PT782449E - Processo de fabrico de unidades de dosagem por granulacao humida - Google Patents

Processo de fabrico de unidades de dosagem por granulacao humida

Info

Publication number: PT782449E
Authority: PT; Portugal
Prior art keywords: pct; dosage units; humidity; manufacturing process; date
Prior art date: 1994-09-22

Application number

PT95933401T

Other languages

English (en)

Inventor

Pieter De Haan

Jocominus Antonius Ma Zwinkels

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-22

Filing date

1995-09-19

Publication date

2003-07-31

1995-09-19 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2003-07-31 Publication of PT782449E publication Critical patent/PT782449E/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Reproductive Health (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PT95933401T 1994-09-22 1995-09-19 Processo de fabrico de unidades de dosagem por granulacao humida PT782449E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP94202728		1994-09-22

Publications (1)

Publication Number	Publication Date
PT782449E true PT782449E (pt)	2003-07-31

Family

ID=8217217

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT95933401T PT782449E (pt)	1994-09-22	1995-09-19	Processo de fabrico de unidades de dosagem por granulacao humida

Country Status (23)

Country	Link
US (1)	US5916593A (pt)
EP (1)	EP0782449B1 (pt)
JP (1)	JP4334616B2 (pt)
KR (1)	KR100384264B1 (pt)
CN (1)	CN1101681C (pt)
AT (1)	ATE236639T1 (pt)
AU (1)	AU700645B2 (pt)
BR (1)	BR9509019B1 (pt)
CA (1)	CA2200754C (pt)
CZ (1)	CZ289081B6 (pt)
DE (1)	DE69530308T2 (pt)
DK (1)	DK0782449T3 (pt)
ES (1)	ES2196079T3 (pt)
FI (1)	FI118791B (pt)
HK (1)	HK1002172A1 (pt)
HU (1)	HU226619B1 (pt)
MX (1)	MX9702162A (pt)
NO (1)	NO311492B1 (pt)
NZ (1)	NZ293606A (pt)
PL (1)	PL181406B1 (pt)
PT (1)	PT782449E (pt)
RU (1)	RU2166936C2 (pt)
WO (1)	WO1996009056A1 (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0955048A1 (en) *	1998-03-12	1999-11-10	Akzo Nobel N.V.	Making dosage units using low shear granulation
IL128818A0 (en) *	1998-03-12	2000-01-31	Akzo Nobel Nv	Making dosage units using low shear granulation
AU2669700A (en) *	1999-02-24	2000-09-14	Akzo Nobel N.V.	Pharmaceutical compositions containing a crystalline form of the progestagen-(17alpha)-17-hydroxy-11-methylene-19-nor-pregna- 4,15-dien-20-yn-3-one (org 30659) and lactose
DE122009000007I2 (de) *	1999-08-31	2011-07-21	Bayer Schering Pharma	Pharmazeutische kombination von ethinylestradiol und drospirenone als empfangnisverhutendes mittel.
US6787531B1 (en) *	1999-08-31	2004-09-07	Schering Ag	Pharmaceutical composition for use as a contraceptive
EP1216713A1 (en) *	2000-12-20	2002-06-26	Schering Aktiengesellschaft	Compositions of estrogen-cyclodextrin complexes
US20030027848A1 (en) *	2001-06-15	2003-02-06	Anne Billotte	Stabilized formulations
DE10159120B4 (de) *	2001-12-01	2006-08-17	Lts Lohmann Therapie-Systeme Ag	Steroidhormonhaltige transdermale therapeutische Systeme enthaltend Propylenglycolmonocaprylat und seine Verwendung
GB0209265D0 (en) *	2002-04-23	2002-06-05	Novartis Ag	Organic compounds
TW200403075A (en) *	2002-05-29	2004-03-01	Akzo Nobel Nv	Progestagenic dosage units
EP1790347B1 (en)	2002-12-20	2014-12-24	F. Hoffmann-La Roche AG	High dose ibandronate formulation
CZ298224B6 (cs) *	2003-04-29	2007-07-25	Pliva Istrazivanje I Razvoj D.O.O.	Farmaceutická kompozice obsahující jako úcinnou látku ribavirin a zpusob její výroby
PL1670440T3 (pl) *	2003-09-29	2014-11-28	Novo Nordisk Healthcare Ag	Preparaty HRT
WO2005030176A1 (en) *	2003-09-29	2005-04-07	Novo Nordisk Femcare Ag	Improved stability of progestogen formulations
JP4412963B2 (ja) *	2003-10-10	2010-02-10	旭有機材工業株式会社	バルブ用樹脂製部材
EP1734930A2 (en) *	2004-04-09	2006-12-27	Smithkline Beecham Corporation	Low dose pharmaceutical products
US7846466B2 (en) *	2004-06-10	2010-12-07	Northwestern University	Biodegradable scaffolds and uses thereof
EP1806149A4 (en) *	2004-10-25	2012-12-05	Japan Tobacco Inc	SOLID MEDICINAL PREPARATION IMPROVED IN TERMS OF SOLUBILITY AND STABILITY AND METHOD FOR PRODUCING SAME
CN103919732A (zh) *	2005-01-21	2014-07-16	沃纳奇尔科特有限责任公司	固体剂型形式的四环素类金属络合物
EP2281556A1 (en) *	2005-02-25	2011-02-09	F. Hoffmann-La Roche AG	Tablets with improved drugs substance dispersibility
US8617597B2 (en) *	2006-07-06	2013-12-31	Bayer Intellectual Property Gmbh	Pharmaceutical composition containing a tetrahydrofolic acid
CN101489563A (zh) *	2006-07-06	2009-07-22	拜耳先灵医药股份有限公司	用于避孕和预防先天性畸形风险的药物制剂
US20090269403A1 (en) *	2008-04-24	2009-10-29	Shaked Ze Ev	Oral contraceptive dosage forms and methods of making such dosage forms
CA2732105A1 (en) *	2008-08-08	2010-02-11	Mcneil-Ppc, Inc.	Use of sucralose as a granulating agent
US8314122B2 (en) *	2008-10-09	2012-11-20	Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi	Using of organic solvents in wet granulation of moxifloxacin
US8945615B2 (en) *	2009-02-17	2015-02-03	Mylan Pharmaceuticals Inc.	Controlled release budesonide minitablets
US8945616B2 (en) *	2009-02-17	2015-02-03	Mylan Pharmaceuticals Inc.	Controlled release budesonide minitablets
JP2017001989A (ja) *	2015-06-11	2017-01-05	ニプロ株式会社	医薬組成物の製造方法及び医薬組成物
JP6759478B2 (ja) *	2019-02-13	2020-09-23	富士製薬工業株式会社	経口固形組成物、その製造方法、及びその製造方法によって得られた経口用錠剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3969502A (en) *	1972-04-14	1976-07-13	Schering Aktiengesellschaft	Method for contraception by the administration of sequential contraceptive preparations
US4956182A (en) *	1989-03-16	1990-09-11	Bristol-Myers Company	Direct compression cholestyramine tablet and solvent-free coating therefor
US5200197A (en) *	1989-11-16	1993-04-06	Alza Corporation	Contraceptive pill
US5098714A (en) *	1989-11-16	1992-03-24	Alza Corporation	Osmotic, oral dosage form for fertility control
IE71202B1 (en) *	1990-12-17	1997-02-12	Akzo Nv	Progestagen-only contraceptive
IE62665B1 (en) *	1990-12-17	1995-02-22	Akzo Nv	Contraceptive regimen
IE67345B1 (en) *	1991-03-12	1996-03-20	Akzo Nv	Low dose dry pharmaceutical preparations
DE4229820C2 (de) *	1992-09-07	1998-12-03	Jenapharm Gmbh	Pharmazeutische Zubereitung auf Gestagen-Basis
WO1994018951A1 (en) *	1993-02-23	1994-09-01	Warner-Lambert Company	A process for the preparation of substantially alcohol free pharmaceutical compositions
ATE180669T1 (de) *	1993-03-05	1999-06-15	Akzo Nobel Nv	Verwendung von pregnanderivaten zur behandlung von tumoren
ZA939565B (en) *	1993-12-21	1994-08-11	Applied Analytical Ind Inc	Method for preparing low dose pharmaceutical products.

1995
- 1995-09-19 NZ NZ293606A patent/NZ293606A/en not_active IP Right Cessation
- 1995-09-19 JP JP51058896A patent/JP4334616B2/ja not_active Expired - Fee Related
- 1995-09-19 ES ES95933401T patent/ES2196079T3/es not_active Expired - Lifetime
- 1995-09-19 CZ CZ1997899A patent/CZ289081B6/cs not_active IP Right Cessation
- 1995-09-19 EP EP95933401A patent/EP0782449B1/en not_active Expired - Lifetime
- 1995-09-19 BR BRPI9509019-3A patent/BR9509019B1/pt not_active IP Right Cessation
- 1995-09-19 DK DK95933401T patent/DK0782449T3/da active
- 1995-09-19 KR KR1019970701723A patent/KR100384264B1/ko not_active IP Right Cessation
- 1995-09-19 CA CA002200754A patent/CA2200754C/en not_active Expired - Fee Related
- 1995-09-19 HU HU9800154A patent/HU226619B1/hu not_active IP Right Cessation
- 1995-09-19 PL PL95319373A patent/PL181406B1/pl not_active IP Right Cessation
- 1995-09-19 AU AU36082/95A patent/AU700645B2/en not_active Ceased
- 1995-09-19 DE DE69530308T patent/DE69530308T2/de not_active Expired - Lifetime
- 1995-09-19 AT AT95933401T patent/ATE236639T1/de not_active IP Right Cessation
- 1995-09-19 WO PCT/EP1995/003692 patent/WO1996009056A1/en active IP Right Grant
- 1995-09-19 US US08/793,976 patent/US5916593A/en not_active Expired - Fee Related
- 1995-09-19 MX MX9702162A patent/MX9702162A/es not_active IP Right Cessation
- 1995-09-19 CN CN95195823A patent/CN1101681C/zh not_active Expired - Fee Related
- 1995-09-19 PT PT95933401T patent/PT782449E/pt unknown
- 1995-09-19 RU RU97106339/14A patent/RU2166936C2/ru not_active IP Right Cessation
1997
- 1997-03-20 FI FI971172A patent/FI118791B/fi active
- 1997-03-21 NO NO19971361A patent/NO311492B1/no not_active IP Right Cessation
1998
- 1998-02-13 HK HK98101145A patent/HK1002172A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
BR9509019A (pt)	1997-12-30
EP0782449A1 (en)	1997-07-09
DE69530308T2 (de)	2003-10-16
CA2200754A1 (en)	1996-03-28
FI971172A (fi)	1997-03-20
FI118791B (fi)	2008-03-31
CN1161650A (zh)	1997-10-08
NO971361D0 (no)	1997-03-21
HK1002172A1 (en)	1998-08-07
NO971361L (no)	1997-05-21
KR970706001A (ko)	1997-11-03
CN1101681C (zh)	2003-02-19
HUT77611A (hu)	1998-06-29
CZ289081B6 (cs)	2001-10-17
JP4334616B2 (ja)	2009-09-30
ATE236639T1 (de)	2003-04-15
WO1996009056A1 (en)	1996-03-28
JPH10505846A (ja)	1998-06-09
ES2196079T3 (es)	2003-12-16
HU226619B1 (en)	2009-04-28
EP0782449B1 (en)	2003-04-09
NO311492B1 (no)	2001-12-03
CZ89997A3 (en)	1997-09-17
DK0782449T3 (da)	2003-08-04
RU2166936C2 (ru)	2001-05-20
AU700645B2 (en)	1999-01-14
AU3608295A (en)	1996-04-09
PL319373A1 (en)	1997-08-04
KR100384264B1 (ko)	2003-08-30
FI971172A0 (fi)	1997-03-20
MX9702162A (es)	1997-06-28
PL181406B1 (pl)	2001-07-31
NZ293606A (en)	1998-06-26
BR9509019B1 (pt)	2009-01-13
US5916593A (en)	1999-06-29
CA2200754C (en)	2008-04-15
DE69530308D1 (de)	2003-05-15

Publication	Publication Date	Title
PT782449E (pt)	2003-07-31	Processo de fabrico de unidades de dosagem por granulacao humida
ATE260646T1 (de)	2004-03-15	Schnell zerfallende orale dosierungsform
BR9503386A (pt)	1996-02-27	Formulaçao farmacêutica comprimido dispersivel e processo para a fabricaçao de comprimidos dispersíveis contendo cloridrato de fluoxetina
DK0760661T3 (da)	1999-08-30	Farmaceutiske sammensætninger omfattende en opiat-antagonist og calciumsalte, deres anvendelse til behandling af endorfin-m
FI964332A (fi)	1996-10-28	Eräiden metaanibisfosfonihappojohdannaisten käyttö proteesin löystymisen ja proteesin vaelluksen estämiseen
BR9406363A (pt)	1996-02-27	Composiçao farmacêutica processo para a preparaçao da mesma uso da mesma e processo para o tratamento de doenças relacionadas com o ácido gástrico
ES2126661T3 (es)	1999-04-01	Pirazoles que tienen actividad antagonista de crf.
PT881901E (pt)	2002-09-30	Novas associacoes de principios activos contendo clopidogrel e um agente anti-trombotico
AU3254395A (en)	1996-02-22	Use of a combination product that contains a competitive progesterone antagonist and a gestagen for the production of a pharmaceutical agent for treating endometriosis or leiomyomata uteri
DK0680326T3 (da)	1997-06-23	Farmaceutisk formulering af nikotinafhængighed.
IS4553A (is)	1997-08-27	Lyfjablöndur sem innihalda mónóamín oxídasa B blokkara
ATE272628T1 (de)	2004-08-15	Substituierte gamma-phenyl-delta-lactone und deren analoge, und ihre verwendungen
AU2002231889A1 (en)	2002-08-06	Halogenated composition, method for preparing same and uses thereof
FI972434A (fi)	1997-06-09	Lamotrigiiniä sisältävä farmaseuttinen koostumus
FI963394A (fi)	1996-08-30	Yskää vastustava koostumus, joka sisältää yskää vastustavaa ainetta ja bentsydamiinia
DK0862454T3 (da)	2002-12-30	CTLA-8 i kombination med G-CSF eller med G-CSF og IL-6 og anvendelse af CTLA-8 til behandling af infektioner
ES2013342A6 (es)	1990-05-01	Procedimiento para preparar composiciones farmaceuticas a base de ingredientes seleccionados principalmente entre alcohol, fenol, polvo de cantarida, yodo y fosforo.
ES2104507A1 (es)	1997-10-01	Empleo de hidrolizado de gelatina para preparar una composicion farmaceutica destinada a la prevencion y tratamiento de la displasia de cadera en perros.