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PT106902A - ANESTHESIA CIRCUIT GAS PURIFICATION PROCESS USING MEMBRANE CONTACTORS - Google Patents

ANESTHESIA CIRCUIT GAS PURIFICATION PROCESS USING MEMBRANE CONTACTORS Download PDF

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Publication number
PT106902A
PT106902A PT106902A PT10690213A PT106902A PT 106902 A PT106902 A PT 106902A PT 106902 A PT106902 A PT 106902A PT 10690213 A PT10690213 A PT 10690213A PT 106902 A PT106902 A PT 106902A
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PT
Portugal
Prior art keywords
formula
compound
ray
present
ray diffraction
Prior art date
Application number
PT106902A
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Portuguese (pt)
Inventor
Carlos Alberto Mateus Afonso
Jo O Paulo Serejo Goul O Crespo
Luísa Alexandra Graça Neves
Isabel Maria Rôla Coelhoso
Original Assignee
Carlos Alberto Mateus Afonso
Jo O Paulo Serejo Goul O Crespo
Luísa Alexandra Graça Neves
Isabel Maria Rôla Coelhoso
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Carlos Alberto Mateus Afonso, Jo O Paulo Serejo Goul O Crespo, Luísa Alexandra Graça Neves, Isabel Maria Rôla Coelhoso filed Critical Carlos Alberto Mateus Afonso
Priority to PT106902A priority Critical patent/PT106902A/en
Priority to PCT/IB2014/060797 priority patent/WO2014170858A1/en
Publication of PT106902A publication Critical patent/PT106902A/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/104Preparation of respiratory gases or vapours specially adapted for anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/22Carbon dioxide-absorbing devices ; Other means for removing carbon dioxide
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/22Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by diffusion
    • B01D53/225Multiple stage diffusion
    • B01D53/226Multiple stage diffusion in serial connexion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/22Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by diffusion
    • B01D53/228Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by diffusion characterised by specific membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/22Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by diffusion
    • B01D53/229Integrated processes (Diffusion and at least one other process, e.g. adsorption, absorption)
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D53/00Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/22Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by diffusion
    • B01D2053/221Devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2252/00Absorbents, i.e. solvents and liquid materials for gas absorption
    • B01D2252/30Ionic liquids and zwitter-ions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2257/00Components to be removed
    • B01D2257/50Carbon oxides
    • B01D2257/504Carbon dioxide
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2259/00Type of treatment
    • B01D2259/45Gas separation or purification devices adapted for specific applications
    • B01D2259/4533Gas separation or purification devices adapted for specific applications for medical purposes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02CCAPTURE, STORAGE, SEQUESTRATION OR DISPOSAL OF GREENHOUSE GASES [GHG]
    • Y02C20/00Capture or disposal of greenhouse gases
    • Y02C20/40Capture or disposal of greenhouse gases of CO2

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Gas Separation By Absorption (AREA)

Abstract

A PRESENTE INVENÇÃO ESTÁ RELACIONADA COM A REMOÇÃO DE COMPOSTOS TÓXICOS, NOMEADAMENTE DIÓXIDO DE CARBONO, PRESENTES EM CORRENTES DE GÁS DE CIRCUITOS DE ANESTESIA. PROPÕE-SE UM PROCESSO INTEGRADO (ABSORÇÃO E REGENERAÇÃO IN-SITU) PARA A PURIFICAÇÃO DE GASES DE ANESTESIA EM CONTACTORES DE MEMBRANAS, COMBINANDO A CAPACIDADE DE LÍQUIDOS IÓNICOS OU MISTURAS EUTÉTICAS COM ESPECIFICIDADE PARA SOLUBILIZAR DIÓXIDO DE CARBONO, COM O USO DE UMA ENZIMA, ANIDRASE CARBÓNICA, QUE CATALISA A REACÇÃO DE CONVERSÃO DO CO2 EM BICARBONATO. DESTA FORMA A PRESENTE INVENÇÃO É ÚTIL, POIS ELIMINA OS PROBLEMAS DE TOXICIDADE CAUSADOS PELOS SISTEMAS ACTUAIS DE PURIFICAÇÃO DE GASES EM CIRCUITOS DE ANESTESIA; PERMITE A REGENERAÇÃO IN-SITU E À TEMPERATURA AMBIENTE DA FASE LÍQUIDA USADA PARA SOLUBILIZAÇÃO DOS GASES TÓXICOS, EVITANDO O CUSTO ASSOCIADO À ELIMINAÇÃO DE RESÍDUOS HOSPITALARES; E UTILIZA UM EQUIPAMENTO COMPACTO, CONTACTORES DE MEMBRANAS, ADEQUADO PARA UTILIZAÇÃO EM AMBIENTE HOSPITALAR.The present invention is related to the removal of toxic compounds, in particular carbon dioxide, present in gas currents of anesthesia circuits. An integrated process (In-SITU ABSORPTION AND REGENERATION) FOR THE PURIFICATION OF ANESTHESIA GASES IN MEMBRANE CONTACTORS IS COMBINED BY COMBINING THE CAPACITY OF IONIC LIQUIDS OR EUTHETIC MIXTURES WITH SPECIFICITY TO SOLUBILIZE CARBON DIOXIDE WITH THE USE OF AN ENZYME, CARBONIC ANIDRASE, WHICH CATALYSES THE CO2 CONVERSION REACTION IN BICARBONATE. In this way the present invention is useful because it eliminates the toxicity problems caused by the current systems of gas purification in anesthesia circuits; ALLOWS IN-SITU REGENERATION AND THE ENVIRONMENTAL TEMPERATURE OF THE LIQUID PHASE USED FOR SOLUBILIZATION OF TOXIC GASES, AVOIDING THE COST ASSOCIATED WITH THE DISPOSAL OF HOSPITAL RESIDUES; AND USES A COMPACT EQUIPMENT, MEMBRANE CONTACTORS, SUITABLE FOR USE IN HOSPITAL ENVIRONMENT.

Description

D E S C R I Ç A DD E S C R I E D

Proceeso de Puro :f iceção de Gases de Cireaitos do Anostesoa Mffidô Contactares do Masixrana.s*Pure Processes: Anesthesia Gaseous Phase Formation of the Anostesoa Mffidô Contact Us by Masixrana.s *

Doeiaio técnx co da xavençao A, pxeeaat.e. idgeoçiee ctie cexpeiCo * em processo òc cocoçod do ocoipo o too oóei: iras í .eexioxesiamoeito diopido de carbono ,. preaeo-tes exa cedxrsorea de gáe em ciroxxi. toe de ao.es to aio. * iuxmirio da iavençâo P e-h;pxe:ti.ve do; p.seseo.ts ln.ovo.vOo o. cari gideordis do goesoa do c 1 x cg t t o o ; d e ao e: a te e i o........o 11 X i xo n.tío oc o t a c t eras do memtvrao.sa.rn Esto ;g;sseesso; 0 ceracxxcrx. rsdo por taxar contactar orae corrente gasosa ; coa:stsoi.etd.a cor gases de a no s o s s- a a o c o e g a soe ο κ e x o eax e nexo s o e e: t oe x soo es.} s ο om oeotoctoo de meeòtra:nxo ;d , a o segurando, a oelobilixapoo e dixeo:od a doe cçrçiogtoe· geesooss tdo:0.'ias, para uno taco 1.lapida: recoptera ΠΡ gee integra, o. egsima oxex.draeo dar Pont ca. da s me xso. xxom 11 cuido idtico ou nema Tais tora estática, com ; sftaiodedo para o; dideidxe do carbono# pmrrd.tiUu!m e ode os.dxoop:oexxte remoeáo desta saae li.ceei doo 0.000 aegorido: eeooxexxtot oe mmmxo. eixos i to , e a reto.rcodacue da; tp r ;r on t e do, ;g do ele go c s t o si ,a px. ; t s f i coxia se e ;g j ei to s o b x.ebxrx’e'socdo gx }A technical theory of X-ray A, pxeeat. In the process of the invention, the reaction mixture is cooled to room temperature and the solvent is evaporated to dryness. Preliminary tests for gas in ciroxxi. toe de ao atoio * Iuxmirio of the company P e-h; pxe: ti.ve do; p.seseo.ts ln.ovo.vOo o. cari gideordis do gooa do c 1 x cg t t o o; of the memory and the memory of the memory of the memory. 0 ceracxxcrx. rsdo for charging contact gaseous stream; A preferred embodiment of the present invention relates to the use of a gas in the form of a gas in the form of a gas in the form of a gas in the form of a gas in the form of a gas in the form of a gas. : for a taco 1.lapida: recoptera ΠΡ gee integra, o. egsima oxex.draeo dar Pont ca. da s me xso. xxom 11 identical care or nema Such static, with; sftaiodedo for the; the carbon dioxide of the carbon dioxide and the removal of this carbon dioxide from about 0,000 to about 60,000 carbon dioxide. axes, and the straight line of the; tp r; r on t e of the g e s e s e s, a px. ; t s f i ave if e g i e s o b x.ebxrx'e'socdo gx}

As ρ x x. ao: x. pa o s 'Ooxx t. a g a m e s Ito i o:v ei:]. xmx:0.:p:pao ge proold;mao 'de t.oax. cagada, caies abes pa i. cs; e x. o t eias.e e. a da. le de ps o x. r .x, o ggg· o ç.e g:o s e s em t x. r co X t os cio ao;e s te a i a > .o, Begenerag-lo i 20-102 Xa a 0 teippeiõídrra aoàpiappte da isSe :: .:. ρρ,ρ: ·χ s, pipaora paiai p o a u a^ a: : raçaso a.oo gaaei' tdaaaos, c, 22icpa 0201201 to οαιροοΟφ 2caa2t.a.aX.aras da çanòprorpaa5 ap2ea22p.dp) para, 2d.P, .2i2aoçào aís aaaa.eaba hospitalar,As ρ x x. to: x. for Ooxx t. a g a m e s Ito i o: v e i:]. xmx: 0.: p: pao ge proold; mao 'de t.oax. shit, drop abes pa i. cs; and x. e.g. the da le ps or x. r .x, the ggg · o ç e g s o s in t x. The invention relates to a process for the preparation of a compound of formula (I): to afford the title compound as a white powder. ρρ, ρ: χ s, pipaora paiai poaua a:: racesaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa, ai aaaa.eaba hospital,

Antaoadam ta a da Invenção nai <roa da aaaadasaa. a. para proaonas caaapíaploo poíp cexc.a 020: "ida da oxido nltroao t%d) , 22 "d; dl ai a odlqédaa a 1--2 2 da ialdx acaaboiaetoa haXegaaadiph Apôo a 2:22001 ração ,· o dldabdo da ca.rbone {Cd:>} preseaoa na íoàatora. goaoia atingi· «a. doar da 52 ddpendi oar rèdovidb para laloras: Xnoeiloled 1,51, 10021202 paio 022222:0.1 vai a, r 00X22202.2X000 o daaae gâs a a ρ P a l a o. t a g ai) o. d a a 1 a ao. a ,Antaoadam of the Invention of the United States of America. The. for proaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa dl ai a odlqédaa a 1--2 2 da ialdx acaaboiaetoa haXegaaadiph Apóo a 2: 22001 ration, · the dldabdo of ca.rbone {Cd:>} preseaoa na íoàatora. Turkey has reached. donating from 52 per cent of the total amount of the loan to the borrower: Xnoeiloled 1.51, 10021202 paio 022222: 0.1 goes to 00X22202.2X000 the daaae gâs a a ρ P a l. t a g) i. from 1 to 2 years. The ,

iidpPiiaiidapppa ...d..:...! POOO· 2.01........1 )2)........ da:.... aprpappt o/oav 222 da 02 a p. 5- T; '51 .Ϊ. t.o:Õ ί.ΐίϊ. .;Y Yd aí i::i iY do 2 02210 d; cpppvS P a 5ro.i 2220:2 ‘pD.‘.C ' .Υ.ΐΧ:ΥΥΥΥ\;ΐΥ’·. .o 5 a O' aâlc:2,a )rPaa:?:':aap;2pa si .ap.dpi sp p a ο ago:x g ta 02 0:0 CÇ-áO COxY dpdiáii·:, 5 rd ; dll· 2 dl ...............·&gt; : ,· DÍ i CC: &lt; ? ( J a aa a s-) a-a s dr 'adi a P a a i oaoi t p 0X0 22521 ç &lt; 25 a ta -r 2220 2 cp a ) oso. paal a 22Pdida),da de oáX.pora reage íOppo o di dxi:dp&gt; da ca 0220.020· o 002222202000222 c'ai'P&gt;onp.pQ g.a' coí..2.022.0 a 0002.20« 00200:02: da aai' a apipanianda voara vrtiPirraço: aa ρ^ΙρρργρΡΡορ Pia onaátaai.p. 002 OO 0- ΡΑΧδοΟΟΟ Pa.) P.-\)P,' P a Ipraxpppps :2.20: C-5;i:C:0O PíPIOPP 010; ama olaasdo;. ; o:aoçidllidada raactlda aas apaadpea apmpaéaicop, Da 022200022222:0 PaP!aataai:c:p&gt;;p aaia ot. 11 o 22220.:00 a25o o .pppaappaappanapap: 1 x2220022120200.5 , cípípp ρρρ) ap.a.22P).2.d? aaaai).rrra.ngf. iaof Xdrapdí iiesf Xaranan oa: pirai o podar roaradr p).:ir)2;.icaaaaPd;a a dm o hidróxido- da cd.leiaç podendo fernaar aebprddptoa pp,paaif;iaXapp2rdp: rdpppaop para ο poçiaoOç.,iidpPiiaiidapppa ... d ..: ...! POOO · 2.01 ........ 1) 2) ........ da: .... aprpappt o / oav 222 da 02 a p. 5-T; .51. t.o: Õ ί.ΐίϊ. Y is from 2 022 10 d; cpppvS P a 5i 2220: 2 'pD.' C '.ΥΐΧΐΧ: ΥΥΥΥ \; ΐΥ' ·. 5a to 2a: 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to 2a to dll · 2 dl ............... · &gt; :. ? (J a aa a s-) a-a s dr 'adi a P a a o o t p 0X0 22521 ç < 25 to 20% a) bear. at 22Â ° C), the reaction temperature is 0Â ° C. of ca 0220.020 · o 002222202000222 c'ai'P> onp.pQ g'a 'coí..2.022.0 to 0002.20 «00200: 02: da aai' apipanianda voara vrtiPirraço: aa ρ ^ ΙρρργρΡΡορ Pia onaátaai.p. 002 0-ΡΑΧδοΟΟΟ Pa.) P P P a a a Ip Ip Ip Ip Ip Ip Ip Ip Ip Ip 2. 2. 2. 2. 2. 2. 2. 2. 2. 2. 2. 2. 2. 2.: 2.20: C-5; love olaasdo ;. ; Accordingly, the present invention relates to a process for the preparation of a pharmaceutical composition comprising a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a pharmaceutically acceptable excipient. 11 or 22220.:00 a25o or .pppaappaappanapap: 1 x2220022120200.5, cipípp ρρρ) ap.a.22P) .2.d? aaaai) .rrra.ngf. iaof Xdrapdí iiesf Xaranan o: p roaradr Pirai prune) .: ir) 2; .icaaaaPd, the DM of the hidróxido- cd.leiaç may fernaar aebprddptoa pp paaif; iaXapp2rdp:. rdpppaop to ο poçiaoOç,

Portar propoatar na li tara tara: algarao :aa.i opões para rd. a..i mi a ar a ooorraarra da raaí 030 3 33 i rar d á r i a a ao: t r a o .a Ota/p pmtctyt · 'pa ta O :aCdO ta : nnatear co O. p0 Ό ao.tá MX rocnPOamXt 30.3303' ti útil.1aabao Or; v'·:;' P.vÇi çad: ΟΟΟοΟ Ort.t : .. .1 Ί\..\O coopcaioáo 70-aOr da aibramido or raia ia (livra da .3 ' :io do pç tt 33 o i t b a t io ; drôa i. do dr sedar p D ,1 .17¾ cot drda' .d do de 1. ti o 0 .3 ·'' 2 s 2 de: d 00:0, a pater ; 0:0 02 ti idíp C :já / arporo a u ti 1 ia 3.0 l:vO da ron abar or verte do 2 2:?; oo·; rat la· ai; io por; d 3 l-CO a do rr xpnêr XOr hioromid 0 dr mar Oib; rito co d.idr OO: arbaoeite OO rasor ·; á'b &lt; ? Oií c:ma proa 003 3003 ;tb dada 3 '3 aor· ti .V tPmiae •ti i&gt; sol uç 03·3 men:; 0 ;13&gt; 0 OcíO i&gt; anterir nro r.o tePortar propoatar in li tare tara: algarao: aa.i options for rd. Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids Amino Acids usefull. v '· :;' The 70-aor of the arabamido or arabamido (free from 3% of the 33-carbothiocyanate hydrochloride) p D, 1 .17% cot d. of the 1, 1, 0, 3, 2, 2 of: 00: 0, pater; 0: 022 C: already / arporo au ti 1 3.0 wt.% of the rum from the 2-oxalitrile by 3: 1-COOH of the mineralogical composition: The composition of the present invention comprises the steps of: (a) preparing a compound of formula (III): (a) reacting a compound of formula (III) with a compound of formula (III): ## STR1 ## to precede nro ro

Pa r ό r am-' ao om. araromãs do abaoroãOí dato é não aa i'erdnre raçao a iano 1. t a ç a a d o aba:rdvra:ota? o ooío impiiaa a oabat àtoi aã' o do aoaorooo; :.o οηοΓίΟο aor arado o :am. a.;. r v ac;o iaa id a a to; tirdd i........aliad o.a a a.o d a r a a i ;d ao e b. aapl talo.res S:: &lt;303. λ'3.1 0.3 ii03 S 0:3.-ΐ· O 0303301. 3033o 1'. 3 O. 3 Ο Ο- 30:. t- 3 Oo 33 00/ 0 .1 O O 3 33 30000 O 3. ooo r t r ar â o dc ; :ao troo........na t a: a d apt a a a. eia a a rt aa d:a eaesf asrirp· par (deverá cornar nas. raanbrana a ap abs;:.rr vento de CCn (raa ; aspectodoar gral a. composição doo to abaoraantr dar. o nsatcriai da rmmysrara; ,· sondo,· ao ratar to# maio ama ter,· am sistema aporao de aba orça ta o arai oão r:rsarnnra a ara rrpsaeraçitò arrasa, tra Cario referido i a.oPoorr.nrberto, oc apontoo aaostooicrs ij. t .;,rr 30' &lt;303 maia fr sagaoor ro mr; .t: aa&lt;r aa.aroc arrota rn ao ri .por ti ΙαΡ.-Οο.»'·...... podopdo or..i:p.ia:.a: yr :i... ......fo .r mo pio da 00ΪΓ330 ί &lt; toa pr; toa a imo: otr ; : tb2i 30 0 enr as d- corb 1 'badra cec. 0 ab 3303 &lt;P; atr v 0 2e.aon.f por o a t.r; 0 i aor; : a corvái dor: ado 0 gá a a a .3 0 3 Ό3· oor dr dal. d sa.a ot id 3 3:θ33 sofaroco otto aao óp arar am pra dr C àtobim O d '3: afoite ' 0 s Çi rda: n ;â r loa dar p ard i d; .; iar i'.i &lt;p ia; narra O axdioaaa : rolar; 3:; a..O o oar no a perna, te orna »o t eaod a Imant. c t om cor o a a i. da la dor I. r n Para a i am di ao o ns do r a a do o a i mi dobieb t o com aaalaarr aabetânoia, ano apresentando o propienss dr rormaoao dr oomeoatss potoaoia:lrrntc tdaicor para o p&amp;c.iebte* Ho Ho.tantOj ο áxevbd.e axxadsx da oit urgia qisasxsia ao ooxaioa aaaxoss :aca.apssac caro. oxaa asa ssoabassaaa asgoesCaa ass.sss.rs;aaas.coa.t· caax xssaxtsads.s a asxa sxssxj.xaasçdo., boa xaaxa a p:rçssaaac.o oíxíxóbx:t.ass or oesb saaoa abcaassabi voa gfxcdentas para ssosaxipexxa: a xaxxioiax goasaa cie aaesdasia o, o® pesas biòsslxi.ss baaaaa, Ha uma l o ama áxiaioatá: a cosa baxax&gt; caaste,Pa r ร r r to am om. The data are not available at the time of publication. the title compound is prepared in the same manner as the product; : .o οηοΓίΟο aorado o: am. The.;. r v ac; iaa id a a to; tirdd i ........ allied to a d a r a a tio n and b. aapl talo.res S :: &lt; 303. λ'3.1 0.3 ii03 S 0: 3.-0 · 0303301. 3033 ° 1 '. 3 O. 3 Ο Ο-30 :. 3 O 3 3300/0 .1 O 3 33 30000 O 3. : by the way ........ na t a: a d apt a a a. (it will be necessary to cut the radius of the radius of the radius of the radius of the radius of the radius of the radius of the radius of the radius of the radius of the radius. in the case of rationing, he / she may have, in the form of a budget-raising system, for the purpose of destroying the shipment, the shipment referred to in the preceding paragraph, and the shipment, ; 303 maya fr sagaoor ro mr; .t: aaaaarar burp rn at ri. Por ti ΙαΡ.-Οο. »'... ...... podopdo or..i: p.ia: .a : yr: i ... ...... fo rrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrl ; Δ v 33 Ό Ό Ό 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 3: θ33 sofaroco otto the op eration of th e C atobim O d '3: f o rte d s: ; or the hearing in the leg, you will not be able to hear it. to the end of the year, the year of the year of the year of the year of the year of the year of the year. It is important to note that in the case of Oaxaca, oxaa asa ssoabassaaa asgoesCaa ass.sss.rs; aaas.coa.t · caax xssaxtsads.sa asxa sxssxj.xaasçdo., good xaaxa ap: rcssaaac.oxyxx: t.ass or oesb saaoa abcaassabi flies gfxcdentas for ssosaxipexxa: a xaxxioiax goasaa one or two weights, or both. you fell

Tra.foai.dos reoa-.atas pxxxpõeas a ssaa; da mas&gt;brao.sa para afo oossss. de Pd d &lt; saass sds a eo 1açdaa ai s:: &lt; sáiss as s aseixso l sa a· :'yai&gt; 5· &amp;. as &gt;1lati xsao yi i a: d.-: is: e'd. .1. ceec daddc.e e :s s S-S:Ss's pr ss c.ses a a es se SSO soas :i á asa d&lt;x s xeg :7·Τ ;Λ7' dC dl .. . o·': ... .; ..'vbvC sèrsaxca. di; bá a co ssdxaxsaaa d;· assa si g..,l .·&gt;. X ss ÇS a · a aos s xsbsd.essss a assas: s&gt;x Csisas i ieO sst ssqo.1 f A, ib,· F Tç v Ma ssss ia ddéiT d\ a :·. V Mcxai ãò a; ' :·' i :ls a&amp;aa :di SS &gt;,H _a ::'dpd .raSiíoãa .1 .frdrs aaxs aaxa C ΤΝ· £' xa ga.s CSX r si ca if.axss;g d Cd? Cisco i X CsSS.C SiSC?'S Tp. F';7 pdad a a Svd H.Hí Ç tor ip· i\xi. i. is , XSSSÍ.SS o s tCi. í :i οχ,.; t aa.i seca esssa ,:b MaatC saox. 33 ss s x OOâ '·, ··&gt;. ·Ί &gt;7. . • 1' .·' . d &quot; ·;· ia -a d} v dJ. cassa 1 as. ide i'·· ida Iv ! O ia Jidad......... abri iássabasc sxgs* a.s.:á: a-aoa Π': ;&quot;··. I x&lt;x dl.sddj Ç lê a C 'Os:,· CS que cs a Caxas.a oeee o· :deciis. d.iaàa iv C) vi sassisc? ab ;'\b;S&gt; d d'' aaxt: .dl :'d 1-7 d ds c ie cce sxaatás id isi T à à' :d d’:·· id .V vis-idii-ba 71 .d- da :. de px XisSS sssaa: P ^ ~ SC Si C sla p caasas: s áXixisCea báX Xdi y.......0'&quot; Siísse gxsssss , ·.·&gt;;:: SC: SS SSO C· O iii o ,rr ia ddG X ca : de. psss:' •ds s;x as SS SS áXXpS .SXáp sa;s po..a .:.! .ss atsssa; si,· ersí. Xgua.T.M saca ia·· iiòlv ; sss. i. a sss ;. Τ' 1 :dé. i; xsstdaSssU x &lt;a ia gss e asasxarcxsxis: SXSXá: Hf Cssia iplàdi .............. eo. eva .de psrs: L O fSCX: MS ddlacai Cd ;a divCie as a g 11 ge sa.e. i áx? sL; a poasoate i.grpssçâo. pssopaa asa praoosso xrstagr&amp;do éaxssoaca.o a a:xaggsxáíea;caa; o.sx&quot;·ao.cx;s passea. a psaxxra,capai o as gaaaa as aa:a.áabaái,a a X'aa'sx&gt;c:àss ds CG;.&gt; ax.xxsbs.as.ssac..' as xox lect χχχχχ ÕXX D X.XXajXXXí •ae· 1¾¾ xaado o xaeoaa xecax ai o lox xax da cooe exaXxo oxatoi auaexxta. s iorca xaatria da coe a x d a tsx t a Its a d t a á t d a sxa d és. lax c .1 a a a a χ.χχ·ο a x ca raxxepor te, fccta.:. da e xaixdraee caxxbáxiiaa a r:exeabeciâa pala caxaaxai ca: de eixaxtitxxxa acaaa teaxlo a xxapaeidade para a ata x ia ar da ioxxxxa revxrsiaal a reacçao da cxx.aa:exaa.e da dlôa.idxx de eartead exx i:d.xxaxxboX:xsio &gt; ..a ρ a £; a exx oe axxx? aixp a ο ρ xx op a s uxs ρ a oxx a a a o .xxx r ia xxa ca (aba a: r a ao a r a a ao a r a c a c a x ml d S n a a a} xx a a ode c axx t a a t o r e a da axacbrarxaaí x.X a iaa;òa a xxbéer ao οχβχοόο íedxrioe xacoxpxastxx dl a de r j:Xx ae xxxi c x tx' da r eaadaad a n x? a i:e οχ. a .d ·-··: padvxeoxte oaxxaxxoe a araaaaaa xxse xxxiaxxxaaaeâe eiai CbtVw &gt;.The process of redoxing is the same as ssaa; of the most &gt; brao.sa to afo oossss. of Pd d &lt; saass sds a eo 1açdaa ai s :: &lt; exit the s aseixso sa sa: 'yai &gt; 5 · &amp; as &gt; 1lati xsao yi i a: d.-: is: e'd. .1. S S Τ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ Λ. O·': ... .; ......... di; bá a ssdxaxsaaa d; · assa si g .., l. · &gt;. X ss ÇS a sssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssss V Mcxai et al; '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' '' ' Cisco i X CsSS.C SiSC? 'S Tp. A method according to claim 1, i. S, S, S, S, C, Fig. tb______________________________________ tb______________________________________ tb______________________________________ tb MaatC saox. 33 ss s x OO ', ·· &gt;. · Ί &gt; 7. . • 1' .·' . d &quot; ......... cassa 1 as. Ideally Iv! The Authority ......... opened the doors of the doors to the door. Ix &lt; x &lt; / RTI &gt; &lt; / RTI &gt; d.iaàa iv C) vi sassisc? ab '; S; d d '' aaxt:. dl: d 1-7 d ds c ie cxa sxaatás id isi T a d ': d': id id. X X X X X X X SSSS sssaa: P ^ ~ SC If you slaughter caasas: sXixisCea baX Xdi and ....... 0 '&quot; Si sise gxsssss, ····································································: pssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssss .ss atsssa; Yes. Xgua.T.M sacá··· iiòlv; sss. i. to sss. Τ '1: give. i; xsstdaSssU x &g; a &g; &gt; eva .de psrs: L FSCX: MS ddlacai Cd; i.e., sL; the poasoate i.grpssçâo. pssopaa asa praoosso xrstagr &amp; o.sx &quot; · ao.cx; s strolls. the term Xaa is as follows: Xaa + Xaa + Xaa + Xaa + Xaa + ax.xxsbs.as.ssac .. xox lect χχχχχXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX s iorca xaatria of the coe a x d a tsx t a d a t t a a sxa d és. lax c .1 a a a a χ.χχ · ο a x ca raxxepor te, fccta.:. of e xaixdraee caxxbáxiiaa ar: exeabeciâa pala caxaaxai ca: from eixaxtitxxxa acaaa teaxlo the xxapaeidade for the ata x ia air from ioxxxxa revxrsiaal the reaction from cxx.aa: exaa.e from dlôa.idxx from eartead exx i: d.xxaxxboX: xsio &gt; ..a ρ a £; a exx oe axxx? aixp to ρ xx op to uxs ρ to oxx aaao .xxx r ia xxa ca (a to ra to the araca to the aracacax ml d S naaa} xx aa ode c axx taatorea of axacbrarxaaí xX a iaa xxbéer to οχβχοόο íedxrioe ?. xacoxpxastxx dl RJ: cx Xx e xxxi tx 'r eaadaad anx al: .d and the οχ · - ··: padvxeoxte oaxxaxxoe the araaaaaa xxse xxxiaxxxaaaeâe eiai CbtVw &gt;.

Ha ata coxxx.bqxxxaeâo, a; corrente, de gas ax;a coo.tbo dia caoracta eo:e, ; xxae. acinpac eonatxitxxida xxxax ixxa.odxbxS: xbogceexxix oxstdrab autétiaac cae axra aeixexdade aa âgaa adeqxxada a a.; axxaxxsa aaxdraae oarodoix-a - d (t.t· d transa cortado :oaxati.aaaaacto da aorraote qaaoaa da a n a a t a a i a a I a ai&quot;a é a da a e.X. i xoa a een a 1 .X i :t a x d a p er i‘i. i ga. x d ae i b XX: 1 a e p: axx xax a t a r a ar a: ai b t ices ao x;: t :eo de a a xx a , l.xsa axx 1 dxx a a a caxxddnáaa, bata aotacao b xxageaeraaai á texaperabara xaxxhxeote a qaxxx se raaxàxe Xxxxxxaa: oae ácxóráxXav&amp;o de ·€Όν na e:.b x: p o le a bs o :re axx: d ço e ai: i a :ado a: a:a a: dai axxa ç ã e...........(c xxxxxeHa ata coxxx.bqxxxaeâo, a; current, of gas ax; a coo.tbo day caoracta eo: e,; xxae. acinpac eonatxitxxida xxxax ixxa.odxbxS: xbogceexxix oxstdrab autétiaac falls ax aeixexdade aa âgaa adeqxxada a a .; axaxaxxa aaxdraae oarodoix-a-d (tt · d transa cut: oaxati.aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa a . e xd ib XX: 1 PEA: XAX axx atara air: bt al ices ;: x t: aa and XX, AXX l.xsa 1 dxx aaa caxxddnáaa, beat aotacao b xxageaeraaai will be texaperabara xaxxhxeote the qaxxx raaxàxe Xxxxxxaa: oaxaxxaxxxav & Όν in the e: .bx: po le a bs: ax ax: a nd: a: aa: ax ax ç ã e ...... cxxxxx

Xxaoíxtacx? xxaa 0:0 XXxaç o a a pxxop· aadaa axxta rXexxnaotax . baa sao xxioseaaari ae d ixild aixe. ;xatxxraa ateaaaaa P a xx a xx e a e n a xx a xx o 1 iq-xxdo ido ia 0 i 0X5: a. xíxistas &quot;a exxtètics o iporapo a araaaaoXoxoxixx? xxaa 0: 0 XXa c a a pxxop · aadaa axxta rXexxnaotax. baaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa ; xaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa a xíxistas &quot; the exxtètics the iporapo the araaaao

CíUC capdaaraakr, fo.;: aartro lado, p cori'F.ude de gida tratada?.,· aee aeear da didaaidaa de ceéí;;o:n.o aaieqae:rdi.p: eode der 3X ci Irada. o o : 033-03- 33 :0:13- 33;&gt; 33 ale adiai ema lll.P ala a ode letal) :-ρ: ll te a cc aataáoqiaa Ç 330' : dO y â d ta; 3; 3 ::aao po ia i as liquido aaomo: a íap: ΪΛ ania tara 1 Idfédica t· Piá: aaaá a 333 33 ::aadP daí a ap 3333 Ϊ3 (3 dl . 3333 33:33-3-0· 033 1. λ .; deaeirip 333 uaiilo foi. deAueiedra:de &gt;3.33 li. .·.. i' rad ura. a e ;qqa.oi:da.í 33/.: 11-: a liaed,d. e 1. OP-.: ice í ['CíMI-Ml. [a M] &gt; Í’J· 30 i. '1 dal 11 a ar : U a-a)ld •T33:&lt; d33.3. Ci 33.33 G 33 auardc 03Í-OXt 303003 si 3333 eia. oe :eea, do o eume.ato -do coe t. 3 33 3 r&gt;&gt;3 33 3. alud 1.1 idade dai Xo aea - , (3 '1; parra ara 33 Vldq 33’ 3--33 Ϊ3 33: 33C ae.-aeaq.rau: :ao 3.3 ¢3 erudexa .(0,1 ae.) / 3! 1 d. qe 0 do idraico ? : { Mooaa :' '· ai a eaq Ca , Aiodao * 1- d . Ced i d da Ò3 d :G (,330 id leiga: axe :/3 .........cdq..........c ddi: 01'3 a aleiearavq: U- •:3 a- d c -Ol: 330 OftV arai 0Π Iq autua :ta a te 1 i O.0.I 33' a,a q 03.3 i aáeMdappoa.,· de p:&gt;· .1 ‘ .1 f * IPad: ... i 2 d)i2;, d' c· q&gt; 1---11) ,In addition, the composition of the treated portion is determined by the method of claim 1 in which the compound of formula (I) is prepared as described in Example 1. or o: 033-03-33: 0: 13-33; &gt; 33 ale adiai ema lll.P ala the lde ode): - c: ll te a cc aataáoqiaa Ç 330 ': dO and dta; 3; (3 dl. 3333 33: 33-3-0 · 033 1) (a) (b) (b) (b) (b) The composition of the present invention comprises a compound of the formula: ## STR1 ## in which R 1 is as defined in formula (I). 1 to 11: 1 to 1: 1 to 3: 1 to 1: 1 to 3: d33.3. Ci 33.33 G 33 Auardc 03-OXt 303003 si 3333 eia. oe: eea, do eume.ato -do coe t. 3 33 3 r 332 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 33 (0.1 ae) / 3: 1 of the idraico: Moaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa : ax: / 3 ......... cdq .......... c ddi: 01'3 a aleiearavq: U- •: 3 a- dc -Ol: 330 OftV arai 0Π Iq (d) i2 ;, d '(i), (d) (i), (d) c · q &gt; 1 --- 11),

Pasce xçãcs geral da iavençào i aocessode .Pseea.ção descrede ara raroceesus .paxá rerropiio cie c ore o e iv o ;s uda I. c; e s, a oe e a d aos a a à e dl ,6 e ida d e o ar fc cor o, preeaad. ss re cçrrresss-e de gàe em eiacsrs.Ooa cie aras Pd erre a.; eoeiPieaado e capacidade de riqdidaa iisdiaoc oa, ad.etireae aptétieaa cera capeei f 1 cidade para acdruPiliaa.r dtopido de carPcrao cssss o uao cie uacs saco s.ma arredava se cerPcavi aao qo.e cedais a a: P: Γ d' di fg rd eopvpraãd de CC ea?. ps. earPeaedo. d a ate: Sirvfcfc a fc.iid fc.&gt; dPda; 'p .c C;vi de:&quot; sa :S tísecaesesd lo de. emairsa; aridraea O pi X'. D Ο.Π .'i .ÇsS ΐ e.p s.;i.qe.1:df '.r^' idbii.i.drdeip OIc lí .i o trar a.a ae t é d r da.a coe ei era. d a id. e i de de pera sseeorer e e 1 e c a i o ascee t a CP :í; &lt; êdraae , &gt;q de alsiodss 'fcà-çi dlCfcp V.a .CUp Qpr adegeada ea âgoa á pCíCaresl d.iapera a.r a oesadma a.aid:raae aarpdeiaa ÍPC); arre liquido lóaicoe ou eietera eutéalco, Oe iiguidoe icasicer,· ,c.;ersgep ee o cope xgar opa; r,pae r,raaieriae oa espe ci e a r.o.a.rc»is eXo ÍU'Ò çpptsrpirra. o seca ; d K .· .soado ;p xm, o a ar ao ercaaes.ee; e Pd issa aeleo igorgâisioo eu orgiaico. Por digfctsidsfcip iedid p ;pi X:‘ çiX-i' íScçcs pr e: css ao ess eagez mus. te c a ira pockor eess aoedoss gsrer ep. sseaàarssrra s 1. igc:csdaa íssipor ePo'i.r.P s í|;ae.r e:o eorvaacdores de aremOs· assas, orcdoisdo-ee rsaeo re ase cso. a c 1 aç d « e: ê e fc tem a me ir té e e t d s? e i P· rim a sedo aai eo d t: a d t o dom ceareeaee eeeaaepv d uao de ladaeirclps ida. ice a ep 'misaeraa eurpaicaa cem i mreesfcro da ugpoa rmrito Paira; ocas a paxaicccfca r idade de eoaceaamarem e eoiaPilirarem OCP, ae case asar e amasie o. t e 'perfeita pams a sus arme, a ase g'a raassP· uma esesusdà cp:esusssarucg.o l.ecel da ΡΟ·ν ss o armer ele água. eedeaedcaio gap: garante casa adequadu a.at ia adada e ea cepi.1. idade da enalaa* Bedte môde, alee; da maior soiaB c, XI de d e de COs a ase e. τ o a mi s? dera. eea è t i c a: a ar ec a raro a &gt; o srmcaas.emo ees.erea.as oe coaresseao eae ma a a ca de Cdi: em Ba.careoaeto assmeeta a Porca mearia de aaaaaperta 0X0 ΧΟΟΟ':Χ a I g n i. i.t xra t ler a ara ax t a a t r aa a £ a r a ? raa a tX&gt;í: ' \ΰ·3 t.a. co - .v ai.!· Ú.' pá^;d:.vÇ: p ia .'iaaia Pv da a xxt)S dá d&gt;^ a ir a· a·'; .·&gt;'ν ' ·- Vr ' Iciti da a a á i v ΐροΗΐ aoX acõa: .a atar ae se xxxxlrx: á-ui ae c aram itaarxai arda a .1 p dtp xrxax asa: x da a a xam; liaiaa rct d.&gt;p· rxxxxr xu Pa U · ao iaa rpp/ I talar 6 ρ ate il\&gt;! a uaaaa dtp· ap e; xx L pai LI i.X :XO.S dea D xe.f xexx lelOla •tl ,ΧλΪΧρ; ;l .xare r: xecra cu arxioaxaixaB ex.xx.ixxxaxxxxas acaa xarasçxera. axe. x:xa.çxaxxaa paxas a C Ce .· ííaa aapaa::iaa.ci.a.a reeaexxLes dai ρ a.sxaarr atoada aaa gaxea aa exaasa gu.oiraxr da u: r sxa ap a.e a a. x. ο x.x p· a: ρ a aaapdaapao gue aeccux&quot;tPta vh.;«.x.ív..s',í: ..·. :.·· (..n^í-j-sís ¢1.¾ h^vhí cív.;&gt;. a λ a: xsaxxxx rgáaaida aeolaicecto da·: a exxxax pacto, a a a meado par.a aa · : a ç a . xxx ç a o a ax ρ ag .: ca ti ao láaicíaapa Ig xLe:a ar. aa raça i.oaj,caa aa a earxara a a .ap.de afiai d: a d e: ρ a. ta C 0;.? ,&gt; E ate ai ta I dada pado a t a d. a a a a selhorada. aiaaaaa da. ararpeae da Ilxsatdrre tdxxx .x.cxrx-x Lraaxeados rao a gaaxáXd IMo, ca ateado eern prupo ereta; r tá a til:: lx ditÇriO dea tárd aáxtdt Laxa Ox ar. X a a. de Cil; ••'is- Xfii iX v'X çi diai pi: i&gt; rp tx Ç pi ide cai au.rá. a aae d ar apiá contendo· a at;xi:a.a x. xontra-tâí. ; d-S axna.do fe iaa x iax aatt camea t a , axxrdarxa.da a ata tagaologia paraxita reaelaat a paodlaca da .xreaarçáo da aatgraafcaa taalaxaa peaeaaxrLas exrx ai.raaaiàoa da aa-eaioaia^ pa:.a.ida;dx&gt;:p.ip:Xp;d:p. ia ρ c pa.. da ara d οχοχο axd c X err t a a aaataaxàaaXí corada o .Lipui da iarrica au &amp; raiata r a xereta a r ca, taaaaaxadoa paa daurptpria da CO:&gt; xraaxxdrr pteaaiaa X Uxár:tidá OU rrá&gt;: :p::iá: dá aPCpO tΟ XX tig U3 iâ :S :X P f de casas t;ôxio dos s gontactor odctasbor o • i; ρ:. 1 [bg pi. p *Γ·W-íUO V'1 &gt; o r egaço .r a doGeneral steps of the plan and action of the Plan are described for the rare occurrence of the disease. and (e) to (e) and (d) to (e). In this connection, the present invention relates to a process for the preparation of the compositions of the present invention. eoeiPieaado and riqdidaa iisdiaoc OA capacity ad.etireae aptétieaa wax Capeci f 1 city to acdruPiliaa.r dtopido of the UAO carPcrao cssss CIE UACs s.ma bag is arredava cerPcavi AAO qo.e give in aa: P: Γ d 'GF di rd of the CC and ?. ps. earPeaedo. (a) to (b) and (b). dPda; 'p .c C; vi from: &quot; S: emairsa; aryl. D Ο Ο S S ΐ ΐ ΐ ΐ ΐ ΐ ΐ ΐ ΐ O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O. d to id. and for example 1 and 2, respectively. &lt; (a) (c) (c) (c) (c) (c) (c) (c) (c) (c) (c) liquid liquid or liquid eutochemical, and the like and the like. r, pae r, raaaaaaa, or the specie in the rhetoric. or dry; d. and you're an orgy, I'm an orgy. By way of example, the following equations are given: te c a ira pockor eess aoedoss gsrer ep. sseaàarssrra s 1. igc: csdaa íssipor ePo'i.r.Pe.a e.r e: ecause of effluents, waste water and wastewater. a c 1 d e e c e c e c e c e d e c e c e c e c e c e c e c e c e c e c e c e c e and i P a rm a s a tio n and the d a t of the dom cearea eeeaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa. the epidermis of the eucalyptus is the one of the ugpoa rmrito Paira; and to the OCP, and to marinate and knead. t is perfect for your weapons, the ase g'a raassP · a esesusdà cp: esusssarucg.o l.ecel da ΡΟ · ν ss armer it water. eedeaedcaio gap: guarantees adequate home and adi e and cepi.1. age of enalaa * Bedte môde, alee; of the largest soya bean, XI of d of CO. τ or me? dera. eea è t i c a: a c e c a rare a &gt; The following information is provided in the accompanying drawings and in the accompanying drawings. i.t xra t read the ara ax t a a t r aa a a a a? tx to tx> 3 t.a. cov. (a), (b), (b), (b) and (c) The method of claim 1, further comprising the steps of: (a) reacting a compound of formula (I) with a compound of the formula: ## STR1 ## wherein X is as defined above; Î ± β⠆ '† † † † † † † † † † † † † † † † † † † † the uaaaa dtp · ap e; xx L L i.X: XO.S dea D xe.fxexx lelOla • tl, ΧλΪΧρ; ; 1. xare r: xecra cu arxioaxaixaB ex.xx.ixxxaxxxxas acaa xarascxera. axe. x: xa.çxaxxaa bashaws Ce · C IIAA aapaa :: iaa.ci.a.a reeaexxLes give ρ a.sxaarr atoada aa aaa gaxea gu.oiraxr exaasa u:. r to the SXA after E.A. x. ο x.x p · a: ρ a aaapdaapao gue aeccux &quot; tPta vh. '. x'v's', í: .. ·. (A), (2), (2), (2) and (2), and (2) to the following: a a ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ao ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag ag. &gt; al rt and even until I gave pado d yyyy selhorada aiaaaaa ararpeae of the x-Ilxsatdrre tdxxx .x.cxrx Lraaxeados the feed gaaxáXd IMO, CA fired eern upright prupo;... r :: til the okay lx ditÇriO dea Amino Acid Xa to Xa of Xaa Xaa Xaa Xaa Xaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa :.. xontra-aa x Tai; dS axna.do IAA x Fe iax AATT camea rt, until the axxrdarxa.da tagaologia paraxita reaelaat the paodlaca of the .xreaarçáo aatgraafcaa taalaxaa peaeaaxrLas exrx ai.raaaiàoa AA-eaioaia pa ^ :. a.ida; dx &gt;: p.ip: Xp d:. ia ρ c p pa .. ara c X d οχοχο AXD err aaataaxàaaXí the cup stained .Lipui iarrica au &amp; raiata snoop air ca ra, taaaaaxadoa PAA CO daurptpria: &gt; xraaxxdrr pteaaiaa X Uxár: taken OR rra &gt;:: p :: IA, gives aPCpO tΟ XX tig U3 Ia: S X P f T houses, Oxio of s gontactor odctasbor • I; ρ :. 1 [bg pi. p * Γ Γ Γ Γ Γ Γ Γ Γ Γ Γ. the ratio of

Deecriçào das cagaras F:ígara lá, Processai .ietearsolo da captura prsoectes eo. ciroui.tçs de scestesra coai de asiobioiiias: iibs sáiiè. Mo sr:isiea.rs ρrase:ite ec ads ala sioostesèa. e pseibrapo: o «o secaode coosector o Ροοοί,όρ iôPdct circuita a essasao reduaida.Fecundation of the crates F: there, Process of seizure of the proceeds. ciroui.tcs de scestesra coai de asiobioiiias: iibs sáiiè. Mo sr: isiea.rs ρrase: ite ec ads ala sioostesèa. and pseibor: the dryness of the co-section the Ροοοί;

Figo.ra lb, Froaiesss lataprade de captara eraacates οτ5 oircditoa Ma apostasia coai da asses toa lo dois cositaciíir ca oep.braoae an acrsa., .to 1.01 i.o ii ι ο ο ρ o P- ca caos aaearxpãa de tal hada da, invenção .a prescute iasssppeea descreve eis processo pero a rorioçoe eiicledte de srsapDstoe; roa lasso,: noeea doesta te d is ei d o de ooaauaoeo.q- praoeocoes aa corraoste de eira ero cercaitas de a.msò.tà.s.lip coaidi d aedo a coqarcidiade da llorrldos iôoicos ou da '%: s ter o.a e até c re o. o e eοι e sp ea j. t :i c 1. d od U: pa p a o e 1. ub 11, 1 r er drdoàdo de co.rPoo.o aow o uso d.e urso: eaootca, aradèraec cerrroea cO ;, cota; cavarias a. r ao: coo do aosvereda dc? Cca as: bicaabadata,Figo.ra lb Froaiesss lataprade picked up from falling eraacates οτ5 oircditoa Ma COAI asses the two idle it cositaciíir ca oep.braoae an acrsa., .To 1:01 io ii ι ο ο ρ P- CA aaearxpãa such chaos hada the, invention The presumption described above describes this process but is not limited to the description of the process. It is important to note that there is no risk of damage to the groundwater in the vicinity of the surface of the earth. up to c re o. o e eοι e sp ea j. 1. A d u b u c e d e d u c e d e d e d u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u u a. r coo do aovereda dc? Cca as: bicaabadata,

Mo et.a proas soooop o eaateia ocaidrorae carteaica o dio se lai do. atuo i rpiripc rcjorco crc oo.saure eaa rarçOí çaa aptascate elevada scbaiferbid&amp;de oe bce,. :ee aedo a assegurar a aaaadil.idade ai a oeti visada: do. asriosp, e Travessar ro: que cate liçaido i ou rdeCdra ebecessa idos detsrrd.rio.da ac1i vi .a.ad e ái.s.á gaso,, ase va 1 ares a ρ 11. ρos a,1 da adps oa.pra 0, 2 e d, 8, d a a t o: p r o coe s es é a t o 2 d e. od e αν oas t aai e r do· se v:fes ora os s co.racterd.rade per u.ao ei evade sees da: tr eaar erêocia da essOa adp rebatida vaiada. Mo prado saco iiucedraslo praea:---so a: uriliaaicsle de dois a:aertaartorss 10 a 0} , pop. POTPsraaaa sare podes· sa τ ; poIirbasPs:as od. cer/âpiocas f coe taTaaoiOo da patota que podep vracbsr eaxre 0,02 ad erPaertros e: 0,5 ai crepes res, Este prevessa a ara:'o ctarrpa.de por lesar coatactax upo. icar.rau.ta ca tosa s uca s ti t al as par gases da v, : ;. v t a a«. v&lt; o pe r a a s a a e c o r a. ao s a a r e a s a a c a s r o e e r ,r a o. a ts CiOv NOS ou Pa irl , aup aoctactar de aeppraaaa is? asaegaeaiSbs a i aoisitLiiracao e ditaaõa des coTeposted saa o sap sçx o. caç. : ρ a r :a reta r. o.a e r o,ao,: o, de to ases aro e o.) que rstoarre o. erattuoa a.sidro:va· cariocaics. dlaparas. aora liguida idaitta ira tateò rriséTrre. sib::at.dcoq caro oiiilrridado pove pMo et.a proas soooop oaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa. The present invention relates to a method for the preparation of a medicament for the treatment of high cholesterol. in order to ensure the accuracy of the information provided. As a result of this process, it is possible to determine whether the product is in the range of 1 to 10% by weight or by weight. to 0, 2 ed, 8, daato: pro coe s es é ato 2 d e. d and a v a t e s of s and s s s s s and s s s s s s s s s s s s s s s s s s. For example, in the case of two carriers: 10 to 0, pop. POTPsraaaa sare podes · sa τ; poIrbasPs: as od. and / or pest control, which may be carried out at a rate of 0.02 ad erPerrets and: 0.5 crepes, which is foreseen for the purpose of damage to coatactax. and the gas in the exhaust gas. v t a a «. v &lt; the pe r a a s e a c c a r. s a c e s a c c e r s e r r e r. to C10: NOS or Pairal; The results of the analysis and the discussion are summarized below. caç. : ρ a r: a straight r. (a) and (b). erattuoa a.sidro: va · cariocaics. dlaparas. aora liguida idaitta ira tateò rriséTrre. sib :: at.dcoq expensive oiiilrridado pove p

Cta, o. fase 11 &lt;fa ida aa qual. o €0.&gt; ao iPdGis.tr a diasoIáMa íi; 0 a3J:aea3:.ada a ai. aedtrado ooiuãaitcav de rraasfcraoae {rq opa t a do a p r e s a e. o a edu a i da a t 3. 1. 3 a a ado ias d .oid e a a ado r (3. 0} d aiiá Ootstd da: aãddd 3 .i i} r ou doaddo aa qão dc drrdctd coes. cauda a ociitroèaaq ai c; a. U e a u o aaquaao oqyvaaetoa ;«.! &lt; o C'Cá a cápCurado a aaparada do uaa corronte .I.uqaida adá ocfotaa a ; anoiao a o liquido iooico oo ui a t ao: a eatétòoa (91 &gt; ; auadu audac alCiaa rofairoaiada para a prs ':rn aro con Oe.o C o.r í :: ; , ,3c aoorando ;.:. ff oea . o a. cã-cã no primo-ircf ooniaotdry 3 tio rd da d .1 dai do a ;a cardo no s 4} ... i ioda a C; .a a a: a .;. c a· cu aa 'p a r e: ο ρ a cO ) ate rd; .. a : al/oda pooa t vo.3 ΟΟίΟ acacadd; controlada d.a gao de aooatasia ti· o.a iorau a raptor a (iorspooioão do uáo da auoaieoia a adad,:no.ottar ao puuiaais,. aate ci.atooa ouita ooopJaataueoto a. contaod..no.o.ãc· do g a a c d'a do:dd i 1o d a oo r d· eu o e ao a3 i: Co t. do da io aavd caco t po: a a o liquido .ld;aia.:o ao ia .3 o Par a eito Pico: acia ursa prosono do uapor o.oa:ligaaaaç.lcaal &gt; dão alo ;uoa.eaoária.a: toaporaturao oiadddaa: o a r a ; r a q e d ar a r; a iloaidri 3.adiaã ou a rciadara aaad t.3 ca f pcrrqrJa a U til r a&lt; rqaa oa o roooao rodoaIda o o a ar. 3 3. á caça: a de : gãe- da or r auta aa a i r eal ia a fia per içado parai tal a. 3,:i.'da; rt ação do dl oaiuo oa carbono capturado * .!:Í/32Cta, o. phase 11 &lt; or € 0. &gt; to iPdGis.tr the diaspora; 0 to 3: 1 to 3: a. This study was carried out under the auspices of the Ministry of Science and Technology. (a) (b) (d) (a) (b) (b) (c) of this paragraph shall be replaced by the following: (C) the temperature in the range from 1 ° to 1 ° C in the range of 1 ° C to + 1 ° C (91 ° C) for example, in the presence of a compound of the formula (II): ## STR1 ## in which the compound of formula (I) a thistle does not have 4 ... ... iodates at the end of the line: ο ρ a cO) up to: a / oda pooa t vo.3 ΟΟίΟ acacadd the control of the disease of the disease caused the raptor to take part in the treatment of the disease in the treatment of the disease, in the absence of the disease, from the day of the month to the day of the day of the day to the day of the day to the day of the day. of the uapor. or the: bonding of the slurry: give the alloy; r a q e d ar a r; The method of claim 1, further comprising the steps of: (a) reacting a compound of formula the air is blown. 3 3. hunting: the following: a) 3, i.da; rt of carbon dioxide or carbon capture *

Baeoploe de api icaçãoApplication baeoploe

Eesaepxo X do 1 :i.eo.r do i xôo.i co X -&quot;-da X X i - 3 &quot;-a-o tb.il .ur; i d a solio 0.1. a i; e a: 1 f 1 aaro«sIdiaaosslPo.a 11} .Ooi da f [ ObCDij í 31330 eoo.In one embodiment of the present invention, the present invention relates to a process for the preparation of a compound of the formula wherein X is - (Xa); i d a solio 0.1. there; and 11: 1 (1: 1).

aad::d.b,dsáe eo. oqoo iodai a 0 0X53^ foi áisaoXalda a enbipo: liofirisada ardolra.se caa'ed'0:icas as. aoo:c:ea doaçao cia 0:,0.1¾ op:/p&gt; ,. XI 'Os.se ; Ilssida. coiratsdialda par llíprido idaloo e eirados. fco. iasdeilisada. sues osirdoaos h.idxoiófeica de OvOF, ooo taoaoOò de poro ideal. a 1.0 23 rd. erdaietros:, For eia s fardara dos oassios da paraaaoii iaada soa a ases puros, d adoido de oaaibosrr e ao o cor &lt; à taeperatars da 30*00 para a òesberaos. d:a:ir©fdo.i.oa .Ιΐτοοίό3.1 a. rada ©οο. llqod.dò ©baibo:, e perra a e.©:a.o rasas da oro sapo. ca. iieoPd. 1. ioada. cosx llq-u.itís ioar.oo a 011.01..00., Os rasarSados eupaadi©oivtals: dornoaotrarao lio aaasato eaoiia da aô2 aa selacaaridade ideal CfdbsP aaea d o a e n a i ria.....e a s aa 03 s aerr p e se. 3 a: a a 1 i. sai d a ioio b 1,11 s aata roas persas oa iseis©aasia. .·aad :: d.b, ds and eo. The reaction mixture was cooled to 0 DEG C. The reaction mixture was cooled to 0 DEG C. The mixture was evaporated to dryness. A: c: and donation cia 0 :, 0.1% op: / p &gt; ,. XI 'Os.se; Ilssida. coiratsdialda couple idílo idaloo and eirados. fco. was dissolved. OXOF hydroxylation, or the ideal pore size. a 1.0 23 rd. For the sake of the earthquake, it sounds like pure acoustics, to taeperatars from 30 * 00 to the òesberaos. d: a: ir © fdo.i.oa .Ιΐτοοίό3.1 a. rada © οο. and the bitch is effigy of the gold frog. here. iieoPd. 1. yada. Cosmetics and perfumers will be used in the same way as the optimal sealing of the seals and the seals and seals. 3 a: a a 1 i. it leaves the b 1.11 s to the Persian roots or to the aisia. (I.e.

Claims (3)

F E 1 ¥ 1 M D 2 CAÇO 1 B ; Χ \·;·ρ; ·· aY:i&gt; • i&gt;C' ip ix: Λ. txixd P &gt;€ -3.0- sde ΧχΧ:'·).ΐϊΧΪΥ: d&gt; s v PC tòc d.c 0 :3 ^ :fsi disde ido SÍ:Si t t'X5.,.v,; ,Xi òY-t-.c p prsp Cd Cd sx x sg a sxa GOCyX'G:C te da rois Xt ;Q . de: are s í - saia,: cass ' -:d X.' : tear 2 xad· D·: por Xa xer s.sas.a GOs create ρ t.x r.': t. .S C O CC-Ti X , 1: X. t o xda. ρ sir o ae : ase da &gt;';:· p-px;: d X Xceaa ac :.s:ioa Pa x o it aàalta ax.aate:G la. do, :X.GX C' 2¾ X;:S;S'G CscaCO a f òide d&gt;2.:. .sósircs í'\: d o a sad' s.dtrX X. xa 0' pis 3: C: oe C-: OXS| rastos ·.: sdo·; pi^Ó-S tdc X:: odí Pas: p. S:Sá;C; £ 0,3 0 sess ge.s aas os Gs-rvcaetar ao.ec; Geaca; CsXSCS ΟΡΟΧΟΡ difaeso r IXsluXdG Xoaxgo ou rsuea ssasie fure eutsat Xoa ,&lt; oots ra: a dx OXIO.Q xo GarbuXíO, pO CCxc, p :1330 i:.i cYi.Uc reco st da de a ta fase lipa coe os.sr bapuude r;S;StsXSOt;;G: à 3 p 3: :: .% -C Cd \.· .d d· foò. ,:. tt t,.·. 0x3 d· a cosarasxte Po s u.sc; G&gt;u..s: t ..3 .':X:'d'3:31:3 ao saparta t JGO r. .atai tciars 02.0:, seeso ps c.........3: (Y O a' xj Ct..........COO,.........3:·&quot; .......ÍV fp 'X se a. ΐ s oa. sx x; çe sa ,·.· ipala raaoçâp aeiaativa da dldaida d;a ; oatroa aampaatoa aateacd.a2a;aata tdaiaoa a u 1 a i t o a a a a t e a r a do, Ear&gt; a rat o a. a π X asa 1 .. .llsprida reedptPtd qtSb X.x. bagre a saoxbrsa a;o:Xrb::aae psarbexCca dx.spe.xsa nd:a a fiai dada pa aabaaaaenta ao a r a c x o :r ae C;G. ;:.5 a a eaoecs; a &gt; usaps; oc caraGt:ard.aadc ceai a.das 2 , das: procaPád da: ascaarda csaas. a a rei/yiddiddpõás 1 sa 2 ca.í ac r a a o x urso ca* x .*&lt; a ; roxa casa ;i.sa .; r csrarsos .igc ss. stos poasad.ssscso saras; saet.ae.Xsrxa geral ρ'ΡΓ ors asi starasa ;aatsat:ic;ar csgst sa 1 evade ρ e ta:P X X 1: darC :ge Xxa X. o a e t: õpp: X ca opg a c p a am caco agentes : da srarutdd d xaoar&gt; selasxtiea doa gases rsaXer ida t oa ; rc.Xc;xadi;xop2a 2 a coaxa amcsiaote para. estacar c xo ascsao cia cara: .'-.Pa. aro. a.x a.ca oarsacsaa, sae. * 4 * crs, pXOsaacee· da acordo· psaix a a :re.xixraxarx:a.s;pae?x ,1, a.F E 1 ¥ 1 M D 2 HUNT 1 B; Χ \ ·; ρ; ·· aY: i &gt; • i &gt; C 'ip ix: Λ. txixd P &gt; â € ƒâ € ƒâ € ƒâ € ƒâ € ƒâ € ƒâ € ƒâ € ƒâ € ƒâ € ƒâ € ƒ3: s v PC d 0c: 0: 3: f. , Xi-Y-t-p-p-Cp-Cd-x-x-sg-axa-GOCyX'G: C-lactam Xt; of: are s i - skirt,: cass '-: d X.' : tear 2 xad · D ·: for Xa xer s.sas.a GOs create ρ t.x r. ': t. The title compound was prepared according to the procedure described in Example 1. ρ sir o ae: ase da> ': p-px ;: x Xceaa ac: .s: ioa Pa x o it aàalta ax.aate: G la. X.GX C '2¾ X;: S; S'G CscaCO to fòid of 2:. ................. track ·: sdo ·; p. S: Sa; C; 0.3 g of the glycerol. Geaca; CsXSCS ΟΡΟΧΟΡ diffraction r IXsluXdG Xoaxgo or rsuea ssasie fure eutsat Xoa, &lt; The results of the present invention are summarized in the following table in which: FIG. 1 is a cross-sectional view of the first phase of the phase separation process. : -. Cd - .dd · foo. ,:. tt t 0x3 d · cosarasxte Po s u.sc; G &gt; u..s: t ..3.: X: 3: 31: 3 to 4: 1. ................. and (b), and (c), (b), the following shall apply: (a) to (b) and (d) to (d); , Ear a g the a π X asa 1 .. lsprida reedptPtd qtSb Xx catfish a saoxbrsa a: Xrb :: aae psarbexCca dx.spe.xsa nd: aa relay given for aabaaaaaa aracxo: r ae C 5, and 5, 5, 6, 7, 7, 8, 10, 10, 10, 10, 10, 10, x * * ro casa casa x x x x x x x x x x x x x x x x x x x x x x x x x x ev ev ev ev ev ev ev ev ev ev ev ev ev ev ev ev ev ev ev The compounds of the present invention may be selected from the group consisting of the compounds of the formula (I) and the pharmaceutically acceptable acid addition salts of the compounds of the formula (I): ## STR1 ## in which R 2 is hydrogen; staking with the face lift: sas, leaves. * 4 * crs, pXOsaacee · of agreement · psaix a a: re.xixraxarx: a.s; pae? x, 1, a. 2 s;.Gi;raetorr xePsa por o.t XX..I:.aaçao da X IssprX sirc; oco:; a sasis trsrOc.rass sas-uec i .ca. y r ,· saee pooexx oex os..;.,;,:s;:a.s,a o o ;a :.χ..·:0 s .ss: x- a axx drsíx c unidade datXPirica. y’:: pode acr atia rxxxdePsa p r a: X d rao ο la I eeo X a d o td' p c íMx da a d 11 ο, p X r ae ô .11 cg p :X χ: i d i O 2 O s p X: X X 01X d X XX X O , C f eCLt 10 ÍO .,· SXG X XO X G Su 00: &gt; P X p o: r a. a 1 xota ; t t X a o 61 i sa , a is a si X. X c * &amp; &lt;ars x e t x i a x 6 1 i xx q c a o d.:. ,i o f t a t r a o d 1 i, o, o u .1 b Pxs X .a * ersp xs X a &gt; f &gt;aa t Pxs i: ο p p gaat: i. dl xxi a s a ; aa? q α a: pn idade ao. X: 6 xx.X o a: d:: pa da a a x s.sd x,;a. J.:;X: qena gsx.v o sx; o xxs íxa, q xs sx asa : s a.xsxxsa.oo. sx í oarrac.i.Graxo çssa x si r r o r o a x c x. o x a do f c x c x c oxs ? c acara x xs ; six.c x a π asxx c -x ^ ui.OGlada'tP&gt; ; tx:dyxXa;Asc:;ata.';xixJc; Xdsxxxatxu axxadatof C x X: X Xsxgx a a ac: d a d c f: 0 x ! g 1 sia:c a íxo da do &gt; p x a p ions a· X o ,s d:o c aeo ac «&lt; íxafeaxxsia ta f íaaX.:.s..X xsx 1X a .to, sx ti x sal fada ^ propi .1. o a.X f sss ta.,· dot X1 xX;iX ta to í ioc t χ X: sol f a to ,· ta t il.ato # bex:s terííxoul X.ca.a to&gt; ts ;si a X1 a t o ? t x X f X a to ^ e a.:. t a x o f- X; .X ú r o sx exsa t a srX x a ta ,&lt; Od ttrXX ;CS t O: f ts X,t; X t XG. X: .X .OG X OXísá t ;Χ X G P2. t O o .1 Xs} X d: X^ dt ? G á-X XS b: XΡ ΧΧΧ Λ&lt;.. οο οο.χ·|.χ.;ο. to.,· abeao X Xa ta. t o ?· Xs a t a f i. iist x g Xoa f a.r o:í: f esc f a t o s d:.U:s X drogarso f os dato, is.sldoopenefas f a ta ^ 'tet r e..f luorsssbar a to s t A t X a X c π X X Po r X p p; ^ córisti fcuidás paa.a. ;ΐθ555Ρ5.θ:ΐίΐΟο do. ca .5 5.00 5,d:::: dl····} o srdid&gt; t i. ou r a .1 a- .3, &gt; 53 - d a a? e t i i a .$5 a 1 a &lt; !í: 1 - d ima. t i.2 s; X-ray diffraction by X-ray. hollow:; a sasis trsrOc.rass sas-uec i .ca. and x, x, x, x, y, x, y, x, y, x, y, x, y, y X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X XX d X XX XO, C f eCLT 10 IO, SXG X XO XG Su 00: &gt; P X p o r r. at 1xote; X is the same as X, <ars x and t x i a x 6 1 i xx q c a o d.:. , X is an integer from 1 to 10, f &gt; aa t Pxs i: p p gaat: i. dl xxi a s a; aa q α a: pn age ao. X: 6 xx.X o a: d :: pa gives a to x s.sd x, a. J.:;X: qena gsx.v or sx; o xxs íxa, q xs sx asa: s a.xsxxsa.oo. X-ray, x-ray, and x-ray. o x a of f c x c x c oxs? c acara x xs; six.c x a π asxx c -x ^ ui.OGlada'tP &gt;; tx: dyxXa; Asc:; ata. '; xixJc; Xdsxxxatxu axxadatof C x X: X Xsxgx a a ac: d a d c f: 0 x! g. p x a p ions a · X o, s d: o c a e ac ' X-ray diffraction, X-ray diffraction, X-ray diffraction, X-ray diffraction, and Xa is the same as Xa, Xa, Xa, Xa, Xa, Xa, Xa, Xa and Xa. ts; si to X1 to t o? t x X f X a to e a. t to x or f-X; ............. X t; X t; X t; X t XG. X: .X .OG X OXísá t; Χ X G P2. X 1, X 2, X 2, X 2, G a-X XS b: XΡ ΧΧΧ Λ <οο οο.χ · | .χ.; Ο. ., · abeao X Xa ta. t? iist xg Xa f f: f: f: f: f: f f f f f f f f f f f d d, X pp; ^ córisti fcuidás paa.a. ; ΐθ555Ρ5.θ: ΐίΐΟο do. ca .5 5.00 5, d :::: dl ···} o srdid &gt; t i. or a .1 to .3, &gt; 53 - d a a? and 5 to 1 to &lt; Fig. t i. 3. $ x r o x, a&gt; a da- t ais i,*á a &gt; :bo5xaa:o:0:la, ; etrloi3.oql.biol:: 5x:Lba*ir&amp;l f .2,-2^.2^- tri 1b.aurGaeetubiç&amp;í imidaaoi.eí d a ida adipica,· ácido ígeaoai.cdt aixo.Po aitriaUí áxaida jçalóui'Uof ácidc 5&gt;&gt;o;x Li ci* :-acc. O-d ροχ-,χ.ι oxioixicio - acedo .31035355 5,0.350505,55730, íic.:, a 533,55 çe dpoá.dipdí acida levullóióGí· cxllipl:# aortb.to.b acido toitáxxico oo ixoosloxbldo d d p-ila coxxxbiivagaa da- arc.i.a xs cha 3. 3 pa. dbbr-p- BBbbç texxã -d , cioxxoi.o Pe tpiadei·&quot;· cl acoc3;. í 1 a:oddi a, c 1 cr c l a do d icct li '-boo a 3.1 - Pi d.ro&gt;; 3. c t.t laiiiiod o C loxcatc d.a tr.1 f cai 3. ~ι.·$οΧχ3 3. f :ia f *153 i*l o, íllal.oratd í3a r,daco. í&gt; v ici dixocaccd do acaaaaa coxa aa :5:0,1355,30:15, catcioa a a 3? a a r -ac 1 cx 3- a aoo ρ o ,r o c 3. i 1. a a ç ao o c co o 5. a c 1 ao c % cou 5*5:153513 ra.aas: o pon;! a a *155303 c 3, *73*50 3.', xro a : -oc coro aioo o aioag &gt; a caí a ;pr'a.fcrP3ePÍalòxdpP.P c.aao:rao ggxxa 0,- d l&amp;èoráxaetrGC 0 oaiorca quo 20' aaaddgatxrcfí,· çc p-mP6P&lt;B&amp; o cdíitacto optre* a :laac pacccdí· *p5 0 coro 3b. a o*afero: 05350, &gt;iac capo r 1.1 ciac da 3;a.o d raua,, a a.; ± a. ao 3303c o 3,1 q*,* xi .do 1 Bxb. ad a 33: mi a: 3:0.33 a C33t;,étrca ooi*axi55io:oada:, *1:5355:10055$ do c caricia acldrcca 0ΐ53$'5ΐΟ3*:;Χν0Ρ 00033101303300 ΟΟΟΡΙΟΓΟΟ 003 00003 031350 a 0335510 prcficr ciioi clocxita ca gema. de D el Sob ip/xd a 2 &lt; 11 3p/p:;, 0 g 31 0,1 c i 130:33la 1 Pu to á 0 330 0 X 1 lo :i a, o go a t a 33 a g-emfo: i o31 a, 0 5333:: pr 01110 oa idx:; c*53crao 00533: 33a reicaíidacagòca aat*cr i*ar$$:0 cara iiter ioa.de· pé lo factò do* o IB.qdrdó i:b.$ic$i du 555ÍS 15510. O O 33 3313 53333*: 33 U 5·,33; C$1 53. OU 33 3.3 33. ,, ÇsO'SCO O 33.33.3.3 33. 33.33 33:3,.33-.-33: p Od.C 33 p &gt;3:3.33 33 33 33 a 33 00.1*15$ .33:1353:033.1,0 0**3 .133 33033 3.03: 5Í53 0:011.53 3.53:31: a: 000033303 33 a ΪΧ$0.$50Χ10 330, axrtoa dc cootaotar 330333 53 ooxorpsgoc gcaaaa do çiroPitò da a 33 O a 10:33.3:0 3¾ : ,p313 033:0:0:353:3,33 - 3330311. &gt;131 ¢3-1 -Sp '3,3330*3'.: '3 ,5, 3.33:33.3.3.0 .035! ic3t oiolO:3v da. o a tautara oo xo ca, d a 33:θΐοΡιο3θ;ο: pc&gt;&gt;r aocâo do t a i *c a o d o: o r e c iiâ ç s o d de t sir pa a c a a i 1 a i a: o f ou da t ar e c a 01*1035 333&gt;S:t Ctio ao - 0:33 por O Oicàd. 3100005 do :5333-10 033 3330:3,0 d O 00:0 0 1*11'O 0 :3 v 35 3 -35333 p r O O &gt;1:0 O 0 : *53 0 0 C33&gt; .33 d O 0:13335 O. C X 331 Pl5 0.3l 3.13 C:Ç dB C 6 0 7 ciirao lajiloado gaia. ai.il.iaapáo ad* aÍ:C333pra353a.c pollicérlíiac ca 3.30153 33qg3:3 35.ca 0 13350: 7*031|5&gt;33'31031:2035:-dlgs a 3.303311a33 O 013033310 311::t*135 3.1.1 S píll Í33:é'53 Í.OOa *1 3330 td3:&quot;1θ i O .133O35'O051,1 COO , 0, 3,:3:3 piGcoaa* 0 ;de acordo 0035:1:13: 5 01'11:1*131 pala 53ti 1i5 :t 3.1X3 1531:351-15:5 - : 53*1 1ÍP155*: 55353:0.3:3,15 ,;l lí l 53,51 Ií; C :OU 3Cdd:5l*lC oo5c aa roiocxidicasidoa anOecioroe :agáo do pò5i;a,i5C;c do poiibropao o.g :153:p r .35 533X0;*.; í 031 1:1011:153 1553 :1:0 - oaciraix 1 *.,* , 3:3335 p530033:0 0:C 53.553 , 0:5 31. a 33' 1033 *á a d C. 1 a *c t ér 1 33 a d o 33553 d. 35 .loa do 00353131· ar: a a: uar íp. c &lt; P&lt; ;/Cá O Cedo'/ -·3- vSia 0:t.!.X.iaaaào 5 l-.Vr 1.. 5¾ ci- O com rai.viad.icaa;;õea ãt; 'aa:.· O: a aia.a.s xa^aa* iX íi: aa-a· p; a p:r: G ÇP: G G 3 r podendo eeste ;,r dá _ ap; G G 'toa es iíéti 3 0 3; eo pa r ái slo 1 v Pa p·- GGC3GGGG dé· &lt; GCp GGGp p sr GíG as rei as.sdr.ça G· .'iãS aç B-t r Gis id-t 3. ;P páracd. as: l e a de ps;: G servas G O &lt; :ÍáiO eoísps :&lt;· :tea ;ã;Q à. Sp rli a d OS Ί':-λ tas e }. i p.a i,da Sal esc ir ááie.da , oa. dea ei;s a pr G SO p p\ p; P a doata«a .sãOí ctrí \·' 3 3 Ga PtP:. isááei io cie dás .3.3 9 sessa s S,dd stsetar da ÍSeáS: GrG sas á 0 v rases s s .ri.v.caa par ittédiibi· 3, sraa PO C O 3 G3 0 s-v por :BePdrp asa a aa o P are 3&gt;d a.Sí no qss ed. à cisada. CiSáSs cg .r Cdi r·, ·· ClG OSp: íte BS srast 3 esa uas UÍ a asa are: aedo r eds.es G dOí pr &gt;'-‘s is i. Í;i:S S n. G Issesta ets .a eas Cá a taca .CG sèa da eâ cae ,v .1 C ias P :rOCá:;áaO : de ao- a rd: a ars as reiriodisa e sea ao. t: 3 &gt;;· ior G S saraster i a a de po .d G iiheá st aça a d oa a; 3- 33G dá &lt;:&gt; ar t i íP 3 pa a a: o aso r a s t 3 asa pei ,3. aáca oept· ar:a &lt; straeá 3 da U a· i Ir rep G: G: de adidados se esd 3 3 p : 3· SSie s di.sá&quot; sataíá aís a 3 tilG oa aà pá r ol eia,: 13 pa recesso ds: e.cs ard o C: es·: ss a reisd.ads.ás rs sá s as 3 .r lar G :p ce:ra:Ç tari raso ·. 'spc.G : r ecr r e çi. G-Ga.v s da aesrr ;P&gt; s té pr 3 &gt;3 p;; .¾ d G asse tseI G v : çpí s is t r ar : assa s ta j p3'lG· reis: r S.CáS pr :q jpv; 3 3 G &gt;* .G.........:.3:3.3.......... adsdt ilc èGGd :ÍÇdá disecta ........: GO a ai &gt;'s: fift 3 .t&gt; aei CP da OU; adssic p S S&gt; ·' V; ao a a ap; sa adisãs canis tos ase c da na • P dás da as as t e ses t. ιρρο Pddas / pd3. $ x r o x, a &gt; the present invention relates to a process for the preparation of a compound of formula (I). : bo5xaa: o: 0: la,; The title compound was prepared according to the procedure described in Example 1, except that the acid addition salt of the title compound was prepared according to the procedure described in Example 1. 5 &gt; &gt; &lt; / RTI &gt; Preferably, the compound of the formula: ## STR1 ## in which the compound of the formula ## STR4 ## is added to the compound of the formula: ## STR1 ## in which the compound of the formula ## STR4 ## is selected from the group consisting of halogen, da- arc.ia xs cha 3. 3 pa. dibromopropane-d, cyclohexadiene, and the like. (1): 1,1-dioxide, 1,1-dioxide (3.11 g); 3. A compound according to claim 1, wherein the compound of formula (I): wherein R 1 is as defined in formula (I). gt; in vacuo: 5: 0,1355.30: 15, aq. (a), (b) and (c) to (c) and (c) to (c) and (c) to (c). â € ƒâ € ƒâ € ƒâ € ƒâ € ƒâ € ƒâ € ƒâ € ƒ1: 155303 and 3, (b) and (b) and (b) of the compound of formula (I): wherein R 1 and R 2 are as defined in claim 1, wherein R 1 and R 2 are as defined above. the copy opt * a: laac pacccdí * * p5 0 chorus 3b. Amino Acid: 05350, &lt; / RTI &gt; ± a. to 330 ° C to 3.1 ° C. 33 d: mi to: 3: 0:33 to C33t;, * ooi étrca axi55io: OADA * :, 1: 5355: 10055 $ c $ caricia acldrcca 0ΐ53 ':; Χν0Ρ 5ΐΟ3 * 00033101303300 00 003 003 ΟΟΟΡΙΟΓΟΟ 031350-0335510 prcficr ciioi clocxite ca gem. of D the Sob ip / xd to 2 < 11 3 w / w: 0 g 31 0.1 ci 130: 33 1 to 0 330 0 X 1: 1, the ratio of 33 to 32%, 0 5333 :: pr 01110 a idx :; c * 5350033: 33a Reaffiliates to the credit: the title of the invoice of the invoice of IBERDROLA 1555. O 33 3313 53333 *: 33 U 5 · 33; 33.33 33.3 33.3 33.33 33.3 33.33 33.3 33.3 33.3 33.3 33 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 33.3 15:33: 1353: 033.1,0 0 ** 3 .133 33033 3.03: 5353 0: 011.53 3.53: 31: a: 000033303 33 to ΪΧ 0. $ 50Χ10 330, cootabate 330333 53 iro iro iro iro iro iro iro 33 0 to 10: 33.3: 0 3:: p313 033: 0: 0: 353: 3.33 - 3330311. &gt; 131: 3-1 -Sp '3.3330 * 3': '3, : 33.3.3.0 .035! 3: 1. (a) the name of the person in question or the name of the person in question or of the address 01 * 1035 333> S: t Ctio ao - 0:33 por O Oàdàd. 3100005 do: 5333-103333030: 3,0 d 00: 0 0 1 * 11'O 0: 3 v 35 3 -35333 p r O O> 1: 0 0: * 53 0 0 C33 &gt; .33 d 0: 13335 O. C X 331 Pl5 0.3l 3.13 C: C B C 6 O 7 7. polyacrylamide adduct and polyvinylpyrrolidone were prepared according to the invention in the presence of a compound of the formula: ## STR13 ## 1: 1: 13: 3: 3: 3: 3: 3: 3: 3: 3: 3: 3: 5 01'11: 1 * 131 pala 53ti 1i5: t 3.1X3 1531: 351-15: 5 -: 53 * 1 1P155 *: 55353: 0.3: 3.15: 53.51%; C = O: C = O: C = O, C = O, C = O, C = O, C = O; 1 031 1: 1011: 153 1553: 1: 0 - 1: 1, 3: 3335 p530033: 0: C 53,553, 0: 5 31 to 33: 1033 * ad a. 33333 d. 35 of the aforementioned apparatus. c &lt; P &lt; The first part of this paper will be presented in the next section. (a), (b) and (b). (a), (b) and (b), and (b). G G is to 3% 3; and the pa r is only 1 v Pa p - GGC3GGGG of · < GCpGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG as well as the following: : I O O eo eo eo eo eo eo eo: Sp rli a d OS Ί ': - λ tas e}. i.e., from Salt Salt, a. (a) and (b). P is the amount of PtP :. 3, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 9, 10, 3 &gt; d a. Yes no qss ed. to the crane. In this case, the use of the above-mentioned components of the invention may be carried out in accordance with the invention. (I.e. G Issesta ets. A ct C a ss c e c e c c e c e, v .1 C ous P: t: 3 &gt;;;;;;;;;;;;;;;;;;;;;;;;; 33G gives &lt;: &gt; The composition of the present invention is characterized in that it comprises the steps of: aep a: a &lt; section 3 of the U a · i Go to G: G: of adidas if esd 3 3 p: 3 · SSie s di.sá &quot; 3 to 6 years, to: 13 per cent of the recessions of the following: Ç tari raso ·. 'spc.G: r screen. G-Ga.v s of the ester; P &gt; s tea pr 3 &gt; 3 p ;; . G G G G G G G G G G G G ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾ ¾. 3 3 G &gt; * .G .........: 3: 3.3 .......... adsdt ilc èGGd: Discrete item ...: GO a ai &gt; 's: fift 3 .t &gt; aei CP of the OU; adssic p S S &gt; · 'V; ao a a ap; • Can give you the keys to t. ιρρο Pddas / pd
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PORTUGAL AF, ET AL, Carbon dioxide removal from anaesthetic gas circuits using hollow fiber membrane contactors with amino acid salt solutions, Journal of Membrane Science, 339, 275-286, 20090512 *

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