[go: up one dir, main page]

PT90530A - Processo para a preparacao de derivados do acido 1,1-dioxo-cefem-4-carbotiolico e de composicoes farmaceuticas ou veterinarias que os contem - Google Patents

Processo para a preparacao de derivados do acido 1,1-dioxo-cefem-4-carbotiolico e de composicoes farmaceuticas ou veterinarias que os contem

Info

Publication number
PT90530A
PT90530A PT90530A PT9053089A PT90530A PT 90530 A PT90530 A PT 90530A PT 90530 A PT90530 A PT 90530A PT 9053089 A PT9053089 A PT 9053089A PT 90530 A PT90530 A PT 90530A
Authority
PT
Portugal
Prior art keywords
derivatives
carbotiolic
cefem
dioxo
pharmaceutical
Prior art date
Application number
PT90530A
Other languages
English (en)
Other versions
PT90530B (pt
Inventor
Ettore Perrone
Marco Alpegiani
Pierluigi Bissolino
Piergiuseppe Orezzi
Giuseppe Cassanelli
Francesco Di Matteo
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of PT90530A publication Critical patent/PT90530A/pt
Publication of PT90530B publication Critical patent/PT90530B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
PT90530A 1988-05-13 1989-05-11 Processo para a preparacao de derivados do acido 1,1-dioxo-cefem-4-carbotiolico e de composicoes farmaceuticas ou veterinarias que os contem PT90530B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888811388A GB8811388D0 (en) 1988-05-13 1988-05-13 1,1-dioxo-cephem-4-carbothiolic acid derivatives

Publications (2)

Publication Number Publication Date
PT90530A true PT90530A (pt) 1989-11-30
PT90530B PT90530B (pt) 1994-11-30

Family

ID=10636869

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90530A PT90530B (pt) 1988-05-13 1989-05-11 Processo para a preparacao de derivados do acido 1,1-dioxo-cefem-4-carbotiolico e de composicoes farmaceuticas ou veterinarias que os contem

Country Status (19)

Country Link
US (1) US5356888A (pt)
EP (1) EP0378604B1 (pt)
JP (1) JPH02504285A (pt)
KR (1) KR0147300B1 (pt)
AU (1) AU628821B2 (pt)
DE (1) DE68913498T2 (pt)
DK (1) DK10190A (pt)
ES (1) ES2016017A6 (pt)
FI (1) FI94642C (pt)
GB (1) GB8811388D0 (pt)
GR (1) GR1002249B (pt)
HU (1) HU208141B (pt)
IE (1) IE66309B1 (pt)
IL (1) IL90231A0 (pt)
NZ (1) NZ229023A (pt)
PT (1) PT90530B (pt)
RU (1) RU2091383C1 (pt)
WO (1) WO1989010926A1 (pt)
ZA (1) ZA893569B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264429A (en) * 1989-10-06 1993-11-23 Synphar Laboratories, Inc. 2-spirocyclopropyl cephalosporin sulfone derivatives
JPH05503290A (ja) * 1989-10-06 1993-06-03 シンファー　ラボラトリーズ，インコーポレーティッド 新規２―スピロシクロプロピルセファロスポリンスルホン誘導体およびそれらの製造法
US5258377A (en) * 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems
US5446037A (en) * 1991-12-05 1995-08-29 Synphar Laboratories, Inc. 2-[(substituted) methylene]cephalosporin sulfones as antiinflammatory, antidegenerative and antithrombin agents
US5439904A (en) * 1993-12-07 1995-08-08 Synphar Laboratories, Inc. 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents
US5629306A (en) * 1994-12-09 1997-05-13 Research Corporation Technologies, Inc. 7-alkylidene cephalosporanic acid derivatives and methods of using the same
JPH11511463A (ja) * 1995-08-31 1999-10-05 スミスクライン・ビーチャム・コーポレイション インターロイキン変換酵素およびアポプトーシス
US5760027A (en) * 1996-12-06 1998-06-02 Research Corporation Technologies, Inc. Use of 7-alkylidene cephalosporins to inhibit elastase activity
US6407091B1 (en) * 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1187323A (en) * 1967-06-26 1970-04-08 Fujisawa Pharmaceutical Co Sydnone and Sydnone Imine Derivatives of 7-Aminocephalosporanic Acids and Preparation thereof
US4623645A (en) * 1983-04-18 1986-11-18 Merck & Co., Inc. Substituted cephalosporin sulfoxides as anti-inflammatory and antidegenerative agents
US4547371A (en) * 1983-04-18 1985-10-15 Merck & Co., Inc. Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
EP0124081A3 (en) * 1983-05-02 1986-11-26 Merck & Co. Inc. New substituted cephalosporin sulfones as antiinflammatory and antidegenerative agents, pharmaceutical compositions containing the same and processes for making them
US4699904A (en) * 1985-07-01 1987-10-13 Merck & Co., Inc. Tetrazolyl derivatives of β-lactams useful as elastase inhibitors
NZ222399A (en) * 1986-11-12 1991-07-26 Merck & Co Inc Cephalosporin derivatives; pharmaceutical compositions and processes for preparation
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
US5258377A (en) * 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems

Also Published As

Publication number Publication date
ZA893569B (en) 1990-01-31
GR1002249B (en) 1996-04-23
FI900145A (fi) 1990-01-11
HU208141B (en) 1993-08-30
GB8811388D0 (en) 1988-06-15
IE891550L (en) 1989-11-13
JPH02504285A (ja) 1990-12-06
DK10190A (da) 1990-01-15
EP0378604B1 (en) 1994-03-02
AU3579289A (en) 1989-11-29
RU2091383C1 (ru) 1997-09-27
ES2016017A6 (es) 1990-10-01
FI900145A0 (fi) 1990-01-11
KR0147300B1 (ko) 1998-08-17
US5356888A (en) 1994-10-18
FI94642C (fi) 1995-10-10
WO1989010926A1 (en) 1989-11-16
IE66309B1 (en) 1995-12-27
EP0378604A1 (en) 1990-07-25
PT90530B (pt) 1994-11-30
HUT54166A (en) 1991-01-28
DE68913498D1 (en) 1994-04-07
FI94642B (fi) 1995-06-30
GR890100309A (el) 1990-03-12
DK10190D0 (da) 1990-01-12
HU893631D0 (en) 1990-11-28
IL90231A0 (en) 1989-12-15
DE68913498T2 (de) 1994-06-09
NZ229023A (en) 1990-09-26
AU628821B2 (en) 1992-09-24
KR900701800A (ko) 1990-12-04

Similar Documents

Publication Publication Date Title
PT93089A (pt) Processo para a preparacao de derivados do acido propenoico e de composicoes fungicidas que os contem
PT84449B (pt) Processo para a preparacao de novos derivados 3,5-dissubstituidos do pirocatecol e de composicoes farmaceuticas que os contem
PT93094A (pt) Processo para a preparacao de 1,3-oxatiolanos substituidos e de composicoes farmaceuticas que os contem
PT89661A (pt) Processo para a preparacao de compostos pirrolicos substituidos e de composicoes farmaceuticas que os contem
PT92497A (pt) Processo para a preparacao de derivados de ureia de dipeptideos inibidores de enzimas, e de composicoes farmaceuticas que os contem
PT99671A (pt) Processo para a preparacao de heparosanos-n,o-sulfatados e de composicoes farmaceuticas que os contem
PT89497A (pt) Processo para a preparacao de compostos piperidinilicos 1,4-dissubstituidos e de composicoes farmaceuticas que os contem
PT91287A (pt) Processo de preparacao de derivados do acido indazol-3-carboxilico e de composicoes farmaceuticas que os contem
PT80921B (pt) Processo para a preparacao de derivados de 3-acilaminometil-imidazo {1,2-a} piridinas e de composicoes farmaceuticas que os contem
PT84704B (pt) Processo para a preparacao de derivados do acido tiolactam-n-acetico e de composicoes farmaceuticas que os contem
PT84460B (pt) Processo para a preparacao de derivados de ciclopropano 1,1-dissubstituidos e de composicoes farmaceuticas que os contem
PT84828B (pt) Processo para a preparacao de compostos heterociclicos triciclicos fundidos e de composicoes farmaceuticas que os contem
PT88335A (pt) Processo para a preparacao de derivados do acido 1,4-dihidro-4-oxo-3-quinolinocarboxilico e de composicoes farmaceuticas que os contem
PT84364B (pt) Processo para a preparacao de derivados do acido 1h-imidazol-5-carboxilico e de composicoes herbicidas que os contem
PT84478B (pt) Processo para a preparacao de derivados de pirazolo-{3,4-d}-pirimidina e de composicoes farmaceuticas que os contem
PT88351A (pt) Processo para a preparacao de derivados de isoxazol-beta-carbolina e de composicoes farmaceuticas que os contem
PT90530A (pt) Processo para a preparacao de derivados do acido 1,1-dioxo-cefem-4-carbotiolico e de composicoes farmaceuticas ou veterinarias que os contem
PT82901B (pt) Processo para a preparacao de derivados do acido antranilico dotados de accao terapeutica e de composicoes farmaceuticas que os contem
PT90904A (pt) Processo para a preparacao de derivados de 3-oxo-propanonitrilo triciclicos e de composicoes farmaceuticas que os contem
PT89659A (pt) Processo para a preparacao de {(5(6) (1h-azole-1-ilmetil)benzimidazole}-carbamatos e de composicoes farmaceuticas que os contem
PT84123B (pt) Processo para a preparacao de derivados substituidos do acido 4-amibo-3-hidroxibutirico e de composicoes farmaceuticas que os contem
PT89614A (pt) Processo para a preparacao de derivados dos acidos quinolonoe naftiridono-carboxilicos e de composicoes antibacterianas que os contem
PT82440B (pt) Processo para a preparacao de eteres ciclopentilicos e de composicoes farmaceuticas que os contem
PT94629A (pt) Processo para a preparacao de derivados de cromado e de composicoes farmaceuticas que os contem
PT83565B (pt) Processo para a preparacao de derivados do acido aril-heterociclil-alcoxi-acetico e de composicoes farmaceuticas que os contem

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940524

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19981130