[go: up one dir, main page]

PT981644E - Mutacao apc associada com o cancro colorectal familiar em judeus ashkenazi - Google Patents

Mutacao apc associada com o cancro colorectal familiar em judeus ashkenazi

Info

Publication number
PT981644E
PT981644E PT98903558T PT98903558T PT981644E PT 981644 E PT981644 E PT 981644E PT 98903558 T PT98903558 T PT 98903558T PT 98903558 T PT98903558 T PT 98903558T PT 981644 E PT981644 E PT 981644E
Authority
PT
Portugal
Prior art keywords
colorectal cancer
ashkenazi
family
mutaca
judeus
Prior art date
Application number
PT98903558T
Other languages
English (en)
Inventor
Steve Laken
Stephen Gruber
Gloria Petersen
Kenneth Kinzler
Bert Vogelstein
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of PT981644E publication Critical patent/PT981644E/pt

Links

Classifications

    • G01N33/575—
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G01N33/57535—
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT98903558T 1997-01-31 1998-01-21 Mutacao apc associada com o cancro colorectal familiar em judeus ashkenazi PT981644E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/791,883 US5879890A (en) 1997-01-31 1997-01-31 APC mutation associated with familial colorectal cancer in Ashkenazi jews

Publications (1)

Publication Number Publication Date
PT981644E true PT981644E (pt) 2003-09-30

Family

ID=25155083

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98903558T PT981644E (pt) 1997-01-31 1998-01-21 Mutacao apc associada com o cancro colorectal familiar em judeus ashkenazi

Country Status (11)

Country Link
US (2) US5879890A (pt)
EP (1) EP0981644B1 (pt)
AT (1) ATE240407T1 (pt)
AU (1) AU6030498A (pt)
CA (1) CA2278781A1 (pt)
DE (1) DE69814622T2 (pt)
DK (1) DK0981644T3 (pt)
ES (1) ES2200311T3 (pt)
IL (1) IL131167A (pt)
PT (1) PT981644E (pt)
WO (1) WO1998033940A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6210941B1 (en) 1997-06-27 2001-04-03 The Trustees Of Boston University Methods for the detection and isolation of proteins
US5643722A (en) 1994-05-11 1997-07-01 Trustees Of Boston University Methods for the detection and isolation of proteins
CA2239733C (en) † 1995-12-18 2001-04-03 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
US5879890A (en) * 1997-01-31 1999-03-09 The Johns Hopkins University APC mutation associated with familial colorectal cancer in Ashkenazi jews
DE69914770T2 (de) 1998-08-20 2005-05-12 The Johns Hopkins University School Of Medicine Mitochondriale, als tumormarker geeignete mutationen, die nur ein basenpaar betreffen
DE19848665A1 (de) * 1998-10-22 2000-04-27 Bayer Ag Ein automatisierbarer Schnelltest zum direkten Nachweis der APC Resistenz Mutation mit spezifischen Primern und Probes
AU5460500A (en) 1999-06-04 2000-12-28 Massachusetts Institute Of Technology Compositions and methods for the screening of compounds to enhance or reduce apoptosis
US6306628B1 (en) 1999-08-25 2001-10-23 Ambergen, Incorporated Methods for the detection, analysis and isolation of Nascent proteins
WO2004090547A2 (en) * 2003-04-04 2004-10-21 Protein Design Labs, Inc. Metastatic colorectal cancer signatures
DE10345021A1 (de) * 2003-09-23 2005-05-04 Univ Potsdam Verfahren zur nichtinvasiven Früherkennung von Dickdarmkrebs und/oder Darmkrebsvorläuferzellen
WO2022039565A1 (ko) * 2020-08-20 2022-02-24 (주)지놈오피니언 연령 관련 황반변성 진단용 바이오마커 및 이의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69231734T2 (de) * 1991-01-16 2001-09-20 Japan Found Cancer Geerbte und somatische mutationen des apc-gens bei menschlichem colorectal-krebs
US5352775A (en) * 1991-01-16 1994-10-04 The Johns Hopkins Univ. APC gene and nucleic acid probes derived therefrom
AU6350894A (en) * 1993-03-05 1994-09-26 Clifford W. Schweinfest Colon mucosa gene having down-regulated expression in colon adenomas and adenocarcinomas
EP0689606A1 (en) * 1993-03-19 1996-01-03 The Johns Hopkins University ANTIBODIES AND ASSAYS FOR DETERMINING MUTATIONS IN THE $i(APC) GENE
US5591826A (en) * 1993-05-05 1997-01-07 The Johns Hopkins University Human MSH2 protein
US5709998A (en) * 1993-12-15 1998-01-20 The Johns Hopkins University Molecular diagnosis of familial adenomatous polyposis
US5879890A (en) * 1997-01-31 1999-03-09 The Johns Hopkins University APC mutation associated with familial colorectal cancer in Ashkenazi jews

Also Published As

Publication number Publication date
US6013461A (en) 2000-01-11
DE69814622D1 (de) 2003-06-18
EP0981644B1 (en) 2003-05-14
ATE240407T1 (de) 2003-05-15
IL131167A0 (en) 2001-01-28
IL131167A (en) 2002-02-10
CA2278781A1 (en) 1998-08-06
DE69814622T2 (de) 2004-02-26
ES2200311T3 (es) 2004-03-01
DK0981644T3 (da) 2003-08-25
US5879890A (en) 1999-03-09
EP0981644A1 (en) 2000-03-01
AU6030498A (en) 1998-08-25
WO1998033940A1 (en) 1998-08-06

Similar Documents

Publication Publication Date Title
ATE209660T1 (de) 17q-verbundenes ovarial- und brustkrebs empfindlichkeitsgen
PT981644E (pt) Mutacao apc associada com o cancro colorectal familiar em judeus ashkenazi
DK0705903T3 (da) Mutationer i det 17q-koblede bryst- og ovariecancerprædisponeringen
ATE408422T1 (de) Methode zur hemmung immunstimulatorischer mit dna assoziierter antworten
CY1116265T1 (el) Kit ραδιοεπισημανσης και προσδιορισμος δεσμευσης
DE69938867D1 (de) Verfahren und verwendung von anordungen von proteinfixierungsmitteln
DE69735445D1 (de) Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung
DE69833105D1 (de) Verfahren zur feststellung der anwesenheit mutierten brca proteins
DE69510410D1 (de) Proteinkinase
FI915150A7 (fi) Menetelmät, reagenssit ja testikäyttöpakkaukset biologisten yksiköiden alapopulaatioiden määrittämiseksi
NO862908D0 (no) In situ bestemmelse av totalt karbon og vurdering av steinkilde fra dette.
DE69738687D1 (de) Sonden, kits und assays
DE69932845D1 (de) Methoden zur quantifizierung von hla-dr und cd11b
ATE264922T1 (de) Verfahren zur erkennung von klonalen populationen von transformierten zellen in einer genomisch heterogenen zellulären probe
FI910822A7 (fi) Menetelmä DNA-polymeraasin määrittämiseksi kvantitatiivisesti ja siinäkäyttökelpoinen koepakkaus
ATE186575T1 (de) Verfahren zur identifizierung von menschlichen und tierischen zellen mit der fähigkeit zu unbegrenzter proliferation oder zur tumorbildung
ATE302413T1 (de) Schnelle bestimmung des verhältnisses von biologischen molekülen
EP0906574A4 (en) METHOD AND SETS FOR DETECTING ENDOTOXINS
DE59710105D1 (de) Verwendung von Azomagentapigment in einem elektrophotographischen Toner und Entwickler
ATE253223T1 (de) Verfahren und materialien zur diagnose instabiler angina
DE69231710D1 (de) Tyrosinkinase
DE59910326D1 (de) Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
NO992666L (no) ICAM-4 og diagnostisk anvendelse av denne
ATE41526T1 (de) Photometrische instrumente, ihre verwendung in optischen analysemethoden und dazu dienendes zubehoer.
DE69500393D1 (de) Verfahren zur identifizierung von lymphozyten mit mutator-phänotypen