PT82461B - Processo para a preparacao de cloridrato de 1-fenil-dietil-amino-1-carbonil-2-aminometil-ciclopropano (z) - Google Patents

Processo para a preparacao de cloridrato de 1-fenil-dietil-amino-1-carbonil-2-aminometil-ciclopropano (z)

Info

Publication number: PT82461B
Authority: PT; Portugal
Prior art keywords: phenyl; dyethyl; cyclopropane; aminomethyl; carbonyl
Prior art date: 1985-04-25

Application number

PT82461A

Other languages

English (en)

Other versions

PT82461A (fr

Inventor

Bernard Bonnaud

Henri Cousse

Gilbert Mouzin

Jean-Francois Petoiseau

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-25

Filing date

1986-04-24

Publication date

1988-10-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9318686&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT82461(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-04-24 Application filed by Pf Medicament filed Critical Pf Medicament

1986-05-01 Publication of PT82461A publication Critical patent/PT82461A/pt

1988-10-14 Publication of PT82461B publication Critical patent/PT82461B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PT82461A 1985-04-25 1986-04-24 Processo para a preparacao de cloridrato de 1-fenil-dietil-amino-1-carbonil-2-aminometil-ciclopropano (z) PT82461B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8506335A FR2581059B1 (fr)	1985-04-25	1985-04-25	Procede de preparation du chlorhydrate de phenyl-1 diethyl amino carbonyl-1 aminomethyl-2 cyclopropane (z)

Publications (2)

Publication Number	Publication Date
PT82461A PT82461A (fr)	1986-05-01
PT82461B true PT82461B (pt)	1988-10-14

Family

ID=9318686

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT82461A PT82461B (pt)	1985-04-25	1986-04-24	Processo para a preparacao de cloridrato de 1-fenil-dietil-amino-1-carbonil-2-aminometil-ciclopropano (z)

Country Status (23)

Country	Link
EP (1)	EP0200638B1 (pt)
JP (1)	JPS61251650A (pt)
KR (1)	KR940006764B1 (pt)
AR (1)	AR240695A1 (pt)
AT (1)	ATE42273T1 (pt)
AU (1)	AU587613B2 (pt)
CA (1)	CA1266486A (pt)
DE (1)	DE3662877D1 (pt)
DK (1)	DK170888B1 (pt)
ES (1)	ES8704449A1 (pt)
FI (1)	FI87196C (pt)
FR (1)	FR2581059B1 (pt)
GE (1)	GEP19970789B (pt)
GR (1)	GR860980B (pt)
HU (1)	HU195182B (pt)
IE (1)	IE59015B1 (pt)
MX (1)	MX162896B (pt)
NO (1)	NO165143C (pt)
OA (1)	OA08241A (pt)
PT (1)	PT82461B (pt)
SU (1)	SU1443797A3 (pt)
YU (1)	YU44915B (pt)
ZA (1)	ZA862929B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2640972B1 (pt) *	1988-12-28	1991-04-19	Pf Medicament
EP0747348A4 (en) *	1994-02-22	1999-07-07	Asahi Chemical Ind	AMINOALKYLCYCLOPROPAN DERIVATIVES
FR2752732B1 (fr) *	1996-08-28	1998-11-20	Pf Medicament	Forme galenique a liberation prolongee de milnacipran
JP4418717B2 (ja) *	2004-06-24	2010-02-24	住友化学株式会社	（ｚ）−１−フェニル−１−ジエチルアミノカルボニル−２−アミノメチルシクロプロパン塩酸塩の製造方法
JP4828863B2 (ja) *	2005-01-28	2011-11-30	住友化学株式会社	（ｚ）−１−フェニル−１−（ｎ，ｎ−ジエチルアミノカルボニル）−２−フタルイミドメチルシクロプロパンの製造方法
WO2006132307A1 (ja)	2005-06-10	2006-12-14	Pierre Fabre Medicament S.A.	安定化されたミルナシプラン製剤
KR100772244B1 (ko) *	2005-07-20	2007-11-01	안국약품 주식회사	밀나시프란염산염의 제조방법
US20090118519A1 (en) *	2006-04-17	2009-05-07	Sumitomo Chemical Company, Limited	Production Method of Polycyclic Lactams
JP5338035B2 (ja) *	2006-04-17	2013-11-13	住友化学株式会社	多環式ラクタム類の製造方法
EP2114868A2 (en) *	2007-02-28	2009-11-11	Ranbaxy Laboratories Limited	Novel polymorphic forms of milnacipran hydrochloride
FR2941454B1 (fr)	2009-01-29	2011-04-01	Pf Medicament	Proced de synthese du (1s,2r)-milnacipran
US20100274050A1 (en) *	2009-04-23	2010-10-28	Glenmark Generics Limited	Solid milnacipran and process for the preparation of the same
EP2699539B1 (en) *	2011-04-21	2019-03-06	Emory University	Cyclopropyl derivatives and methods of use
CN103242289B (zh) *	2012-02-03	2015-01-07	暨明医药科技（苏州）有限公司	N,n-二烯丙基-(1r, 2r)-2-胺甲基-1-(2-噻吩)环丙烷酰胺盐酸盐的制备方法
WO2014009767A1 (en)	2012-07-07	2014-01-16	Micro Labs Limited	An improved process for the preparation of 1-aryl 2-aminomethyl cyclopropane carboxyamide (z) derivatives, their isomers and salts
EP2906518A4 (en)	2012-10-09	2016-07-27	California Inst Of Techn	CYCLES CATALYZED IN VIVO AND IN VITRO OLEFINCYCLOPROPANATION
FR2998892B1 (fr) *	2012-12-04	2015-01-02	Pf Medicament	Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments
CN103613513B (zh) *	2013-12-09	2016-01-20	上海现代制药股份有限公司	盐酸米那普仑中间体及其制备方法和应用
US9399762B2 (en)	2014-02-18	2016-07-26	California Institute Of Technology	Methods and systems for sulfimidation or sulfoximidation of organic molecules
CN104058992A (zh) *	2014-06-13	2014-09-24	上海现代制药股份有限公司	左旋米那普仑盐酸盐的晶型
EP3230258B1 (en)	2014-11-04	2019-06-26	Química Sintética, S.A.	Process for the preparation of (1s,2r)-milnacipran

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2508035A1 (fr) *	1981-06-23	1982-12-24	Fabre Sa Pierre	Derives d'aryl-1-aminomethyl-2 cyclopropanes carboxamides (z), leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central

1985
- 1985-04-25 FR FR8506335A patent/FR2581059B1/fr not_active Expired
1986
- 1986-04-14 GR GR860980A patent/GR860980B/el unknown
- 1986-04-17 AU AU56343/86A patent/AU587613B2/en not_active Expired
- 1986-04-18 ZA ZA862929A patent/ZA862929B/xx unknown
- 1986-04-21 IE IE105786A patent/IE59015B1/en not_active IP Right Cessation
- 1986-04-22 AT AT86400873T patent/ATE42273T1/de not_active IP Right Cessation
- 1986-04-22 YU YU655/86A patent/YU44915B/xx unknown
- 1986-04-22 NO NO861573A patent/NO165143C/no unknown
- 1986-04-22 EP EP86400873A patent/EP0200638B1/fr not_active Expired
- 1986-04-22 DE DE8686400873T patent/DE3662877D1/de not_active Expired
- 1986-04-23 KR KR1019860003133A patent/KR940006764B1/ko not_active IP Right Cessation
- 1986-04-23 CA CA000507320A patent/CA1266486A/fr not_active Expired - Lifetime
- 1986-04-24 HU HU861711A patent/HU195182B/hu unknown
- 1986-04-24 DK DK191286A patent/DK170888B1/da not_active IP Right Cessation
- 1986-04-24 PT PT82461A patent/PT82461B/pt unknown
- 1986-04-24 ES ES554321A patent/ES8704449A1/es not_active Expired
- 1986-04-24 MX MX2307A patent/MX162896B/es unknown
- 1986-04-24 SU SU864027356A patent/SU1443797A3/ru active
- 1986-04-24 JP JP61095850A patent/JPS61251650A/ja active Granted
- 1986-04-25 FI FI861755A patent/FI87196C/fi not_active IP Right Cessation
- 1986-04-25 OA OA58846A patent/OA08241A/xx unknown
- 1986-04-25 AR AR30375986A patent/AR240695A1/es active
1993
- 1993-03-04 GE GEAP1993566A patent/GEP19970789B/en unknown

Also Published As

Publication number	Publication date
AR240695A1 (es)	1990-09-28
ES8704449A1 (es)	1987-04-01
YU65586A (en)	1987-12-31
AU5634386A (en)	1986-10-30
ZA862929B (en)	1986-12-30
KR860008126A (ko)	1986-11-12
FI861755A0 (fi)	1986-04-25
KR940006764B1 (ko)	1994-07-27
GEP19970789B (en)	1997-01-28
EP0200638B1 (fr)	1989-04-19
FR2581059B1 (fr)	1988-04-22
DE3662877D1 (en)	1989-05-24
HU195182B (en)	1988-04-28
IE861057L (en)	1986-10-25
NO165143B (no)	1990-09-24
DK191286D0 (da)	1986-04-24
ATE42273T1 (de)	1989-05-15
NO861573L (no)	1986-10-27
OA08241A (fr)	1987-10-30
DK191286A (da)	1986-10-26
FI87196C (fi)	1992-12-10
GR860980B (en)	1986-08-25
YU44915B (en)	1991-04-30
FI87196B (fi)	1992-08-31
AU587613B2 (en)	1989-08-24
IE59015B1 (en)	1993-12-15
MX162896B (es)	1991-07-08
NO165143C (no)	1991-01-09
CA1266486A (fr)	1990-03-06
FR2581059A1 (fr)	1986-10-31
SU1443797A3 (ru)	1988-12-07
DK170888B1 (da)	1996-03-04
FI861755A (fi)	1986-10-26
JPS61251650A (ja)	1986-11-08
ES554321A0 (es)	1987-04-01
EP0200638A1 (fr)	1986-11-05
PT82461A (fr)	1986-05-01
JPH0567136B2 (pt)	1993-09-24
HUT40618A (en)	1987-01-28

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