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PT2217572E - Isoquinoline modulators of atp-binding cassette transporters - Google Patents

Isoquinoline modulators of atp-binding cassette transporters Download PDF

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Publication number
PT2217572E
PT2217572E PT08849242T PT08849242T PT2217572E PT 2217572 E PT2217572 E PT 2217572E PT 08849242 T PT08849242 T PT 08849242T PT 08849242 T PT08849242 T PT 08849242T PT 2217572 E PT2217572 E PT 2217572E
Authority
PT
Portugal
Prior art keywords
isoquinoline
atp
modulators
binding cassette
cassette transporters
Prior art date
Application number
PT08849242T
Other languages
Portuguese (pt)
Inventor
Mark Miller
Peter D J Grootenhuis
Brian Bear
Jinglan Zhou
Sara Hadida Ruah
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of PT2217572E publication Critical patent/PT2217572E/en

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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PT08849242T 2007-11-16 2008-11-14 Isoquinoline modulators of atp-binding cassette transporters PT2217572E (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98855907P 2007-11-16 2007-11-16

Publications (1)

Publication Number Publication Date
PT2217572E true PT2217572E (en) 2014-02-17

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PT08849242T PT2217572E (en) 2007-11-16 2008-11-14 Isoquinoline modulators of atp-binding cassette transporters
PT121813703T PT2578571E (en) 2007-11-16 2008-11-14 Isoquinoline modulators of atp-binding cassette transporters

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PT121813703T PT2578571E (en) 2007-11-16 2008-11-14 Isoquinoline modulators of atp-binding cassette transporters

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US (4) US8507524B2 (en)
EP (3) EP2578571B1 (en)
JP (3) JP5646338B2 (en)
CN (2) CN101952254B (en)
AU (1) AU2008322616B2 (en)
CA (1) CA2705562C (en)
CY (1) CY1115318T1 (en)
DK (2) DK2217572T3 (en)
ES (3) ES2556080T3 (en)
HK (3) HK1148006A1 (en)
HR (2) HRP20140103T1 (en)
HU (1) HUE026334T2 (en)
NZ (2) NZ598941A (en)
PL (2) PL2578571T3 (en)
PT (2) PT2217572E (en)
SI (2) SI2217572T1 (en)
WO (1) WO2009064959A1 (en)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
AU2004272599A1 (en) 2003-09-06 2005-03-24 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
MXPA06005343A (en) * 2003-11-14 2006-07-10 Vertex Pharma Thiazoles and oxazoles useful as modulators of atp-binding cassette transporters.
EP3219709B1 (en) * 2004-01-30 2020-03-18 Vertex Pharmaceuticals Incorporated Intermediate compound of modulators of atp-binding cassette transporters
US7977322B2 (en) 2004-08-20 2011-07-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
DK2502911T3 (en) 2004-06-24 2017-06-06 Vertex Pharma Modulators of ATP-binding cassette transporters
CA2618057A1 (en) 2005-08-11 2007-02-22 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
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SI2578571T1 (en) 2016-01-29
EP3012250B1 (en) 2017-11-08
SI2217572T1 (en) 2014-05-30
JP2014077021A (en) 2014-05-01
HRP20151255T1 (en) 2015-12-18
US20150190390A1 (en) 2015-07-09
ES2445447T3 (en) 2014-03-03
US8722704B2 (en) 2014-05-13
WO2009064959A1 (en) 2009-05-22
CA2705562A1 (en) 2009-05-22
AU2008322616B2 (en) 2013-07-18
CY1115318T1 (en) 2017-01-04
HUE026334T2 (en) 2016-06-28
US9522145B2 (en) 2016-12-20
EP2578571A1 (en) 2013-04-10
US8507524B2 (en) 2013-08-13
HRP20140103T1 (en) 2014-05-09
DK2578571T3 (en) 2015-10-05
US20140206689A1 (en) 2014-07-24
US9012473B2 (en) 2015-04-21
EP2578571B1 (en) 2015-09-16
PT2578571E (en) 2015-11-30
CN101952254B (en) 2012-09-05

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