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PT92487A - PROCESS FOR THE PREPARATION OF PEPTID DERIVATIVES - Google Patents

PROCESS FOR THE PREPARATION OF PEPTID DERIVATIVES

Info

Publication number
PT92487A
PT92487A PT92487A PT9248789A PT92487A PT 92487 A PT92487 A PT 92487A PT 92487 A PT92487 A PT 92487A PT 9248789 A PT9248789 A PT 9248789A PT 92487 A PT92487 A PT 92487A
Authority
PT
Portugal
Prior art keywords
peptid
derivatives
preparation
peptid derivatives
Prior art date
Application number
PT92487A
Other languages
Portuguese (pt)
Other versions
PT92487B (en
Inventor
Rainer Albert
Eric P Krenning
Steven W J Lamberts
Janos Pless
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888828364A external-priority patent/GB8828364D0/en
Priority claimed from GB898916115A external-priority patent/GB8916115D0/en
Priority claimed from GB898916761A external-priority patent/GB8916761D0/en
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of PT92487A publication Critical patent/PT92487A/en
Publication of PT92487B publication Critical patent/PT92487B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT92487A 1988-12-05 1989-12-04 PROCESS FOR THE PREPARATION OF PEPTID DERIVATIVES PT92487B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888828364A GB8828364D0 (en) 1988-12-05 1988-12-05 Improvements in/relating to organic compounds
GB898916115A GB8916115D0 (en) 1989-07-13 1989-07-13 Improvements in or relating to organic compounds
GB898916761A GB8916761D0 (en) 1989-07-21 1989-07-21 Improvements in or relating to organic compounds

Publications (2)

Publication Number Publication Date
PT92487A true PT92487A (en) 1990-06-29
PT92487B PT92487B (en) 1996-01-31

Family

ID=27264222

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92487A PT92487B (en) 1988-12-05 1989-12-04 PROCESS FOR THE PREPARATION OF PEPTID DERIVATIVES

Country Status (24)

Country Link
JP (2) JP2726320B2 (en)
KR (1) KR0156541B1 (en)
AT (1) AT403476B (en)
AU (1) AU633859B2 (en)
BE (1) BE1002296A5 (en)
CA (1) CA2004532C (en)
CH (1) CH678329A5 (en)
DE (1) DE3991505B4 (en)
DK (1) DK175338B1 (en)
ES (1) ES2023533A6 (en)
FI (1) FI102540B (en)
FR (1) FR2639947B1 (en)
GB (1) GB2225579B (en)
HK (1) HK189995A (en)
HU (2) HUT53375A (en)
IE (1) IE62091B1 (en)
IL (1) IL92534A (en)
LU (1) LU87633A1 (en)
MY (1) MY106120A (en)
NL (1) NL194828C (en)
PT (1) PT92487B (en)
SA (1) SA96160495B1 (en)
SE (1) SE508799C2 (en)
WO (1) WO1990006949A2 (en)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer
DE3822557C2 (en) * 1987-07-10 1998-07-02 Ciba Geigy Ag Medicines containing somatostatins
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
US5700444A (en) * 1992-02-20 1997-12-23 Rhomed Incorporated Chemotactic peptide pharmaceutical applications
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
GB9004017D0 (en) * 1990-02-22 1990-04-18 Krenning Eric P Improvements in or relating to organic compounds
US5382654A (en) * 1992-02-05 1995-01-17 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
WO1992013554A1 (en) * 1991-02-08 1992-08-20 Biomeasure, Inc. Method of treating benign and malignant proliferative skin disease
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
JPH06508357A (en) * 1991-06-03 1994-09-22 マリンクロッド・メディカル・インコーポレイテッド Labeled polypeptide, its production method and use
CA2113995C (en) * 1991-08-29 2003-04-22 Edward A. Deutsch Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
ES2155447T3 (en) * 1992-01-03 2001-05-16 Rhomed Inc PHARMACEUTICAL APPLICATIONS OF METAL PEPTIDES-IONS.
US5738838A (en) * 1992-02-20 1998-04-14 Rhomed Incorporated IKVAV peptide radiopharmaceutical applications
US5556609A (en) * 1992-02-20 1996-09-17 Rhomed Incorporated YIGSR peptide radiopharmaceutical applications
US5371184A (en) * 1992-02-05 1994-12-06 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
ATE203417T1 (en) * 1992-02-05 2001-08-15 Mallinckrodt Inc RADIOACTIVE LABELED SOMATOSTATIN
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
JPH07505621A (en) * 1992-03-25 1995-06-22 マリンクロッド・インコーポレイテッド Detection and detection of tumor tissue during surgery
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US5716596A (en) * 1992-06-23 1998-02-10 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
US5620675A (en) * 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
EP0607103A3 (en) * 1993-01-12 1997-07-09 Sandoz Ltd Somatostatin analogs containing chelating groups and their radiolabeled compositions.
EP0683676A4 (en) * 1993-02-02 1998-09-30 Neorx Corp Directed biodistribution of small molecules.
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
CA2167281C (en) * 1993-07-15 2001-09-04 Richard T. Dean Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
GB9708265D0 (en) * 1997-04-24 1997-06-18 Nycomed Imaging As Contrast agents
FI965181A (en) 1996-12-20 1998-06-21 Map Medical Technologies Oy Polyalcohol peptide derivatives
DE19917713A1 (en) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Short-chain peptide-dye conjugates as contrast agents for optical diagnostics
US6630570B1 (en) 1999-04-09 2003-10-07 Insitut für Diagnostikforschung GmbH Short-chain peptide-dye conjugates as contrast media for optical diagnosis
US7175953B2 (en) 1999-04-09 2007-02-13 Institute Fuer Diagnostik Forschung Short-warp peptide-dye conjugate as contrast agent for optical diagnostic
US6685914B1 (en) 1999-09-13 2004-02-03 Bristol-Myers Squibb Pharma Company Macrocyclic chelants for metallopharmaceuticals
ATE427125T1 (en) * 2001-04-23 2009-04-15 Mallinckrodt Inc TC AND RE LABELED RADIOACTIVE GLYCOSYLATED OCTREOTIDE DERIVATIVES
WO2005018682A2 (en) 2003-08-20 2005-03-03 The Regents Of The University Of California Somatostatin analogs with inhibitory activity to growth hormone release
CN1867363B (en) * 2003-09-17 2010-05-12 得克萨斯大学体系董事会 Compositions for imaging the pancreas and uses thereof
EP2067786A1 (en) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Novel non selective analogs of somatostatin
WO2014081655A1 (en) 2012-11-21 2014-05-30 Serene Oncology, Llc Tin-1 17m comprising somatostatin receptor binding compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1222691A (en) * 1981-12-29 1987-06-09 Wilhelmus T. Goedemans Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4652519A (en) * 1983-02-03 1987-03-24 Yeda Research And Development Company Limited Bifunctional chelating agents and process for their production
US4707352A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group
DE3511206A1 (en) * 1985-03-28 1986-10-09 Sandoz-Patent-GmbH, 7850 Lörrach Polypeptide derivatives, their preparation and pharmaceutical products which contain these polypeptide derivatives
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
DE3522638A1 (en) * 1985-06-25 1987-01-08 Diamalt Ag NEW SOMATOSTATIN DERIVATIVES
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
AU593611B2 (en) * 1986-02-14 1990-02-15 Nihon Medi-Physics Co., Ltd. High molecular compounds having amino groups, and their utilization
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
HU906341D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance
CH679045A5 (en) * 1987-06-29 1991-12-13 Sandoz Ag
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
FR2638968B1 (en) * 1988-11-11 1994-10-07 Sandoz Sa NEW THERAPEUTIC USE OF SOMATOSTATIN AND ITS ANALOGS AND DERIVATIVES

Also Published As

Publication number Publication date
DE3991505B4 (en) 2006-04-20
NL194828C (en) 2003-04-03
FI102540B1 (en) 1998-12-31
JPH1095737A (en) 1998-04-14
AT403476B (en) 1998-02-25
NL194828B (en) 2002-12-02
GB2225579B (en) 1993-03-17
ATA901789A (en) 1997-07-15
FR2639947B1 (en) 1995-04-21
DK612689D0 (en) 1989-12-05
NL8902981A (en) 1990-07-02
HUT53375A (en) 1990-10-28
AU4587189A (en) 1990-06-14
CA2004532C (en) 2000-02-22
JP2726320B2 (en) 1998-03-11
WO1990006949A3 (en) 1990-07-26
FI895809A0 (en) 1989-12-04
DK612689A (en) 1990-06-06
KR900009697A (en) 1990-07-05
HU896359D0 (en) 1990-02-28
GB8927255D0 (en) 1990-01-31
IE893866L (en) 1990-06-05
ES2023533A6 (en) 1992-01-16
SE8904087L (en) 1991-06-05
MY106120A (en) 1995-03-31
SE8904087D0 (en) 1989-12-04
FI102540B (en) 1998-12-31
HK189995A (en) 1995-12-29
IL92534A (en) 1994-06-24
PT92487B (en) 1996-01-31
HU211468A9 (en) 1995-11-28
AU633859B2 (en) 1993-02-11
JP3686503B2 (en) 2005-08-24
IE62091B1 (en) 1994-12-14
CH678329A5 (en) 1991-08-30
WO1990006949A2 (en) 1990-06-28
GB2225579A (en) 1990-06-06
JPH02184698A (en) 1990-07-19
KR0156541B1 (en) 1998-10-15
FR2639947A1 (en) 1990-06-08
CA2004532A1 (en) 1990-06-05
SA96160495B1 (en) 2006-08-23
SE508799C2 (en) 1998-11-09
DK175338B1 (en) 2004-08-30
LU87633A1 (en) 1991-09-18
BE1002296A5 (en) 1990-11-20

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19951020

PC3A Transfer or assignment

Free format text: 971017 NOVARTIS AG CH