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PT1061909E - Sais de cetoacidos e de derivados aminados e sua utilizacao na preparacao de medicamentos - Google Patents

Sais de cetoacidos e de derivados aminados e sua utilizacao na preparacao de medicamentos

Info

Publication number
PT1061909E
PT1061909E PT99907688T PT99907688T PT1061909E PT 1061909 E PT1061909 E PT 1061909E PT 99907688 T PT99907688 T PT 99907688T PT 99907688 T PT99907688 T PT 99907688T PT 1061909 E PT1061909 E PT 1061909E
Authority
PT
Portugal
Prior art keywords
cerezides
medicines
salts
preparation
amino derivatives
Prior art date
Application number
PT99907688T
Other languages
English (en)
Inventor
Thierry Bouyssou
Serge Biosa
Pierre-Andre Settembre
Christian Jeanpetit
Original Assignee
Chiesi S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi S A filed Critical Chiesi S A
Publication of PT1061909E publication Critical patent/PT1061909E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT99907688T 1998-03-13 1999-03-11 Sais de cetoacidos e de derivados aminados e sua utilizacao na preparacao de medicamentos PT1061909E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9803155A FR2775901B1 (fr) 1998-03-13 1998-03-13 Sels de cetoacides et de derives amines, et leur utilisation pour la preparation de medicaments

Publications (1)

Publication Number Publication Date
PT1061909E true PT1061909E (pt) 2002-11-29

Family

ID=9524054

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99907688T PT1061909E (pt) 1998-03-13 1999-03-11 Sais de cetoacidos e de derivados aminados e sua utilizacao na preparacao de medicamentos

Country Status (20)

Country Link
US (1) US6429229B1 (pt)
EP (1) EP1061909B1 (pt)
JP (1) JP2002506816A (pt)
AR (1) AR014714A1 (pt)
AT (1) ATE218335T1 (pt)
AU (1) AU2733699A (pt)
BR (1) BR9909651A (pt)
DE (1) DE69901689T2 (pt)
DK (1) DK1061909T3 (pt)
DZ (1) DZ2743A1 (pt)
EG (1) EG24397A (pt)
ES (1) ES2177250T3 (pt)
FR (1) FR2775901B1 (pt)
HK (1) HK1035856A1 (pt)
MA (1) MA24775A1 (pt)
PT (1) PT1061909E (pt)
TN (1) TNSN99032A1 (pt)
TW (1) TWI235059B (pt)
WO (1) WO1999047134A1 (pt)
ZA (1) ZA991982B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060128806A1 (en) * 1998-05-28 2006-06-15 Medical Research Institute Controlled release arginine alpha-ketoglutarate
ATE424817T1 (de) * 2000-09-19 2009-03-15 Dermal Therapy Barbados Inc Topische analgetische zusammensetzungen enthaltend aliphatische polyamine und methoden für ihre verwendung
FR2822704B1 (fr) * 2001-03-29 2005-02-18 Chiesi Sa Sels de cetoacides et d'acides amines gastroresistants et leur utilisation pour la preparation de medicaments
US7122578B2 (en) * 2001-09-11 2006-10-17 Alain Martin Method and composition for treating mammalian diseases and injuries which cause pain, erythema, swelling, crusting, ischemia scarring and excess white blood cell infiltration
PL372183A1 (pl) * 2005-01-11 2006-07-24 Sgp & Sons Ab Preparat przeciwnowotworowy oraz zastosowanie preparatu przeciwnowotworowego
US20110105617A1 (en) * 2005-01-11 2011-05-05 Sgp & Sons Ab Method for treatment of neoplastic diseases with alpha-keto glutarate and/or salts thereof
WO2009116546A1 (ja) * 2008-03-18 2009-09-24 国立大学法人 岡山大学 興奮性化学伝達調節剤およびそのスクリーニング法
FR2953719A1 (fr) * 2009-12-10 2011-06-17 Luc Cynober Nouvelles applications therapeutiques d'un complexe d'alpha-cetoglutarate et d'ornithine
EP2523669B1 (en) * 2010-01-11 2016-12-07 Inotek Pharmaceuticals Corporation Combination, kit and method of reducing intraocular pressure
US8476247B2 (en) 2010-03-26 2013-07-02 Inotek Pharmaceuticals Corporation Method of reducing intraocular pressure in humans
DK2807178T3 (en) 2012-01-26 2017-09-04 Inotek Pharmaceuticals Corp Anhydrous polymorphs of (2R, 3S, 4R, 5R) -5- (6- (cyclopentylamino) -9H-purin-9-yl) -3,4-dihydroxytetrahydrofuran-2-yl) methyl nitrate and processes for their preparation
US20140187815A1 (en) * 2012-12-28 2014-07-03 Guoji Zhang Process for preparation of l-arginine alpha-ketoglutarate 1:1 and 2:1
BR112015021870A2 (pt) 2013-03-15 2017-07-18 Inotek Pharmaceuticals Corp formulações oftálmicas
US20160250121A1 (en) * 2013-10-29 2016-09-01 Paolo Pertile Use of mono ornithine ketoglutarate (mokg)
CN106674057A (zh) * 2015-11-09 2017-05-17 江西乐维生物药业有限公司 L-精氨酸a-酮基异己酸盐的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3533M (fr) * 1964-03-05 1965-09-13 Logeais Labor Jacques Médicament pour le traitement des intoxications ammoniacales a base d'α-cétoglutarate de l (+) ornithine.
US4320146A (en) * 1978-03-17 1982-03-16 The Johns Hopkins University Treatment of hepatic and renal disorders with ornithine and arginine salts of branched chain keto acids
DE3438455A1 (de) * 1984-10-19 1986-06-26 Institut Dr. Ziegler, Bettingen L-lysin- und l-histidinpyruvat
US4957938A (en) * 1989-06-21 1990-09-18 Abbott Laboratories Nutritional formulation for the treatment of renal disease

Also Published As

Publication number Publication date
ZA991982B (en) 1999-11-23
EP1061909A1 (fr) 2000-12-27
FR2775901B1 (fr) 2000-07-21
DZ2743A1 (fr) 2004-09-05
EG24397A (en) 2009-04-27
TNSN99032A1 (fr) 2005-11-10
EP1061909B1 (fr) 2002-06-05
DE69901689T2 (de) 2003-01-30
DE69901689D1 (de) 2002-07-11
ES2177250T3 (es) 2002-12-01
DK1061909T3 (da) 2002-09-23
MA24775A1 (fr) 1999-10-01
JP2002506816A (ja) 2002-03-05
WO1999047134A1 (fr) 1999-09-23
US6429229B1 (en) 2002-08-06
ATE218335T1 (de) 2002-06-15
FR2775901A1 (fr) 1999-09-17
AU2733699A (en) 1999-10-11
BR9909651A (pt) 2000-11-21
HK1035856A1 (en) 2001-12-14
AR014714A1 (es) 2001-03-28
TWI235059B (en) 2005-07-01

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