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PT1158014E - Processo para a producao de poliesteres biodegradaveis - Google Patents

Processo para a producao de poliesteres biodegradaveis

Info

Publication number
PT1158014E
PT1158014E PT99961296T PT99961296T PT1158014E PT 1158014 E PT1158014 E PT 1158014E PT 99961296 T PT99961296 T PT 99961296T PT 99961296 T PT99961296 T PT 99961296T PT 1158014 E PT1158014 E PT 1158014E
Authority
PT
Portugal
Prior art keywords
carboxyl
polymer
omega
protected carboxyl
acid derivative
Prior art date
Application number
PT99961296T
Other languages
English (en)
Inventor
Yasutaka Igari
Hata Yoshio
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of PT1158014E publication Critical patent/PT1158014E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113Multiple emulsions, e.g. oil-in-water-in-oil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08Lactones or lactides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Biological Depolymerization Polymers (AREA)
PT99961296T 1998-12-15 1999-12-14 Processo para a producao de poliesteres biodegradaveis PT1158014E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP35649798 1998-12-15

Publications (1)

Publication Number Publication Date
PT1158014E true PT1158014E (pt) 2005-04-29

Family

ID=18449318

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99961296T PT1158014E (pt) 1998-12-15 1999-12-14 Processo para a producao de poliesteres biodegradaveis

Country Status (11)

Country Link
US (1) US6756472B1 (pt)
EP (1) EP1158014B1 (pt)
KR (1) KR100584634B1 (pt)
CN (1) CN1134479C (pt)
AT (1) ATE289205T1 (pt)
AU (1) AU1797800A (pt)
CA (1) CA2355186C (pt)
DE (1) DE69923795T2 (pt)
ES (1) ES2234325T3 (pt)
PT (1) PT1158014E (pt)
WO (1) WO2000035990A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2002114A3 (cs) 1999-07-15 2002-04-17 Takeda Chemical Industries, Ltd. Prostředek s trvalým uvolňováním, způsob jeho výroby a jeho pouľití
CA2407472A1 (en) * 2000-06-14 2002-10-23 Takeda Chemical Industries, Ltd. Sustained release compositions
KR100772950B1 (ko) 2000-08-07 2007-11-02 와꼬 쥰야꾸 고교 가부시키가이샤 젖산 중합체 및 이의 제조 방법
FR2821360B1 (fr) 2001-02-27 2003-05-30 Sod Conseils Rech Applic Procede de preparation de polyesters avec des fonctions acides libres intracatenaires
TW200526267A (en) 2001-06-29 2005-08-16 Takeda Chemical Industries Ltd Controlled release composition and method of producing the same
TWI225416B (en) * 2001-06-29 2004-12-21 Takeda Chemical Industries Ltd Sustained-release composition and process for producing the same
DE60327737D1 (de) * 2002-01-22 2009-07-09 Biomatera Inc Verfahren zur trocknung von biologisch abbaubaren polymeren
EP1923075B1 (en) * 2004-08-13 2015-11-11 Rutgers, The State University Radiopaque polymeric stents
NZ577281A (en) * 2006-12-18 2011-12-22 Takeda Pharmaceutical Sustained-release composition and method for producing the same
NZ580700A (en) * 2007-04-19 2012-01-12 Dong A Pharm Co Ltd A biodegradable microsphere composition suitable for the controlled release of glucose controlling peptide and formulation thereof
EP2508504B1 (en) * 2009-12-01 2016-04-13 Sumitomo Chemical Co., Ltd Process for preparation of cycloalkanedicarboxylic acid monoesters
CN103275312B (zh) * 2013-05-16 2015-01-21 湘潭大学 含侧羟基或侧羧基官能团的聚丙交酯及其制备方法
US20160106804A1 (en) 2014-10-15 2016-04-21 Yuhua Li Pharmaceutical composition with improved stability

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW333456B (en) * 1992-12-07 1998-06-11 Takeda Pharm Ind Co Ltd A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
CA2167920A1 (en) 1993-07-23 1995-02-02 Abraham J. Domb Nonoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
ATE178789T1 (de) 1994-02-21 1999-04-15 Takeda Chemical Industries Ltd Polyester matrix für eine pharmazeutische zusammensetzung mit verzögerter freigabe
ES2221019T3 (es) 1996-10-31 2004-12-16 Takeda Chemical Industries, Ltd. Preparacion de liberacion mantenida.
CA2316273A1 (en) * 1998-01-16 1999-07-22 Takeda Chemical Industries, Ltd. Sustained-release composition, method of its production and use thereof
CZ2002114A3 (cs) 1999-07-15 2002-04-17 Takeda Chemical Industries, Ltd. Prostředek s trvalým uvolňováním, způsob jeho výroby a jeho pouľití

Also Published As

Publication number Publication date
EP1158014A1 (en) 2001-11-28
CA2355186A1 (en) 2000-06-22
US6756472B1 (en) 2004-06-29
DE69923795D1 (de) 2005-03-24
WO2000035990A1 (fr) 2000-06-22
ES2234325T3 (es) 2005-06-16
CN1134479C (zh) 2004-01-14
ATE289205T1 (de) 2005-03-15
EP1158014B1 (en) 2005-02-16
AU1797800A (en) 2000-07-03
KR100584634B1 (ko) 2006-05-30
DE69923795T2 (de) 2006-03-16
CA2355186C (en) 2008-03-18
CN1334834A (zh) 2002-02-06
KR20010082348A (ko) 2001-08-29
EP1158014A4 (en) 2003-01-22

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