PT1030838E - Metodo de sintese de pirrolamidas - Google Patents
Metodo de sintese de pirrolamidasInfo
- Publication number
- PT1030838E PT1030838E PT98946678T PT98946678T PT1030838E PT 1030838 E PT1030838 E PT 1030838E PT 98946678 T PT98946678 T PT 98946678T PT 98946678 T PT98946678 T PT 98946678T PT 1030838 E PT1030838 E PT 1030838E
- Authority
- PT
- Portugal
- Prior art keywords
- reaction
- pyrrolamides
- synthesis
- followed
- cycloakane
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Tea And Coffee (AREA)
- Fats And Perfumes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6542297P | 1997-11-13 | 1997-11-13 | |
US7426698P | 1998-02-10 | 1998-02-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1030838E true PT1030838E (pt) | 2003-03-31 |
Family
ID=26745584
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98946678T PT1030838E (pt) | 1997-11-13 | 1998-10-21 | Metodo de sintese de pirrolamidas |
Country Status (35)
Country | Link |
---|---|
US (1) | US6262272B1 (pt) |
EP (1) | EP1030838B1 (pt) |
JP (1) | JP3497469B2 (pt) |
KR (1) | KR100386722B1 (pt) |
CN (2) | CN1508129A (pt) |
AT (1) | ATE231492T1 (pt) |
AU (1) | AU745788B2 (pt) |
BG (1) | BG64530B1 (pt) |
BR (1) | BR9814161A (pt) |
CA (1) | CA2310095A1 (pt) |
CZ (1) | CZ20001769A3 (pt) |
DE (1) | DE69810959T2 (pt) |
DK (1) | DK1030838T3 (pt) |
DZ (1) | DZ2651A1 (pt) |
EA (1) | EA002243B1 (pt) |
ES (1) | ES2186232T3 (pt) |
HR (1) | HRP20000298A2 (pt) |
HU (1) | HUP0100235A3 (pt) |
ID (1) | ID24135A (pt) |
IL (1) | IL135710A0 (pt) |
IS (1) | IS5469A (pt) |
MA (1) | MA24697A1 (pt) |
NO (1) | NO20002214L (pt) |
NZ (1) | NZ503916A (pt) |
OA (1) | OA11378A (pt) |
PA (1) | PA8462901A1 (pt) |
PL (1) | PL340554A1 (pt) |
PT (1) | PT1030838E (pt) |
SK (1) | SK6872000A3 (pt) |
TN (1) | TNSN98204A1 (pt) |
TR (1) | TR200001343T2 (pt) |
TW (1) | TW509675B (pt) |
UY (1) | UY25249A1 (pt) |
WO (1) | WO1999025684A1 (pt) |
YU (1) | YU27300A (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7092800A (en) | 1999-08-31 | 2001-03-26 | Neurogen Corporation | Fused pyrrolecarboxamides: gaba brain receptor ligands |
JP2004508359A (ja) * | 2000-09-06 | 2004-03-18 | ニューロゲン コーポレイション | アリール置換テトラヒドロインダゾール、及び、gaba−a受容体に対するリガンドとしてのそれらの使用 |
CA2430841A1 (en) * | 2000-12-04 | 2002-06-13 | Pfizer Products Inc. | Synthesis of fused pyrrolecarboxamides |
US6852730B2 (en) | 2002-02-07 | 2005-02-08 | Neurogen Corporation | Substituted fused pyrazolecarboxylic acid arylamides and related compounds |
US20080153629A1 (en) * | 2004-05-07 | 2008-06-26 | Sullivan Michael J | Thick Outer Cover Layer Golf Ball |
CN102786458B (zh) * | 2012-06-04 | 2014-02-12 | 天津渤海职业技术学院 | 吡咯甲酰胺衍生物、其制备方法和用途 |
EP3097095A1 (en) * | 2014-01-24 | 2016-11-30 | AbbVie Inc. | Furo-3-carboxamide derivatives and methods of use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750702A (en) * | 1993-10-27 | 1998-05-12 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands |
US5484944A (en) * | 1993-10-27 | 1996-01-16 | Neurogen Corporation | Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands |
US5804686A (en) | 1996-01-19 | 1998-09-08 | Neurogen Corporation | fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
WO1997034870A1 (en) * | 1996-03-22 | 1997-09-25 | Neurogen Corporation | Certain fused pyrrolecarboxamides as gaba brain receptor ligands |
-
1998
- 1998-10-21 CA CA002310095A patent/CA2310095A1/en not_active Abandoned
- 1998-10-21 IL IL13571098A patent/IL135710A0/xx unknown
- 1998-10-21 AU AU93639/98A patent/AU745788B2/en not_active Ceased
- 1998-10-21 EA EA200000413A patent/EA002243B1/ru not_active IP Right Cessation
- 1998-10-21 CN CNA031594727A patent/CN1508129A/zh active Pending
- 1998-10-21 ID IDW20000893A patent/ID24135A/id unknown
- 1998-10-21 PT PT98946678T patent/PT1030838E/pt unknown
- 1998-10-21 YU YU27300A patent/YU27300A/sh unknown
- 1998-10-21 TR TR2000/01343T patent/TR200001343T2/xx unknown
- 1998-10-21 US US09/403,985 patent/US6262272B1/en not_active Expired - Fee Related
- 1998-10-21 SK SK687-2000A patent/SK6872000A3/sk unknown
- 1998-10-21 KR KR10-2000-7005185A patent/KR100386722B1/ko not_active IP Right Cessation
- 1998-10-21 HU HU0100235A patent/HUP0100235A3/hu unknown
- 1998-10-21 EP EP98946678A patent/EP1030838B1/en not_active Expired - Lifetime
- 1998-10-21 BR BR9814161-9A patent/BR9814161A/pt not_active Application Discontinuation
- 1998-10-21 AT AT98946678T patent/ATE231492T1/de not_active IP Right Cessation
- 1998-10-21 DE DE69810959T patent/DE69810959T2/de not_active Expired - Fee Related
- 1998-10-21 PL PL98340554A patent/PL340554A1/xx not_active Application Discontinuation
- 1998-10-21 JP JP2000521068A patent/JP3497469B2/ja not_active Expired - Fee Related
- 1998-10-21 CZ CZ20001769A patent/CZ20001769A3/cs unknown
- 1998-10-21 ES ES98946678T patent/ES2186232T3/es not_active Expired - Lifetime
- 1998-10-21 CN CN98811119A patent/CN1280566A/zh active Pending
- 1998-10-21 DK DK98946678T patent/DK1030838T3/da active
- 1998-10-21 NZ NZ503916A patent/NZ503916A/xx unknown
- 1998-10-21 WO PCT/IB1998/001672 patent/WO1999025684A1/en not_active Application Discontinuation
- 1998-11-10 TW TW087118708A patent/TW509675B/zh not_active IP Right Cessation
- 1998-11-10 PA PA19988462901A patent/PA8462901A1/es unknown
- 1998-11-11 DZ DZ980261A patent/DZ2651A1/xx active
- 1998-11-11 TN TNTNSN98204A patent/TNSN98204A1/fr unknown
- 1998-11-11 MA MA25342A patent/MA24697A1/fr unknown
- 1998-11-13 UY UY25249A patent/UY25249A1/es not_active IP Right Cessation
-
2000
- 2000-04-26 IS IS5469A patent/IS5469A/is unknown
- 2000-04-28 NO NO20002214A patent/NO20002214L/no unknown
- 2000-05-09 BG BG104413A patent/BG64530B1/bg unknown
- 2000-05-12 HR HR20000298A patent/HRP20000298A2/hr not_active Application Discontinuation
- 2000-05-12 OA OA1200000136A patent/OA11378A/en unknown
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