PT2773748T - Neurónios dopaminérgicos (da) do mesencéfalo para enxerto - Google Patents
Neurónios dopaminérgicos (da) do mesencéfalo para enxertoInfo
- Publication number
- PT2773748T PT2773748T PT128467156T PT12846715T PT2773748T PT 2773748 T PT2773748 T PT 2773748T PT 128467156 T PT128467156 T PT 128467156T PT 12846715 T PT12846715 T PT 12846715T PT 2773748 T PT2773748 T PT 2773748T
- Authority
- PT
- Portugal
- Prior art keywords
- neurónios
- mesencephal
- dopaminergic
- graft
- dopaminergic neurónios
- Prior art date
Links
- 230000003291 dopaminomimetic effect Effects 0.000 title 1
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
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- C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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- C12N2501/727—Kinases (EC 2.7.)
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- Health & Medical Sciences (AREA)
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- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161555828P | 2011-11-04 | 2011-11-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2773748T true PT2773748T (pt) | 2020-03-26 |
Family
ID=48192829
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT128467156T PT2773748T (pt) | 2011-11-04 | 2012-11-02 | Neurónios dopaminérgicos (da) do mesencéfalo para enxerto |
Country Status (16)
Country | Link |
---|---|
US (4) | US10280398B2 (pt) |
EP (2) | EP3693455A1 (pt) |
JP (6) | JP6461602B2 (pt) |
KR (5) | KR102426327B1 (pt) |
CN (5) | CN104379731A (pt) |
AU (4) | AU2012332269B2 (pt) |
BR (2) | BR122020000182B8 (pt) |
CA (2) | CA3177246A1 (pt) |
DK (1) | DK2773748T3 (pt) |
EA (1) | EA201490796A1 (pt) |
ES (1) | ES2779453T3 (pt) |
HK (1) | HK1201879A1 (pt) |
IL (4) | IL295556B1 (pt) |
PL (1) | PL2773748T3 (pt) |
PT (1) | PT2773748T (pt) |
WO (1) | WO2013067362A1 (pt) |
Families Citing this family (59)
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AU2012332269B2 (en) | 2011-11-04 | 2018-05-31 | Memorial Sloan-Kettering Cancer Center | Midbrain dopamine (DA) neurons for engraftment |
AU2014256876B2 (en) | 2013-04-26 | 2020-11-12 | Cornell, University | Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells |
ES2712878T3 (es) | 2013-08-06 | 2019-05-16 | Takeda Pharmaceuticals Co | Método para producir neuronas dopaminérgicas |
SG11201601720RA (en) * | 2013-09-05 | 2016-04-28 | Univ Kyoto | New method for inducing dopamine-producing neural precursor cells |
WO2015069736A1 (en) * | 2013-11-08 | 2015-05-14 | The Mclean Hospital Corporation | METHODS FOR EFFICIENT GENERATION OF GABAergic INTERNEURONS FROM PLURIPOTENT STEM CELLS |
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JP7023840B2 (ja) | 2015-10-07 | 2022-02-22 | メモリアル スローン ケタリング キャンサー センター | 神経筋接合活性のモジュレーターを同定するin vitroの方法 |
CN105567642B (zh) * | 2016-02-01 | 2019-07-12 | 中国科学院生物物理研究所 | 一种着色性干皮病人多能干细胞的制备方法 |
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US20190117782A1 (en) * | 2016-04-05 | 2019-04-25 | The Regents Of The University Of California | Cellularized hydrogels and methods of using the same |
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KR101870240B1 (ko) * | 2016-04-12 | 2018-06-22 | 서울대학교산학협력단 | 지방줄기세포에서 신경줄기세포, 신경세포 및 가바성 신경세포로의 분화 유도 방법 |
WO2017183736A1 (ja) * | 2016-04-22 | 2017-10-26 | 国立大学法人京都大学 | ドーパミン産生神経前駆細胞の製造方法 |
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EP3894556A1 (en) * | 2018-12-11 | 2021-10-20 | University of Rochester | Methods of treating schizophrenia and other neuropsychiatric disorders |
CN112011510B (zh) * | 2019-05-30 | 2023-01-03 | 中国科学院上海有机化学研究所 | 一种由人多能干细胞制备多巴胺神经元的方法 |
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