[go: up one dir, main page]

PT1042340E - Oxima de 6-o-alquil-eritromicina b - Google Patents

Oxima de 6-o-alquil-eritromicina b

Info

Publication number
PT1042340E
PT1042340E PT98958055T PT98958055T PT1042340E PT 1042340 E PT1042340 E PT 1042340E PT 98958055 T PT98958055 T PT 98958055T PT 98958055 T PT98958055 T PT 98958055T PT 1042340 E PT1042340 E PT 1042340E
Authority
PT
Portugal
Prior art keywords
alkyl
eritromycin
oxyme
oxime erythromycin
alkyl derivative
Prior art date
Application number
PT98958055T
Other languages
English (en)
Inventor
Jih-Hua Liu
Stephen H Montgomery
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of PT1042340E publication Critical patent/PT1042340E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT98958055T 1997-12-01 1998-11-17 Oxima de 6-o-alquil-eritromicina b PT1042340E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/980,918 US5932710A (en) 1997-12-01 1997-12-01 Process for preparing 6-O-alkyl-9-oxime erythromycin B

Publications (1)

Publication Number Publication Date
PT1042340E true PT1042340E (pt) 2004-12-31

Family

ID=25527956

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98958055T PT1042340E (pt) 1997-12-01 1998-11-17 Oxima de 6-o-alquil-eritromicina b

Country Status (13)

Country Link
US (2) US5932710A (pt)
EP (1) EP1042340B1 (pt)
JP (1) JP2001525331A (pt)
KR (1) KR20010032688A (pt)
AT (1) ATE277063T1 (pt)
AU (1) AU1417399A (pt)
CA (1) CA2309963C (pt)
DE (1) DE69826520T2 (pt)
DK (1) DK1042340T3 (pt)
ES (1) ES2229550T3 (pt)
IL (1) IL136088A0 (pt)
PT (1) PT1042340E (pt)
WO (1) WO1999028332A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020070991A (ko) * 1999-12-16 2002-09-11 테바 파마슈티컬 인더스트리즈 리미티드 클라리트로마이신 다형체 및 신규의 다형체 ⅳ의 제조 방법
KR20020071012A (ko) 2000-01-11 2002-09-11 테바 파마슈티컬 인더스트리즈 리미티드 클래리스로마이신 다형체의 제조 방법
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
KR20030047873A (ko) * 2000-02-29 2003-06-18 테바 파마슈티컬 인더스트리즈 리미티드 클라리트로마이신 및 클라리트로마이신 중간체의 제조방법, 실질적으로는 옥심이 제거된 클라리트로마이신 및이를 포함하는 약학적 조성물
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6455680B1 (en) 2000-12-21 2002-09-24 Abbott Laboratories Methods utilizing aryl thioimines in synthesis of erythromycin derivatives
TWI246515B (en) 2001-05-30 2006-01-01 Abbott Lab An arylation method for the functionalization of O-allyl erythromycin derivatives
CA2533178C (en) 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
WO2005009364A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2006528190A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8758820B2 (en) 2003-08-11 2014-06-24 Shionogi Inc. Robust pellet
US8062672B2 (en) 2003-08-12 2011-11-22 Shionogi Inc. Antibiotic product, use and formulation thereof
CA2535780A1 (en) * 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
US8460710B2 (en) 2003-09-15 2013-06-11 Shionogi, Inc. Antibiotic product, use and formulation thereof
WO2006014427A1 (en) 2004-07-02 2006-02-09 Advancis Pharmaceutical Corporation Tablet for pulsed delivery
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
JPWO2007119717A1 (ja) * 2006-04-13 2009-08-27 大正製薬株式会社 アルドヘキソピラノース中間体の製造法
WO2007129646A1 (ja) * 2006-05-01 2007-11-15 Taisho Pharmaceutical Co., Ltd. マクロライド誘導体
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
WO2009019868A1 (ja) 2007-08-06 2009-02-12 Taisho Pharmaceutical Co., Ltd. １０ａ、１２位架橋型１０ａ－アザライド化合物
WO2009023191A2 (en) * 2007-08-09 2009-02-19 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of clarithromycin
US8299035B2 (en) 2008-05-15 2012-10-30 Taisho Pharmaceutucal Co., Ltd. 10a-azalide compound having 4-membered ring structure
CN102082088B (zh) * 2009-11-30 2012-04-18 上海华虹Nec电子有限公司 在直接化学机械抛光工艺的产品中共用sl掩模板的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681326A (en) * 1971-01-11 1972-08-01 Abbott Lab 9-substituted erythromycin a and b oximes
US3855203A (en) * 1973-05-03 1974-12-17 Abbott Lab 4{41 -o-sulfonyl erythromycin-9-o-oxime derivatives
JPS5896097A (ja) * 1981-12-01 1983-06-07 Taisho Pharmaceut Co Ltd エリスロマイシンｂ誘導体
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
US4670549A (en) * 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
US5141926A (en) * 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
KR0179379B1 (ko) * 1992-01-21 1999-04-01 찰스 엠.브록 4"-데옥시에리트로마이신 유도체

Also Published As

Publication number Publication date
DE69826520D1 (en) 2004-10-28
KR20010032688A (ko) 2001-04-25
IL136088A0 (en) 2001-05-20
ES2229550T3 (es) 2005-04-16
AU1417399A (en) 1999-06-16
ATE277063T1 (de) 2004-10-15
CA2309963A1 (en) 1999-06-10
EP1042340A1 (en) 2000-10-11
DK1042340T3 (da) 2004-11-29
DE69826520T2 (de) 2005-12-01
WO1999028332A1 (en) 1999-06-10
JP2001525331A (ja) 2001-12-11
US6194387B1 (en) 2001-02-27
CA2309963C (en) 2008-06-17
US5932710A (en) 1999-08-03
EP1042340B1 (en) 2004-09-22

Similar Documents

Publication Publication Date Title
PT1042340E (pt) Oxima de 6-o-alquil-eritromicina b
DK0891371T3 (da) 9-oximsilylerythromycin A derivater
NZ284846A (en) 1-substituted-pyrazolo[3,4-b]pyridin-5-carboxylic acid derivatives, preparation, use, intermediates and pharmaceutical compositions thereof
UA27105A1 (uk) О-метильhі похідhі азитроміциhу а, що мають аhтибактеріальhу активhість, спосіб їх отримаhhя та проміжhі сполуки
SI0680967T1 (en) Erythromycin derivatives, their process of preparation and their use as medicaments
NO951198L (no) Lipopeptidderivater, fremgangsmåte for fremstilling derav og anvendelse av derivatene
AP9801378A0 (en) 9-amino-3- keto erythromycin derivatives.
AP9801253A0 (en) 9-Oxime erythromycin derivatives.
NZ337246A (en) Pharmaceutical composition comprising amoxycillin and clavulanate
ES8800160A1 (es) Procedimiento de obtencion de acidos quinolincarboxilicos con propiedades antibacteriales.
HUP0004282A2 (hu) 2-Halogén-6-0-szubsztituált ketolidszármazékok
ATE71113T1 (de) Antibiotikum a 40926 mannosyl aglycon.
ATE186541T1 (de) Quillajasaponin-zusatz und diesen enthaltende impfstoffformulierung
MX9702666A (es) Nuevos peptidos con efectos inmunoreguladores.
TR199900661T2 (xx) Cilt enfeksiyonlar�n�n tedavisi amac�yla 1-hidroksi-2-piridonlar�n kullan�m�
MY101178A (en) Antibiotic a 40926 n-acylaminoglucuronyl aglycons and antibiotic a 40926 aglycon
DK312688D0 (da) Glykkopeptid-antibiotika
IS6559A (is) Notkun á azalíð sýklalyfssamsetningum til að meðhöndla eða fyrirbyggja bakteríu- eða frumdýrasýkingu í spendýrum
PL324690A1 (en) Improved therapeutic agents
TR199900662T2 (xx) 1-Hidroksi-2-piridonlar�n seborik dermatit tedavisi amac�yla kullan�m�
LV12172A (lv) Kompozicija organu kriokonservesanai um virusu un bakterialas infekcijas arstesanai
FI944563A0 (fi) Mikro-organismeja, valmistusmenetelmä ja käyttö
AP9801235A0 (en) Erythromycin derivatives.
EG18213A (en) Pharmaceutical formulation for the treatment of bacterial infections
IL115197A (en) Vaccine preparations for preventing vaginal infections