[go: up one dir, main page]

PT3604324T - Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena - Google Patents

Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena

Info

Publication number
PT3604324T
PT3604324T PT191815315T PT19181531T PT3604324T PT 3604324 T PT3604324 T PT 3604324T PT 191815315 T PT191815315 T PT 191815315T PT 19181531 T PT19181531 T PT 19181531T PT 3604324 T PT3604324 T PT 3604324T
Authority
PT
Portugal
Prior art keywords
contaminant
methods
ion exchange
exchange membrane
membrane chromatography
Prior art date
Application number
PT191815315T
Other languages
English (en)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39899038&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3604324(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PT3604324T publication Critical patent/PT3604324T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT191815315T 2008-08-14 2008-08-14 Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena PT3604324T (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP14189582.1A EP2848625B1 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography
EP19181531.5A EP3604324B1 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography
EP08797895.3A EP2321337B2 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using protein displacement ion exchange membrane chromatography
PCT/US2008/073179 WO2010019148A1 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography

Publications (1)

Publication Number Publication Date
PT3604324T true PT3604324T (pt) 2024-05-10

Family

ID=39899038

Family Applications (2)

Application Number Title Priority Date Filing Date
PT191815315T PT3604324T (pt) 2008-08-14 2008-08-14 Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena
PT141895821T PT2848625T (pt) 2008-08-14 2008-08-14 Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena.

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT141895821T PT2848625T (pt) 2008-08-14 2008-08-14 Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena.

Country Status (22)

Country Link
US (2) US10927144B2 (pt)
EP (3) EP2848625B1 (pt)
JP (1) JP5666447B2 (pt)
KR (3) KR101843915B1 (pt)
CN (1) CN102149724B (pt)
AU (1) AU2008360625C1 (pt)
BR (1) BRPI0823046B1 (pt)
CA (1) CA2731943C (pt)
CY (1) CY1122221T1 (pt)
DK (2) DK2848625T3 (pt)
ES (3) ES2978373T3 (pt)
FI (1) FI3604324T3 (pt)
HR (2) HRP20240472T1 (pt)
HU (2) HUE066562T2 (pt)
IL (2) IL210912B (pt)
LT (2) LT2848625T (pt)
MX (1) MX2011001506A (pt)
PL (2) PL2848625T3 (pt)
PT (2) PT3604324T (pt)
RS (1) RS59232B1 (pt)
SI (2) SI2848625T1 (pt)
WO (1) WO2010019148A1 (pt)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2842964A1 (en) 2006-09-13 2008-03-20 Abbvie Inc. Cell culture improvements
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
PT3604324T (pt) 2008-08-14 2024-05-10 Genentech Inc Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena
WO2010048192A2 (en) * 2008-10-20 2010-04-29 Abbott Laboratories Viral inactivation during purification of antibodies
RU2520838C2 (ru) 2008-10-20 2014-06-27 Эббви Инк Выделение и очистка антител с использованием аффинной хроматографии на основе белка а
CN107365346A (zh) 2010-05-25 2017-11-21 弗·哈夫曼-拉罗切有限公司 纯化多肽的方法
WO2012030512A1 (en) * 2010-09-03 2012-03-08 Percivia Llc. Flow-through protein purification process
CN103384677A (zh) * 2010-12-10 2013-11-06 特蕾西·汤普森 用于分离方法的组合物
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
RU2648999C2 (ru) * 2011-12-22 2018-03-29 Дженентек, Инк. Способы повышения эффективности этапов очистки белка, находящихся ниже по потоку, с использованием мембранной ионообменной хроматографии
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
US10112971B2 (en) * 2013-02-26 2018-10-30 Agency For Science, Technology And Research Protein purification in the presence of nonionic organic polymers and electropositive surfaces
SG11201507230PA (en) 2013-03-12 2015-10-29 Abbvie Inc Human antibodies that bind human tnf-alpha and methods of preparing the same
US10023608B1 (en) 2013-03-13 2018-07-17 Amgen Inc. Protein purification methods to remove impurities
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
JP6163541B2 (ja) * 2013-04-16 2017-07-12 旭化成メディカル株式会社 抗体タンパク質の精製方法
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
US9546208B2 (en) 2014-01-03 2017-01-17 Bio-Rad Laboratories, Inc. Removal of impurities from protein A eluates
SG11201901059QA (en) * 2016-09-07 2019-03-28 Glaxosmithkline Ip Dev Ltd Methods for purifying antibodies
US11446613B2 (en) 2016-09-09 2022-09-20 3M Innovative Properties Company Functionalized copolymers and use thereof
US10053368B1 (en) * 2017-09-07 2018-08-21 Chevron U.S.A. Inc. Synthesis of AFX framework type molecular sieves
EP3546475A1 (en) * 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
TWI903214B (zh) * 2018-05-02 2025-11-01 美商里珍納龍藥品有限公司 用於評估生化過濾器的適合性的方法
WO2019246153A1 (en) * 2018-06-19 2019-12-26 Bristol-Myers Squibb Company Methods of purifying proteins using chromatography
CN109324143B (zh) * 2018-10-19 2021-10-29 张骐 利用二维液相分离制备抗体类产品相关杂质的方法
CN109806916B (zh) * 2019-03-15 2021-12-21 中科森辉微球技术（苏州）有限公司 高性能阴离子交换介质及其制备方法
GB201911685D0 (en) * 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying monoclonal antibodies
KR20220112014A (ko) 2021-02-03 2022-08-10 고인석 십전대보탕을 이용하여 만든 오리목뼈 간식
KR20240128671A (ko) * 2021-10-27 2024-08-26 플라즈마 테크놀로지스, 엘엘씨 단백질을 단리하기 위한 조성물 및 방법(compositions and methods for isolating proteins)
CN118290514B (zh) * 2024-06-05 2025-04-04 东曜药业有限公司 基于阴离子膜的抗体偶联药物的纯化方法及抗体偶联药物

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
USRE30985E (en) 1978-01-01 1982-06-29 Serum-free cell culture media
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
US4347322A (en) 1981-01-12 1982-08-31 Nabisco Brands, Inc. Chromatographic process for enzyme purification
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DD266710A3 (de) 1983-06-06 1989-04-12 Ve Forschungszentrum Biotechnologie Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
US5091178A (en) 1986-02-21 1992-02-25 Oncogen Tumor therapy with biologically active anti-tumor antibodies
US4927762A (en) 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
US5091313A (en) 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
US5720937A (en) 1988-01-12 1998-02-24 Genentech, Inc. In vivo tumor detection assay
JP2749167B2 (ja) 1988-06-21 1998-05-13 ジェネンテク，インコーポレイテッド 心筋梗塞の処置のための方法および治療用組成物
EP0435911B1 (en) 1988-09-23 1996-03-13 Cetus Oncology Corporation Cell culture medium for enhanced cell growth, culture longevity and product expression
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
EP0402226A1 (en) 1989-06-06 1990-12-12 Institut National De La Recherche Agronomique Transformation vectors for yeast yarrowia
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
DK0602126T3 (da) 1991-08-14 2003-06-16 Genentech Inc Immunoglobulinvarianter til specifikke FC epsilon-receptorer
WO1993011161A1 (en) 1991-11-25 1993-06-10 Enzon, Inc. Multivalent antigen-binding proteins
DE69334351D1 (de) 1992-02-06 2011-05-12 Novartis Vaccines & Diagnostic Biosynthetisches Bindeprotein für Tumormarker
JPH08500826A (ja) 1992-08-21 1996-01-30 ジェネンテク，インコーポレイテッド Ｌｆａ−１仲介疾患を処置する方法
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
US5595721A (en) 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
CA2106612C (en) 1993-09-21 2001-02-06 Diana Pliura Displacement chromatography process
ES2108566T3 (es) 1993-12-10 1997-12-16 Genentech Inc Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos.
AP660A (en) 1994-01-18 1998-08-18 Genentech Inc A method of treatment of parasitic infection using IgE antagonists.
JP3780315B2 (ja) 1994-03-03 2006-05-31 ジェネンテク・インコーポレイテッド 炎症性疾患の処置のための抗ｉｌ−８モノクローナル抗体
US5534615A (en) 1994-04-25 1996-07-09 Genentech, Inc. Cardiac hypertrophy factor and uses therefor
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
JPH11507535A (ja) 1995-06-07 1999-07-06 イムクローン システムズ インコーポレイテッド 腫瘍の成長を抑制する抗体および抗体フラグメント類
CA2242414C (en) 1996-01-23 2012-01-03 Genentech, Inc. Anti-cd18 antibodies for use against stroke
US6592905B1 (en) 1996-01-31 2003-07-15 Massey University Production of an immunoglobulin enriched fraction from whey protein solutions
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
KR100532178B1 (ko) 1996-11-27 2005-12-01 제넨테크, 인크. 인간화 항-ＣＤ11ａ 항체
CN100480269C (zh) 1997-04-07 2009-04-22 基因技术股份有限公司 抗-血管内皮生长因子的抗体
JP2001511653A (ja) 1997-05-15 2001-08-14 ジェネンテク，インコーポレイテッド Ａｐｏ−２レセプター
KR101036414B1 (ko) * 1998-05-06 2011-05-23 제넨테크, 인크. 이온 교환 크로마토그래피에 의한 단백질 정제 방법
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
NZ518477A (en) 1999-10-29 2004-10-29 Genentech Inc Isolated anti-prostate stem cell antigen (PSCA) antibodies that internalise upon binding to PSCA on a mammalian cell, including a PSCA-expressing tumour cell, in vivo
US6479636B1 (en) * 2000-04-11 2002-11-12 Honiron Corporation (A Louisiana Corporation) Sugarcane fractioning system
US6633462B2 (en) 2000-07-13 2003-10-14 Koninklijke Philips Electronics N.V. Magnetoresistive angle sensor having several sensing elements
UA83458C2 (uk) 2000-09-18 2008-07-25 Байоджен Айдек Ма Інк. Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
GB2372464B (en) * 2001-02-22 2003-05-14 Vivascience Ltd Method of isolating a charged compound
US7321026B2 (en) 2001-06-27 2008-01-22 Skytech Technology Limited Framework-patched immunoglobulins
EP1507793A4 (en) 2001-10-17 2006-02-01 Human Genome Sciences Inc NEUTROKIN ALPHA AND NEUTROKIN ALPHA SPLICE VERSION
US20040093621A1 (en) 2001-12-25 2004-05-13 Kyowa Hakko Kogyo Co., Ltd Antibody composition which specifically binds to CD20
WO2003068821A2 (en) 2002-02-14 2003-08-21 Immunomedics, Inc. Anti-cd20 antibodies and fusion proteins thereof and methods of use
DK1501369T3 (en) † 2002-04-26 2015-09-28 Genentech Inc Non-affinity purification of proteins
DK1561756T3 (en) * 2002-09-11 2016-02-15 Chugai Pharmaceutical Co Ltd PROCEDURE FOR CLEANING PROTEIN.
ES2524694T3 (es) 2002-10-17 2014-12-11 Genmab A/S Anticuerpos monoclonales humanos contra CD20
RS20100366A (sr) 2002-12-16 2011-04-30 Genentech, Inc. Varijante imunoglobulina i njihova upotreba
KR101351122B1 (ko) 2003-05-09 2014-01-14 듀크 유니버시티 Ｃｄ２０-특이적 항체 및 이를 이용한 방법
AR044388A1 (es) 2003-05-20 2005-09-07 Applied Molecular Evolution Moleculas de union a cd20
AU2004263538B2 (en) 2003-08-08 2009-09-17 Immunomedics, Inc. Bispecific antibodies for inducing apoptosis of tumor and diseased cells
US8147832B2 (en) 2003-08-14 2012-04-03 Merck Patent Gmbh CD20-binding polypeptide compositions and methods
WO2005044856A2 (en) † 2003-10-27 2005-05-19 Wyeth Removal of high molecular weight aggregates using hydroxyapatite chromatography
WO2006086586A2 (en) * 2005-02-10 2006-08-17 Baylor Research Institute Anti-interferon alpha monoclonal antibodies and methods for use
HUE049797T2 (hu) 2005-03-11 2020-10-28 Wyeth Llc Gyenge megoszlási kromatográfiás eljárás
CN101437839A (zh) 2006-03-20 2009-05-20 米德列斯公司 蛋白质纯化
US20100075375A1 (en) 2006-10-03 2010-03-25 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
WO2009135656A1 (en) 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
PT3604324T (pt) 2008-08-14 2024-05-10 Genentech Inc Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena
WO2015198451A1 (ja) 2014-06-26 2015-12-30 楽天株式会社 情報処理装置、情報処理方法及び情報処理プログラム

Also Published As

Publication number Publication date
CA2731943C (en) 2016-11-29
KR20180033311A (ko) 2018-04-02
KR20180137591A (ko) 2018-12-27
EP2848625B1 (en) 2019-07-31
RS59232B1 (sr) 2019-10-31
ES2978373T3 (es) 2024-09-11
AU2008360625A1 (en) 2010-02-18
LT3604324T (lt) 2024-05-10
BRPI0823046A2 (pt) 2015-07-28
CN102149724A (zh) 2011-08-10
WO2010019148A1 (en) 2010-02-18
MX2011001506A (es) 2011-03-15
HRP20240472T1 (hr) 2024-06-21
EP2321337B1 (en) 2014-10-22
CN102149724B (zh) 2014-04-09
FI3604324T3 (fi) 2024-05-16
IL210912B (en) 2019-03-31
US20120122759A1 (en) 2012-05-17
US20210284685A1 (en) 2021-09-16
JP5666447B2 (ja) 2015-02-12
HUE066562T2 (hu) 2024-08-28
KR20110067099A (ko) 2011-06-21
KR101843915B1 (ko) 2018-04-02
CA2731943A1 (en) 2010-02-18
ES2527943T5 (es) 2019-03-07
SI2848625T1 (sl) 2019-11-29
EP2321337B9 (en) 2016-11-30
DK2848625T3 (da) 2019-10-07
CY1122221T1 (el) 2020-11-25
SI3604324T1 (sl) 2024-06-28
BRPI0823046B1 (pt) 2021-12-14
EP2321337B2 (en) 2018-10-10
IL210912A0 (en) 2011-04-28
PT2848625T (pt) 2019-10-25
ES2749190T3 (es) 2020-03-19
HUE047316T2 (hu) 2020-04-28
AU2008360625C1 (en) 2017-01-19
DK3604324T3 (da) 2024-04-08
JP2011530592A (ja) 2011-12-22
PL2848625T3 (pl) 2020-01-31
EP3604324A1 (en) 2020-02-05
US10927144B2 (en) 2021-02-23
EP2848625A1 (en) 2015-03-18
EP3604324B1 (en) 2024-02-28
ES2527943T3 (es) 2015-02-02
EP2321337A1 (en) 2011-05-18
PL3604324T3 (pl) 2024-07-01
IL262657A (en) 2018-12-31
HK1210181A1 (en) 2016-04-15
IL262657B (en) 2021-03-25
KR102196883B1 (ko) 2020-12-30
LT2848625T (lt) 2019-10-10
HRP20191848T1 (hr) 2019-12-27
AU2008360625B2 (en) 2016-05-19

Similar Documents

Publication Publication Date Title
IL262657B (en) Methods for removing a contaminant using natural protein transfer in ion exchange membrane chromatography
ZA201002497B (en) Method for making contact lenses
IL211217A0 (en) Methods for evaluating chromatography column performance
GB0619534D0 (en) Recap alignment clamp
EP2313172A4 (en) BLOCK CONFIGURATION FOR DISTILLATION ON LARGE SCALE MEMBRANE
EP2170479A4 (en) RECOVERY PROCESS
EP2263105A4 (en) METHOD FOR PERFORMING STRAINED POLARIZATION FILTRATION
IL205107A0 (en) Method for purifying fc-fusion proteins
EP2241095A4 (en) Techniques for transfer error recovery
EP2519536A4 (en) PROTEIN PURIFICATION BY ION EXCHANGE
IL193096A0 (en) End-cap device for high efficiency disposable chromatography column
FR2911793B1 (fr) Procede de separation par chromatographie
ZA200908352B (en) Method for cell separation
EP1979927A4 (en) REDEPOSITION TECHNIQUE FOR MEMBRANE FIXATION
EP2173770A4 (en) METHOD FOR REMOVING ENDOTOXINS FROM PROTEINS
EP2322498A4 (en) PROCESS FOR REMOVING DIBENO FUELS
PL2257537T3 (pl) Sposób oczyszczania epichlorohydryn
EP2216408A4 (en) METHOD FOR IMPROVING SALINITY TOLERANCE
GB0805298D0 (en) SAL (semi-active-laser) target-detection method
EP2005930A4 (de) Verfahren zur faltenentfernung
LT2134498T (lt) Autogeninių apdorojimų būdas
EP2129451A4 (en) METHOD FOR REMOVING STYRENE
FI20065014A0 (fi) Menetelmä betaiinin erottamiseksi
AU2008900866A0 (en) Method for Desalinating Water
AU2008904172A0 (en) Block configuration for large scale membrane distillation