[go: up one dir, main page]

PT1525193E - Acylaminothiazole derivatives, preparation and therapeutic use thereof - Google Patents

Acylaminothiazole derivatives, preparation and therapeutic use thereof Download PDF

Info

Publication number
PT1525193E
PT1525193E PT03750801T PT03750801T PT1525193E PT 1525193 E PT1525193 E PT 1525193E PT 03750801 T PT03750801 T PT 03750801T PT 03750801 T PT03750801 T PT 03750801T PT 1525193 E PT1525193 E PT 1525193E
Authority
PT
Portugal
Prior art keywords
preparation
therapeutic use
acylaminothiazole derivatives
acylaminothiazole
derivatives
Prior art date
Application number
PT03750801T
Other languages
Portuguese (pt)
Inventor
Viviane Van Dorsselaer
Bruno Schoentjes
Sylvie Baltzer
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of PT1525193E publication Critical patent/PT1525193E/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT03750801T 2002-07-17 2003-07-11 Acylaminothiazole derivatives, preparation and therapeutic use thereof PT1525193E (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0209061A FR2842523A1 (en) 2002-07-17 2002-07-17 ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (1)

Publication Number Publication Date
PT1525193E true PT1525193E (en) 2008-02-25

Family

ID=29797510

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03750801T PT1525193E (en) 2002-07-17 2003-07-11 Acylaminothiazole derivatives, preparation and therapeutic use thereof

Country Status (14)

Country Link
US (2) US7291636B2 (en)
EP (1) EP1525193B1 (en)
JP (1) JP4680593B2 (en)
AR (1) AR040570A1 (en)
AT (1) ATE382040T1 (en)
AU (1) AU2003269018A1 (en)
CY (1) CY1107903T1 (en)
DE (1) DE60318317T2 (en)
DK (1) DK1525193T3 (en)
ES (1) ES2297198T3 (en)
FR (1) FR2842523A1 (en)
PT (1) PT1525193E (en)
TW (1) TWI313680B (en)
WO (1) WO2004009565A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2842523A1 (en) * 2002-07-17 2004-01-23 Sanofi Synthelabo ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
BR0314611A (en) * 2002-10-09 2005-07-26 Pfizer Prod Inc Thiazole compounds for the treatment of neurodegenerative disorders
EP1700856B1 (en) * 2003-12-26 2015-11-11 Kyowa Hakko Kirin Co., Ltd. Thiazole derivative
WO2005073226A1 (en) * 2004-01-16 2005-08-11 Sanofi-Aventis Acylaminothiazole derivatives, preparation method thereof and use of same in therapeutics
DK1709018T3 (en) * 2004-01-16 2011-11-14 Sanofi Sa Acylaminothiazole derivatives and their use as beta-amyloid inhibitors
FR2865206B1 (en) * 2004-01-16 2009-02-06 Sanofi Synthelabo ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2873370B1 (en) * 2004-07-22 2006-10-20 Sanofi Synthelabo ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
US7384968B2 (en) * 2004-04-01 2008-06-10 Pfizer Inc. Thiazole-amine compounds for the treatment of neurodegenerative disorders
US20050222227A1 (en) * 2004-04-01 2005-10-06 Pfizer Inc Oxazole-amine compounds for the treatment of neurodegenerative disorders
ATE399758T1 (en) * 2004-08-03 2008-07-15 Chiesi Farma Spa DERIVATIVES OF 1-PHENYLALKANECARBONIC ACIDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
EP1981884B1 (en) * 2006-01-18 2012-06-13 Amgen, Inc Thiazole compounds as protein kinase b (pkb) inhibitors
WO2007116901A1 (en) * 2006-04-05 2007-10-18 Banyu Pharmaceutical Co., Ltd. Novel arylamide derivative
CN100415709C (en) * 2006-05-15 2008-09-03 西北大学 β-(3,4-Dihydroxyphenyl)-α-hydroxybornyl propionate, its synthesis method and use
DE102006048042A1 (en) * 2006-10-11 2008-04-17 Bayer Healthcare Ag Acylaminoimidazoles and acylaminothiazoles
JP2010533715A (en) 2007-07-17 2010-10-28 アムジエン・インコーポレーテツド Heterocyclic PKB regulator
US7919504B2 (en) * 2007-07-17 2011-04-05 Amgen Inc. Thiadiazole modulators of PKB
CN102164896A (en) * 2008-10-14 2011-08-24 埃科特莱茵药品有限公司 Phenethylamide derivatives and their heterocyclic analogues

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3796800A (en) * 1971-11-22 1974-03-12 Uniroyal Inc Anti-inflammatory triazole compositions and methods for using same
FR2546520B1 (en) * 1983-05-27 1985-08-30 Sanofi Sa NOVEL ANTIBIOTIC COMPOUNDS DERIVED FROM CEPHALOSPORINS
US5712270A (en) * 1995-11-06 1998-01-27 American Home Products Corporation 2-arylamidothiazole derivatives with CNS activity
CN1237960A (en) * 1996-11-22 1999-12-08 伊兰药品公司 N (aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and method for inhibiting 'beta'-amyloid peptide release and/or its synthesis by use of such compounds
FR2842523A1 (en) * 2002-07-17 2004-01-23 Sanofi Synthelabo ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
BR0314611A (en) * 2002-10-09 2005-07-26 Pfizer Prod Inc Thiazole compounds for the treatment of neurodegenerative disorders

Also Published As

Publication number Publication date
JP2005538086A (en) 2005-12-15
WO2004009565A2 (en) 2004-01-29
TW200413341A (en) 2004-08-01
JP4680593B2 (en) 2011-05-11
DE60318317T2 (en) 2009-07-09
ATE382040T1 (en) 2008-01-15
AU2003269018A1 (en) 2004-02-09
CY1107903T1 (en) 2013-09-04
US7795289B2 (en) 2010-09-14
FR2842523A1 (en) 2004-01-23
US20050182104A1 (en) 2005-08-18
DE60318317D1 (en) 2008-02-07
US7291636B2 (en) 2007-11-06
TWI313680B (en) 2009-08-21
AR040570A1 (en) 2005-04-13
US20080051436A1 (en) 2008-02-28
EP1525193B1 (en) 2007-12-26
EP1525193A2 (en) 2005-04-27
ES2297198T3 (en) 2008-05-01
WO2004009565A3 (en) 2004-04-08
DK1525193T3 (en) 2008-04-28

Similar Documents

Publication Publication Date Title
IL159275A0 (en) Phenylsulfonyl-1, 3-dihydro-2h-indole-2-one derivatives, their preparation and their therapeutic use
AU2002340999A1 (en) Phenylsulfonyl-1,3-dihydro-2h-indole-2-one derivatives, their preparation and their therapeutic use
IL180284A0 (en) 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof
IL180770A0 (en) Oxopiperidine derivatives, preparation and therapeutic use thereof
HRP20041157B1 (en) Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof
IL172733A0 (en) Diphenylpyridine derivatives, preparation and therapeutic application thereof
PT1525193E (en) Acylaminothiazole derivatives, preparation and therapeutic use thereof
TWI318974B (en) Acylaminothiazole derivatives, their preparation and their therapeutic use
IL180797A0 (en) Amino-tropane derivatives, preparation thereof and therapeutic use thereof
HK1074446A1 (en) 3-phenyl substituted pyridoindolone, preparation and therapeutic use thereof
TWI320413B (en) 1,4-diazabicyclo [ 3.2.2 ] nonanecarboxamide derivatives, preparation thereof and therapeutic use thereof
IL156647A0 (en) 2-arylimino-2,3-dihydrothiazole derivatives, methods for preparing them and therapeutic use thereof
HK1074444A1 (en) Acyloxypyrrolidine derivatives, preparation and therapeutic use thereof
PL374858A1 (en) Novel arylimidazole derivatives, preparation and therapeutic uses thereof
PL365342A1 (en) Mikanolide derivatives, their preparation and therapeutic uses
HK1065792A1 (en) 3-Heteroaryl-3,5-dihydro-4-oxo-4H-pyridazino Ä4,5-BÜindole-1-carboxamide derivatives, their preparation and therapeutic use
HK1107340A1 (en) 4-arylmorpholin-3-one derivatives, preparation and therapeutic use thereof
SI1525198T1 (en) Acyloxypyrrolidine derivatives, preparation and therapeutic use thereof
SI1525193T1 (en) Acylaminothiazole derivatives, preparation and therapeutic use thereof
SI1513835T1 (en) Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof
SI1513836T1 (en) Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof
IL165420A0 (en) Piperazinylacylpiperidine derivatives their preparation and therapeutic use thereof
IL156593A0 (en) Mikanolide derivatives, their preparation and therapeutic uses
AU2002355351A1 (en) Acylaminothiazole derivatives, their preparation and therapeutic use