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PT1019417E - Compostos analogos de fosfolipidos - Google Patents

Compostos analogos de fosfolipidos

Info

Publication number
PT1019417E
PT1019417E PT98945258T PT98945258T PT1019417E PT 1019417 E PT1019417 E PT 1019417E PT 98945258 T PT98945258 T PT 98945258T PT 98945258 T PT98945258 T PT 98945258T PT 1019417 E PT1019417 E PT 1019417E
Authority
PT
Portugal
Prior art keywords
integer
alkyl
carbon atoms
atoms
radical
Prior art date
Application number
PT98945258T
Other languages
English (en)
Inventor
Eibl Prof Dr Hansjorg
Original Assignee
Max Planck Ges Zur Forderung W
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19735776A external-priority patent/DE19735776A1/de
Application filed by Max Planck Ges Zur Forderung W filed Critical Max Planck Ges Zur Forderung W
Publication of PT1019417E publication Critical patent/PT1019417E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Dispersion Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • External Artificial Organs (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT98945258T 1997-08-18 1998-08-18 Compostos analogos de fosfolipidos PT1019417E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19735776A DE19735776A1 (de) 1996-06-03 1997-08-18 Phospholipidanaloge Verbindungen

Publications (1)

Publication Number Publication Date
PT1019417E true PT1019417E (pt) 2003-03-31

Family

ID=7839317

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98945258T PT1019417E (pt) 1997-08-18 1998-08-18 Compostos analogos de fosfolipidos

Country Status (10)

Country Link
US (6) US6344576B1 (pt)
EP (1) EP1019417B1 (pt)
JP (2) JP4550271B2 (pt)
AT (1) ATE226210T1 (pt)
AU (1) AU9263298A (pt)
DE (1) DE59805997D1 (pt)
DK (1) DK1019417T3 (pt)
ES (1) ES2181269T3 (pt)
PT (1) PT1019417E (pt)
WO (1) WO1999009037A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1019417E (pt) * 1997-08-18 2003-03-31 Max Planck Ges Zur Forderung W Compostos analogos de fosfolipidos
DE19835611A1 (de) * 1998-08-06 2000-02-10 Max Planck Gesellschaft Neuartige Phospholipide mit synthetischen, ungesättigten Alkyl- und Acylketten
DE10148066A1 (de) * 2001-09-28 2003-04-24 Max Planck Gesellschaft Liposome enthaltend (Ether)-Lysolecithine
EP1300161A1 (en) * 2001-10-08 2003-04-09 Rubitec Gesellschaft für Innovation und Technologie der Ruhr-Universität Bochum mbH Cationic lipids suitable for gene transfer
ES2184650B1 (es) * 2001-10-10 2004-09-16 Farmaleis, S.L. Utilizacion de colesterol y fosfolipidos en medicamentos para el tratamiento de la leishmaniasis en los canidos.
WO2003082882A1 (fr) * 2002-03-29 2003-10-09 Nof Corporation Derive phospholipidique
DE10221183A1 (de) * 2002-05-13 2003-12-04 Max Planck Gesellschaft Phosphatidyl-oligo-glycerine und Strukturanaloga
US7531604B2 (en) * 2002-09-30 2009-05-12 Nof Corporation Phospholipid derivative
WO2004041167A2 (en) * 2002-10-30 2004-05-21 Theodora Calogeropoulou Antiprotozoal ring-substituted phospholipids
CN100339382C (zh) * 2003-01-06 2007-09-26 日本油脂株式会社 磷脂质衍生物及其制造方法
US20060116354A1 (en) * 2003-01-09 2006-06-01 Perkins Walter R Antineoplastic ether lipid compounds with modifications at the sn-3 carbon
WO2004083219A1 (ja) * 2003-03-20 2004-09-30 Nof Corporation リン脂質誘導体
KR100769546B1 (ko) * 2005-06-28 2007-10-31 주식회사 메디슨 2d 초음파 영상을 이용한 3d 초음파 영상 형성 방법 및초음파 진단 시스템
US9567357B2 (en) * 2011-06-24 2017-02-14 Biointeractions Ltd. Biocompatible, biomimetic ampholyte materials

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE240020C (pt) *
DE2033357C3 (de) 1970-07-06 1980-02-14 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Palmitoyl-propandioKl 3)-phosphorsäure-S-trimethylaminophenylester und Verfahren zu dessen Herstellung
US4086257A (en) * 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
DE2752553C2 (de) 1977-11-24 1985-07-25 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Neue phospholipidartige Verbindungen, ihre Verwendung zur Herstellung von Pflanzenhybriden und Verfahren zu ihrer Herstellung
EP0032622B1 (en) 1979-12-20 1985-08-14 Dennis Chapman Polymerisable phospholipids and polymers thereof, methods for their preparation, methods for their use in coating substrates and forming liposomes and the resulting coated substrates and liposome compositions
JPS56135492A (en) * 1979-12-20 1981-10-22 Chiyatsupuman Denisu Biocompatible surfaces
DE3340950A1 (de) * 1983-11-11 1985-05-23 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur gewinnung von cholesterinesterase
US4774085A (en) * 1985-07-09 1988-09-27 501 Board of Regents, Univ. of Texas Pharmaceutical administration systems containing a mixture of immunomodulators
DD240020A1 (de) * 1985-08-02 1986-10-15 Univ Leipzig Verfahren zur herstellung neuer, pharmakologisch hochwirksamer phospholipide
SE8601457D0 (sv) * 1986-04-01 1986-04-01 Draco Ab Compositions of liposomes and b?712-receptor active substances for inhalation
EP0252004A1 (de) 1986-06-26 1988-01-07 Ciba-Geigy Ag Pharmazeutische Zusammensetzungen für die parenterale Applikation
US4916118A (en) * 1986-08-18 1990-04-10 Board Of Regents, The University Of Texas System Pharmaceutical administration systems containing chemotactic peptides
PT85537B (pt) 1986-08-18 1990-06-29 Univ Texas Processo para a preparacao de um sistema de administracao farmaceutica contendo peptidos apresentando quimiotaxia
US4931195A (en) * 1987-07-15 1990-06-05 Colgate-Palmolive Company Low viscosity stable non-aqueous suspension containing organophilic clay and low density filler
IL93925A0 (en) 1989-03-29 1990-12-23 Alcon Lab Inc Pharmaceutical compositions containing a monoacyl phosphogylceride
ES2060184T3 (es) * 1989-06-22 1994-11-16 Atta Moleculas anfifilicas conteniendo fluor y fosforo con propiedades tensoactivas.
US5270053A (en) * 1990-04-03 1993-12-14 Ciba-Geigy Corp. Parenterally administerable liposome formulation comprising synthetic lipid
JP2869572B2 (ja) * 1990-05-14 1999-03-10 和光純薬工業株式会社 ホスファチジルコリン誘導体の製造方法
EP0467838A3 (en) 1990-07-17 1992-09-02 Ciba-Geigy Ag Process for preparing an injectable liposome dispersion
JPH04356417A (ja) * 1990-09-26 1992-12-10 Kao Corp 静脈注射用脂肪乳剤
WO1993022320A1 (en) 1992-04-24 1993-11-11 Biocompatibles Limited Metal coatings
JPH06157311A (ja) 1992-11-16 1994-06-03 Eisai Co Ltd 血管病変治療剤
JPH06228012A (ja) * 1993-01-29 1994-08-16 Dai Ichi Seiyaku Co Ltd リポソーム製剤
JPH0753381A (ja) * 1993-07-09 1995-02-28 Ciba Geigy Ag 局所投与可能な亜鉛フタロシアニン組成物
GB9501286D0 (en) 1995-01-24 1995-03-15 Ciba Geigy Ag Pharmaceutical compositions and preparations thereof
DE19505894A1 (de) * 1995-02-21 1996-08-22 Boehringer Mannheim Gmbh Verfahren und Reagenz zur spezifischen Bestimmung von LDL in Serumproben
WO1997030058A1 (de) * 1996-02-16 1997-08-21 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Phosphatidyloligoglycerine
US5876480A (en) * 1996-02-20 1999-03-02 The United States Of America As Represented By The Secretary Of The Navy Synthesis of unagglomerated metal nano-particles at membrane interfaces
PT936860E (pt) 1996-10-25 2002-07-31 Monsanto Technology Llc Composicao e metodo para tratamento de plantas com quimicos exogenos
PT1019417E (pt) * 1997-08-18 2003-03-31 Max Planck Ges Zur Forderung W Compostos analogos de fosfolipidos
US6583251B1 (en) * 1997-09-08 2003-06-24 Emory University Modular cytomimetic biomaterials, transport studies, preparation and utilization thereof

Also Published As

Publication number Publication date
US6344576B1 (en) 2002-02-05
JP4550271B2 (ja) 2010-09-22
US8497388B2 (en) 2013-07-30
US6828453B2 (en) 2004-12-07
US7939683B2 (en) 2011-05-10
US20030198663A1 (en) 2003-10-23
US20100183705A1 (en) 2010-07-22
AU9263298A (en) 1999-03-08
EP1019417B1 (de) 2002-10-16
JP4714289B2 (ja) 2011-06-29
WO1999009037A1 (de) 1999-02-25
JP2001515082A (ja) 2001-09-18
JP2010018625A (ja) 2010-01-28
US20120009246A1 (en) 2012-01-12
ES2181269T3 (es) 2003-02-16
EP1019417A1 (de) 2000-07-19
US7595411B2 (en) 2009-09-29
ATE226210T1 (de) 2002-11-15
DK1019417T3 (da) 2003-02-17
US6545169B1 (en) 2003-04-08
DE59805997D1 (de) 2002-11-21
US20050165245A1 (en) 2005-07-28

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