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PT78865A - 8-De:methoxy steffimycinone antibacterial and intermediates - glycosidation, e.g. with amino-sugars, of the aglycone(s) produces anthracycline antitumour agents - Google Patents

8-De:methoxy steffimycinone antibacterial and intermediates - glycosidation, e.g. with amino-sugars, of the aglycone(s) produces anthracycline antitumour agents

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Publication number
PT78865A
PT78865A PT7886584A PT7886584A PT78865A PT 78865 A PT78865 A PT 78865A PT 7886584 A PT7886584 A PT 7886584A PT 7886584 A PT7886584 A PT 7886584A PT 78865 A PT78865 A PT 78865A
Authority
PT
Portugal
Prior art keywords
steffimycinone
amino
glycosidation
intermediates
sugars
Prior art date
Application number
PT7886584A
Other languages
French (fr)
Portuguese (pt)
Other versions
PT78865B (en
Original Assignee
Hoechst Sa Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Sa Lab filed Critical Hoechst Sa Lab
Priority to PT7886584A priority Critical patent/PT78865B/en
Publication of PT78865A publication Critical patent/PT78865A/en
Publication of PT78865B publication Critical patent/PT78865B/en

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Steffimycinone derivs. of formula (II), esp. (+/-) 7-epi-8-demethoxy-steffimycinone and intermediates for their prepn. are new. Antitumour agents formed by glycosidation of (II), pref. with amino-sugars, esp. (2R,4S)-9-methoxy-2-methyl 4-O-(3'-amino-2',3',6'-tridesoxy -alpha-L-lyxo-hexopyranosyl) 2,4,5,7-tetrahydroxy-3,4-dihydro -2H-naphthacene-1, 6,11-trione of formula (XII).
PT7886584A 1984-07-06 1984-07-06 NOVEL PROCESS FOR THE PREPARATION OF STEPHIMYCINONE STEPHENYCINONNEW ANALYZES THEREFROM OBTAINED NOVEL INTERMEDIATES USEFUL IN THE SYNTHESIS OF THESE COMPOUNDS USE OF THESE COMPOUNDS AS ANTBACTERIALS AND FOR THE SYNTHESIS OF ANTITUMORAL PT78865B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PT7886584A PT78865B (en) 1984-07-06 1984-07-06 NOVEL PROCESS FOR THE PREPARATION OF STEPHIMYCINONE STEPHENYCINONNEW ANALYZES THEREFROM OBTAINED NOVEL INTERMEDIATES USEFUL IN THE SYNTHESIS OF THESE COMPOUNDS USE OF THESE COMPOUNDS AS ANTBACTERIALS AND FOR THE SYNTHESIS OF ANTITUMORAL

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT7886584A PT78865B (en) 1984-07-06 1984-07-06 NOVEL PROCESS FOR THE PREPARATION OF STEPHIMYCINONE STEPHENYCINONNEW ANALYZES THEREFROM OBTAINED NOVEL INTERMEDIATES USEFUL IN THE SYNTHESIS OF THESE COMPOUNDS USE OF THESE COMPOUNDS AS ANTBACTERIALS AND FOR THE SYNTHESIS OF ANTITUMORAL

Publications (2)

Publication Number Publication Date
PT78865A true PT78865A (en) 1984-08-01
PT78865B PT78865B (en) 1986-09-15

Family

ID=20083515

Family Applications (1)

Application Number Title Priority Date Filing Date
PT7886584A PT78865B (en) 1984-07-06 1984-07-06 NOVEL PROCESS FOR THE PREPARATION OF STEPHIMYCINONE STEPHENYCINONNEW ANALYZES THEREFROM OBTAINED NOVEL INTERMEDIATES USEFUL IN THE SYNTHESIS OF THESE COMPOUNDS USE OF THESE COMPOUNDS AS ANTBACTERIALS AND FOR THE SYNTHESIS OF ANTITUMORAL

Country Status (1)

Country Link
PT (1) PT78865B (en)

Also Published As

Publication number Publication date
PT78865B (en) 1986-09-15

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