PT3596080T - Derivados de pirazolo [1,5-a]pirimidina substituídos com alicíclico farmacologicamente ativos - Google Patents

Derivados de pirazolo [1,5-a]pirimidina substituídos com alicíclico farmacologicamente ativos

Info

Publication number: PT3596080T
Authority: PT; Portugal
Prior art keywords: pharmacologically active; substituted pyrazolo; active alicyclic; alicyclic; pyrazolo
Prior art date: 2017-03-13

Application number

PT18713016T

Other languages

English (en)

Original Assignee

Richter Gedeon Nyrt

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-03-13

Filing date

2018-03-12

Publication date

2021-10-22

2018-03-12 Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt

2021-10-22 Publication of PT3596080T publication Critical patent/PT3596080T/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Physical Education & Sports Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PT18713016T 2017-03-13 2018-03-12 Derivados de pirazolo [1,5-a]pirimidina substituídos com alicíclico farmacologicamente ativos PT3596080T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU1700108A HU231058B1 (hu)	2017-03-13	2017-03-13	Gyógyászatilag hatékony aliciklusos-szubsztituált pirazolo[1,5-a]pirimidin származékok

Publications (1)

Publication Number	Publication Date
PT3596080T true PT3596080T (pt)	2021-10-22

Family

ID=89992389

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT18713016T PT3596080T (pt)	2017-03-13	2018-03-12	Derivados de pirazolo [1,5-a]pirimidina substituídos com alicíclico farmacologicamente ativos

Country Status (32)

Country	Link
US (1)	US11026946B2 (pt)
EP (1)	EP3596080B1 (pt)
JP (1)	JP7153662B2 (pt)
KR (1)	KR20190127779A (pt)
CN (1)	CN110431142A (pt)
AR (1)	AR111176A1 (pt)
AU (1)	AU2018235266B2 (pt)
BR (1)	BR112019018843A2 (pt)
CA (1)	CA3056185A1 (pt)
CL (1)	CL2019002601A1 (pt)
CO (1)	CO2019010120A2 (pt)
CY (1)	CY1124708T1 (pt)
DK (1)	DK3596080T3 (pt)
EA (1)	EA038756B1 (pt)
EC (1)	ECSP19072975A (pt)
ES (1)	ES2893824T3 (pt)
GE (1)	GEP20217256B (pt)
HR (1)	HRP20211850T1 (pt)
HU (2)	HU231058B1 (pt)
IL (1)	IL268923A (pt)
LT (1)	LT3596080T (pt)
MX (1)	MX2019011000A (pt)
MY (1)	MY195262A (pt)
PE (1)	PE20191646A1 (pt)
PH (1)	PH12019501968A1 (pt)
PL (1)	PL3596080T3 (pt)
PT (1)	PT3596080T (pt)
RS (1)	RS62533B1 (pt)
SG (1)	SG11201907864YA (pt)
SI (1)	SI3596080T1 (pt)
UA (1)	UA124783C2 (pt)
WO (1)	WO2018167630A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU231057B1 (hu)	2017-03-13	2020-04-28	Richter Gedeon Nyrt	Gyógyászatilag hatékony aril-szubsztituált pirazolo[1,5-a]pirimidin származékok
RS66192B1 (sr)	2017-03-13	2024-12-31	Lundbeck La Jolla Research Center Inc	Dualni magl i faah inhibitori
TW202202495A (zh)	2020-03-26	2022-01-16	匈牙利商羅特格登公司	作為ｇａｍｍａ－胺基丁酸Ａ受體次單元ａｌｐｈａ５受體調節劑之㖠啶及吡啶并〔３，４－ｃ〕嗒𠯤衍生物
TW202220992A (zh)	2020-08-05	2022-06-01	匈牙利商羅特格登公司	具藥理活性之經雜環取代的吡唑并〔１，５－ａ〕嘧啶衍生物
HUP2100338A1 (hu)	2021-09-29	2023-04-28	Richter Gedeon Nyrt	GABAA ALFA5 receptor modulátor hatású biciklusos aminszármazékok
CN115872095A (zh) *	2022-11-28	2023-03-31	南通三鑫车灯配件有限公司	一种汽车车灯反光罩的生产线流转装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1725239B1 (en)	2004-03-02	2007-07-18	F.Hoffmann-La Roche Ag	4-(sulfanyl-pyrimidin-4-ylmethyl)-morpholine derivatives and related compounds as gaba receptor ligands for the treatment of anxiety, depression and epilepsy
GB0512844D0 (en)	2005-06-23	2005-08-03	Novartis Ag	Organic compounds
KR100753017B1 (ko) *	2006-05-25	2007-08-30	한국화학연구원	7-(3,4-디알콕시페닐)-피라졸로[1,5-ａ]피리미딘 화합물을포함하는 관절염, 아토피 피부염, 백혈병을 포함한 암 및알쯔하이머, 우울증 또는 기억력 감소 등의 뇌질환의 치료및 예방을 위한 약제학적 조성물
WO2009123986A1 (en) *	2008-03-31	2009-10-08	Takeda Pharmaceutical Company Limited	Apoptosis signal-regulating kinase 1 inhibitors
TWI648281B (zh)	2013-10-17	2019-01-21	日商安斯泰來製藥股份有限公司	含硫二環式化合物
US9828381B2 (en) *	2015-04-20	2017-11-28	AbbVie Deutschland GmbH & Co. KG	Substituted pyrazolopyrimidines and method of use
JP2018199623A (ja) *	2015-10-22	2018-12-20	大正製薬株式会社	含窒素縮合複素環化合物
HU231057B1 (hu)	2017-03-13	2020-04-28	Richter Gedeon Nyrt	Gyógyászatilag hatékony aril-szubsztituált pirazolo[1,5-a]pirimidin származékok

2017
- 2017-03-13 HU HU1700108A patent/HU231058B1/hu not_active IP Right Cessation
2018
- 2018-03-12 EP EP18713016.6A patent/EP3596080B1/en active Active
- 2018-03-12 AU AU2018235266A patent/AU2018235266B2/en not_active Ceased
- 2018-03-12 WO PCT/IB2018/051599 patent/WO2018167630A1/en active Application Filing
- 2018-03-12 BR BR112019018843A patent/BR112019018843A2/pt not_active Application Discontinuation
- 2018-03-12 PL PL18713016T patent/PL3596080T3/pl unknown
- 2018-03-12 EA EA201992127A patent/EA038756B1/ru unknown
- 2018-03-12 MX MX2019011000A patent/MX2019011000A/es unknown
- 2018-03-12 SG SG11201907864YA patent/SG11201907864YA/en unknown
- 2018-03-12 KR KR1020197028833A patent/KR20190127779A/ko not_active Ceased
- 2018-03-12 RS RS20211334A patent/RS62533B1/sr unknown
- 2018-03-12 CN CN201880017859.XA patent/CN110431142A/zh active Pending
- 2018-03-12 HR HRP20211850TT patent/HRP20211850T1/hr unknown
- 2018-03-12 PT PT18713016T patent/PT3596080T/pt unknown
- 2018-03-12 PE PE2019001773A patent/PE20191646A1/es unknown
- 2018-03-12 CA CA3056185A patent/CA3056185A1/en active Pending
- 2018-03-12 LT LTEPPCT/IB2018/051599T patent/LT3596080T/lt unknown
- 2018-03-12 MY MYPI2019004947A patent/MY195262A/en unknown
- 2018-03-12 GE GEAP201815192A patent/GEP20217256B/en unknown
- 2018-03-12 DK DK18713016.6T patent/DK3596080T3/da active
- 2018-03-12 ES ES18713016T patent/ES2893824T3/es active Active
- 2018-03-12 UA UAA201910328A patent/UA124783C2/uk unknown
- 2018-03-12 JP JP2019549366A patent/JP7153662B2/ja active Active
- 2018-03-12 US US16/493,453 patent/US11026946B2/en active Active
- 2018-03-12 HU HUE18713016A patent/HUE056562T2/hu unknown
- 2018-03-12 SI SI201830495T patent/SI3596080T1/sl unknown
- 2018-03-13 AR ARP180100580A patent/AR111176A1/es unknown
2019
- 2019-08-26 IL IL26892319A patent/IL268923A/en unknown
- 2019-08-27 PH PH12019501968A patent/PH12019501968A1/en unknown
- 2019-09-12 CL CL2019002601A patent/CL2019002601A1/es unknown
- 2019-09-18 CO CONC2019/0010120A patent/CO2019010120A2/es unknown
- 2019-10-10 EC ECSENADI201972975A patent/ECSP19072975A/es unknown
2021
- 2021-11-08 CY CY20211100964T patent/CY1124708T1/el unknown

Also Published As

Publication number	Publication date
WO2018167630A1 (en)	2018-09-20
CL2019002601A1 (es)	2020-01-24
MY195262A (en)	2023-01-11
RS62533B1 (sr)	2021-11-30
DK3596080T3 (da)	2021-11-15
MX2019011000A (es)	2019-10-17
HRP20211850T1 (hr)	2022-03-04
UA124783C2 (uk)	2021-11-17
AU2018235266B2 (en)	2021-09-30
HU231058B1 (hu)	2020-04-28
HUE056562T2 (hu)	2022-02-28
CO2019010120A2 (es)	2019-10-09
EA038756B1 (ru)	2021-10-14
AR111176A1 (es)	2019-06-12
PE20191646A1 (es)	2019-11-07
SG11201907864YA (en)	2019-09-27
IL268923A (en)	2019-10-31
JP7153662B2 (ja)	2022-10-14
EP3596080A1 (en)	2020-01-22
AU2018235266A1 (en)	2019-10-17
CA3056185A1 (en)	2018-09-20
PL3596080T3 (pl)	2022-01-31
GEP20217256B (en)	2021-05-25
BR112019018843A2 (pt)	2020-04-14
CY1124708T1 (el)	2022-07-22
ES2893824T3 (es)	2022-02-10
LT3596080T (lt)	2021-11-25
CN110431142A (zh)	2019-11-08
HUP1700108A2 (en)	2018-09-28
EP3596080B1 (en)	2021-09-01
PH12019501968A1 (en)	2020-06-29
US11026946B2 (en)	2021-06-08
SI3596080T1 (sl)	2022-01-31
US20200129515A1 (en)	2020-04-30
KR20190127779A (ko)	2019-11-13
EA201992127A1 (ru)	2020-02-06
JP2020510041A (ja)	2020-04-02
ECSP19072975A (es)	2019-11-30

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