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PT1210349E - Pirazolo-¬4,3-d|-pirimidinas - Google Patents

Pirazolo-¬4,3-d|-pirimidinas

Info

Publication number
PT1210349E
PT1210349E PT00960511T PT00960511T PT1210349E PT 1210349 E PT1210349 E PT 1210349E PT 00960511 T PT00960511 T PT 00960511T PT 00960511 T PT00960511 T PT 00960511T PT 1210349 E PT1210349 E PT 1210349E
Authority
PT
Portugal
Prior art keywords
pyrazolo
pyrimidines
Prior art date
Application number
PT00960511T
Other languages
English (en)
Inventor
Schelling Dr Pierre
Rochus Jonas
Maria Christadler
Hans-Michael Eggenweiler
Norbert Beier
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PT1210349E publication Critical patent/PT1210349E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT00960511T 1999-09-06 2000-08-24 Pirazolo-¬4,3-d|-pirimidinas PT1210349E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19942474A DE19942474A1 (de) 1999-09-06 1999-09-06 Pyrazolo[4,3-d]pyrimidine

Publications (1)

Publication Number Publication Date
PT1210349E true PT1210349E (pt) 2003-06-30

Family

ID=7920966

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00960511T PT1210349E (pt) 1999-09-06 2000-08-24 Pirazolo-¬4,3-d|-pirimidinas

Country Status (23)

Country Link
US (1) US6777419B1 (pt)
EP (1) EP1210349B1 (pt)
JP (1) JP4975921B2 (pt)
KR (1) KR20020025253A (pt)
CN (1) CN1145627C (pt)
AR (1) AR025569A1 (pt)
AT (1) ATE231866T1 (pt)
AU (1) AU773878B2 (pt)
BR (1) BR0013781A (pt)
CA (1) CA2384037C (pt)
CZ (1) CZ294587B6 (pt)
DE (2) DE19942474A1 (pt)
DK (1) DK1210349T3 (pt)
ES (1) ES2189766T3 (pt)
HU (1) HUP0202624A3 (pt)
MX (1) MXPA02002383A (pt)
NO (1) NO20021083L (pt)
PL (1) PL353366A1 (pt)
PT (1) PT1210349E (pt)
RU (1) RU2249594C2 (pt)
SK (1) SK3132002A3 (pt)
WO (1) WO2001018004A2 (pt)
ZA (1) ZA200202653B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10031584A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
DE10058662A1 (de) * 2000-11-25 2002-05-29 Merck Patent Gmbh Verwendung von Pyrazolo[4,3-d]pyrimidinen
AU2002229573A1 (en) * 2000-12-19 2002-07-01 Merck Patent Gmbh Pharmaceutical formulation containing pyrazolo(4,3-D)pyrimidines and antithrombotic agents, calcium-antagonists, prostaglandins or prostaglandin derivatives
DE10103647A1 (de) 2001-01-27 2002-08-01 Merck Patent Gmbh Verfahren zur Herstellung eines Pyrazolo (4,3-d) pyrimidinderivates
DE10148883A1 (de) * 2001-10-04 2003-04-10 Merck Patent Gmbh Pyrimidinderivate
MXPA05011643A (es) 2003-04-29 2005-12-15 Pfizer Ltd 5,7-diaminopirazolo[4,3-d]pirimidinas en el tratamiento de hipertension.
US7572799B2 (en) * 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
GB0327323D0 (en) * 2003-11-24 2003-12-31 Pfizer Ltd Novel pharmaceuticals
JP2007532526A (ja) * 2004-04-07 2007-11-15 ファイザー・インク ピラゾロ［４，３−ｄ］ピリミジン類
EA012577B1 (ru) 2005-05-12 2009-10-30 Пфайзер Инк. БЕЗВОДНЫЕ КРИСТАЛЛИЧЕСКИЕ ФОРМЫ N-[1-(2-ЭТОКСИЭТИЛ)-5-(N-ЭТИЛ-N-МЕТИЛАМИНО)-7-(4-МЕТИЛПИРИДИН-2-ИЛАМИНО)-1Н-ПИРАЗОЛО[4,3-d]ПИРИМИДИН-3-КАРБОНИЛ]МЕТАНСУЛЬФОНАМИДА
NL2000291C2 (nl) 2005-11-10 2009-02-17 Pfizer Prod Inc 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H- pyrazool(4,3-d)pyrimidine-5-yl)piperidine-4-carbonzuur en zouten daarvan.
TWI606049B (zh) * 2011-04-21 2017-11-21 原真股份有限公司 新穎激酶抑制劑
CZ308056B6 (cs) * 2015-07-20 2019-11-27 Ustav Experimentalni Botaniky Av Cr V V I 5-Substituované-7-[4-(substituované)benzyl]amino-3-isopropylpyrazolo[4,3-d]pyrimidiny, jejich použití jako antirevmatika, a farmaceutické přípravky
US10034861B2 (en) 2016-07-04 2018-07-31 H. Lundbeck A/S 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors
AR113926A1 (es) 2017-12-14 2020-07-01 H Lundbeck As Derivados de 1h-pirazolo[4,3-b]piridinas
US11634416B2 (en) * 2017-12-14 2023-04-25 H. Lundbeck A/S Combination treatments comprising administration of 1H-pyrazolo[4,3-b]pyridines
CN111511742B (zh) 2017-12-20 2023-10-27 H.隆德贝克有限公司 作为PDE1抑制剂的吡唑并[4,3-b]吡啶和咪唑并[1,5-a]嘧啶
US10766893B2 (en) * 2017-12-20 2020-09-08 H. Lundbeck A/S 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256650A (en) * 1989-03-29 1993-10-26 Merrell Dow Pharmaceuticals Inc. Selective adenosine receptor agents
DE19644228A1 (de) * 1996-10-24 1998-04-30 Merck Patent Gmbh Thienopyrimidine
NZ338075A (en) * 1997-04-25 2000-10-27 Pfizer Ltd Pyrazolopyrimidinones which inhibit type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterase (cGMP PED5) for the treatment of sexual dysfunction
DE19752952A1 (de) * 1997-11-28 1999-06-02 Merck Patent Gmbh Thienopyrimidine
DE10031584A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
DE10058662A1 (de) * 2000-11-25 2002-05-29 Merck Patent Gmbh Verwendung von Pyrazolo[4,3-d]pyrimidinen
DE10060388A1 (de) * 2000-12-05 2002-06-06 Merck Patent Gmbh Verwendung von Pyrazolo [4,3-d]pyrimidinen
DE10103647A1 (de) * 2001-01-27 2002-08-01 Merck Patent Gmbh Verfahren zur Herstellung eines Pyrazolo (4,3-d) pyrimidinderivates

Also Published As

Publication number Publication date
PL353366A1 (en) 2003-11-17
DE19942474A1 (de) 2001-03-15
HUP0202624A3 (en) 2004-11-29
ES2189766T3 (es) 2003-07-16
CN1145627C (zh) 2004-04-14
CN1377357A (zh) 2002-10-30
DE50001191D1 (de) 2003-03-06
MXPA02002383A (es) 2002-09-02
RU2249594C2 (ru) 2005-04-10
ATE231866T1 (de) 2003-02-15
CZ294587B6 (cs) 2005-02-16
DK1210349T3 (da) 2003-05-19
WO2001018004A2 (de) 2001-03-15
CA2384037C (en) 2009-10-13
ZA200202653B (en) 2003-09-23
SK3132002A3 (en) 2002-07-02
US6777419B1 (en) 2004-08-17
HUP0202624A2 (hu) 2002-12-28
NO20021083D0 (no) 2002-03-05
AU773878B2 (en) 2004-06-10
EP1210349A2 (de) 2002-06-05
CA2384037A1 (en) 2001-03-15
CZ2002736A3 (cs) 2002-05-15
AR025569A1 (es) 2002-12-04
NO20021083L (no) 2002-03-05
JP4975921B2 (ja) 2012-07-11
AU7279300A (en) 2001-04-10
BR0013781A (pt) 2002-05-14
KR20020025253A (ko) 2002-04-03
WO2001018004A3 (de) 2001-08-09
EP1210349B1 (de) 2003-01-29
JP2003508534A (ja) 2003-03-04

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