PT952148E - Derivados de acido ciclobutil-ariloxiarilsulfonilamino-hidroxamico - Google Patents
Derivados de acido ciclobutil-ariloxiarilsulfonilamino-hidroxamicoInfo
- Publication number
- PT952148E PT952148E PT99302282T PT99302282T PT952148E PT 952148 E PT952148 E PT 952148E PT 99302282 T PT99302282 T PT 99302282T PT 99302282 T PT99302282 T PT 99302282T PT 952148 E PT952148 E PT 952148E
- Authority
- PT
- Portugal
- Prior art keywords
- cylobutil
- aryloxyarilsulfonylamino
- acid derivatives
- hydroxymic acid
- hydroxymic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8139298P | 1998-04-10 | 1998-04-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT952148E true PT952148E (pt) | 2004-09-30 |
Family
ID=22163854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99302282T PT952148E (pt) | 1998-04-10 | 1999-03-25 | Derivados de acido ciclobutil-ariloxiarilsulfonilamino-hidroxamico |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6156798A (pt) |
| EP (1) | EP0952148B1 (pt) |
| JP (1) | JP3626366B2 (pt) |
| AT (1) | ATE266634T1 (pt) |
| BR (1) | BR9901250A (pt) |
| CA (1) | CA2268484C (pt) |
| DE (1) | DE69917124T2 (pt) |
| DK (1) | DK0952148T3 (pt) |
| ES (1) | ES2220004T3 (pt) |
| PT (1) | PT952148E (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ336840A (en) * | 1997-02-03 | 2001-01-26 | Pfizer Prod Inc | Arylsulfonylamino hydroxamic acid derivatives useful in the treatment of tumor necrosis factor and matrix metalloproteinase mediated diseases |
| US20040072889A1 (en) * | 1997-04-21 | 2004-04-15 | Pharmacia Corporation | Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia |
| US20030225150A1 (en) * | 1997-04-21 | 2003-12-04 | Pharmacia Corporation | Method of using a COX-2 inhibitor and a topoisomerase II inhibitor as a combination therapy in the treatment of neoplasia |
| US20030013739A1 (en) * | 1998-12-23 | 2003-01-16 | Pharmacia Corporation | Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia |
| US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| US20020103141A1 (en) * | 1998-12-23 | 2002-08-01 | Mckearn John P. | Antiangiogenic combination therapy for the treatment of cancer |
| US20040053900A1 (en) * | 1998-12-23 | 2004-03-18 | Pharmacia Corporation | Method of using a COX-2 inhibitor and an aromatase inhibitor as a combination therapy |
| US20030203956A1 (en) * | 1998-12-23 | 2003-10-30 | Masterrer Jaime L. | Method of using a cyclooxygenase-2 inhibitor and one or more ornithine decarboxylase inhibitors as a combination therapy in the treatment of neoplasia |
| US20030119895A1 (en) * | 1998-12-23 | 2003-06-26 | Pharmacia Corporation | Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia |
| US6858598B1 (en) | 1998-12-23 | 2005-02-22 | G. D. Searle & Co. | Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| CA2404125C (en) * | 2000-03-20 | 2011-01-25 | Merck Sharp & Dohme Limited | Sulphonamido-substituted bridged bicycloalkyl derivatives |
| EP1191024A1 (en) * | 2000-09-22 | 2002-03-27 | Harald Tschesche | Thiadiazines and their use as inhibitors of metalloproteinases |
| BR0207297A (pt) | 2001-02-15 | 2005-04-19 | King Pharmaceuticals Inc | Composição farmacêutica em forma sólida e método de preparar uma forma de dosagem sólida de um ingrediente farmaceuticamente ativo |
| WO2003000194A2 (en) | 2001-06-21 | 2003-01-03 | Pfizer Inc. | Thienopyridine and thienopyrimidine anticancer agents |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| JPWO2003045433A1 (ja) * | 2001-11-29 | 2005-04-07 | 日本オルガノン株式会社 | 心機能不全治療薬 |
| PE20030701A1 (es) | 2001-12-20 | 2003-08-21 | Schering Corp | Compuestos para el tratamiento de trastornos inflamatorios |
| JP4313678B2 (ja) * | 2001-12-27 | 2009-08-12 | 大日本住友製薬株式会社 | ヒドロキサム酸誘導体およびそれを有効成分とするmmp阻害剤 |
| MXPA05000729A (es) * | 2002-07-17 | 2005-04-08 | Warner Lambert Co | Combinacion de un inhibidor alosterico de metaloproteinasa-13 de matriz con celecoxib o valdecoxib. |
| MXPA05000723A (es) * | 2002-07-17 | 2005-04-08 | Warner Lambert Co | Combinacion de un inhibidor alosterico de metaloproteinasa-13 de matriz con un inhibidor selectivo de ciclooxigenasa-2 que no es celecoxib o valdecoxib. |
| ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
| GB0319069D0 (en) * | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Therapeutically useful compounds |
| GB0326546D0 (en) * | 2003-11-14 | 2003-12-17 | Amersham Plc | Inhibitor imaging agents |
| ME01788B (me) | 2004-08-26 | 2011-02-28 | Pfizer | Enantiomerno čista aminoheteroaril jedinjenja kao inhibitori protein kinaza |
| EP1998760A2 (en) * | 2006-03-30 | 2008-12-10 | James E. Summerton | Non peptidic molecules for detecting and treating tumors |
| AU2007350326A1 (en) * | 2007-03-30 | 2008-10-09 | James E. Summerton | Non-peptidic molecules for detecting and treating tumors |
| EP2119690A1 (en) * | 2008-05-14 | 2009-11-18 | Academisch Medisch Centrum bij de Universiteit van Amsterdam | Radiolabelled MMP selective compounds |
| US9416132B2 (en) | 2011-07-21 | 2016-08-16 | Tolero Pharmaceuticals, Inc. | Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors |
| EP3924351B1 (en) | 2019-02-12 | 2025-05-21 | Sumitomo Pharma America, Inc. | Crystalline form of the hydrochloride salt of 2-((1r,4r)-4-((3-(3-(trifluoromethyl)phenyl) imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexyl)propan-2-ol |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5552419A (en) * | 1993-01-06 | 1996-09-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| US5863949A (en) * | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
| EA199900139A1 (ru) * | 1996-08-23 | 1999-08-26 | Пфайзер, Инк. | Производные арилсульфониламиногидроксамовой кислоты |
| KR20000049198A (ko) * | 1996-10-16 | 2000-07-25 | 윌리암 에이취 캘넌, 에곤 이 버그 | 매트릭스 메탈로프로티나아제 및 tace 억제제로서의 베타-설폰아미도 하이드록스암산 |
| HUP0002960A3 (en) * | 1997-08-08 | 2001-12-28 | Pfizer Prod Inc | Aryloxyarylsulfonylamino hydroxamic acid derivatives |
-
1999
- 1999-03-25 PT PT99302282T patent/PT952148E/pt unknown
- 1999-03-25 DE DE69917124T patent/DE69917124T2/de not_active Expired - Fee Related
- 1999-03-25 ES ES99302282T patent/ES2220004T3/es not_active Expired - Lifetime
- 1999-03-25 EP EP99302282A patent/EP0952148B1/en not_active Expired - Lifetime
- 1999-03-25 AT AT99302282T patent/ATE266634T1/de not_active IP Right Cessation
- 1999-03-25 DK DK99302282T patent/DK0952148T3/da active
- 1999-04-08 CA CA002268484A patent/CA2268484C/en not_active Expired - Fee Related
- 1999-04-09 BR BR9901250-2A patent/BR9901250A/pt not_active IP Right Cessation
- 1999-04-09 JP JP10248699A patent/JP3626366B2/ja not_active Expired - Fee Related
- 1999-04-09 US US09/290,023 patent/US6156798A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE266634T1 (de) | 2004-05-15 |
| JP3626366B2 (ja) | 2005-03-09 |
| ES2220004T3 (es) | 2004-12-01 |
| EP0952148A1 (en) | 1999-10-27 |
| BR9901250A (pt) | 2000-05-16 |
| US6156798A (en) | 2000-12-05 |
| DK0952148T3 (da) | 2004-09-20 |
| DE69917124D1 (de) | 2004-06-17 |
| JPH11322705A (ja) | 1999-11-24 |
| DE69917124T2 (de) | 2005-05-12 |
| CA2268484C (en) | 2006-02-07 |
| EP0952148B1 (en) | 2004-05-12 |
| CA2268484A1 (en) | 1999-10-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT952148E (pt) | Derivados de acido ciclobutil-ariloxiarilsulfonilamino-hidroxamico | |
| MY120235A (en) | Aryloxyarylsulfonylamino hydroxamic acid derivatives | |
| DK0623607T3 (da) | Benzofuranyl- og -thiophenyl-alkancarboxylsyrederivater | |
| GB9801690D0 (en) | Therapeutic agents | |
| NO940038D0 (no) | Arylsulfonamido-substituerte hydrokamsyrer | |
| NO20002440D0 (no) | Hydroksam- og karboksylsyrederivater med MMP- og TNF- inhiberende aktivitet | |
| DE69915004D1 (de) | 5-Oxo-pyrrolidine-2-Carbonsäure-Hydroxamidderivate | |
| ES2151156T3 (es) | Derivados de acidos n-(aroil)glicina hidroxamicos y compuestos relacionados. | |
| PT902022E (pt) | Novos derivados de benzofuranona e processo para a sua producao | |
| EP0799827A4 (en) | ACRYLAMIDE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF | |
| DK0652208T3 (da) | Phenylalkan(en)syrer | |
| ATE280767T1 (de) | Antidiabetische thiazolidindione und ihre herstellung | |
| DZ1724A1 (fr) | Nouvelles azétidinones substituées comme agents anti-inflammatoires et anti-dégénérescence. | |
| DE69623806D1 (de) | Pestizide | |
| ES2053809T3 (es) | Derivados de ciclopropano. | |
| NO904575L (no) | Benzocykloalkylaminopyridinaminer og beslektede forbindelser, mellomprodukter, fremgangsmaate for deres fremstillingog anvendelse som medikamenter. | |
| ATE146472T1 (de) | Umwandlungsverfahren von lorabef dihydrate in loracarbef monohydrate | |
| BR9800281B1 (pt) | processos para a preparação de cloro-benzoilcloretos, e de derivados de benzofenona cloro-substituìda. | |
| ES2111920T3 (es) | Clatratos de agua de piperazinilpiridinas. |