hydrocarbyl-3,4,5-tribrompyrazoles substitues
BE790055A (fr)	1973-04-13	Procede de preparation de 1,1'-dianthraquinonyles
RO64143A (fr)	1978-10-15	Procede pour la preparation des 5-alkyle-5 aralcolxy-1,3-dioxanes
RO62390A (fr)	1978-02-15	Procede pour la preparation des composes acylpropandiole-(1,3-)-phosphates de quoline
BE796204A (fr)	1973-09-03	Procede pour la preparation de 3,4,5,6,7,8-hexahydrocoumarine
BE761876A (fr)	1971-07-01	Procede pour la preparation de 1, 1' - peroxydicyclohexylamine