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PT1682493E - Derivados de aminoacetonitrilo - Google Patents

Derivados de aminoacetonitrilo Download PDF

Info

Publication number
PT1682493E
PT1682493E PT04797665T PT04797665T PT1682493E PT 1682493 E PT1682493 E PT 1682493E PT 04797665 T PT04797665 T PT 04797665T PT 04797665 T PT04797665 T PT 04797665T PT 1682493 E PT1682493 E PT 1682493E
Authority
PT
Portugal
Prior art keywords
amidoacetonitrile derivatives
amidoacetonitrile
derivatives
Prior art date
Application number
PT04797665T
Other languages
English (en)
Inventor
Thomas Goebel
Pierre Ducray
Noelle Gauvry
Francois Pautrat
Ronald Kaminsky
Martin Jung
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1682493E publication Critical patent/PT1682493E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT04797665T 2003-11-06 2004-11-05 Derivados de aminoacetonitrilo PT1682493E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03025290 2003-11-06
GBGB0402677.9A GB0402677D0 (en) 2003-11-06 2004-02-06 Organic compounds

Publications (1)

Publication Number Publication Date
PT1682493E true PT1682493E (pt) 2009-02-12

Family

ID=34575667

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04797665T PT1682493E (pt) 2003-11-06 2004-11-05 Derivados de aminoacetonitrilo

Country Status (22)

Country Link
US (2) US7494956B2 (pt)
EP (1) EP1682493B8 (pt)
JP (1) JP4319680B2 (pt)
KR (1) KR100793462B1 (pt)
CN (1) CN100447130C (pt)
AR (1) AR046322A1 (pt)
AT (1) ATE420066T1 (pt)
AU (1) AU2004287611B2 (pt)
BR (1) BRPI0416294B1 (pt)
CA (1) CA2544741C (pt)
DE (1) DE602004018967D1 (pt)
DK (1) DK1682493T3 (pt)
ES (1) ES2317070T3 (pt)
GB (1) GB0402677D0 (pt)
MX (1) MXPA06005036A (pt)
NZ (1) NZ546830A (pt)
PL (1) PL1682493T3 (pt)
PT (1) PT1682493E (pt)
RU (1) RU2370485C2 (pt)
SI (1) SI1682493T1 (pt)
TW (1) TWI342875B (pt)
WO (1) WO2005044784A1 (pt)

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GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
EA011764B1 (ru) 2004-03-05 2009-06-30 Ниссан Кемикал Индастриз, Лтд. Изоксазолинзамещённое производное бензамида и пестицид
EP1812385B1 (en) * 2004-11-09 2012-07-18 Novartis AG Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates
UA97388C2 (ru) * 2007-02-09 2012-02-10 Пфайзер Лімітед Противопаразитарные агенты
EP2118055B1 (en) * 2007-02-09 2013-08-21 Zoetis UK Limited Antiparasitic agents
JP5327876B2 (ja) 2007-02-21 2013-10-30 ゾエティス・ユーケイ・リミテッド ベンゾフラン抗寄生虫剤
MX2009012082A (es) 2007-05-15 2009-12-01 Merial Ltd Compuestos de ariloazol-2-il cianoetilamino, metodo para prepararlos y metodo para utilizarlos.
DK2166855T3 (en) 2007-06-07 2018-06-14 Bayer Animal Health Gmbh COMBATING Ectoparasites
ES2666187T3 (es) 2007-06-27 2018-05-03 E. I. Du Pont De Nemours And Company Procedimiento de control de plagas en animales
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
EA026649B1 (ru) 2008-10-21 2017-05-31 Мериал, Инк. Тиоамидные соединения, способ их получения и способ их применения
ES2551130T3 (es) 2008-11-14 2015-11-16 Merial, Inc. Compuestos de arilazol-2-ilcianoetilamino parasiticidas enriquecidos enantioméricamente
NZ592367A (en) 2008-12-03 2013-05-31 Novartis Ag Amidoacetonitrile compounds and pesticidal composition thereof
GB0905365D0 (en) * 2009-03-27 2009-05-13 Norbrook Lab Ltd A topical parasiticide composition
US8859003B2 (en) * 2009-06-05 2014-10-14 Intercontinental Great Brands Llc Preparation of an enteric release system
US20100307542A1 (en) * 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Method of Reducing Surface Oil on Encapsulated Material
US20100310726A1 (en) 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Novel Preparation of an Enteric Release System
US9968564B2 (en) 2009-06-05 2018-05-15 Intercontinental Great Brands Llc Delivery of functional compounds
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
UY33282A (es) * 2010-03-25 2011-09-30 Novartis Ag Composiciones endoparasiticidas
JP2014530849A (ja) 2011-10-19 2014-11-20 ゾエティス・エルエルシー 内部寄生虫に対するアミノアセトニトリル誘導体の使用
JP6165231B2 (ja) * 2012-03-23 2017-07-19 ピットニー・ファーマシューティカルズ・ピーティーワイ・リミテッド 癌の治療のためのキナーゼ阻害剤
US8822689B2 (en) 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
CN103030575B (zh) * 2013-01-04 2014-10-01 中国农业大学 一类双氰基酰胺化合物及其合成方法与应用
AR094961A1 (es) 2013-03-15 2015-09-09 Lilly Co Eli 1-hidroxi-benzooxaboroles como agentes antiparasitarios
AU2014286221B2 (en) * 2013-07-01 2018-05-31 The University Of Melbourne N-(1-cyano-2-hydroxy-1-methyl-ethyl)-4-(trifluoromethylsulfanyl)benzamide derivatives for use as nematocidal drugs
EP2821412A1 (en) * 2013-07-01 2015-01-07 Universität Zürich Organometallic 2-cyano-2-aminobenzoate-propyl derivates and their use as anthelmintics
AU2014319290B2 (en) 2013-09-13 2019-07-18 Pitney Pharmaceuticals Pty Limited Anticancer agent comprising aminoacetonitrile compound as active ingredient
WO2015044396A1 (en) 2013-09-26 2015-04-02 Universität Zürich Bis-organometallic 2-amino-3-hydroxy-2-methylpropanenitrile derivatives for use as anthelmintics
MX2016003799A (es) * 2013-09-26 2016-10-05 Univ Zuerich Compuestos organometalicos para usar como antihelminticos.
AU2014326683A1 (en) * 2013-09-26 2016-03-24 The University Of Melbourne Organometallic N-2-cyano-1-hydroxypropan-2-yl for use as anthelmintics
EP3062790B1 (en) * 2013-11-01 2023-03-08 Pitney Pharmaceuticals Pty Limited Pharmaceutical combinations for the treatment of cancer
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
WO2021177334A1 (ja) * 2020-03-04 2021-09-10 国立大学法人山口大学 新規なフルオロアルカン誘導体及びそれらを用いたゲル化剤

Family Cites Families (24)

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FR1441499A (fr) * 1964-02-14 1966-06-10 Geigy Ag J R Nouveaux esters phényliques doués de propriétés antimicrobiennes, utilisables en particulier pour la protection des matériaux organiques
US4515731A (en) * 1975-08-25 1985-05-07 Monsanto Company Asymmetric catalysis
US6239077B1 (en) * 1998-05-01 2001-05-29 Nihon Nohyaku Co., Ltd. Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof
EP1392281B1 (en) * 2000-12-20 2007-02-21 Novartis AG Anti-endoparasitic amidoacetonitrils
AR035531A1 (es) * 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
DE60217099T2 (de) * 2001-05-15 2007-08-09 Novartis Ag Benzamidoacetonitrilderivate und ihre verwendung als antiparasitika
AR036054A1 (es) * 2001-06-15 2004-08-04 Novartis Ag Uso de compuestos de aminoacetonitrilo para el control de plagas, una composicion y un proceso para dicho control y una composicion farmaceutica contra parasitos
WO2003004474A1 (en) 2001-07-06 2003-01-16 Syngenta Participations Ag Pesticidally active aminoacetonitriles
WO2003031394A1 (en) * 2001-10-04 2003-04-17 Novartig Ag Organic compounds
US7262209B2 (en) * 2001-10-04 2007-08-28 Novartis Animal Health Us, Inc. Carbonyloxy-cyanomethyl compounds as antiparasitic agents
TW200300140A (en) * 2001-11-14 2003-05-16 Novartis Ag Organic compounds
AR037746A1 (es) * 2001-12-06 2004-12-01 Novartis Ag Compuestos derivados de amidoacetonitrilo, un procedimiento para su preparacion, un procedimiento para la preparacion de compuestos intermediarios, una composicion para combatir parasitos, un procedimiento para combatir dichos parasitos, y el empleo de dichos derivados para la preparacion de una com
AR038156A1 (es) * 2002-01-21 2004-12-29 Novartis Ag Compuestos de amidoacetonitrilo, proceso para su preparacion, composicion para controlar los parasitos, y uso de estos compuestos para preparar una composicion farmaceutica
TW200400931A (en) * 2002-05-22 2004-01-16 Novartis Ag Organic compounds
TW200400004A (en) 2002-05-22 2004-01-01 Novartis Ag Organic compounds
AR039961A1 (es) * 2002-06-06 2005-03-09 Novartis Ag Derivados de amidoacetonitrilo y su uso como pesticida
AR040149A1 (es) * 2002-06-07 2005-03-16 Novartis Ag Compuestos de aminoacetonitrilo, un proceso para su preparacion, composicion, y uso del compuesto
TW200400932A (en) * 2002-06-19 2004-01-16 Novartis Ag Organic compounds
GB0214117D0 (en) * 2002-06-19 2002-07-31 Syngenta Participations Ag N-sulphonylaminoacetonitriles having pesticidal properties
AR042420A1 (es) * 2002-09-11 2005-06-22 Novartis Ag Benzotriazolil- aminoacetonitril compuestos, proceso para su preparacion, metodo y uso de los mismos en el control de endo- y ecto-parasitos dentro y sobre ganado productor de sangre caliente y animales domesticos y plantas, y en la preparacion de una composicion farmaceutica
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
AR046757A1 (es) * 2003-12-10 2005-12-21 Novartis Ag Amidoacetonitrilos utiles como pesticidas
AR049391A1 (es) * 2004-06-10 2006-07-26 Novartis Ag Derivados de aminoacetonitrilo y su uso para controlar parasitos en animales de sangre caliente
EP1812385B1 (en) 2004-11-09 2012-07-18 Novartis AG Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates

Also Published As

Publication number Publication date
KR20060088122A (ko) 2006-08-03
CA2544741A1 (en) 2005-05-19
KR100793462B1 (ko) 2008-01-14
DK1682493T3 (da) 2009-04-20
TW200528024A (en) 2005-09-01
JP4319680B2 (ja) 2009-08-26
SI1682493T1 (sl) 2009-06-30
NZ546830A (en) 2009-07-31
GB0402677D0 (en) 2004-03-10
BRPI0416294B1 (pt) 2018-06-05
RU2006119506A (ru) 2007-12-27
EP1682493A1 (en) 2006-07-26
ES2317070T3 (es) 2009-04-16
AR046322A1 (es) 2005-11-30
CN100447130C (zh) 2008-12-31
AU2004287611B2 (en) 2008-05-15
US7494956B2 (en) 2009-02-24
CN1902162A (zh) 2007-01-24
DE602004018967D1 (de) 2009-02-26
US7964635B2 (en) 2011-06-21
JP2007510632A (ja) 2007-04-26
PL1682493T3 (pl) 2009-06-30
MXPA06005036A (es) 2006-07-06
CA2544741C (en) 2012-08-07
ATE420066T1 (de) 2009-01-15
US20070072944A1 (en) 2007-03-29
BRPI0416294A (pt) 2007-01-23
TWI342875B (en) 2011-06-01
AU2004287611A1 (en) 2005-05-19
WO2005044784A1 (en) 2005-05-19
RU2370485C2 (ru) 2009-10-20
EP1682493B1 (en) 2009-01-07
EP1682493B8 (en) 2009-11-25
US20090176868A1 (en) 2009-07-09

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