PT998477E - PHENOIS AND THIOFENOIS ALQUIL-4-SILYLIC-HETEROCYCLICS AS ANTIOXIDANT AGENTS - Google Patents

PHENOIS AND THIOFENOIS ALQUIL-4-SILYLIC-HETEROCYCLICS AS ANTIOXIDANT AGENTS

Info

Publication number: PT998477E
Authority: PT; Portugal
Prior art keywords: thiofenois; silylic; phenois; alquil; heterocyclics
Prior art date: 1997-06-24

Application number

PT98923681T

Other languages

Portuguese (pt)

Inventor

Michael L Edwards

Steven J Busch

Paul S Wright

James E Matt Jr

Roger A Parker

Mark J Vaal

Kim S Chen

Mark T Yates

Original Assignee

Aventis Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-24

Filing date

1998-05-21

Publication date

2003-07-31

1998-05-21 Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc

2003-07-31 Publication of PT998477E publication Critical patent/PT998477E/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Immunology (AREA)
Obesity (AREA)
Hematology (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PT98923681T 1997-06-24 1998-05-21 PHENOIS AND THIOFENOIS ALQUIL-4-SILYLIC-HETEROCYCLICS AS ANTIOXIDANT AGENTS PT998477E (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US88162797A	1997-06-24	1997-06-24
PCT/US1998/010510 WO1998058938A1 (en)	1997-06-24	1998-05-21	Alkyl-4-silylheterocyclic phenols and thiophenols as antioxidant agents

Publications (1)

Publication Number	Publication Date
PT998477E true PT998477E (en)	2003-07-31

Family

ID=25378856

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98923681T PT998477E (en)	1997-06-24	1998-05-21	PHENOIS AND THIOFENOIS ALQUIL-4-SILYLIC-HETEROCYCLICS AS ANTIOXIDANT AGENTS

Country Status (22)

Country	Link
EP (1)	EP0998477B1 (en)
JP (1)	JP2002514226A (en)
KR (1)	KR20010014118A (en)
CN (1)	CN1147495C (en)
AR (1)	AR013114A1 (en)
AT (1)	ATE235498T1 (en)
AU (1)	AU731278B2 (en)
BR (1)	BR9810311A (en)
CA (1)	CA2293461C (en)
DE (1)	DE69812635T2 (en)
DK (1)	DK0998477T3 (en)
ES (1)	ES2190592T3 (en)
HK (1)	HK1027815A1 (en)
HU (1)	HUP0002775A3 (en)
IL (1)	IL133598A (en)
NO (1)	NO996395L (en)
NZ (1)	NZ501342A (en)
PT (1)	PT998477E (en)
SI (1)	SI0998477T1 (en)
TW (1)	TW517054B (en)
WO (1)	WO1998058938A1 (en)
ZA (1)	ZA985318B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005039596A1 (en) *	2003-10-17	2005-05-06	Amylin Pharmaceuticals, Inc.	Silyl phenols for promoting vascular health

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5155250A (en) *	1990-07-05	1992-10-13	Merrell Dow Pharmaceuticals Inc.	2,6-di-alkyl-4-silyl-phenols as antiatheroscerotic agents
EP1468692B1 (en) *	1993-12-10	2006-04-26	Merrell Pharmaceuticals Inc.	Use of 2,6-di-alkyl-4-silyl-phenols for treating xanthoma

1998
- 1998-05-21 BR BR9810311-3A patent/BR9810311A/en not_active IP Right Cessation
- 1998-05-21 IL IL13359898A patent/IL133598A/en not_active IP Right Cessation
- 1998-05-21 DK DK98923681T patent/DK0998477T3/en active
- 1998-05-21 AU AU75915/98A patent/AU731278B2/en not_active Ceased
- 1998-05-21 DE DE69812635T patent/DE69812635T2/en not_active Expired - Fee Related
- 1998-05-21 NZ NZ501342A patent/NZ501342A/en unknown
- 1998-05-21 AT AT98923681T patent/ATE235498T1/en not_active IP Right Cessation
- 1998-05-21 CN CNB988065770A patent/CN1147495C/en not_active Expired - Fee Related
- 1998-05-21 WO PCT/US1998/010510 patent/WO1998058938A1/en active IP Right Grant
- 1998-05-21 HU HU0002775A patent/HUP0002775A3/en unknown
- 1998-05-21 CA CA002293461A patent/CA2293461C/en not_active Expired - Fee Related
- 1998-05-21 ES ES98923681T patent/ES2190592T3/en not_active Expired - Lifetime
- 1998-05-21 JP JP50443199A patent/JP2002514226A/en active Pending
- 1998-05-21 KR KR19997012174A patent/KR20010014118A/en active IP Right Grant
- 1998-05-21 SI SI9830429T patent/SI0998477T1/en unknown
- 1998-05-21 EP EP98923681A patent/EP0998477B1/en not_active Expired - Lifetime
- 1998-05-21 PT PT98923681T patent/PT998477E/en unknown
- 1998-06-18 ZA ZA985318A patent/ZA985318B/en unknown
- 1998-06-19 TW TW087109867A patent/TW517054B/en not_active IP Right Cessation
- 1998-06-22 AR ARP980102977A patent/AR013114A1/en not_active Application Discontinuation
1999
- 1999-12-22 NO NO996395A patent/NO996395L/en not_active Application Discontinuation
2000
- 2000-11-09 HK HK00107137A patent/HK1027815A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69812635T2 (en)	2003-10-23
IL133598A (en)	2004-08-31
HUP0002775A2 (en)	2001-05-28
JP2002514226A (en)	2002-05-14
KR20010014118A (en)	2001-02-26
CA2293461C (en)	2004-02-24
DK0998477T3 (en)	2003-07-21
AU7591598A (en)	1999-01-04
NZ501342A (en)	2001-10-26
HK1027815A1 (en)	2001-01-23
TW517054B (en)	2003-01-11
WO1998058938A1 (en)	1998-12-30
NO996395D0 (en)	1999-12-22
SI0998477T1 (en)	2003-08-31
DE69812635D1 (en)	2003-04-30
ES2190592T3 (en)	2003-08-01
CN1147495C (en)	2004-04-28
IL133598A0 (en)	2001-04-30
BR9810311A (en)	2000-09-19
AR013114A1 (en)	2000-12-13
CA2293461A1 (en)	1998-12-30
AU731278B2 (en)	2001-03-29
CN1261367A (en)	2000-07-26
HUP0002775A3 (en)	2001-08-28
EP0998477B1 (en)	2003-03-26
NO996395L (en)	2000-02-23
ZA985318B (en)	1999-01-11
ATE235498T1 (en)	2003-04-15
EP0998477A1 (en)	2000-05-10

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PT1084114E (en)	2004-12-31	ISOTIAZOLE UTEIS DERIVATIVES AS ANTICANCERIGENE AGENTS
NO20005488D0 (en)	2000-10-31	Hematopoietic stimulation
PT1015434E (en)	2002-08-30	NEW PYRIMIDIN-4-ONA AND PYRIMIDIN-4-TIONA AS FUNGICIDES
DE59802860D1 (en)	2002-02-28	DISINFECTANT
ID30031A (en)	2001-11-01	AGROKIMIA FORMULATIONS
ID23546A (en)	2000-05-04	ZIPRASIDON FORMULATIONS
PT1235811E (en)	2005-10-31	PYRAZOLECARBOXAMIDE AND PYRAZOLETIOAMIDE AS FUNGICIDES
PT802184E (en)	2002-09-30	N-BENZYL-2-PHENYLINDOLS AS ESTROGENIC AGENTS
NO20004240L (en)	2000-10-18	formulations
ATE224703T1 (en)	2002-10-15	EFFORTABLE FORMULATIONS
NO20000125D0 (en)	2000-01-10	Tiadiazolyl and oxadiazolylphenyloxazolidinone antibacterial agents
PT1105375E (en)	2006-07-31	TRIFLUOROMETHYLPYROLECARBOXAMIDES AS FUNGICIDES
PT1130966E (en)	2005-04-29	ANTIPARASITARY FORMULATIONS
DE59807782D1 (en)	2003-05-15	Puncture
DE69902762D1 (en)	2002-10-10	RISER-SPAN ARRANGEMENT
DE59912684D1 (en)	2006-03-02	FILM-DRIVEN AGENTS
PT942896E (en)	2003-07-31	UTILIZED SUBSTITUTED PHENOIS AND THIOFENOES AS ANTIOXIDANT AGENTS
FR2774599B1 (en)	2001-10-05	POULTICE
PT1075471E (en)	2005-02-28	INDOLIL DERIVATIVES AS SERONERGIC AGENTS
ID22406A (en)	1999-10-14	POISON COMPOSITION
NO306533B1 (en)	1999-11-22	insecticide
ATA25298A (en)	2000-05-15	HOOF PROTECTION
FI19992526A (en)	2000-01-25	Seen Composition
PT998477E (en)	2003-07-31	PHENOIS AND THIOFENOIS ALQUIL-4-SILYLIC-HETEROCYCLICS AS ANTIOXIDANT AGENTS