PT82988B - Processo para a preparacao de complexos de flavanolignanos com fosfolipidos e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de complexos de flavanolignanos com fosfolipidos e de composicoes farmaceuticas que os contem

Info

Publication number: PT82988B
Authority: PT; Portugal
Prior art keywords: flavanolignan; phospholipids; complexes; preparation; pharmaceutical compositions
Prior art date: 1985-07-17

Application number

PT82988A

Other languages

English (en)

Other versions

PT82988A (en

Inventor

Giorgio Pifferi

Bruno Gabetta

Ezio Bombardelli

Original Assignee

Inverni Della Beffa Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-17

Filing date

1986-07-15

Publication date

1988-07-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11184188&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT82988(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-07-15 Application filed by Inverni Della Beffa Spa filed Critical Inverni Della Beffa Spa

1986-08-01 Publication of PT82988A publication Critical patent/PT82988A/pt

1988-07-01 Publication of PT82988B publication Critical patent/PT82988B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C07F9/106—Adducts, complexes, salts of phosphatides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)

PT82988A 1985-07-17 1986-07-15 Processo para a preparacao de complexos de flavanolignanos com fosfolipidos e de composicoes farmaceuticas que os contem PT82988B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8521602A IT1215291B (it)	1985-07-17	1985-07-17	Complessi di flavanolignani con fosfolipidi, loro preparazione e relative composizioni farmaceutiche.

Publications (2)

Publication Number	Publication Date
PT82988A PT82988A (en)	1986-08-01
PT82988B true PT82988B (pt)	1988-07-01

Family

ID=11184188

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT82988A PT82988B (pt)	1985-07-17	1986-07-15	Processo para a preparacao de complexos de flavanolignanos com fosfolipidos e de composicoes farmaceuticas que os contem

Country Status (18)

Country	Link
US (1)	US4764508A (pt)
EP (1)	EP0209038B2 (pt)
JP (1)	JPH0692399B2 (pt)
KR (1)	KR890002430B1 (pt)
AR (1)	AR241117A1 (pt)
AT (1)	ATE46513T1 (pt)
CA (1)	CA1259324A (pt)
CS (1)	CS257289B2 (pt)
DE (1)	DE3665717D1 (pt)
DK (1)	DK170804B1 (pt)
ES (1)	ES2002101A6 (pt)
FI (1)	FI82940C (pt)
GR (1)	GR861825B (pt)
HU (1)	HU197332B (pt)
IT (1)	IT1215291B (pt)
MX (1)	MX3173A (pt)
PT (1)	PT82988B (pt)
YU (1)	YU45790B (pt)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1201151B (it) *	1987-01-14	1989-01-27	Indena Spa	Complessi fosfolipidici con estratti da vitis vinifera,procedimento per la loro preparazione e composizioni che li cntengono
IT1201149B (it) *	1987-01-14	1989-01-27	Indena Spa	Complessi di bioflavonoidi con fosfolipidi,loro preparazione,uso e composizioni farmaceutici e cosmetiche
IT1222012B (it) *	1987-07-10	1990-08-31	Indena Spa	Composizioni farmaceutiche e cosmetiche contenenti complessi di flavonolignani con fosfolipidi
GB8716918D0 (en) *	1987-07-17	1987-08-26	Inverni Della Beffa Spa	Soluble derivatives of silybin
IT1241673B (it) *	1989-10-09	1994-01-27	Istituto Biochimico Italiano	Complessi di inclusione di silibinina con ciclodestrina, loro preparazione e composizioni farmaceutiche che li contengono.
IT1238684B (it) *	1990-02-09	1993-09-01	Indena Spa	Derivati del bilobalide,loro usi e formulazioni che li contegono
DK0464297T3 (da) *	1990-07-05	1995-10-09	Indena Spa	Komplekser af neolignanderivater med phospholipider, anvendelsen deraf samt farmaceutiske og kosmetiske formuleringer indeholdende disse
JP2672439B2 (ja) *	1991-09-25	1997-11-05	倉敷紡績株式会社	強化押出成形体
GB9211659D0 (en) *	1992-06-02	1992-07-15	Indena Spa	New alkaloid derivatives,their use and pharmaceutical formulations containing them
DE19501266A1 (de) *	1995-01-18	1996-07-25	Madaus Ag	Verfahren zur Herstellung von Flavano-Lignan-Zubereitungen mit verbesserter Freisetzung und Resorbierbarkeit danach erhältliche Zubereitungen und deren Verwendung zur Herstellung von Arzneimitteln
US5922757A (en) *	1996-09-30	1999-07-13	The Regents Of The University Of California	Treatment and prevention of hepatic disorders
US6218437B1 (en)	1996-09-30	2001-04-17	The Regents Of The University Of California	Treatment and prevention of hepatic disorders
ITMI20010429A1 (it) *	2001-03-02	2002-09-02	Indena Spa	Composizioni farmaceutiche e cosmetiche per la protezione della pelledai danni indotti dalle radiazioni solari
KR100385366B1 (ko) *	2001-03-05	2003-05-27	부광약품 주식회사	생체이용율을 개선한 실리마린 제제 조성물
ATE363486T1 (de)	2001-07-27	2007-06-15	Neptune Technologies & Bioress	Flavonoide und mehrfach ungesättigte fettsäuren enthaltende natürliche phospholipide maritimen ursprungs sowie deren anwendungen
CA2450770A1 (en) *	2001-08-01	2003-02-13	Altana Pharma Ag	Combination of selective cox-2 inhibitor and lung surfactant for respiratory syndrome
CZ292832B6 (cs) *	2001-08-30	2003-12-17	Ivax Pharmaceuticals S.R.O.	Způsob přípravy silymarinu se zvýšenou rozpustností
ITMI20031388A1 (it) *	2003-07-08	2005-01-09	Indena Spa	Formulazioni per il trattamento e la prevenzione di patologie della prostata.
ITMI20051942A1 (it) *	2005-10-14	2007-04-15	S I I T S R L Servizio Interna	Composizioni galattogeniche a base di silimarina
EP1837030A1 (en)	2006-03-09	2007-09-26	INDENA S.p.A.	Phospholipid complexes of curcumin having improved bioavailability
EP1844785A1 (en) *	2006-04-13	2007-10-17	Indena S.P.A.	Phospholipid complexes of olive fruits or leaves extracts having improved bioavailability
WO2009062737A1 (en) *	2007-11-15	2009-05-22	Madaus Gmbh	Silibinin component for the treatment of hepatitis
CZ300846B6 (cs) *	2008-06-26	2009-08-26	Agra Group, A. S.	Vodorozpustný prípravek na bázi flavanonol lignanu a zpusob jeho prípravy
US8337835B2 (en)	2009-04-10	2012-12-25	Washington University	Use of an endogenous ligand for peroxisome proliferator activated receptor alpha to treat liver disorders
IT1395351B1 (it)	2009-07-09	2012-09-14	Axioma Srl	Formulazioni orali ad elevata biodisponibilita' orale costituite da miscele di frazioni lipofile e idrofile ottenute a partire dalla propoli
CN104434935B (zh)	2009-10-29	2019-07-16	阿卡斯蒂制药股份有限公司	浓治疗性磷脂组合物
ITMI20121317A1 (it) *	2012-07-27	2014-01-28	Indena Spa	Composizioni per il trattamento della fatica oncologica
ITMI20121784A1 (it)	2012-10-22	2014-04-23	Velleja Res Srl	Composizioni galattogeniche a base di fosfatidilserina
ITMI20130425A1 (it) *	2013-03-20	2014-09-21	Istituto Biochimico Italiano	Composizione per il trattamento della sindrome metabolica e delle alterazioni metabolico-ossidative nei pazienti con steatoepatite non alcolica (nash)
CN103751785A (zh) *	2014-01-27	2014-04-30	江苏健佳药业有限公司	一种水飞蓟素磷脂复合物及其制备方法
CN104306332B (zh) *	2014-09-24	2017-02-15	东南大学	一种喜树碱类磷脂化合物、其药物组合物及应用
CN105983014A (zh) *	2015-03-23	2016-10-05	天士力制药集团股份有限公司	一种含有水飞蓟宾、ve和左旋肉碱的药物组合物
CN105983016B (zh) *	2015-03-23	2023-08-11	天士力医药集团股份有限公司	一种含有水飞蓟宾的药物组合
ITUB20155532A1 (it) *	2015-11-12	2017-05-12	St Biochimico Italiano Giovanni Lorenzini Spa	Formulazione farmaceutica orale comprendente silibina
IT201600105201A1 (it)	2016-10-19	2018-04-19	Nutrilinea Srl	Uso della fosfatidilserina per la prevenzione e il trattamento dei disturbi della prostata e relative composizioni farmaceutiche e nutraceutiche
WO2019070109A1 (es) *	2017-10-03	2019-04-11	Infinite Clinical Research International, S.A. De C.V.	Triconjugado para el tratamiento de diabetes mellitus
CN117715634A (zh)	2021-05-18	2024-03-15	普罗斯塔西斯有限责任公司	包含化合物的混合物的组合物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR5060M (pt) *	1965-12-22	1967-05-08
DE1767666C3 (de) *	1968-06-01	1986-07-31	Dr. Madaus & Co, 5000 Koeln	Pharmazeutische Zubereitung gegen Lebererkrankungen
DE1963318A1 (de) *	1969-12-17	1971-06-24	Schwabe Willmar Gmbh & Co	Silybinhalbester der Bernsteinsaeure und der Phthalsaeure,ihre Salze mit pharmakologisch vertraglichen Basen,Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneipraeparaten
DE2952115C2 (de) *	1979-12-22	1982-05-06	A. Nattermann & Cie GmbH, 5000 Köln	Rosmarinsäure-Phospholipid-Komplex
JPS5958354U (ja) *	1982-10-13	1984-04-16	三菱重工業株式会社	伝熱板
SE442562B (sv) *	1983-01-26	1986-01-13	Asea Ab	Sett att innesluta radioaktivt eller annat farligt avfall och en behallare for sadant avfall

1985
- 1985-07-17 IT IT8521602A patent/IT1215291B/it active
1986
- 1986-06-17 CS CS865455A patent/CS257289B2/cs not_active IP Right Cessation
- 1986-07-04 FI FI862850A patent/FI82940C/fi not_active IP Right Cessation
- 1986-07-07 DE DE8686109257T patent/DE3665717D1/de not_active Expired
- 1986-07-07 EP EP86109257A patent/EP0209038B2/en not_active Expired - Lifetime
- 1986-07-07 US US06/882,608 patent/US4764508A/en not_active Expired - Lifetime
- 1986-07-07 AT AT86109257T patent/ATE46513T1/de not_active IP Right Cessation
- 1986-07-10 CA CA000513497A patent/CA1259324A/en not_active Expired
- 1986-07-10 HU HU862864A patent/HU197332B/hu not_active IP Right Cessation
- 1986-07-14 GR GR861825A patent/GR861825B/el unknown
- 1986-07-15 PT PT82988A patent/PT82988B/pt unknown
- 1986-07-16 KR KR1019860005746A patent/KR890002430B1/ko not_active IP Right Cessation
- 1986-07-16 JP JP61167748A patent/JPH0692399B2/ja not_active Expired - Lifetime
- 1986-07-16 DK DK339086A patent/DK170804B1/da not_active IP Right Cessation
- 1986-07-16 ES ES8600342A patent/ES2002101A6/es not_active Expired
- 1986-07-17 YU YU128086A patent/YU45790B/sh unknown
- 1986-07-17 MX MX317386A patent/MX3173A/es unknown
- 1986-07-17 AR AR304532A patent/AR241117A1/es active

Also Published As

Publication number	Publication date
FI862850A (fi)	1987-01-18
EP0209038B2 (en)	1996-03-27
FI862850A0 (fi)	1986-07-04
MX3173A (es)	1993-09-01
KR870001188A (ko)	1987-03-12
US4764508A (en)	1988-08-16
CS257289B2 (en)	1988-04-15
HU197332B (en)	1989-03-28
IT1215291B (it)	1990-01-31
DE3665717D1 (en)	1989-10-26
PT82988A (en)	1986-08-01
DK339086A (da)	1987-01-18
CA1259324A (en)	1989-09-12
IT8521602A0 (it)	1985-07-17
GR861825B (en)	1986-11-18
DK170804B1 (da)	1996-01-22
DK339086D0 (da)	1986-07-16
AR241117A1 (es)	1991-11-15
AR241117A2 (es)	1991-11-15
KR890002430B1 (ko)	1989-07-03
ES2002101A6 (es)	1988-07-16
YU128086A (en)	1988-02-29
EP0209038A1 (en)	1987-01-21
EP0209038B1 (en)	1989-09-20
ATE46513T1 (de)	1989-10-15
FI82940C (fi)	1991-05-10
YU45790B (sh)	1992-07-20
FI82940B (fi)	1991-01-31
JPH0692399B2 (ja)	1994-11-16
JPS6222781A (ja)	1987-01-30
HUT44567A (en)	1988-03-28

Publication	Publication Date	Title
PT82988B (pt)	1988-07-01	Processo para a preparacao de complexos de flavanolignanos com fosfolipidos e de composicoes farmaceuticas que os contem
PT80299B (pt)	1987-10-20	Processo para a preparacao de novos acidos naftiridina- quinolina- e benzoxazina-carboxilicos com efeito antibacteriano e de composicoes farmaceuticas que os contem
PT84277B (pt)	1989-09-14	Processo para a preparacao de derivados de indolizina e de composicoes que os contem
PT89094A (pt)	1988-12-01	Processo para a preparacao de 1-aril-3-quinolina-e 1-aril-3-isoquinolina-carboxamidas e de composicoes farmaceuticas que as contem
PT81969B (pt)	1988-03-03	Processo para preparacao de 11 beta-fenil-esteroides e de composicoes farmaceuticas que os contem
PT82147B (pt)	1988-07-29	Processo para a preparacao de compostos com efeito inibitorio da 5-lipoxigenase e de composicoes farmaceuticas que os contem
PT89405B (pt)	1993-09-30	Processo para a preparacao de derivados de isoquinolina e de composicoes farmaceuticas que os contem
PT82985B (pt)	1989-01-30	Processo para a preparacao de derivados de distamicina e de composicoes farmaceuticas que os contem
PT81041B (pt)	1988-01-22	Processo para a preparacao de derivados de etilenodiamina-monoamida e de composicoes farmaceuticas que os contem
PT80363B (pt)	1987-10-20	Processo para a preparacao de derivados de fenol e de composicoes farmaceuticas que os contem
PT82307B (pt)	1988-07-29	Processo para a preparacao de derivados da 4'-demetil-4-epipodofilotoxina e de composicoes farmaceuticas que os contem
PT84187B (pt)	1989-09-14	Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem
PT84462B (pt)	1989-10-04	Rocesso para a preparacao de novos tiazois e oxazois substituidos e de composicoes farmaceuticas que os contem
PT81502B (pt)	1988-03-03	Processo para a preparacao de derivados de colecalciferol e de composicoes farmaceuticas que os contem
PT90172A (pt)	1989-11-10	Processo para a preparacao de n-benzopiranillactames insaturados e de composicoes farmaceuticas que os contem
PT83604B (pt)	1988-10-14	Processo para a preparacao de derivados da flavona e de composicoes farmaceuticas que os contem
PT83559B (pt)	1989-05-31	Processo para a preparacao de novos derivados de indol e indazol-ceto-sulfona e de composicoes farmaceuticas que os contem
PT89145A (pt)	1989-12-29	Processo para a preparacao de derivados da manumicina e de composicoes farmaceuticas que os contem
PT88351A (pt)	1989-06-30	Processo para a preparacao de derivados de isoxazol-beta-carbolina e de composicoes farmaceuticas que os contem
PT82440B (pt)	1988-03-03	Processo para a preparacao de eteres ciclopentilicos e de composicoes farmaceuticas que os contem
PT90721A (pt)	1989-12-29	Processo para a preparacao de compostos de imidazoquinoxalina e de composicoes farmaceuticas que os contem
PT82399B (pt)	1988-08-17	Processo para a preparacao de derivados de fenetanolamina e de composicoes farmaceuticas que os contem
PT82123B (pt)	1988-07-01	Processo para a preparacao de compostos cefem com propriedades bactericidas e de composicoes farmaceuticas que os contem
PT83419B (pt)	1989-05-12	Processo para a preparacao de 2-aminopurinas substituidas nas posicoes 6 e 9 e de composicoes farmaceuticas que contem estas purinas
PT82167B (pt)	1988-07-29	Processo para a preparacao de sulfureto heterociclicos e de composicoes farmceuticas que os contem