PT1173435E - Polimorfo de 5-¬4-¬2-(n-metil-n-(2-piridil)-amino)-etoxi|benzil|tiazolidino-2,4-diona sal de acido maleico - Google Patents

Polimorfo de 5-¬4-¬2-(n-metil-n-(2-piridil)-amino)-etoxi|benzil|tiazolidino-2,4-diona sal de acido maleico

Info

Publication number: PT1173435E
Authority: PT; Portugal
Prior art keywords: diona; thiazolidine; pyridyl; benzyl; ethyl
Prior art date: 1999-04-23

Application number

PT00920892T

Other languages

English (en)

Inventor

Robert Gordon Giles

Paul David James Blackler

Christine Marie Browne

Timothy G Coakley

Gillian Morrissey

Original Assignee

Smithkline Beecham Cork Ltd

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-23

Filing date

2000-04-19

Publication date

2003-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26315461&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1173435(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-04-23 Priority claimed from GBGB9909473.2A external-priority patent/GB9909473D0/en

1999-05-25 Priority claimed from GBGB9912196.4A external-priority patent/GB9912196D0/en

2000-04-19 Application filed by Smithkline Beecham Cork Ltd, Smithkline Beecham Plc filed Critical Smithkline Beecham Cork Ltd

2003-12-31 Publication of PT1173435E publication Critical patent/PT1173435E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PT00920892T 1999-04-23 2000-04-19 Polimorfo de 5-¬4-¬2-(n-metil-n-(2-piridil)-amino)-etoxi|benzil|tiazolidino-2,4-diona sal de acido maleico PT1173435E (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9909473.2A GB9909473D0 (en)	1999-04-23	1999-04-23	Novel compounds
GBGB9912196.4A GB9912196D0 (en)	1999-05-25	1999-05-25	Novel pharmaceutical

Publications (1)

Publication Number	Publication Date
PT1173435E true PT1173435E (pt)	2003-12-31

Family

ID=26315461

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT00920892T PT1173435E (pt)	1999-04-23	2000-04-19	Polimorfo de 5-¬4-¬2-(n-metil-n-(2-piridil)-amino)-etoxi\|benzil\|tiazolidino-2,4-diona sal de acido maleico

Country Status (40)

Country	Link
US (2)	US6806280B1 (pt)
EP (2)	EP1173435B1 (pt)
JP (1)	JP2002543077A (pt)
KR (1)	KR100744360B1 (pt)
CN (1)	CN1167702C (pt)
AP (1)	AP1598A (pt)
AR (2)	AR023561A1 (pt)
AT (1)	ATE246191T1 (pt)
AU (1)	AU765005B2 (pt)
BG (1)	BG65485B1 (pt)
BR (1)	BR0009932A (pt)
CA (1)	CA2370280A1 (pt)
CO (1)	CO5170421A1 (pt)
CZ (1)	CZ20013800A3 (pt)
DE (1)	DE60004196T2 (pt)
DK (1)	DK1173435T3 (pt)
DZ (1)	DZ3156A1 (pt)
EA (1)	EA004541B1 (pt)
ES (1)	ES2203453T3 (pt)
HK (1)	HK1045153B (pt)
HR (1)	HRP20010772B1 (pt)
HU (1)	HUP0200931A3 (pt)
IL (1)	IL146111A0 (pt)
MA (1)	MA25356A1 (pt)
MX (1)	MXPA01010821A (pt)
MY (1)	MY131973A (pt)
NO (1)	NO320574B1 (pt)
NZ (1)	NZ515168A (pt)
OA (1)	OA11872A (pt)
PE (1)	PE20010044A1 (pt)
PL (1)	PL351684A1 (pt)
PT (1)	PT1173435E (pt)
SK (1)	SK286427B6 (pt)
TR (1)	TR200103062T2 (pt)
TW (1)	TWI283677B (pt)
UA (1)	UA67844C2 (pt)
UY (1)	UY26121A1 (pt)
WO (1)	WO2000064896A1 (pt)
YU (1)	YU75301A (pt)
ZA (1)	ZA200108719B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20020137940A1 (en)	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726568D0 (en)	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US6664278B2 (en)	1997-12-16	2003-12-16	Smithkline Beecham P.L.C.	Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
ES2204557T3 (es)	1999-04-23	2004-05-01	Smithkline Beecham Plc	Derivado de tiazolidindiona y su uso como antidiabetico.
US20040248945A1 (en)	1999-04-23	2004-12-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
ATE246191T1 (de) *	1999-04-23	2003-08-15	Smithkline Beecham Plc	Polymorph von 5-(4-(2-(n-methyl-n-(2- pyrdyl)amino)äthoxy)benzyl)thiazolidin-2,4-dion maleinsäuresalz
GB0006133D0 (en)	2000-03-14	2000-05-03	Smithkline Beecham Plc	Novel pharmaceutical
IL155036A0 (en) *	2000-09-26	2003-10-31	Reddy Research Foundation	Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl) amino] ethoxy] benzyl] thiazolidine-2,4-dione maleate and pharmaceutical compositions containing the same
US7241895B2 (en)	2000-09-26	2007-07-10	Dr. Reddy's Laboratories Limited	Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino[ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
CZ305162B6 (cs) *	2002-04-19	2015-05-27	Faes Farma, S.A.	Polymorf 1 bilastinu, způsob jeho přípravy a lékařské aplikace a farmaceutický přípravek s jeho obsahem
GB0307259D0 (en) *	2003-03-28	2003-05-07	Glaxo Group Ltd	Process
EP1468997A3 (en) *	2003-04-18	2004-11-03	CHEMI S.p.A.	Polymorphous forms of rosiglitazone maleate
GB2405403A (en) *	2003-08-29	2005-03-02	Cipla Ltd	Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
EP1709038A2 (en) *	2004-01-28	2006-10-11	Usv Limited	A process for the preparation of 5- 4- 2- n-methyl -n-(2-pyridyl) amino ethoxy phenyl methyl thiaz olidine-2, 4-dione maleate
ITMI20041537A1 (it) *	2004-07-28	2004-10-28	Chemi Spa	Nuova forma polimorfa del rosiglitazone maleato
CZ298424B6 (cs) *	2005-05-24	2007-09-26	Zentiva, A. S.	Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
US20090076093A1 (en) *	2007-09-14	2009-03-19	Protia, Llc	Deuterium-enriched rosiglitazone
EP2184055A1 (en)	2008-11-07	2010-05-12	LEK Pharmaceuticals d.d.	Process for preparing solid dosage forms of rosiglitazone maleate
JP2010013472A (ja) *	2009-09-09	2010-01-21	Faes Farma Sa	４−［２−［１−（２−エトキシエチル）−１Ｈ−ベンズイミダゾール−２−イル］−１−ピペリジニル］エチル］−α，α−ジメチルベンゼノ酢酸の多形体
MX2019007073A (es)	2016-12-16	2019-10-15	Janssen Pharmaceutica Nv	Inhibidores de moléculas pequeñas de la familia de quinasas jak.
JOP20190144A1 (ar)	2016-12-16	2019-06-16	Janssen Pharmaceutica Nv	إيميدازو بيرولو بيريدين كمثبطات لعائلة jak الخاصة بإنزيمات الكيناز
TW202016110A (zh)	2018-06-15	2020-05-01	比利時商健生藥品公司	Ｊａｋ激酶家族之小分子抑制劑

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE186724T1 (de)	1987-09-04	1999-12-15	Beecham Group Plc	Substituierte thiazolidindionderivate
GB9124513D0 (en)	1991-11-19	1992-01-08	Smithkline Beecham Plc	Novel process
US6462337B1 (en) *	2000-04-20	2002-10-08	Agilent Technologies, Inc.	Mass spectrometer electrospray ionization
GB9218830D0 (en)	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
US5741803A (en)	1992-09-05	1998-04-21	Smithkline Beecham Plc	Substituted thiazolidinedionle derivatives
US5457109A (en) *	1993-09-15	1995-10-10	Warner-Lambert Company	Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus
DE4404198A1 (de)	1994-02-10	1995-08-17	Henkel Kgaa	2-Fluor-6-nitroaniline
US6632947B2 (en) *	1997-02-18	2003-10-14	Smithkline Beecham Plc	Process for the preparation of substituted thiazolidinedione
UY24886A1 (es) *	1997-02-18	2001-08-27	Smithkline Beecham Plc	Tiazolidindiona
GB9711683D0 (en) *	1997-06-05	1997-08-06	Smithkline Beecham Plc	Composition
US7091359B2 (en) *	1997-11-04	2006-08-15	Smithkline Beecham Plc	Process for the preparation of thiazolidinedione derivatives
US20020137940A1 (en)	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726566D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US6664278B2 (en)	1997-12-16	2003-12-16	Smithkline Beecham P.L.C.	Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
GB9726563D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US6613785B2 (en) *	1998-07-21	2003-09-02	Smithkline Beecham Plc	Use of glucose uptake enhancer for reducing post-ischemic injury of the heart
DZ3164A1 (fr)	1999-04-23	2000-11-02	Smithkline Beecham Plc	Nouvel agent pharmaceutique.
ATE246191T1 (de) *	1999-04-23	2003-08-15	Smithkline Beecham Plc	Polymorph von 5-(4-(2-(n-methyl-n-(2- pyrdyl)amino)äthoxy)benzyl)thiazolidin-2,4-dion maleinsäuresalz
ES2204557T3 (es) *	1999-04-23	2004-05-01	Smithkline Beecham Plc	Derivado de tiazolidindiona y su uso como antidiabetico.
CN1277965A (zh)	2000-06-14	2000-12-27	中国医药研究开发中心	盐酸罗格列酮及其应用
IL155036A0 (en)	2000-09-26	2003-10-31	Reddy Research Foundation	Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl) amino] ethoxy] benzyl] thiazolidine-2,4-dione maleate and pharmaceutical compositions containing the same

2000
- 2000-04-19 AT AT00920892T patent/ATE246191T1/de not_active IP Right Cessation
- 2000-04-19 DE DE60004196T patent/DE60004196T2/de not_active Expired - Fee Related
- 2000-04-19 DZ DZ003156A patent/DZ3156A1/xx active
- 2000-04-19 ES ES00920892T patent/ES2203453T3/es not_active Expired - Lifetime
- 2000-04-19 JP JP2000614248A patent/JP2002543077A/ja active Pending
- 2000-04-19 EP EP00920892A patent/EP1173435B1/en not_active Expired - Lifetime
- 2000-04-19 CZ CZ20013800A patent/CZ20013800A3/cs unknown
- 2000-04-19 WO PCT/GB2000/001520 patent/WO2000064896A1/en not_active Application Discontinuation
- 2000-04-19 BR BR0009932-5A patent/BR0009932A/pt not_active Application Discontinuation
- 2000-04-19 AR ARP000101862A patent/AR023561A1/es unknown
- 2000-04-19 CN CNB008091463A patent/CN1167702C/zh not_active Expired - Fee Related
- 2000-04-19 AU AU41308/00A patent/AU765005B2/en not_active Ceased
- 2000-04-19 MX MXPA01010821A patent/MXPA01010821A/es active IP Right Grant
- 2000-04-19 EA EA200101121A patent/EA004541B1/ru not_active IP Right Cessation
- 2000-04-19 YU YU75301A patent/YU75301A/sh unknown
- 2000-04-19 AP APAP/P/2001/002330A patent/AP1598A/en active
- 2000-04-19 OA OA1200100276A patent/OA11872A/en unknown
- 2000-04-19 PL PL00351684A patent/PL351684A1/xx not_active Application Discontinuation
- 2000-04-19 PT PT00920892T patent/PT1173435E/pt unknown
- 2000-04-19 CA CA002370280A patent/CA2370280A1/en not_active Abandoned
- 2000-04-19 EP EP02080321A patent/EP1304330A3/en not_active Withdrawn
- 2000-04-19 IL IL14611100A patent/IL146111A0/xx unknown
- 2000-04-19 CO CO00028929A patent/CO5170421A1/es not_active Application Discontinuation
- 2000-04-19 HU HU0200931A patent/HUP0200931A3/hu unknown
- 2000-04-19 KR KR1020017013540A patent/KR100744360B1/ko not_active IP Right Cessation
- 2000-04-19 TR TR2001/03062T patent/TR200103062T2/xx unknown
- 2000-04-19 UA UA2001117939A patent/UA67844C2/uk unknown
- 2000-04-19 AR ARP000101867A patent/AR023565A1/es unknown
- 2000-04-19 PE PE2000000365A patent/PE20010044A1/es not_active Application Discontinuation
- 2000-04-19 DK DK00920892T patent/DK1173435T3/da active
- 2000-04-19 US US10/048,123 patent/US6806280B1/en not_active Expired - Fee Related
- 2000-04-19 SK SK1492-2001A patent/SK286427B6/sk not_active IP Right Cessation
- 2000-04-19 NZ NZ515168A patent/NZ515168A/xx unknown
- 2000-04-21 MY MYPI20001708A patent/MY131973A/en unknown
- 2000-04-24 UY UY26121A patent/UY26121A1/es not_active Application Discontinuation
- 2000-05-11 TW TW089108962A patent/TWI283677B/zh not_active IP Right Cessation
2001
- 2001-10-22 NO NO20015147A patent/NO320574B1/no unknown
- 2001-10-22 MA MA26378A patent/MA25356A1/fr unknown
- 2001-10-22 HR HR20010772A patent/HRP20010772B1/xx not_active IP Right Cessation
- 2001-10-23 ZA ZA200108719A patent/ZA200108719B/en unknown
- 2001-11-20 BG BG106121A patent/BG65485B1/bg unknown
2002
- 2002-06-28 HK HK02104879.6A patent/HK1045153B/zh not_active IP Right Cessation
2004
- 2004-09-08 US US10/935,939 patent/US20050080114A1/en not_active Abandoned

Also Published As

Publication number	Publication date
HUP0200931A3 (en)	2004-03-29
CA2370280A1 (en)	2000-11-02
OA11872A (en)	2006-03-27
TWI283677B (en)	2007-07-11
EP1173435A1 (en)	2002-01-23
HRP20010772B1 (en)	2007-05-31
BG106121A (en)	2002-05-31
MA25356A1 (fr)	2001-12-31
SK286427B6 (sk)	2008-09-05
MY131973A (en)	2007-09-28
HK1045153A1 (en)	2002-11-15
KR100744360B1 (ko)	2007-07-30
CN1167702C (zh)	2004-09-22
AU765005B2 (en)	2003-09-04
DZ3156A1 (fr)	2000-11-02
AU4130800A (en)	2000-11-10
NO320574B1 (no)	2005-12-27
US20050080114A1 (en)	2005-04-14
WO2000064896A9 (en)	2001-10-25
AR023561A1 (es)	2002-09-04
AR023565A1 (es)	2002-09-04
SK14922001A3 (sk)	2002-02-05
EA004541B1 (ru)	2004-06-24
MXPA01010821A (es)	2003-09-04
BG65485B1 (bg)	2008-09-30
IL146111A0 (en)	2002-07-25
NZ515168A (en)	2004-02-27
HUP0200931A2 (en)	2002-08-28
EP1304330A3 (en)	2003-11-19
ZA200108719B (en)	2002-06-21
HK1045153B (zh)	2004-07-09
CO5170421A1 (es)	2002-06-27
ATE246191T1 (de)	2003-08-15
DE60004196T2 (de)	2004-04-15
JP2002543077A (ja)	2002-12-17
CZ20013800A3 (cs)	2002-04-17
EP1173435B1 (en)	2003-07-30
DK1173435T3 (da)	2003-11-24
WO2000064896A1 (en)	2000-11-02
HRP20010772A2 (en)	2002-10-31
TR200103062T2 (tr)	2002-05-21
BR0009932A (pt)	2002-04-09
EA200101121A1 (ru)	2002-04-25
CN1356999A (zh)	2002-07-03
NO20015147D0 (no)	2001-10-22
US6806280B1 (en)	2004-10-19
NO20015147L (no)	2001-12-17
PL351684A1 (en)	2003-06-02
AP1598A (en)	2006-04-26
ES2203453T3 (es)	2004-04-16
YU75301A (sh)	2004-07-15
KR20010110797A (ko)	2001-12-13
UA67844C2 (uk)	2004-07-15
DE60004196D1 (de)	2003-09-04
EP1304330A2 (en)	2003-04-23
PE20010044A1 (es)	2001-03-10
AP2001002330A0 (en)	2000-12-31
UY26121A1 (es)	2000-12-29

Publication	Publication Date	Title
PT1173435E (pt)	2003-12-31	Polimorfo de 5-¬4-¬2-(n-metil-n-(2-piridil)-amino)-etoxi\|benzil\|tiazolidino-2,4-diona sal de acido maleico
NO20021988D0 (no)	2002-04-26	Overvåkningssystem for avleiringer
IT1312018B1 (it)	2002-04-04	Procedimento migliorato per la produzione di sali non igroscopicidella l(-)-carnitina.
IT1319694B1 (it)	2003-10-23	Sali di iodonio come donatori di acidi latenti.
ATE228995T1 (de)	2002-12-15	Aminomethylcarbonsäurederivate
PT1240172E (pt)	2005-02-28	Novos acidos aminopropilfosfinicos
ID28489A (id)	2001-05-31	Metode untuk membuat 4-karboksiamino-2-disubstitusi 1,2,3,4-tetrahidroquinolin
DE60007050D1 (de)	2004-01-22	IMC-Verfahren
ID28483A (id)	2001-05-31	2-(3,5-bis-trifluorometil-fenil)-metil-n-(6-morfolin-4-il-4-0-tolil-piridin-3-il)-isobutiramida
ID30091A (id)	2001-11-01	Metode untuk menyiapkan l-fenilefrina hidroklorida
EE200100708A (et)	2003-02-17	Asendatud fenoksüäädikhapped
ID27270A (id)	2001-03-22	Aparatus pemroses informasi program siaran
ATE309220T1 (de)	2005-11-15	Substituierte 1,2,3,4-tetrahydrochinolin-2- carbonsäurederivate
DE60019993D1 (de)	2005-06-16	Wässrige Lysinlösungen
ITUD990152A0 (it)	1999-08-26	Cingolo per gruppo di traino di macchine trafilatrici
PL341601A1 (en)	2001-04-23	Monoargininyl salt of (e)-3-[1-n-butyl-5-(2-(2-carboxyphenyl)methoxy-4-chlorophenyl)-1h-pyrazol-4-yl]-2-[(5-methoxy-2,3-dihydrobenzzofuran-6-yl)methyl]-2-propenic acid
ATA170799A (de)	2000-09-15	Schmiedemaschine
MA25412A1 (fr)	2002-04-01	Procede pour la preparation d'acides 2-(n-phenylamino) benzoiques.
DE10081188D2 (de)	2001-11-08	Melken
ITTO20000965A0 (it)	2000-10-16	Procedimento per produrre l'acido monocarbossilico + )-trans-crisantemico.
FR2799002B1 (fr)	2006-07-21	Procede d'imagerie laser active
AR028237A1 (es)	2003-04-30	Soluciones de acido acetilsalicilico
NO20021349D0 (no)	2002-03-19	Transformerte melkesyrebakterier
AU2001282565A1 (en)	2002-03-26	Process for preparing optically active carboxylic acid derivative
IL152681A0 (en)	2003-06-24	Process for the preparation of 4-(4-pyridinyl)benzoic acid, or a salt thereof