PT1716149E - Ácido (6s)-folínico amorfo para a preparação de soluções aquosas estáveis de (6s)-folinato de sódio ou de potássio - Google Patents

Ácido (6s)-folínico amorfo para a preparação de soluções aquosas estáveis de (6s)-folinato de sódio ou de potássio

Info

Publication number: PT1716149E
Authority: PT; Portugal
Prior art keywords: folinate; amorphous; potassium; sodium; aqueous solutions
Prior art date: 2004-02-20

Application number

PT57065146T

Other languages

English (en)

Inventor

Francese Giancarlo

Moreno Morosoli

Original Assignee

Cerbios Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-20

Filing date

2005-02-18

Publication date

2013-03-04

2005-02-18 Application filed by Cerbios Pharma Sa filed Critical Cerbios Pharma Sa

2013-03-04 Publication of PT1716149E publication Critical patent/PT1716149E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PT57065146T 2004-02-20 2005-02-18 Ácido (6s)-folínico amorfo para a preparação de soluções aquosas estáveis de (6s)-folinato de sódio ou de potássio PT1716149E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH00285/04A CH696717A5 (de)	2004-02-20	2004-02-20	Konzentrierte, stabile Losung, insbesondere eine Injektionslosung oder Infusionslosung, welche nebst Wasser entweder (6S)-Natrium-Folinat oder (6S)-Kalium-Folinat entholt

Publications (1)

Publication Number	Publication Date
PT1716149E true PT1716149E (pt)	2013-03-04

Family

ID=34866025

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT57065146T PT1716149E (pt)	2004-02-20	2005-02-18	Ácido (6s)-folínico amorfo para a preparação de soluções aquosas estáveis de (6s)-folinato de sódio ou de potássio

Country Status (10)

Country	Link
US (1)	US20080153849A1 (pt)
EP (1)	EP1716149B1 (pt)
JP (1)	JP2007523095A (pt)
AU (1)	AU2005215845B8 (pt)
CA (1)	CA2554024C (pt)
CH (1)	CH696717A5 (pt)
ES (1)	ES2267421T3 (pt)
PL (1)	PL1716149T3 (pt)
PT (1)	PT1716149E (pt)
WO (1)	WO2005080395A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE498401T1 (de) *	2004-09-15	2011-03-15	Nipro Corp	Wässrige, stabile (6s)-folinsäurelösung zur injektion
WO2010022201A2 (en) *	2008-08-22	2010-02-25	Osteogenex Inc.	Folinic acid derivatives for promoting bone growth
EP2502625A1 (en)	2011-03-21	2012-09-26	GMT Fine Chemicals SA	Process for the preparation of crystalline levofolinic acid
CN111138434A (zh) *	2019-09-18	2020-05-12	南京海纳医药科技股份有限公司	一种左亚叶酸的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4148999A (en) *	1977-08-22	1979-04-10	The Government Of The United States Of America	Preparation and purification of citrovorum factor
CH673459A5 (pt) *	1987-05-15	1990-03-15	Eprova Ag
NL8901432A (nl) *	1989-06-06	1991-01-02	Pharmachemie Bv	Bij koelkasttemperatuur stabiele waterige folinaatoplossing, alsmede werkwijze ter bereiding daarvan.
CH681303A5 (pt) *	1991-01-16	1993-02-26	Eprova Ag
IT1254635B (it) *	1992-02-20	1995-09-28	Bracco Spa	Processo per la separazione degli stereoisomeri dell'acido folinico
CH687062A5 (de) *	1994-02-14	1996-09-13	Cerbios Pharma Sa	Konzentrierte Injektionsloesung von Alkalimetallsalzen von reduzierten Folaten.
NL9400530A (nl) *	1994-04-05	1995-11-01	Pharmachemie Bv	Stabiele waterige folinaatoplossing.

2004
- 2004-02-20 CH CH00285/04A patent/CH696717A5/de not_active IP Right Cessation
2005
- 2005-02-18 AU AU2005215845A patent/AU2005215845B8/en not_active Expired
- 2005-02-18 WO PCT/CH2005/000092 patent/WO2005080395A2/de not_active Application Discontinuation
- 2005-02-18 CA CA2554024A patent/CA2554024C/en not_active Expired - Lifetime
- 2005-02-18 EP EP05706514A patent/EP1716149B1/de not_active Expired - Lifetime
- 2005-02-18 US US10/589,751 patent/US20080153849A1/en not_active Abandoned
- 2005-02-18 PT PT57065146T patent/PT1716149E/pt unknown
- 2005-02-18 ES ES05706514T patent/ES2267421T3/es not_active Expired - Lifetime
- 2005-02-18 PL PL05706514T patent/PL1716149T3/pl unknown
- 2005-02-18 JP JP2006553412A patent/JP2007523095A/ja active Pending

Also Published As

Publication number	Publication date
ES2267421T3 (es)	2013-04-16
US20080153849A1 (en)	2008-06-26
AU2005215845B8 (en)	2008-08-28
AU2005215845B2 (en)	2008-08-14
WO2005080395A2 (de)	2005-09-01
CA2554024A1 (en)	2005-09-01
WO2005080395A3 (de)	2006-02-16
EP1716149A2 (de)	2006-11-02
ES2267421T1 (es)	2007-03-16
PL1716149T3 (pl)	2013-05-31
JP2007523095A (ja)	2007-08-16
EP1716149B1 (de)	2012-12-12
AU2005215845A1 (en)	2005-09-01
CA2554024C (en)	2011-12-13
CH696717A5 (de)	2007-10-31

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