PT100606A - Derivados fluoroalcoxibenzilamino de heterociclos contendo azoto - Google Patents

Derivados fluoroalcoxibenzilamino de heterociclos contendo azoto

Info

Publication number: PT100606A
Authority: PT; Portugal
Prior art keywords: pct; nitrogen containing; derivatives; fluoroalcoxibenzylamino; containing heterocycles
Prior art date: 1991-06-20

Application number

PT100606A

Other languages

English (en)

Other versions

PT100606B (pt

Inventor

Terry Jay Rosen

John Adams Lowe Iii

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-20

Filing date

1992-06-19

Publication date

1993-08-31

1992-06-19 Application filed by Pfizer filed Critical Pfizer

1993-08-31 Publication of PT100606A publication Critical patent/PT100606A/pt

1999-10-29 Publication of PT100606B publication Critical patent/PT100606B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Anesthesiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Indole Compounds (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

PT100606A 1991-06-20 1992-06-19 Derivados fluoroalcoxibenzilamino de heterociclos contendo azoto PT100606B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US71794391A	1991-06-20	1991-06-20

Publications (2)

Publication Number	Publication Date
PT100606A true PT100606A (pt)	1993-08-31
PT100606B PT100606B (pt)	1999-10-29

Family

ID=24884155

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT100606A PT100606B (pt)	1991-06-20	1992-06-19	Derivados fluoroalcoxibenzilamino de heterociclos contendo azoto

Country Status (32)

Country	Link
US (3)	US5773450A (pt)
EP (1)	EP0589924B1 (pt)
JP (1)	JPH07110850B2 (pt)
KR (1)	KR0154882B1 (pt)
CN (1)	CN1056373C (pt)
AT (1)	ATE142199T1 (pt)
AU (1)	AU657967B2 (pt)
BR (2)	BR9206161A (pt)
CA (1)	CA2109613C (pt)
CZ (1)	CZ290475B6 (pt)
DE (2)	DE9290083U1 (pt)
DK (1)	DK0589924T3 (pt)
EG (1)	EG20280A (pt)
ES (1)	ES2092113T3 (pt)
FI (3)	FI108794B (pt)
GR (1)	GR3021411T3 (pt)
HK (1)	HK1000247A1 (pt)
HU (2)	HU221634B1 (pt)
IE (1)	IE921986A1 (pt)
IL (1)	IL102188A (pt)
MX (1)	MX9203018A (pt)
NO (1)	NO180715C (pt)
NZ (1)	NZ243230A (pt)
PL (2)	PL170516B1 (pt)
PT (1)	PT100606B (pt)
RU (1)	RU2114848C1 (pt)
SK (1)	SK282203B6 (pt)
TW (1)	TW201301B (pt)
UA (1)	UA39168C2 (pt)
WO (1)	WO1993000331A1 (pt)
YU (1)	YU48997B (pt)
ZA (1)	ZA924528B (pt)

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FR2728169A1 (fr)	1994-12-19	1996-06-21	Oreal	Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
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GB9505692D0 (en) *	1995-03-21	1995-05-10	Glaxo Group Ltd	Chemical compounds
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WO1997013514A1 (en)	1995-10-10	1997-04-17	Pfizer Inc.	Nk-1 receptor antagonists for prevention of neurogenic inflammation in gene therapy
TW458774B (en)	1995-10-20	2001-10-11	Pfizer	Antiemetic pharmaceutical compositions
FR2741262B1 (fr)	1995-11-20	1999-03-05	Oreal	Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
EP0780375B1 (en)	1995-12-21	2002-09-11	Pfizer Inc.	3-((5-substituted benzyl)amino)-2-phenylpiperidines as substance p antagonists
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1992
- 1992-05-05 ES ES92911210T patent/ES2092113T3/es not_active Expired - Lifetime
- 1992-05-05 DK DK92911210.0T patent/DK0589924T3/da active
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- 1992-05-05 DE DE9290083U patent/DE9290083U1/de not_active Expired - Lifetime
- 1992-05-05 UA UA93004396A patent/UA39168C2/uk unknown
- 1992-05-05 US US08/167,881 patent/US5773450A/en not_active Expired - Fee Related
- 1992-05-05 CZ CS19923908A patent/CZ290475B6/cs not_active IP Right Cessation
- 1992-05-05 RU RU93058531A patent/RU2114848C1/ru not_active IP Right Cessation
- 1992-05-05 PL PL92310851A patent/PL170516B1/pl not_active IP Right Cessation
- 1992-05-05 WO PCT/US1992/003571 patent/WO1993000331A1/en active IP Right Grant
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1993
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Also Published As

Publication number	Publication date
HUT70499A (en)	1995-10-30
FI990419A (fi)	1999-02-26
PL170516B1 (en)	1996-12-31
PL172054B1 (pl)	1997-07-31
SK282203B6 (sk)	2001-12-03
EG20280A (en)	1998-07-30
JPH07110850B2 (ja)	1995-11-29
FI935701A0 (fi)	1993-12-17
FI935701A (fi)	1993-12-17
NO934691D0 (no)	1993-12-17
CZ390892A3 (en)	1994-04-13
US5744480A (en)	1998-04-28
HU9303668D0 (en)	1994-04-28
ES2092113T3 (es)	1996-11-16
DE69213451D1 (de)	1996-10-10
MX9203018A (es)	1993-07-01
HUT67434A (en)	1995-04-28
NO180715C (no)	1997-06-04
FI990418A0 (fi)	1999-02-26
RU2114848C1 (ru)	1998-07-10
HU224443B1 (hu)	2005-09-28
IL102188A (en)	2002-12-01
KR0154882B1 (ko)	1998-11-16
DE9290083U1 (de)	1994-02-17
NZ243230A (en)	1997-06-24
FI990418A (fi)	1999-02-26
FI990419A0 (fi)	1999-02-26
FI110686B (fi)	2003-03-14
ATE142199T1 (de)	1996-09-15
PT100606B (pt)	1999-10-29
HK1000247A1 (en)	1998-02-13
US20030199540A1 (en)	2003-10-23
HU221634B1 (hu)	2002-12-28
ZA924528B (en)	1993-12-20
YU64092A (sh)	1995-03-27
AU1889392A (en)	1993-01-25
EP0589924B1 (en)	1996-09-04
BR9206161A (pt)	1995-10-31
UA39168C2 (uk)	2001-06-15
US5773450A (en)	1998-06-30
BR1100086A (pt)	2000-07-25
SK390892A3 (en)	1995-09-13
IL102188A0 (en)	1993-01-14
YU48997B (sh)	2003-04-30
FI108794B (fi)	2002-03-28
CA2109613C (en)	1996-11-19
EP0589924A1 (en)	1994-04-06
GR3021411T3 (en)	1997-01-31
TW201301B (pt)	1993-03-01
HU9500836D0 (en)	1995-05-29
KR940701383A (ko)	1994-05-28
NO934691L (no)	1993-12-17
CA2109613A1 (en)	1993-01-07
CN1056373C (zh)	2000-09-13
AU657967B2 (en)	1995-03-30
NO180715B (no)	1997-02-24
DK0589924T3 (da)	1996-09-30
IE921986A1 (en)	1992-12-30
DE69213451T2 (de)	1997-01-09
CZ290475B6 (cs)	2002-07-17
WO1993000331A1 (en)	1993-01-07
JPH06506473A (ja)	1994-07-21
CN1067655A (zh)	1993-01-06

Publication	Publication Date	Title
BR1100086A (pt)	2000-07-25	Derivados de fluoralcóxibenzilamino de heterocìclos contendo nitrogênio
FI941212A0 (fi)	1994-03-15	Fuusioituneet trisykliset, typpeä sisältävät heterosykliset yhdisteet
CA2111461A1 (en)	1993-01-21	3-Aminopiperidine Derivatives and Related Nitrogen Containing Heterocycles
MX9203053A (es)	1992-12-01	Derivados de aza nor bornano.
MX9206499A (es)	1993-05-01	Derivados de etilendiamina aciclica

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