PT1169316E - Novos derivados do acido lipoico sua preparacao e composicoes farmaceuticas que os contem - Google Patents
Novos derivados do acido lipoico sua preparacao e composicoes farmaceuticas que os contemInfo
- Publication number
- PT1169316E PT1169316E PT00918930T PT00918930T PT1169316E PT 1169316 E PT1169316 E PT 1169316E PT 00918930 T PT00918930 T PT 00918930T PT 00918930 T PT00918930 T PT 00918930T PT 1169316 E PT1169316 E PT 1169316E
- Authority
- PT
- Portugal
- Prior art keywords
- contain
- preparation
- pharmaceutical compositions
- lipoic acid
- new derivatives
- Prior art date
Links
- AGBQKNBQESQNJD-ZETCQYMHSA-N (S)-lipoic acid Chemical class OC(=O)CCCC[C@H]1CCSS1 AGBQKNBQESQNJD-ZETCQYMHSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Anesthesiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9904132A FR2791677B1 (fr) | 1999-04-02 | 1999-04-02 | Nouveaux derives de l'acide lipoique, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
FR0002315A FR2805537A1 (fr) | 2000-02-24 | 2000-02-24 | Nouveaux derives de l'acide lipoique, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1169316E true PT1169316E (pt) | 2003-07-31 |
Family
ID=26212205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00918930T PT1169316E (pt) | 1999-04-02 | 2000-03-31 | Novos derivados do acido lipoico sua preparacao e composicoes farmaceuticas que os contem |
Country Status (20)
Country | Link |
---|---|
US (2) | US6605637B1 (pt) |
EP (1) | EP1169316B9 (pt) |
JP (1) | JP2003505341A (pt) |
KR (1) | KR100758763B1 (pt) |
CN (1) | CN1173969C (pt) |
AR (1) | AR042572A1 (pt) |
AT (1) | ATE233752T1 (pt) |
AU (1) | AU763572B2 (pt) |
CA (1) | CA2369071A1 (pt) |
DE (1) | DE60001546T9 (pt) |
DK (1) | DK1169316T3 (pt) |
ES (1) | ES2193949T3 (pt) |
HK (1) | HK1046134B (pt) |
HU (1) | HUP0200863A3 (pt) |
MY (1) | MY119231A (pt) |
NZ (1) | NZ514888A (pt) |
PL (1) | PL350994A1 (pt) |
PT (1) | PT1169316E (pt) |
TW (1) | TWI269794B (pt) |
WO (1) | WO2000059899A1 (pt) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19941217A1 (de) * | 1999-08-30 | 2001-03-15 | Asta Medica Ag | Behandlung der Migräne durch Verabreichung von alpha-Liponsäure oder Derivaten derselben |
DE60108089T2 (de) * | 2000-03-16 | 2006-03-02 | Societe De Conseils De Recherches Et D`Applications Scientifiques (S.C.R.A.S.) | Heterozyklische oder Benzol-Derivate von Liponsäure, deren Herstellung und Ederen Verwendung als Heilmittel |
IT1319196B1 (it) * | 2000-10-10 | 2003-09-26 | Laboratorio Chimico Int Spa | Sintesi dell'acido r(+)alfa-lipoico. |
WO2002044163A2 (de) | 2000-11-30 | 2002-06-06 | Basf Aktiengesellschaft | Verfahren zur herstellung von liponsäure und dihydroliponsaüre |
DE10137381A1 (de) * | 2001-07-31 | 2003-02-13 | Viatris Gmbh | Neue Modifikationen des Trometamolsalzes der R-Thioctsäure sowie Verfahren zu ihrer Herstellung |
AU2002334755B2 (en) * | 2001-09-28 | 2007-12-06 | Meagan Medical, Inc. | Method and apparatus for controlling percutaneous electrical signals |
WO2004043485A1 (fr) * | 2002-11-10 | 2004-05-27 | Institute Of Cell Biophysics Russian Academy Of Sciences | Composition presentant des proprietes antioxydantes, procede de production d'un polypeptide et methode de traitement |
US7202270B2 (en) * | 2003-06-20 | 2007-04-10 | Sami Labs Limited | Convenient stable non-hygroscopic crystalline solid forms of racemic and chiral LA-plus salts: process for their manufacture and uses |
US8916546B2 (en) | 2003-08-29 | 2014-12-23 | Therapeutic Research Llc | Materials and methods for treatment and diagnosis of disorders associated with oxidative stress |
US20070299093A1 (en) * | 2005-01-27 | 2007-12-27 | Alma Mater Studiorum-Universitá Di Bologna | Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation |
CN101146800A (zh) | 2005-01-27 | 2008-03-19 | 生物工程大学精神物质实验室 | 用于治疗阿尔茨海默病的有机化合物,它们的用途和制备方法 |
DK1754478T3 (da) | 2005-08-04 | 2009-05-04 | Encrypta Gmbh | Flydende sammensætning omfattende arginin og alfa-liponsyre og anvendelse heraf til forbedring af den seksuelle funktion |
FR2908769B1 (fr) * | 2006-11-17 | 2008-12-26 | Oreal | Nouveaux composes derives dithiolanes silicies et leur utilisation |
JP2010520333A (ja) * | 2007-03-01 | 2010-06-10 | セダーズ−シナイ メディカル センター | 〔1,2〕−ジチオラン部分を含有する抗酸化剤重合体およびその使用 |
EP2139321B1 (en) | 2007-04-18 | 2013-11-06 | Cornerstone Pharmaceuticals, Inc. | Lipoic acid derivatives |
BRPI0812729A2 (pt) | 2007-06-13 | 2019-02-12 | Pravda Jay | materiais e métodos para tratamento e diagnósticos de distúrbios associados com estresse oxidativo |
DE102007038849A1 (de) | 2007-08-16 | 2009-02-19 | Adscil Gmbh | Verwendung von R(+)-alpha-Liponsäure zur Behandlung der kryptogenen Neuropathie |
WO2009086547A1 (en) * | 2008-01-03 | 2009-07-09 | Cedars-Sinai Medical Center | Antioxidant nanosphere comprising [1,2]-dithiolane moieties |
JP2011516473A (ja) * | 2008-04-04 | 2011-05-26 | ショール,ロバート | 医薬組成物 |
WO2009148698A1 (en) | 2008-06-02 | 2009-12-10 | Cedars-Sinai Medical Center | Nanometer-sized prodrugs of nsaids |
FR2937035B1 (fr) * | 2008-10-10 | 2010-12-31 | Oreal | Composes dithiolanes ; compositions les contenant ; utilisations pour la photoprotection de la peau |
EP2350274B1 (en) | 2008-10-21 | 2019-01-23 | The General Hospital Corporation | Cell transplantation |
EP2370435B1 (en) | 2008-11-24 | 2015-01-07 | Cedars-Sinai Medical Center | Antioxidant camptothecin derivatives and antioxidant antineoplastic nanospheres thereof |
CN102395560A (zh) * | 2009-02-17 | 2012-03-28 | 因瓦斯科医疗有限公司 | 包括一氧化氮的二氢硫辛酸衍生物及其治疗应用 |
US8632512B2 (en) | 2010-04-09 | 2014-01-21 | Kci Licensing, Inc. | Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds |
EP3530741B1 (en) | 2010-08-06 | 2021-04-07 | The General Hospital Corporation D/B/A Massachusetts General Hospital | System and apparatus for cell treatment |
US8529873B2 (en) | 2011-08-24 | 2013-09-10 | Los Alamos National Security, Llc | SE-72/AS-72 generator system based on Se extraction/ As reextraction |
CA2891090A1 (en) | 2012-11-09 | 2014-05-15 | Scidose, Llc | Enema composition for treatment of ulcerative colitis having long term stability |
EP3188726B1 (en) | 2014-06-19 | 2019-08-07 | Rafael Pharmaceuticals, Inc. | Pharmaceutical compounds |
CA2965963A1 (en) | 2014-06-19 | 2015-12-23 | Robert Shorr | Lipoic acid derivatives for pharmaceutical use |
CN105949180B (zh) * | 2016-05-10 | 2018-07-10 | 中山大学 | 治疗中枢神经系统退行性疾病的化合物及其应用 |
CN106279136B (zh) * | 2016-08-15 | 2019-06-21 | 中山大学 | 治疗中枢神经系统退行性疾病或脑肿瘤的化合物及其应用 |
CN106957298B (zh) * | 2017-04-18 | 2019-07-16 | 湖南中医药大学 | 一种硫辛酸苯酚酯衍生物及其制备方法和应用 |
CN107382987A (zh) * | 2017-07-19 | 2017-11-24 | 佛山市第五人民医院 | 一种具有预防和治疗创伤性脑损伤活性的化合物及其制备方法和用途 |
EP3749697A4 (en) | 2018-02-05 | 2021-11-03 | Bio-Rad Laboratories, Inc. | CHROMATOGRAPHY RESIN WITH LIGAND MIXED MODE ANIONIC / HYDROPHOBIC EXCHANGE |
CN112999220B (zh) * | 2021-04-07 | 2022-12-13 | 中国人民解放军南部战区总医院 | α-硫辛酸在作为和/或制备金属β-内酰胺酶抑制剂中的应用 |
CN115778930B (zh) * | 2022-12-08 | 2024-02-27 | 陕西中医药大学 | 一种具有血管舒张活性的二硫缩醛类化合物在制备具有血管舒张活性药物方面的应用 |
WO2024216269A1 (en) * | 2023-04-13 | 2024-10-17 | The Regents Of The University Of California | Adjustably stable adhesive compositions for medical and non-medical uses, and recycling |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1205972B (de) | 1963-08-20 | 1965-12-02 | Merck Ag E | Verfahren zur Herstellung eines Liponsaeure-derivates |
US4938636A (en) | 1988-11-14 | 1990-07-03 | Aidlin Automation Corp. | Method and apparatus for feeding container bodies |
JPH06250330A (ja) * | 1993-03-01 | 1994-09-09 | Konica Corp | 写真フィルムの加工方法 |
CZ96798A3 (cs) * | 1997-04-02 | 1998-10-14 | Sankyo Company Limited | Deriváty dithiolanu, jejich příprava a jejich terapeutické účinky |
WO2000006550A1 (fr) * | 1998-07-31 | 2000-02-10 | Nippon Soda Co., Ltd. | Composes phenylazole, procede de production desdits composes et medicaments pour le traitement de l'hyperlipidemie |
IL142824A0 (en) * | 1998-10-26 | 2002-03-10 | Univ New York State Res Found | Lipoic acid derivatives and their use in treatment of disease |
US6369098B1 (en) * | 1999-10-05 | 2002-04-09 | Bethesda Pharmaceuticals, Inc. | Dithiolane derivatives |
US6492405B2 (en) * | 1999-12-30 | 2002-12-10 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Nitric oxide donors and pharmaceutical compositions containing them |
US6387945B2 (en) * | 2000-04-11 | 2002-05-14 | The Regents Of The University Of California | Lipoic acid analogs |
-
2000
- 2000-03-30 AR ARP000101441A patent/AR042572A1/es active IP Right Grant
- 2000-03-31 MY MYPI20001317A patent/MY119231A/en unknown
- 2000-03-31 US US09/937,823 patent/US6605637B1/en not_active Expired - Fee Related
- 2000-03-31 CA CA002369071A patent/CA2369071A1/fr not_active Abandoned
- 2000-03-31 ES ES00918930T patent/ES2193949T3/es not_active Expired - Lifetime
- 2000-03-31 CN CNB008069778A patent/CN1173969C/zh not_active Expired - Fee Related
- 2000-03-31 JP JP2000609410A patent/JP2003505341A/ja active Pending
- 2000-03-31 PT PT00918930T patent/PT1169316E/pt unknown
- 2000-03-31 AU AU39709/00A patent/AU763572B2/en not_active Ceased
- 2000-03-31 DE DE60001546T patent/DE60001546T9/de not_active Expired - Fee Related
- 2000-03-31 AT AT00918930T patent/ATE233752T1/de not_active IP Right Cessation
- 2000-03-31 PL PL00350994A patent/PL350994A1/xx unknown
- 2000-03-31 HU HU0200863A patent/HUP0200863A3/hu unknown
- 2000-03-31 WO PCT/FR2000/000814 patent/WO2000059899A1/fr active IP Right Grant
- 2000-03-31 NZ NZ514888A patent/NZ514888A/xx not_active IP Right Cessation
- 2000-03-31 EP EP00918930A patent/EP1169316B9/fr not_active Expired - Lifetime
- 2000-03-31 KR KR1020017012615A patent/KR100758763B1/ko not_active IP Right Cessation
- 2000-03-31 DK DK00918930T patent/DK1169316T3/da active
- 2000-04-01 TW TW089106172A patent/TWI269794B/zh active
-
2002
- 2002-10-10 HK HK02107396.3A patent/HK1046134B/zh not_active IP Right Cessation
-
2003
- 2003-04-21 US US10/419,671 patent/US6887891B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
HUP0200863A2 (en) | 2002-08-28 |
MY119231A (en) | 2005-04-30 |
CA2369071A1 (fr) | 2000-10-12 |
EP1169316B1 (fr) | 2003-03-05 |
CN1349523A (zh) | 2002-05-15 |
KR100758763B1 (ko) | 2007-09-14 |
HK1046134B (zh) | 2005-04-22 |
KR20010108444A (ko) | 2001-12-07 |
ATE233752T1 (de) | 2003-03-15 |
CN1173969C (zh) | 2004-11-03 |
DE60001546T2 (de) | 2004-02-19 |
EP1169316B9 (fr) | 2003-10-29 |
DE60001546T9 (de) | 2004-11-04 |
WO2000059899A8 (fr) | 2001-03-22 |
HUP0200863A3 (en) | 2005-02-28 |
PL350994A1 (en) | 2003-02-24 |
JP2003505341A (ja) | 2003-02-12 |
NZ514888A (en) | 2002-12-20 |
ES2193949T3 (es) | 2003-11-16 |
AU763572B2 (en) | 2003-07-24 |
DE60001546D1 (de) | 2003-04-10 |
AR042572A1 (es) | 2005-06-29 |
AU3970900A (en) | 2000-10-23 |
EP1169316A1 (fr) | 2002-01-09 |
US6605637B1 (en) | 2003-08-12 |
US20040019084A1 (en) | 2004-01-29 |
TWI269794B (en) | 2007-01-01 |
DK1169316T3 (da) | 2003-06-30 |
US6887891B2 (en) | 2005-05-03 |
HK1046134A1 (en) | 2002-12-27 |
WO2000059899A1 (fr) | 2000-10-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT1169316E (pt) | Novos derivados do acido lipoico sua preparacao e composicoes farmaceuticas que os contem | |
PT1202965E (pt) | Derivados de indol processos para a sua preparacao composicoes farmaceuticas que os contem e a sua aplicacao | |
PT1095932E (pt) | Derivados de acido fenoxiacetico e composicoes medicinais que os contem | |
PT1150961E (pt) | Derivados do acido pirazolecarboxilico processo para a sua preparacao e as composicoes farmaceuticas que os contem | |
PT1077692E (pt) | Preparacoes farmaceuticas estabilizadas de derivados do acido aminobutirico e processos para a sua preparacao | |
PT1042323E (pt) | Novos analogos tetraciclicos de camptotecinas processos para a sua preparacao sua utilizacao como medicamentos e composicoes farmaceuticas que os contem | |
PT1042324E (pt) | Compostos heterociclicos para inibicao da secrecaode acido gastrico processis para a sua prepara cao e suas composicoes farmaceuticas | |
PT92699A (pt) | Processo para a preparacao de novos derivados heterociclicos inibidores da enzima 5-lipoxigenase e de composicoes farmaceuticas que os contem | |
PT1572708E (pt) | Novos derivados de fluoroglicosidos heterociclicos, produtos farmaceuticos que contem estes compostos e sua utilizacao | |
EE200000725A (et) | Uued 3-arüülpropaanhappe derivaadid ja nende analoogid | |
PT876362E (pt) | Novos taxoides sua preparacao e composicoes farmaceuticas que os contem | |
PT1192122E (pt) | Derivados de benzeno processo para a sua preparacao e composicoes farmaceuticas que os contem | |
PT918759E (pt) | Novos derivados de tiazolidino-2,4-diona substituidos processos para a sua obtencao e as composicoes farmaceuticas que os contem | |
PT91287A (pt) | Processo de preparacao de derivados do acido indazol-3-carboxilico e de composicoes farmaceuticas que os contem | |
PT84319B (pt) | Processo para a preparacao de derivados substituidos de tienoimidazol e de composicoes farmaceuticas que os contem | |
PT97114A (pt) | Processo para a preparacao de derivados de hidantoina e de composicoes farmaceuticas que os contem | |
PT1049721E (pt) | Polissacaridos de sintese processo para a sua preparacao e composicoes farmaceuticas que os contem | |
PT99795A (pt) | Processo para a preparacao e novos derivados de piperidinil-benzimidazol e de composicoes farmaceuticas que os contem | |
PT89486A (pt) | Processo para a preparacao de derivados 16-de-hidro de vitamina d3 e de composicoes farmaceuticas que os contem | |
PT83558B (pt) | Processo para a preparacao de derivados da carboxamida e de composicoes farmaceuticas que os contem | |
PT1187847E (pt) | Derivados de estreptograminas sua preparacao e as composicoes que os contem | |
PT90864A (pt) | Processo para a preparacao de derivados de cromano e de composicoes farmaceuticas que os contem | |
PT1242389E (pt) | Novos derivados ramificados de 3-amino-1-fenil-h¬1,2,4|pirazole substituidos em amino processos para a sua preparacao e composicoes farmaceuticas que os contem | |
PT1118610E (pt) | Novos derivados de benzeno-sulfonamida processo para a sua preparacao e as composicoes farmaceuticas que os contem | |
PT90904A (pt) | Processo para a preparacao de derivados de 3-oxo-propanonitrilo triciclicos e de composicoes farmaceuticas que os contem |