PT98538A - Processo de preparacao de factor de crescimento humano epidermico (hegf) dos seus congeneres e de composicoes farmaceuticas que os contem - Google Patents

Processo de preparacao de factor de crescimento humano epidermico (hegf) dos seus congeneres e de composicoes farmaceuticas que os contem

Info

Publication number: PT98538A
Authority: PT; Portugal
Prior art keywords: growth factor; pure; hegf; species; congenerers
Prior art date: 1990-08-02

Application number

PT98538A

Other languages

English (en)

Other versions

PT98538B (pt

Inventor

Indu Parikh

Ronald Nardi

Tanchum Amarant

Antonio Guglietta

Original Assignee

Indu Parikh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-02

Filing date

1991-08-01

Publication date

1992-06-30

1991-08-01 Application filed by Indu Parikh filed Critical Indu Parikh

1992-06-30 Publication of PT98538A publication Critical patent/PT98538A/pt

1999-01-29 Publication of PT98538B publication Critical patent/PT98538B/pt

Links

239000003102 growth factor Substances 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
102000009024 Epidermal Growth Factor Human genes 0.000 abstract 1
101800003838 Epidermal growth factor Proteins 0.000 abstract 1
230000002159 abnormal effect Effects 0.000 abstract 1
230000010261 cell growth Effects 0.000 abstract 1
239000000039 congener Substances 0.000 abstract 1
239000002552 dosage form Substances 0.000 abstract 1
230000002183 duodenal effect Effects 0.000 abstract 1
230000007515 enzymatic degradation Effects 0.000 abstract 1
229940116977 epidermal growth factor Drugs 0.000 abstract 1
230000002496 gastric effect Effects 0.000 abstract 1
230000003902 lesion Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)

PT98538A 1990-08-02 1991-08-01 Processo de preparacao de factor de crescimento humano epidermico (hegf) dos seus congeneres e de composicoes farmaceuticas que os contem PT98538B (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US56152590A	1990-08-02	1990-08-02
US59133990A	1990-10-01	1990-10-01

Publications (2)

Publication Number	Publication Date
PT98538A true PT98538A (pt)	1992-06-30
PT98538B PT98538B (pt)	1999-01-29

Family

ID=27072670

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98538A PT98538B (pt)	1990-08-02	1991-08-01	Processo de preparacao de factor de crescimento humano epidermico (hegf) dos seus congeneres e de composicoes farmaceuticas que os contem

Country Status (11)

Country	Link
EP (1)	EP0541726B1 (pt)
JP (1)	JP3195793B2 (pt)
AT (1)	ATE190628T1 (pt)
AU (1)	AU660421B2 (pt)
DE (1)	DE69132050T2 (pt)
DK (1)	DK0541726T3 (pt)
ES (1)	ES2145740T3 (pt)
GR (1)	GR3033649T3 (pt)
IE (1)	IE912738A1 (pt)
PT (1)	PT98538B (pt)
WO (1)	WO1992002246A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5434135A (en) *	1990-08-02	1995-07-18	Indu Parikh	Growth factor compositions, preparation and use
US6558952B1 (en) *	1992-12-14	2003-05-06	Waratah Pharmaceuticals, Inc.	Treatment for diabetes
US5814308A (en) *	1996-03-26	1998-09-29	Zhang; Ke	Methods for the treatment of gastrointestinal tract disorders
US6579308B1 (en)	2000-11-28	2003-06-17	Scimed Life Systems, Inc.	Stent devices with detachable distal or proximal wires
CN116036241A (zh) *	2023-02-17	2023-05-02	固德生技有限公司	表皮生长因子在制备用于治疗胃溃疡的药物上的应用
WO2024168796A1 (zh) *	2023-02-17	2024-08-22	固德生技有限公司	表皮生长因子在制备用于治疗胃溃疡的药物上的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3813834A (en) *	1970-05-28	1974-06-04	Prod Eng Inc	Joist with nailing strip and positioning members
IE38892B1 (en) *	1973-03-28	1978-06-21	Ici Ltd	Pharmaceutical compositions
GB1461105A (en) *	1974-09-11	1977-01-13	Ici Ltd	Gastric acid-inhibiting polypeptide
IE53166B1 (en) *	1980-08-05	1988-08-03	Searle & Co	Synthetic urogastrone gene,corresponding plasmid recombinants,transformed cells,production thereof and urogastrone expression
GB8409960D0 (en) *	1984-04-17	1984-05-31	Searle & Co	Therapeutic method
GB8509448D0 (en) *	1985-04-12	1985-05-15	Ici Plc	Urogastrone
JPS6377823A (ja) *	1986-09-19	1988-04-08	Fujisawa Pharmaceut Co Ltd	抗癌剤
JPH04501662A (ja) *	1988-09-26	1992-03-26	ザ・サルク・インスティチュート・バイオテクノロジー／インダストリアル・アソシエイツ・インコーポレーテッド	混合給送組換え酵母発酵

1991
- 1991-07-30 AT AT91917666T patent/ATE190628T1/de not_active IP Right Cessation
- 1991-07-30 EP EP91917666A patent/EP0541726B1/en not_active Expired - Lifetime
- 1991-07-30 DK DK91917666T patent/DK0541726T3/da active
- 1991-07-30 AU AU86445/91A patent/AU660421B2/en not_active Ceased
- 1991-07-30 DE DE69132050T patent/DE69132050T2/de not_active Expired - Fee Related
- 1991-07-30 WO PCT/US1991/005396 patent/WO1992002246A1/en active IP Right Grant
- 1991-07-30 JP JP51602791A patent/JP3195793B2/ja not_active Expired - Fee Related
- 1991-07-30 ES ES91917666T patent/ES2145740T3/es not_active Expired - Lifetime
- 1991-08-01 PT PT98538A patent/PT98538B/pt not_active IP Right Cessation
- 1991-08-01 IE IE273891A patent/IE912738A1/en not_active IP Right Cessation
2000
- 2000-06-13 GR GR20000401336T patent/GR3033649T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0541726T3 (da)	2000-08-21
EP0541726A4 (en)	1993-12-29
WO1992002246A1 (en)	1992-02-20
ES2145740T3 (es)	2000-07-16
JPH06502626A (ja)	1994-03-24
GR3033649T3 (en)	2000-10-31
EP0541726B1 (en)	2000-03-15
AU8644591A (en)	1992-03-02
DE69132050D1 (de)	2000-04-20
EP0541726A1 (en)	1993-05-19
ATE190628T1 (de)	2000-04-15
PT98538B (pt)	1999-01-29
DE69132050T2 (de)	2001-01-11
JP3195793B2 (ja)	2001-08-06
AU660421B2 (en)	1995-06-29
IE912738A1 (en)	1992-02-12

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Legal Events

Date	Code	Title	Description
1992-06-30	BB1A	Laying open of patent application	Effective date: 19920207
1999-01-29	FG3A	Patent granted, date of granting	Effective date: 19981013
2009-04-21	MM4A	Annulment/lapse due to non-payment of fees, searched and examined patent	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20090413

Date

Code

Title

Description

1992-06-30

BB1A

Laying open of patent application

Effective date: 19920207

1999-01-29

FG3A

Patent granted, date of granting

Effective date: 19981013

2009-04-21

MM4A

Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20090413