PT1525193E - Acylaminothiazole derivatives, preparation and therapeutic use thereof - Google Patents
Acylaminothiazole derivatives, preparation and therapeutic use thereof Download PDFInfo
- Publication number
- PT1525193E PT1525193E PT03750801T PT03750801T PT1525193E PT 1525193 E PT1525193 E PT 1525193E PT 03750801 T PT03750801 T PT 03750801T PT 03750801 T PT03750801 T PT 03750801T PT 1525193 E PT1525193 E PT 1525193E
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- therapeutic use
- acylaminothiazole derivatives
- acylaminothiazole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0209061A FR2842523A1 (en) | 2002-07-17 | 2002-07-17 | ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1525193E true PT1525193E (en) | 2008-02-25 |
Family
ID=29797510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT03750801T PT1525193E (en) | 2002-07-17 | 2003-07-11 | Acylaminothiazole derivatives, preparation and therapeutic use thereof |
Country Status (14)
Country | Link |
---|---|
US (2) | US7291636B2 (en) |
EP (1) | EP1525193B1 (en) |
JP (1) | JP4680593B2 (en) |
AR (1) | AR040570A1 (en) |
AT (1) | ATE382040T1 (en) |
AU (1) | AU2003269018A1 (en) |
CY (1) | CY1107903T1 (en) |
DE (1) | DE60318317T2 (en) |
DK (1) | DK1525193T3 (en) |
ES (1) | ES2297198T3 (en) |
FR (1) | FR2842523A1 (en) |
PT (1) | PT1525193E (en) |
TW (1) | TWI313680B (en) |
WO (1) | WO2004009565A2 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2842523A1 (en) * | 2002-07-17 | 2004-01-23 | Sanofi Synthelabo | ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
BR0314611A (en) * | 2002-10-09 | 2005-07-26 | Pfizer Prod Inc | Thiazole compounds for the treatment of neurodegenerative disorders |
EP1700856B1 (en) * | 2003-12-26 | 2015-11-11 | Kyowa Hakko Kirin Co., Ltd. | Thiazole derivative |
WO2005073226A1 (en) * | 2004-01-16 | 2005-08-11 | Sanofi-Aventis | Acylaminothiazole derivatives, preparation method thereof and use of same in therapeutics |
DK1709018T3 (en) * | 2004-01-16 | 2011-11-14 | Sanofi Sa | Acylaminothiazole derivatives and their use as beta-amyloid inhibitors |
FR2865206B1 (en) * | 2004-01-16 | 2009-02-06 | Sanofi Synthelabo | ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
FR2873370B1 (en) * | 2004-07-22 | 2006-10-20 | Sanofi Synthelabo | ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
US7384968B2 (en) * | 2004-04-01 | 2008-06-10 | Pfizer Inc. | Thiazole-amine compounds for the treatment of neurodegenerative disorders |
US20050222227A1 (en) * | 2004-04-01 | 2005-10-06 | Pfizer Inc | Oxazole-amine compounds for the treatment of neurodegenerative disorders |
ATE399758T1 (en) * | 2004-08-03 | 2008-07-15 | Chiesi Farma Spa | DERIVATIVES OF 1-PHENYLALKANECARBONIC ACIDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES |
EP1981884B1 (en) * | 2006-01-18 | 2012-06-13 | Amgen, Inc | Thiazole compounds as protein kinase b (pkb) inhibitors |
WO2007116901A1 (en) * | 2006-04-05 | 2007-10-18 | Banyu Pharmaceutical Co., Ltd. | Novel arylamide derivative |
CN100415709C (en) * | 2006-05-15 | 2008-09-03 | 西北大学 | β-(3,4-Dihydroxyphenyl)-α-hydroxybornyl propionate, its synthesis method and use |
DE102006048042A1 (en) * | 2006-10-11 | 2008-04-17 | Bayer Healthcare Ag | Acylaminoimidazoles and acylaminothiazoles |
JP2010533715A (en) | 2007-07-17 | 2010-10-28 | アムジエン・インコーポレーテツド | Heterocyclic PKB regulator |
US7919504B2 (en) * | 2007-07-17 | 2011-04-05 | Amgen Inc. | Thiadiazole modulators of PKB |
CN102164896A (en) * | 2008-10-14 | 2011-08-24 | 埃科特莱茵药品有限公司 | Phenethylamide derivatives and their heterocyclic analogues |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3796800A (en) * | 1971-11-22 | 1974-03-12 | Uniroyal Inc | Anti-inflammatory triazole compositions and methods for using same |
FR2546520B1 (en) * | 1983-05-27 | 1985-08-30 | Sanofi Sa | NOVEL ANTIBIOTIC COMPOUNDS DERIVED FROM CEPHALOSPORINS |
US5712270A (en) * | 1995-11-06 | 1998-01-27 | American Home Products Corporation | 2-arylamidothiazole derivatives with CNS activity |
CN1237960A (en) * | 1996-11-22 | 1999-12-08 | 伊兰药品公司 | N (aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and method for inhibiting 'beta'-amyloid peptide release and/or its synthesis by use of such compounds |
FR2842523A1 (en) * | 2002-07-17 | 2004-01-23 | Sanofi Synthelabo | ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
BR0314611A (en) * | 2002-10-09 | 2005-07-26 | Pfizer Prod Inc | Thiazole compounds for the treatment of neurodegenerative disorders |
-
2002
- 2002-07-17 FR FR0209061A patent/FR2842523A1/en active Pending
-
2003
- 2003-07-11 DE DE60318317T patent/DE60318317T2/en not_active Expired - Lifetime
- 2003-07-11 PT PT03750801T patent/PT1525193E/en unknown
- 2003-07-11 DK DK03750801T patent/DK1525193T3/en active
- 2003-07-11 AT AT03750801T patent/ATE382040T1/en active
- 2003-07-11 EP EP03750801A patent/EP1525193B1/en not_active Expired - Lifetime
- 2003-07-11 JP JP2004522233A patent/JP4680593B2/en not_active Expired - Fee Related
- 2003-07-11 WO PCT/FR2003/002194 patent/WO2004009565A2/en active IP Right Grant
- 2003-07-11 ES ES03750801T patent/ES2297198T3/en not_active Expired - Lifetime
- 2003-07-11 AU AU2003269018A patent/AU2003269018A1/en not_active Abandoned
- 2003-07-15 AR AR20030102538A patent/AR040570A1/en unknown
- 2003-07-16 TW TW092119408A patent/TWI313680B/en not_active IP Right Cessation
-
2005
- 2005-01-14 US US11/035,803 patent/US7291636B2/en not_active Expired - Fee Related
-
2007
- 2007-09-21 US US11/859,443 patent/US7795289B2/en not_active Expired - Fee Related
-
2008
- 2008-03-07 CY CY20081100273T patent/CY1107903T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2005538086A (en) | 2005-12-15 |
WO2004009565A2 (en) | 2004-01-29 |
TW200413341A (en) | 2004-08-01 |
JP4680593B2 (en) | 2011-05-11 |
DE60318317T2 (en) | 2009-07-09 |
ATE382040T1 (en) | 2008-01-15 |
AU2003269018A1 (en) | 2004-02-09 |
CY1107903T1 (en) | 2013-09-04 |
US7795289B2 (en) | 2010-09-14 |
FR2842523A1 (en) | 2004-01-23 |
US20050182104A1 (en) | 2005-08-18 |
DE60318317D1 (en) | 2008-02-07 |
US7291636B2 (en) | 2007-11-06 |
TWI313680B (en) | 2009-08-21 |
AR040570A1 (en) | 2005-04-13 |
US20080051436A1 (en) | 2008-02-28 |
EP1525193B1 (en) | 2007-12-26 |
EP1525193A2 (en) | 2005-04-27 |
ES2297198T3 (en) | 2008-05-01 |
WO2004009565A3 (en) | 2004-04-08 |
DK1525193T3 (en) | 2008-04-28 |
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