PT3256570T - Retargeted herpesvirus with a glycoprotein h fusion - Google Patents
Retargeted herpesvirus with a glycoprotein h fusionInfo
- Publication number
- PT3256570T PT3256570T PT167045897T PT16704589T PT3256570T PT 3256570 T PT3256570 T PT 3256570T PT 167045897 T PT167045897 T PT 167045897T PT 16704589 T PT16704589 T PT 16704589T PT 3256570 T PT3256570 T PT 3256570T
- Authority
- PT
- Portugal
- Prior art keywords
- glycoprotein
- fusion
- retargeted
- herpesvirus
- retargeted herpesvirus
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 230000004927 fusion Effects 0.000 title 1
- 241001529453 unidentified herpesvirus Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/869—Herpesviral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15425012 | 2015-02-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3256570T true PT3256570T (en) | 2021-06-18 |
Family
ID=52814952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT167045897T PT3256570T (en) | 2015-02-11 | 2016-02-11 | Retargeted herpesvirus with a glycoprotein h fusion |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10421979B2 (en) |
| EP (1) | EP3256570B1 (en) |
| JP (1) | JP6751721B2 (en) |
| CN (1) | CN107406834B (en) |
| AU (1) | AU2016217906B2 (en) |
| CA (1) | CA2974868A1 (en) |
| DK (1) | DK3256570T3 (en) |
| ES (1) | ES2874584T3 (en) |
| HU (1) | HUE054563T2 (en) |
| PL (1) | PL3256570T3 (en) |
| PT (1) | PT3256570T (en) |
| RU (1) | RU2732120C2 (en) |
| WO (1) | WO2016128497A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3235908A1 (en) * | 2016-04-21 | 2017-10-25 | Ecole Normale Superieure De Lyon | Methods for selectively modulating the activity of distinct subtypes of cells |
| CN109563489A (en) | 2016-06-09 | 2019-04-02 | 大学之母博洛尼亚大学 | Herpes virus with modified glycoprotein D |
| WO2017211941A1 (en) | 2016-06-09 | 2017-12-14 | Alma Mater Studiorum Universita Di Bologna | Herpesvirus with modified glycoprotein b |
| US20210046130A1 (en) * | 2018-01-24 | 2021-02-18 | Virogin Biotech Canada Ltd | Recombinant viral vaccines |
| CA3101993A1 (en) * | 2018-05-31 | 2019-12-05 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Antigenically stealthed oncolytic viruses |
| CN108913665B (en) * | 2018-07-26 | 2021-06-22 | 江苏省农业科学院 | Hybridoma cell strain secreting anti-CpHV-1 monoclonal antibody and application thereof |
| KR20210023751A (en) * | 2019-08-22 | 2021-03-04 | 주식회사 젠셀메드 | Recombinant Herpes Simplex Virus Having Expression Cassette Expressing Fused Protein of Cancer Cell-Targeting Domain and Extracellular Damain of HVEM and Use Thereof |
| JP7573726B2 (en) * | 2020-06-12 | 2024-10-25 | ジェンセルメッド インコーポレイテッド | Recombinant herpes simplex virus containing modified glycoprotein GH for retargeting and uses thereof - Patents.com |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0714578D0 (en) | 2007-07-26 | 2007-09-05 | Crusade Lab Ltd | Viruses |
| MD20100029A (en) * | 2007-08-28 | 2010-08-31 | Universite De Liege | Recombinant koi carp herpesvirus (KHV) or Cyprinid herpesvirus 3 (CyHV-3) and vaccine to prevent KHV / CyHV-3 disease in Cyprinus carpio carpio or Cyprinus carpio koi |
| NO2700405T3 (en) | 2008-05-29 | 2018-09-01 | ||
| US9089537B2 (en) * | 2010-02-26 | 2015-07-28 | The Trustees Of The University Of Pennslyvania | Subunit vaccines for herpes viruses and methods of use |
| CN113717952A (en) * | 2013-10-28 | 2021-11-30 | 联邦高等教育系统-匹兹堡大学 | Oncolytic HSV vector |
-
2016
- 2016-02-11 PT PT167045897T patent/PT3256570T/en unknown
- 2016-02-11 AU AU2016217906A patent/AU2016217906B2/en not_active Expired - Fee Related
- 2016-02-11 EP EP16704589.7A patent/EP3256570B1/en active Active
- 2016-02-11 WO PCT/EP2016/052879 patent/WO2016128497A1/en active Application Filing
- 2016-02-11 DK DK16704589.7T patent/DK3256570T3/en active
- 2016-02-11 JP JP2017542375A patent/JP6751721B2/en active Active
- 2016-02-11 US US15/548,731 patent/US10421979B2/en active Active
- 2016-02-11 PL PL16704589T patent/PL3256570T3/en unknown
- 2016-02-11 ES ES16704589T patent/ES2874584T3/en active Active
- 2016-02-11 CA CA2974868A patent/CA2974868A1/en active Pending
- 2016-02-11 HU HUE16704589A patent/HUE054563T2/en unknown
- 2016-02-11 CN CN201680009622.8A patent/CN107406834B/en not_active Expired - Fee Related
- 2016-02-11 RU RU2017127024A patent/RU2732120C2/en active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3256570B1 (en) | 2021-03-31 |
| HUE054563T2 (en) | 2021-09-28 |
| PL3256570T3 (en) | 2021-11-29 |
| RU2732120C2 (en) | 2020-09-11 |
| RU2017127024A3 (en) | 2019-09-03 |
| JP2018512115A (en) | 2018-05-17 |
| CN107406834B (en) | 2021-03-16 |
| US20180002723A1 (en) | 2018-01-04 |
| AU2016217906B2 (en) | 2021-09-02 |
| ES2874584T3 (en) | 2021-11-05 |
| DK3256570T3 (en) | 2021-06-14 |
| RU2017127024A (en) | 2019-03-12 |
| CA2974868A1 (en) | 2016-08-18 |
| WO2016128497A1 (en) | 2016-08-18 |
| JP6751721B2 (en) | 2020-09-09 |
| US10421979B2 (en) | 2019-09-24 |
| AU2016217906A1 (en) | 2017-08-10 |
| EP3256570A1 (en) | 2017-12-20 |
| CN107406834A (en) | 2017-11-28 |
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