PT3129356T - Processo para produção de enzalutamida - Google Patents
Processo para produção de enzalutamidaInfo
- Publication number
- PT3129356T PT3129356T PT157202532T PT15720253T PT3129356T PT 3129356 T PT3129356 T PT 3129356T PT 157202532 T PT157202532 T PT 157202532T PT 15720253 T PT15720253 T PT 15720253T PT 3129356 T PT3129356 T PT 3129356T
- Authority
- PT
- Portugal
- Prior art keywords
- enzalutamide
- producing
- producing enzalutamide
- Prior art date
Links
- WXCXUHSOUPDCQV-UHFFFAOYSA-N enzalutamide Chemical compound C1=C(F)C(C(=O)NC)=CC=C1N1C(C)(C)C(=O)N(C=2C=C(C(C#N)=CC=2)C(F)(F)F)C1=S WXCXUHSOUPDCQV-UHFFFAOYSA-N 0.000 title 1
- 229960004671 enzalutamide Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ2014-232A CZ2014232A3 (cs) | 2014-04-07 | 2014-04-07 | Způsob výroby enzalutamidu |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3129356T true PT3129356T (pt) | 2020-08-28 |
Family
ID=53051699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT157202532T PT3129356T (pt) | 2014-04-07 | 2015-04-07 | Processo para produção de enzalutamida |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP3587402A1 (pt) |
| CN (1) | CN106164052A (pt) |
| CZ (1) | CZ2014232A3 (pt) |
| ES (1) | ES2806458T3 (pt) |
| PL (1) | PL3129356T3 (pt) |
| PT (1) | PT3129356T (pt) |
| WO (1) | WO2015154730A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI613194B (zh) * | 2015-06-10 | 2018-02-01 | 台灣神隆股份有限公司 | 用於製備恩雜魯胺的新穎方法 |
| CN109293544B (zh) * | 2015-08-26 | 2022-02-11 | 四川科伦药物研究院有限公司 | 恩杂鲁胺中间体化合物及其制备方法 |
| WO2017081702A2 (en) * | 2015-11-09 | 2017-05-18 | Sun Pharmaceutical Industries Limited | A process for preparation of enzalutamide |
| CN109422737B (zh) * | 2017-08-22 | 2021-07-30 | 上海时莱生物技术有限公司 | 咪唑酮类雄激素受体拮抗剂、其制备方法和用途 |
| CN109503416A (zh) * | 2018-12-24 | 2019-03-22 | 常州智超化学有限公司 | 一种恩杂鲁胺中间体合成方法 |
| EP3990435A1 (en) | 2019-06-27 | 2022-05-04 | Synthon B.V. | Process for preparation of enzalutamide |
| EP4112603A1 (en) | 2021-06-29 | 2023-01-04 | Química Sintética, S.A. | Processes for the preparation of non-steroidal antiandrogens |
| CN115703745A (zh) * | 2021-08-10 | 2023-02-17 | 中国船舶重工集团公司第七一八研究所 | 一种恩杂鲁胺的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2694290B1 (fr) * | 1992-07-08 | 1994-09-02 | Roussel Uclaf | Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant. |
| WO2006028226A1 (ja) * | 2004-09-09 | 2006-03-16 | Chugai Seiyaku Kabushiki Kaisha | 新規イミダゾリジン誘導体およびその用途 |
| NZ710355A (en) | 2005-05-13 | 2017-01-27 | Univ California | Diarylhydantoin compounds |
| PT3329775T (pt) * | 2010-02-24 | 2021-07-19 | Medivation Prostate Therapeutics Llc | Processos para a síntese de compostos de diariltiohidantoína e diarilhidantoína |
| US20170190670A1 (en) * | 2014-07-11 | 2017-07-06 | Shilpa Medicare Limited | Improved process for the preparation of enzalutamide |
| TWI613194B (zh) * | 2015-06-10 | 2018-02-01 | 台灣神隆股份有限公司 | 用於製備恩雜魯胺的新穎方法 |
-
2014
- 2014-04-07 CZ CZ2014-232A patent/CZ2014232A3/cs unknown
-
2015
- 2015-04-07 PL PL15720253T patent/PL3129356T3/pl unknown
- 2015-04-07 EP EP19020441.2A patent/EP3587402A1/en active Pending
- 2015-04-07 WO PCT/CZ2015/000032 patent/WO2015154730A1/en active Application Filing
- 2015-04-07 EP EP15720253.2A patent/EP3129356B1/en active Active
- 2015-04-07 ES ES15720253T patent/ES2806458T3/es active Active
- 2015-04-07 CN CN201580015975.4A patent/CN106164052A/zh active Pending
- 2015-04-07 PT PT157202532T patent/PT3129356T/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3129356A1 (en) | 2017-02-15 |
| EP3587402A1 (en) | 2020-01-01 |
| CN106164052A (zh) | 2016-11-23 |
| ES2806458T3 (es) | 2021-02-17 |
| WO2015154730A1 (en) | 2015-10-15 |
| EP3129356B1 (en) | 2020-06-03 |
| PL3129356T3 (pl) | 2020-11-30 |
| CZ2014232A3 (cs) | 2015-10-14 |
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