PT1701698E - Composição farmacêutica para a administração oral de cci-779 - Google Patents

Composição farmacêutica para a administração oral de cci-779 Download PDF

Info

Publication number: PT1701698E
Authority: PT; Portugal
Prior art keywords: admimistration; cci; oral; pharmaceutical composition; directly compressible
Prior art date: 2004-01-08

Application number

PT04814371T

Other languages

English (en)

Inventor

Muhammad Ashraf

Eric J Benjamin

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-08

Filing date

2004-12-14

Publication date

2008-03-27

2004-12-14 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-03-27 Publication of PT1701698E publication Critical patent/PT1701698E/pt

Links

CBPNZQVSJQDFBE-FUXHJELOSA-N Temsirolimus Chemical compound C1C[C@@H](OC(=O)C(C)(CO)CO)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 CBPNZQVSJQDFBE-FUXHJELOSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
229960000235 temsirolimus Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

PT04814371T 2004-01-08 2004-12-14 Composição farmacêutica para a administração oral de cci-779 PT1701698E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US53495104P	2004-01-08	2004-01-08

Publications (1)

Publication Number	Publication Date
PT1701698E true PT1701698E (pt)	2008-03-27

Family

ID=34806893

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT04814371T PT1701698E (pt)	2004-01-08	2004-12-14	Composição farmacêutica para a administração oral de cci-779

Country Status (31)

Country	Link
US (1)	US20050152983A1 (pt)
EP (1)	EP1701698B1 (pt)
JP (1)	JP2007517879A (pt)
KR (1)	KR20060130162A (pt)
CN (1)	CN1921861A (pt)
AR (1)	AR047180A1 (pt)
AT (1)	ATE383859T1 (pt)
AU (1)	AU2004314213A1 (pt)
BR (1)	BRPI0418373A (pt)
CA (1)	CA2552595A1 (pt)
CR (1)	CR8491A (pt)
CY (1)	CY1107373T1 (pt)
DE (1)	DE602004011398T2 (pt)
DK (1)	DK1701698T3 (pt)
EC (1)	ECSP066757A (pt)
ES (1)	ES2298861T3 (pt)
GT (1)	GT200500003A (pt)
HK (1)	HK1090308A1 (pt)
HN (1)	HN2005000005A (pt)
IL (1)	IL176519A0 (pt)
MX (1)	MXPA06007829A (pt)
NO (1)	NO20062930L (pt)
PA (1)	PA8621201A1 (pt)
PE (1)	PE20050683A1 (pt)
PL (1)	PL1701698T3 (pt)
PT (1)	PT1701698E (pt)
RU (1)	RU2006122517A (pt)
TW (1)	TW200526213A (pt)
UA (1)	UA84903C2 (pt)
WO (1)	WO2005070393A2 (pt)
ZA (1)	ZA200605631B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG145716A1 (en)	2003-09-03	2008-09-29	Wyeth Corp	Amorphous rapamycin 42-ester with 3-hydroxy-2- (hydroxymethyl)-2- methylpropionic acid and pharmaceutical compositions containing the same
US7268144B2 (en) *	2004-04-14	2007-09-11	Wyeth	Regiospecific synthesis of rapamycin 42-ester derivatives
BRPI0510277A (pt) *	2004-04-27	2007-10-30	Wyeth Corp	método para marcar especificamente uma rapamicina, rapamicina especificamente marcada, composição, e, kit
KR20070104908A (ko) *	2005-02-15	2007-10-29	와이어쓰	경구적으로 생체이용가능한 ｃｃｉ-779 정제 제형물
CA2629714A1 (en)	2005-11-14	2007-05-24	Ariad Gene Therapeutics, Inc.	Administration of an mtor inhibitor to treat patients with cancer
US9364502B2 (en) *	2006-06-28	2016-06-14	Emisphere Technologies, Inc.	Gallium nitrate formulations
US8414525B2 (en)	2006-11-20	2013-04-09	Lutonix, Inc.	Drug releasing coatings for medical devices
US8414909B2 (en)	2006-11-20	2013-04-09	Lutonix, Inc.	Drug releasing coatings for medical devices
US8414526B2 (en)	2006-11-20	2013-04-09	Lutonix, Inc.	Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US8998846B2 (en)	2006-11-20	2015-04-07	Lutonix, Inc.	Drug releasing coatings for balloon catheters
US20080276935A1 (en)	2006-11-20	2008-11-13	Lixiao Wang	Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US9700704B2 (en)	2006-11-20	2017-07-11	Lutonix, Inc.	Drug releasing coatings for balloon catheters
US9737640B2 (en)	2006-11-20	2017-08-22	Lutonix, Inc.	Drug releasing coatings for medical devices
US8425459B2 (en)	2006-11-20	2013-04-23	Lutonix, Inc.	Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US8414910B2 (en)	2006-11-20	2013-04-09	Lutonix, Inc.	Drug releasing coatings for medical devices
US8430055B2 (en)	2008-08-29	2013-04-30	Lutonix, Inc.	Methods and apparatuses for coating balloon catheters
AU2011260016B2 (en)	2010-06-02	2013-08-22	Fresenius Kabi Oncology Ltd.	Stable pharmaceutical compositions of Rapamycin esters
JP5841998B2 (ja)	2010-06-03	2016-01-13	ファーマサイクリックス，インク．	ブルトン型チロシンキナーゼ（Ｂｔｋ）の阻害剤の使用
NZ731932A (en)	2012-06-04	2018-09-28	Pharmacyclics Llc	Crystalline forms of a bruton’s tyrosine kinase inhibitor
CA2879570A1 (en)	2012-07-24	2014-01-30	Pharmacyclics, Inc.	Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk)
US10682415B2 (en)	2013-07-22	2020-06-16	Wisconsin Alumni Research Foundation	Thermogel formulation for combination drug delivery
CN104721158B (zh) *	2013-12-24	2018-01-30	正大天晴药业集团股份有限公司	一种稳定的依维莫司片剂
IL315294A (en)	2015-03-03	2024-10-01	Pharmacyclics Llc	Pharmaceutical formulations of bruton's tyrosine kinase inhibitor
US20190022073A1 (en) *	2015-09-03	2019-01-24	Nippon Kayaku Kabushiki Kaisha	Pharmaceutical composition comprising rapamycin or derivative thereof
WO2017129772A1 (en)	2016-01-29	2017-08-03	Xellia Phamaceuticals Aps	Stable pharmaceutical compositions of temsirolimus

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA737247B (en) *	1972-09-29	1975-04-30	Ayerst Mckenna & Harrison	Rapamycin and process of preparation
JP2642486B2 (ja) *	1989-08-04	1997-08-20	田辺製薬株式会社	難溶性薬物の超微粒子化法
US5536729A (en) *	1993-09-30	1996-07-16	American Home Products Corporation	Rapamycin formulations for oral administration
US5928668A (en) *	1993-12-21	1999-07-27	Applied Analytical Industries, Inc.	Method for dry blend compression of medicaments
US5362718A (en) *	1994-04-18	1994-11-08	American Home Products Corporation	Rapamycin hydroxyesters
FR2736550B1 (fr) *	1995-07-14	1998-07-24	Sandoz Sa	Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
NZ333844A (en) *	1996-08-22	2000-10-27	Res Triangle Pharm Ltd	Compositions comprising mircoparticles of water-insoluble substances and method for preparing same
US5989591A (en) *	1997-03-14	1999-11-23	American Home Products Corporation	Rapamycin formulations for oral administration
US5985325A (en) *	1997-06-13	1999-11-16	American Home Products Corporation	Rapamycin formulations for oral administration
US6277983B1 (en) *	2000-09-27	2001-08-21	American Home Products Corporation	Regioselective synthesis of rapamycin derivatives
TWI286074B (en) *	2000-11-15	2007-09-01	Wyeth Corp	Pharmaceutical composition containing CCI-779 as an antineoplastic agent
UA77200C2 (en) *	2001-08-07	2006-11-15	Wyeth Corp	Antineoplastic combination of cci-779 and bkb-569
CA2496332A1 (en) *	2002-09-17	2004-04-01	Wyeth	Oral formulations
UA83484C2 (uk) *	2003-03-05	2008-07-25	Уайт	Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція
WO2005011688A1 (en) *	2003-07-25	2005-02-10	Wyeth	Cci-779 lyophilized formulations
KR20060057605A (ko) *	2003-08-07	2006-05-26	와이어쓰	Ｃｃｉ-779의 위치선택적 합성 방법
SG145716A1 (en) *	2003-09-03	2008-09-29	Wyeth Corp	Amorphous rapamycin 42-ester with 3-hydroxy-2- (hydroxymethyl)-2- methylpropionic acid and pharmaceutical compositions containing the same
US20060142422A1 (en) *	2004-12-07	2006-06-29	Toshikazu Kobayashi	Hydrolysis resistant polyester compositions and articles made therefrom
KR20070104908A (ko) *	2005-02-15	2007-10-29	와이어쓰	경구적으로 생체이용가능한 ｃｃｉ-779 정제 제형물

2004
- 2004-12-14 DK DK04814371T patent/DK1701698T3/da active
- 2004-12-14 AT AT04814371T patent/ATE383859T1/de not_active IP Right Cessation
- 2004-12-14 DE DE602004011398T patent/DE602004011398T2/de not_active Expired - Lifetime
- 2004-12-14 KR KR1020067015655A patent/KR20060130162A/ko not_active Application Discontinuation
- 2004-12-14 ES ES04814371T patent/ES2298861T3/es not_active Expired - Lifetime
- 2004-12-14 RU RU2006122517/15A patent/RU2006122517A/ru not_active Application Discontinuation
- 2004-12-14 BR BRPI0418373-8A patent/BRPI0418373A/pt not_active IP Right Cessation
- 2004-12-14 AU AU2004314213A patent/AU2004314213A1/en not_active Abandoned
- 2004-12-14 MX MXPA06007829A patent/MXPA06007829A/es active IP Right Grant
- 2004-12-14 PT PT04814371T patent/PT1701698E/pt unknown
- 2004-12-14 CN CNA2004800399872A patent/CN1921861A/zh active Pending
- 2004-12-14 PL PL04814371T patent/PL1701698T3/pl unknown
- 2004-12-14 EP EP04814371A patent/EP1701698B1/en not_active Expired - Lifetime
- 2004-12-14 JP JP2006549291A patent/JP2007517879A/ja not_active Withdrawn
- 2004-12-14 UA UAA200608870A patent/UA84903C2/ru unknown
- 2004-12-14 CA CA002552595A patent/CA2552595A1/en not_active Abandoned
- 2004-12-14 WO PCT/US2004/042178 patent/WO2005070393A2/en active IP Right Grant
- 2004-12-27 TW TW093140750A patent/TW200526213A/zh unknown
2005
- 2005-01-04 AR ARP050100016A patent/AR047180A1/es not_active Application Discontinuation
- 2005-01-05 GT GT200500003A patent/GT200500003A/es unknown
- 2005-01-06 PE PE2005000043A patent/PE20050683A1/es not_active Application Discontinuation
- 2005-01-06 US US11/030,685 patent/US20050152983A1/en not_active Abandoned
- 2005-01-06 HN HN2005000005A patent/HN2005000005A/es unknown
- 2005-01-07 PA PA20058621201A patent/PA8621201A1/es unknown
2006
- 2006-06-22 IL IL176519A patent/IL176519A0/en unknown
- 2006-06-22 NO NO20062930A patent/NO20062930L/no not_active Application Discontinuation
- 2006-06-28 CR CR8491A patent/CR8491A/es not_active Application Discontinuation
- 2006-07-07 ZA ZA200605631A patent/ZA200605631B/xx unknown
- 2006-08-08 EC EC2006006757A patent/ECSP066757A/es unknown
- 2006-11-07 HK HK06112221A patent/HK1090308A1/xx not_active IP Right Cessation
2008
- 2008-03-31 CY CY20081100359T patent/CY1107373T1/el unknown

Also Published As

Publication number	Publication date
WO2005070393A3 (en)	2006-09-28
PA8621201A1 (es)	2005-12-23
CA2552595A1 (en)	2005-08-04
JP2007517879A (ja)	2007-07-05
HK1090308A1 (en)	2006-12-22
CR8491A (es)	2008-08-21
DE602004011398D1 (de)	2008-03-06
UA84903C2 (ru)	2008-12-10
PL1701698T3 (pl)	2008-03-31
MXPA06007829A (es)	2006-09-01
AR047180A1 (es)	2006-01-11
US20050152983A1 (en)	2005-07-14
EP1701698B1 (en)	2008-01-16
BRPI0418373A (pt)	2007-05-22
EP1701698A2 (en)	2006-09-20
PE20050683A1 (es)	2005-11-04
AU2004314213A1 (en)	2005-08-04
ZA200605631B (en)	2010-01-27
ATE383859T1 (de)	2008-02-15
CN1921861A (zh)	2007-02-28
ECSP066757A (es)	2006-11-16
NO20062930L (no)	2006-10-02
DE602004011398T2 (de)	2009-01-15
HN2005000005A (es)	2009-04-17
KR20060130162A (ko)	2006-12-18
TW200526213A (en)	2005-08-16
DK1701698T3 (da)	2008-05-05
WO2005070393A2 (en)	2005-08-04
CY1107373T1 (el)	2012-12-19
ES2298861T3 (es)	2008-05-16
IL176519A0 (en)	2006-10-05
GT200500003A (es)	2005-08-18
RU2006122517A (ru)	2008-02-20

Publication	Publication Date	Title
IL176519A0 (en)	2006-10-05	Directly compressible pharmaceutical composition for the oral administration of cci-779
IL177480A0 (en)	2006-12-10	Pharmaceutical composition
IL223545A0 (en)	2013-02-03	Pharmaceutical compositions
IL179809A0 (en)	2007-05-15	Pharmaceutical compositions
IL184114A0 (en)	2007-10-31	Use of diketodithiopiperazine antibiotics for the preparation of antiangiogenic pharmaceutical compositions
GB0408308D0 (en)	2004-05-19	Pharmaceutical compositions
IL183986A0 (en)	2007-10-31	Pharmaceutical compounds and compositions
IL180316A0 (en)	2007-07-04	Quinolone-containing medicinal composition
PL1837019T3 (pl)	2013-02-28	Kompozycja farmaceutyczna rozpadająca się w ustach
HU0401177D0 (en)	2004-08-30	Pharmaceutical composition
GB2411355B (en)	2006-02-22	Pharmaceutical composition
HK1105358A1 (en)	2008-02-15	Solid pharmaceutical formulation
EP1805154A4 (en)	2009-11-25	PHARMACEUTICAL COMPOSITIONS
ZA200701932B (en)	2008-08-27	Pharmaceutical composition
GB0425255D0 (en)	2004-12-15	Pharmaceutical composition
ZA200701931B (en)	2008-10-29	Pharmaceutical composition
ZA200603126B (en)	2007-02-28	Pharmaceutical compositions for therapeutic use
SI1701698T1 (sl)	2008-04-30	Neposredno stisljiv farmacevtski sestavek za peroralno dajanje CCI-779
GB0400971D0 (en)	2004-02-18	Pharmaceutical compositions
GB0407351D0 (en)	2004-05-05	Pharmaceutical compositions
PL373776A1 (en)	2005-10-03	Oral pharmaceutical compound
GB0411502D0 (en)	2004-06-23	Pharmaceutical compositions
GB0502792D0 (en)	2005-03-16	Pharmaceutical compositions
GB0402799D0 (en)	2004-03-10	Pharmaceutical composition
HU0300983D0 (en)	2003-06-28	Pharmaceutical composition for the preatment of diabetes